Regioselective ortho-hydroxylation of aryl moiety of 2-arylpyridines using Pd(OAc)2/Oxone in PEG-3400/tert-BuOH

Tetrahedron Letters

Volumn 49, Issue 41, 2008, Pages 5863-5866

  Kim, Sung Hwan ^a   Lee, Hyun Seung ^a   Kim, Se Hee ^a   Kim, Jae Nyoung ^a  

^a Chonnam National University   (South Korea)

Author keywords

2 Arylpyridines; Baylis Hillman adducts; Hydroxylation; Oxone; Pd(OAc)2

Indexed keywords

2 PYRIDINE; MACROGOL 3400; MACROGOL DERIVATIVE; OXONE (POTASSIUMPEROXYMONOSULFATE); PALLADIUM; POLYCYCLIC AROMATIC HYDROCARBON DERIVATIVE; PYRIDINE DERIVATIVE; TERT BUTYL HYDROPEROXIDE; UNCLASSIFIED DRUG;

ARTICLE; HYDROXYLATION; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

EID: 50049104417     PISSN: 00404039     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tetlet.2008.07.141     Document Type: Article

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38. ++1).
39. 2 (30% solution) instead of Oxone produced 7a in trace amounts (<10%).
40. 2b was isolated in 20%).
41. 4c