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Volumn 36, Issue 8, 2008, Pages 2388-2394

Phlebotomies or erythropoietin injections allow mobilization of iron stores in a mouse model mimicking intensive care anemia

Author keywords

Anemia; Erythropoietin; Ferroportin; Hepcidin; Intensive care; Iron

Indexed keywords

DIAMINOBENZIDINE; ERYTHROPOIETIN; FERRITIN; FERROPORTIN; HEPCIDIN; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MESSENGER RNA; NONHEME IRON PROTEIN; ZYMOSAN; ANTIMICROBIAL CATIONIC PEPTIDE; CATION TRANSPORT PROTEIN; IRON; METAL TRANSPORTING PROTEIN 1;

EID: 49949085724     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31818103b9     Document Type: Article
Times cited : (70)

References (37)
  • 1
    • 0037174359 scopus 로고    scopus 로고
    • Anemia and blood transfusion in critically ill patients
    • Vincent JL, Baron JF, Reinhart K, et al: Anemia and blood transfusion in critically ill patients. JAMA 2002; 288:1499-1507
    • (2002) JAMA , vol.288 , pp. 1499-1507
    • Vincent, J.L.1    Baron, J.F.2    Reinhart, K.3
  • 2
    • 9144245515 scopus 로고    scopus 로고
    • The CRIT Study: Anemia and blood transfusion in the critically ill - Current clinical practice in the United States
    • Corwin HL, Gettinger A, Pearl RG, et al: The CRIT Study: Anemia and blood transfusion in the critically ill - Current clinical practice in the United States. Crit Care Med 2004; 32: 39-52
    • (2004) Crit Care Med , vol.32 , pp. 39-52
    • Corwin, H.L.1    Gettinger, A.2    Pearl, R.G.3
  • 3
    • 0343360868 scopus 로고    scopus 로고
    • A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion requirements in critical care investigators, Canadian Critical Care Trials Group
    • Hebert PC, Wells G, Blajchman MA, et al: A multicenter, randomized, controlled clinical trial of transfusion requirements in critical care. Transfusion requirements in critical care investigators, Canadian Critical Care Trials Group. N Engl J Med 1999; 340: 409-417
    • (1999) N Engl J Med , vol.340 , pp. 409-417
    • Hebert, P.C.1    Wells, G.2    Blajchman, M.A.3
  • 4
    • 0033847343 scopus 로고    scopus 로고
    • Anemia of the critically ill: "Acute" anemia of chronic disease
    • Corwin HL, Krantz SB: Anemia of the critically ill: "Acute" anemia of chronic disease. Crit Care Med 2000; 28:3098-3099
    • (2000) Crit Care Med , vol.28 , pp. 3098-3099
    • Corwin, H.L.1    Krantz, S.B.2
  • 5
    • 14744278436 scopus 로고    scopus 로고
    • Anemia of chronic disease
    • Weiss G, Goodnough LT: Anemia of chronic disease. N Engl J Med 2005; 352:1011-1023
    • (2005) N Engl J Med , vol.352 , pp. 1011-1023
    • Weiss, G.1    Goodnough, L.T.2
  • 6
    • 0023044723 scopus 로고
    • Medical vampires
    • Burnum JF: Medical vampires. N Engl J Med 1986; 314:1250-1251
    • (1986) N Engl J Med , vol.314 , pp. 1250-1251
    • Burnum, J.F.1
  • 7
    • 0037329683 scopus 로고    scopus 로고
    • Time course of hemoglobin concentrations in non-bleeding intensive care unit patients
    • Nguyen BV, Bota DP, Melot C, et al: Time course of hemoglobin concentrations in non-bleeding intensive care unit patients. Crit Care Med 2003; 31:406-410
    • (2003) Crit Care Med , vol.31 , pp. 406-410
    • Nguyen, B.V.1    Bota, D.P.2    Melot, C.3
  • 8
    • 0033397526 scopus 로고    scopus 로고
    • Important role of nondiagnostic blood loss and blunted erythropoietic response in the anemia of medical intensive care patients
    • von Ahsen N, Muller C, Serke S, et al: Important role of nondiagnostic blood loss and blunted erythropoietic response in the anemia of medical intensive care patients. Crit Care Med 1999; 27:2630-2639
    • (1999) Crit Care Med , vol.27 , pp. 2630-2639
    • von Ahsen, N.1    Muller, C.2    Serke, S.3
  • 9
    • 33750933743 scopus 로고    scopus 로고
    • Erythropoiesis in multiply injured patients
    • Robinson Y, Hostmann A, Matenov A, et al: Erythropoiesis in multiply injured patients. J Trauma 2006; 61:1285-1291
    • (2006) J Trauma , vol.61 , pp. 1285-1291
    • Robinson, Y.1    Hostmann, A.2    Matenov, A.3
  • 10
    • 7944226815 scopus 로고    scopus 로고
    • Bench-to-bedside review: Iron metabolism in critically ill patients
    • Darveau M, Denault AY, Blais N, et al: Bench-to-bedside review: Iron metabolism in critically ill patients. Crit Care 2004; 8:356-362
    • (2004) Crit Care , vol.8 , pp. 356-362
    • Darveau, M.1    Denault, A.Y.2    Blais, N.3
  • 11
    • 0035896642 scopus 로고    scopus 로고
    • Hepcidin, a urinary antimicrobial peptide synthesized in the liver
    • Park CH, Valore EV, Waring AJ, et al: Hepcidin, a urinary antimicrobial peptide synthesized in the liver. J Biol Chem 2001; 276: 7806-7810
    • (2001) J Biol Chem , vol.276 , pp. 7806-7810
    • Park, C.H.1    Valore, E.V.2    Waring, A.J.3
  • 13
    • 0041672570 scopus 로고    scopus 로고
    • Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation
    • Ganz T: Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation. Blood 2003; 102:783-788
    • (2003) Blood , vol.102 , pp. 783-788
    • Ganz, T.1
  • 14
    • 4344600507 scopus 로고    scopus 로고
    • Hepcidin in iron metabolism
    • Ganz T: Hepcidin in iron metabolism. Curr Opin Hematol 2004; 11:251-254
    • (2004) Curr Opin Hematol , vol.11 , pp. 251-254
    • Ganz, T.1
  • 15
    • 0034677467 scopus 로고    scopus 로고
    • Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter
    • Donovan A, Brownlie A, Zhou Y, et al: Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature 2000; 403:776-781
    • (2000) Nature , vol.403 , pp. 776-781
    • Donovan, A.1    Brownlie, A.2    Zhou, Y.3
  • 16
    • 10844258104 scopus 로고    scopus 로고
    • Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internaliza-tion
    • Nemeth E, Tuttle MS, Powelson J, et al: Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internaliza-tion. Science 2004; 306:2090-2093
    • (2004) Science , vol.306 , pp. 2090-2093
    • Nemeth, E.1    Tuttle, M.S.2    Powelson, J.3
  • 17
    • 28444488323 scopus 로고    scopus 로고
    • The presence of the iron exporter ferroportin at the plasma membrane of macrophages is enhanced by iron loading and downregulated by hepcidin
    • Delaby C, Pilard N, Goncalves AS, et al: The presence of the iron exporter ferroportin at the plasma membrane of macrophages is enhanced by iron loading and downregulated by hepcidin. Blood 2005; 106:3979-3984
    • (2005) Blood , vol.106 , pp. 3979-3984
    • Delaby, C.1    Pilard, N.2    Goncalves, A.S.3
  • 18
    • 0033838942 scopus 로고    scopus 로고
    • Response of erythropoiesis and iron metabolism to recombinant human erythropoietin in intensive care unit patients
    • van Iperen CE, Gaillard CA, Kraaijenhagen RJ, et al: Response of erythropoiesis and iron metabolism to recombinant human erythropoietin in intensive care unit patients. Crit Care Med 2000; 28:2773-2778
    • (2000) Crit Care Med , vol.28 , pp. 2773-2778
    • van Iperen, C.E.1    Gaillard, C.A.2    Kraaijenhagen, R.J.3
  • 19
    • 0032512324 scopus 로고    scopus 로고
    • Unrecognized iron deficiency in critical illness
    • Bellamy MC, Gedney JA: Unrecognized iron deficiency in critical illness. Lancet 1998; 352:1903
    • (1998) Lancet , vol.352 , pp. 1903
    • Bellamy, M.C.1    Gedney, J.A.2
  • 20
    • 0036791486 scopus 로고    scopus 로고
    • The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
    • Nicolas G, Chauvet C, Viatte L, et al: The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest 2002; 110: 1037-1044
    • (2002) J Clin Invest , vol.110 , pp. 1037-1044
    • Nicolas, G.1    Chauvet, C.2    Viatte, L.3
  • 21
    • 33845245942 scopus 로고    scopus 로고
    • Suppression of hepcidin during anemia requires erythropoietic activity
    • Pak M, Lopez MA, Gabayan V, et al: Suppression of hepcidin during anemia requires erythropoietic activity. Blood 2006; 108: 3730-3735
    • (2006) Blood , vol.108 , pp. 3730-3735
    • Pak, M.1    Lopez, M.A.2    Gabayan, V.3
  • 22
    • 16244372427 scopus 로고    scopus 로고
    • Zymosan-induced generalized inflammation: Experimental studies into mechanisms leading to multiple organ dysfunction syndrome
    • Volman TJ, Hendriks T, Goris RJ: Zymosan-induced generalized inflammation: Experimental studies into mechanisms leading to multiple organ dysfunction syndrome. Shock 2005; 23:291-297
    • (2005) Shock , vol.23 , pp. 291-297
    • Volman, T.J.1    Hendriks, T.2    Goris, R.J.3
  • 23
    • 3042662412 scopus 로고    scopus 로고
    • Tissue- and time-dependent upregulation of cytokine mRNA in a murine model for the multiple organ dysfunction syndrome
    • Volman TJ, Goris RJ, van der Meer JW, et al: Tissue- and time-dependent upregulation of cytokine mRNA in a murine model for the multiple organ dysfunction syndrome. Ann Surg 2004; 240:142-150
    • (2004) Ann Surg , vol.240 , pp. 142-150
    • Volman, T.J.1    Goris, R.J.2    van der Meer, J.W.3
  • 24
    • 33645525540 scopus 로고    scopus 로고
    • Chronic hepcidin induction causes hyposideremia and alters the pattern of cellular iron accumulation in hemochromatotic mice
    • Viatte L, Nicolas G, Lou DQ, et al: Chronic hepcidin induction causes hyposideremia and alters the pattern of cellular iron accumulation in hemochromatotic mice. Blood 2006; 107:2952-2958
    • (2006) Blood , vol.107 , pp. 2952-2958
    • Viatte, L.1    Nicolas, G.2    Lou, D.Q.3
  • 25
    • 0035902605 scopus 로고    scopus 로고
    • Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice
    • Nicolas G, Bennoun M, Devaux I, et al: Lack of hepcidin gene expression and severe tissue iron overload in upstream stimulatory factor 2 (USF2) knockout mice. Proc Natl Acad Sci USA 2001; 98:8780-8785
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 8780-8785
    • Nicolas, G.1    Bennoun, M.2    Devaux, I.3
  • 26
    • 0037528706 scopus 로고    scopus 로고
    • Iron transport by Nramp2/DMT1: PH regulation of transport by 2 histidines in transmembrane domain 6
    • Lam-Yuk-Tseung S, Govoni G, Forbes J, et al: Iron transport by Nramp2/DMT1: pH regulation of transport by 2 histidines in transmembrane domain 6. Blood 2003; 101: 3699-3707
    • (2003) Blood , vol.101 , pp. 3699-3707
    • Lam-Yuk-Tseung, S.1    Govoni, G.2    Forbes, J.3
  • 27
    • 4444232740 scopus 로고    scopus 로고
    • Transferrin receptor 1 mRNA is downregulated in placenta of hepcidin transgenic embryos
    • Martin ME, Nicolas G, Hetet G, et al: Transferrin receptor 1 mRNA is downregulated in placenta of hepcidin transgenic embryos. FEBS Lett 2004; 574:187-191
    • (2004) FEBS Lett , vol.574 , pp. 187-191
    • Martin, M.E.1    Nicolas, G.2    Hetet, G.3
  • 28
    • 2342510407 scopus 로고    scopus 로고
    • IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin
    • Nemeth E, Rivera S, Gabayan V, et al: IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest 2004; 113: 1271-1276
    • (2004) J Clin Invest , vol.113 , pp. 1271-1276
    • Nemeth, E.1    Rivera, S.2    Gabayan, V.3
  • 29
    • 13844307889 scopus 로고    scopus 로고
    • Regulation of hepcidin transcription by interleukin-1 and interleukin-6
    • Lee P, Peng H, Gelbart T, et al: Regulation of hepcidin transcription by interleukin-1 and interleukin-6. Proc Natl Acad Sci USA 2005; 102:1906-1910
    • (2005) Proc Natl Acad Sci USA , vol.102 , pp. 1906-1910
    • Lee, P.1    Peng, H.2    Gelbart, T.3
  • 30
    • 23944502314 scopus 로고    scopus 로고
    • Timecourse analysis of hepcidin, serum iron, and plasma cytokine levels in humans injected with LPS
    • Kemna E, Pickkers P, Nemeth E, et al: Timecourse analysis of hepcidin, serum iron, and plasma cytokine levels in humans injected with LPS. Blood 2005; 106:1864-1866
    • (2005) Blood , vol.106 , pp. 1864-1866
    • Kemna, E.1    Pickkers, P.2    Nemeth, E.3
  • 31
    • 33745742487 scopus 로고    scopus 로고
    • Hepcidin mRNA levels in mouse liver respond to inhibition of erythropoiesis
    • Vokurka M, Krijt J, Sulc K, et al: Hepcidin mRNA levels in mouse liver respond to inhibition of erythropoiesis. Physiol Res 2006; 55:667-674
    • (2006) Physiol Res , vol.55 , pp. 667-674
    • Vokurka, M.1    Krijt, J.2    Sulc, K.3
  • 32
    • 34748925835 scopus 로고    scopus 로고
    • Erythropoietin-receptor agonists in critically ill patients: A meta-analysis of randomized controlled trials
    • Zarychanski R, Turgeon AF, McIntyre L, et al: Erythropoietin-receptor agonists in critically ill patients: A meta-analysis of randomized controlled trials. CMAJ 2007; 177:725-734
    • (2007) CMAJ , vol.177 , pp. 725-734
    • Zarychanski, R.1    Turgeon, A.F.2    McIntyre, L.3
  • 33
    • 34548418912 scopus 로고    scopus 로고
    • Efficacy and safety of epoetin alfa in critically ill patients
    • Corwin HL, Gettinger A, Fabian TC, et al: Efficacy and safety of epoetin alfa in critically ill patients. N Engl J Med 2007; 357:965-976
    • (2007) N Engl J Med , vol.357 , pp. 965-976
    • Corwin, H.L.1    Gettinger, A.2    Fabian, T.C.3
  • 34
    • 0032934971 scopus 로고    scopus 로고
    • Pharmacokinetics and red cell utilization of iron(III) hydroxide-sucrose complex in anemic patients: A study using positron emission tomography
    • Beshara S, Lundqvist H, Sundin J, et al: Pharmacokinetics and red cell utilization of iron(III) hydroxide-sucrose complex in anemic patients: A study using positron emission tomography. Br J Haematol 1999; 104:296 -302
    • (1999) Br J Haematol , vol.104 , pp. 296-302
    • Beshara, S.1    Lundqvist, H.2    Sundin, J.3
  • 35
    • 33847046008 scopus 로고    scopus 로고
    • Intravenous ferric gluconate significantly improves response to epoetin alfa versus oral iron or no iron in anemic patients with cancer receiving chemotherapy
    • Henry DH, Dahl NV, Auerbach M, et al: Intravenous ferric gluconate significantly improves response to epoetin alfa versus oral iron or no iron in anemic patients with cancer receiving chemotherapy. Oncologist 2007; 12:231-242
    • (2007) Oncologist , vol.12 , pp. 231-242
    • Henry, D.H.1    Dahl, N.V.2    Auerbach, M.3
  • 36
    • 2142825053 scopus 로고    scopus 로고
    • Intravenous iron optimizes the response to recombinant human erythropoietin in cancer patients with chemotherapy-related anemia: A multicenter, open-label, randomized trial
    • Auerbach M, Ballard H, Trout JR, et al: Intravenous iron optimizes the response to recombinant human erythropoietin in cancer patients with chemotherapy-related anemia: A multicenter, open-label, randomized trial. J Clin Oncol 2004; 22: 1301-1307
    • (2004) J Clin Oncol , vol.22 , pp. 1301-1307
    • Auerbach, M.1    Ballard, H.2    Trout, J.R.3
  • 37
    • 33947405774 scopus 로고    scopus 로고
    • Addition of intravenous iron to epoetin beta increases hemoglobin response and decreases epoetin dose requirement in anemic patients with lymphoproliferative malignancies: A randomized multicenter study
    • Hedenus M, Birgegard G, Nasman P, et al: Addition of intravenous iron to epoetin beta increases hemoglobin response and decreases epoetin dose requirement in anemic patients with lymphoproliferative malignancies: A randomized multicenter study. Leukemia 2007; 21:627-632
    • (2007) Leukemia , vol.21 , pp. 627-632
    • Hedenus, M.1    Birgegard, G.2    Nasman, P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.