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Volumn 21, Issue , 2005, Pages 396-403

Gene expression profiling demonstrates that TGF-β1 signals exclusively through receptor complexes involving Alk5 and identifies targets of TGF-β signaling

Author keywords

Microarrays; Signal transduction; Smad

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN ACTIVIN LIKE KINASE RECEPTOR 5; RECEPTOR PROTEIN; SMAD PROTEIN; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 2; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

EID: 21244489290     PISSN: 15312267     EISSN: None     Source Type: Journal    
DOI: 10.1152/physiolgenomics.00303.2004     Document Type: Article
Times cited : (31)

References (24)
  • 1
    • 0037331234 scopus 로고    scopus 로고
    • Global expression profiling of fibroblast responses to transforming growth factor-β1 reveals the induction of inhibitor of differentiation-1 and pro-vides evidence of smooth muscle cell phenotypic switching
    • Chambers RC, Leoni P, Kaminski N, Laurent GJ, and Heller RA. Global expression profiling of fibroblast responses to transforming growth factor-β1 reveals the induction of inhibitor of differentiation-1 and pro-vides evidence of smooth muscle cell phenotypic switching. Am J Pathol 162: 533-546, 2003.
    • (2003) Am J Pathol , vol.162 , pp. 533-546
    • Chambers, R.C.1    Leoni, P.2    Kaminski, N.3    Laurent, G.J.4    Heller, R.A.5
  • 2
    • 0036904895 scopus 로고    scopus 로고
    • Genetic analysis of the mammalian transforming growth factor-β superfamily
    • Chang H, Brown CW, and Matzuk MM. Genetic analysis of the mammalian transforming growth factor-β superfamily. Endocr Rev 23: 787-823, 2002.
    • (2002) Endocr Rev , vol.23 , pp. 787-823
    • Chang, H.1    Brown, C.W.2    Matzuk, M.M.3
  • 4
    • 0036343334 scopus 로고    scopus 로고
    • Overexpression of the type II transforming growth factor-β receptor inhibits fibroblasts proliferation and activates extracellular signal regulated kinase and c-Jun N-terminal kinase
    • Goldberg HJ, Huszar T, Mozes MM, Kosivall L, and Mucsi I. Overexpression of the type II transforming growth factor-β receptor inhibits fibroblasts proliferation and activates extracellular signal regulated kinase and c-Jun N-terminal kinase. Cell Biol Int 26: 165-174, 2002.
    • (2002) Cell Biol Int , vol.26 , pp. 165-174
    • Goldberg, H.J.1    Huszar, T.2    Mozes, M.M.3    Kosivall, L.4    Mucsi, I.5
  • 7
    • 0038369998 scopus 로고    scopus 로고
    • A self-enabling TGFβ response coupled to stress signaling: Smad engages stress response factor ATF3 for Id1 repression in epithelial cells
    • Kang Y, Chen CR, and Massague J. A self-enabling TGFβ response coupled to stress signaling: Smad engages stress response factor ATF3 for Id1 repression in epithelial cells. Mol Cell 11: 915-926, 2003.
    • (2003) Mol Cell , vol.11 , pp. 915-926
    • Kang, Y.1    Chen, C.R.2    Massague, J.3
  • 8
    • 0028988164 scopus 로고
    • The growth-inhibitory block of TGF-β is located close to the G1/S border in the cell cycle
    • Kletsas D, Stathakos D, Sorrentino V, and Philipson L. The growth-inhibitory block of TGF-β is located close to the G1/S border in the cell cycle. Exp Cell Res 217: 477-483, 1995.
    • (1995) Exp Cell Res , vol.217 , pp. 477-483
    • Kletsas, D.1    Stathakos, D.2    Sorrentino, V.3    Philipson, L.4
  • 11
    • 0037089442 scopus 로고    scopus 로고
    • Down-regulation of Id-1 expression is associated with TGFβ1-induced growth arrest in prostate epithelial cells
    • Ling MT, Wang X, Tsao SW, and Wong YC. Down-regulation of Id-1 expression is associated with TGFβ1-induced growth arrest in prostate epithelial cells. Biochim Biophys Acta 1570: 145-152, 2002.
    • (2002) Biochim Biophys Acta , vol.1570 , pp. 145-152
    • Ling, M.T.1    Wang, X.2    Tsao, S.W.3    Wong, Y.C.4
  • 12
    • 13244292283 scopus 로고    scopus 로고
    • Multiclass discovery in array data
    • Liu Y and Ringner M. Multiclass discovery in array data. BMC Bioinformatics 5: 70, 2004.
    • (2004) BMC Bioinformatics , vol.5 , pp. 70
    • Liu, Y.1    Ringner, M.2
  • 13
    • 0034644472 scopus 로고    scopus 로고
    • TGFβ signaling in growth control, cancer, and heritable disorders
    • Massague J, Blain SW, and Lo RS. TGFβ signaling in growth control, cancer, and heritable disorders. Cell 103: 295-309, 2000.
    • (2000) Cell , vol.103 , pp. 295-309
    • Massague, J.1    Blain, S.W.2    Lo, R.S.3
  • 14
    • 0038648463 scopus 로고    scopus 로고
    • Molecular profiling of hepatocellular carcinomas developing spontaneously in acyl-CoA oxidase-deficient mice: Comparison with liver tumors induced in wild-type mice by a peroxisome proliferator and a genotoxic carcinogen
    • Meyer K, Lee JS, Dyck PA, Cao WQ, Rao MS, Thorgeirsson SS, and Reddy JK. Molecular profiling of hepatocellular carcinomas developing spontaneously in acyl-CoA oxidase-deficient mice: comparison with liver tumors induced in wild-type mice by a peroxisome proliferator and a genotoxic carcinogen. Carcinogenesis 24: 975-984, 2003.
    • (2003) Carcinogenesis , vol.24 , pp. 975-984
    • Meyer, K.1    Lee, J.S.2    Dyck, P.A.3    Cao, W.Q.4    Rao, M.S.5    Thorgeirsson, S.S.6    Reddy, J.K.7
  • 15
    • 0025719982 scopus 로고
    • Cytokines in context
    • Nathan C and Sporn M. Cytokines in context. J Cell Biol 113: 981-986, 1991.
    • (1991) J Cell Biol , vol.113 , pp. 981-986
    • Nathan, C.1    Sporn, M.2
  • 18
    • 0031933224 scopus 로고    scopus 로고
    • Molecular and cell biology of TGF-β
    • Roberts AB. Molecular and cell biology of TGF-β. Miner Electrolyte Metab 24: 111-119, 1998.
    • (1998) Miner Electrolyte Metab , vol.24 , pp. 111-119
    • Roberts, A.B.1
  • 19
    • 0037099005 scopus 로고    scopus 로고
    • BioArray Software Environment (BASE): A platform for comprehensive management and analysis of microarray data
    • SOFTWARE0003
    • Saal LH, Troein C, Vallon-Christersson J, Gruvberger S, Borg A, and Peterson C. BioArray Software Environment (BASE): a platform for comprehensive management and analysis of microarray data. Genome Biol 3: SOFTWARE0003, 2002.
    • (2002) Genome Biol , vol.3
    • Saal, L.H.1    Troein, C.2    Vallon-Christersson, J.3    Gruvberger, S.4    Borg, A.5    Peterson, C.6
  • 20
    • 0042316912 scopus 로고    scopus 로고
    • Mad upregulation and Id2 repression accompany transforming growth factor (TGF)-β-mediated epithelial cell growth suppression
    • Siegel PM, Shu W, and Massague J. Mad upregulation and Id2 repression accompany transforming growth factor (TGF)-β-mediated epithelial cell growth suppression. J Biol Chem 278: 35444-35450, 2003.
    • (2003) J Biol Chem , vol.278 , pp. 35444-35450
    • Siegel, P.M.1    Shu, W.2    Massague, J.3
  • 21
    • 4744350841 scopus 로고    scopus 로고
    • Proteomic identification of Bcl2-associated athanogene 2 as a novel MAPK-activated protein kinase 2 substrate
    • Ueda K, Kosako H, Fukui Y, and Hattori S. Proteomic identification of Bcl2-associated athanogene 2 as a novel MAPK-activated protein kinase 2 substrate. J Biol Chem 279: 41815-41821, 2004.
    • (2004) J Biol Chem , vol.279 , pp. 41815-41821
    • Ueda, K.1    Kosako, H.2    Fukui, Y.3    Hattori, S.4
  • 22
    • 0035907240 scopus 로고    scopus 로고
    • Identification of novel TGF-β /Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach
    • Verrecchia F, Chu ML, and Mauviel A. Identification of novel TGF-β /Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach. J Biol Chem 276: 17058-17062, 2001.
    • (2001) J Biol Chem , vol.276 , pp. 17058-17062
    • Verrecchia, F.1    Chu, M.L.2    Mauviel, A.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.