A connection between the mitochondrial permeability transition pore, autophagy, and cerebral amyloidogenesis

Journal of Proteome Research

Volumn 7, Issue 6, 2008, Pages 2262-2269

  Šoškić, Vukić ^a   Kjemm, Martina ^a   Proikas Cezanne, Tassula ^b   Schwall, Gerhard P ^a   Poznanović, Slobodan ^a   Stegmann, Werner ^a   Groebe, Karlfried ^a   Zengerling, Helmut ^a   Schoepf, Rainer ^a   Burnet, Michael ^c   Schrattenholz, André ^a  

^a PROTEOSYS AG   (Germany)

^b UNIVERSITY OF TÜBINGEN   (Germany)

^c Synovo GmbH   (Germany)

Author keywords

Alzheimer's disease; Autophagy; Cerebral amyloidosis; Chemical proteomics; Drug repositioning; Dutasteride; Excitotoxicity; Finasteride; Mitochondrial; Systems biology

Indexed keywords

4ALPHA,6ALPHA DIMETHYL 2 OXOHEXADECAHYDROINDENO[5,4 F]QUINOLINE 7 CARBOXYLIC (2 AMINOETHYL)AMIDE; 4ALPHA,6ALPHA DIMETHYL 2 OXOHEXADECAHYDROINDENO[5,4 F]QUINOLINE 7 CARBOXYLIC ACID; ADENINE NUCLEOTIDE TRANSLOCASE; AMYLOID; AMYLOID BETA PROTEIN; AZASTEROID; DUTASTERIDE; FINASTERIDE; UNCLASSIFIED DRUG; AMYLOID PRECURSOR PROTEIN; CARRIER PROTEIN; ENZYME INHIBITOR; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; N METHYLASPARTIC ACID; NEUROPROTECTIVE AGENT; POTASSIUM CYANIDE; PRESENILIN; TESTOSTERONE;

AMYLOIDOSIS; ANIMAL CELL; APOPTOSIS; ARTICLE; AUTOPHAGY; CONTROLLED STUDY; DRUG STRUCTURE; HUMAN; HUMAN CELL; MITOCHONDRIAL PERMEABILITY; MOUSE; NEUROPROTECTION; NONHUMAN; PRIORITY JOURNAL; ANIMAL; BRAIN DISEASE; C57BL MOUSE; DISEASE MODEL; DRUG EFFECT; GENETICS; METABOLISM; NEOCORTEX; NERVE CELL; PATHOLOGY; SENILE PLAQUE; SEX DIFFERENCE; TRANSGENIC MOUSE;

AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOIDOSIS; ANIMALS; APOPTOSIS; AUTOPHAGY; AZASTEROIDS; BRAIN DISEASES; DISEASE MODELS, ANIMAL; ENZYME INHIBITORS; FINASTERIDE; HUMANS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOCHONDRIAL ADP, ATP TRANSLOCASES; MITOCHONDRIAL MEMBRANE TRANSPORT PROTEINS; N-METHYLASPARTATE; NEOCORTEX; NEURONS; NEUROPROTECTIVE AGENTS; POTASSIUM CYANIDE; PRESENILINS; SENILE PLAQUES; SEX FACTORS; TESTOSTERONE;

EID: 49849102306     PISSN: 15353893     EISSN: None     Source Type: Journal    
DOI: 10.1021/pr700686x     Document Type: Article

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