Synthesis of N-substituted piperidine-4-(benzylidene-4-carboxylic acids) and evaluation as inhibitors of steroid-5α-reductase type 1 and 2

Bioorganic and Medicinal Chemistry

Volumn 8, Issue 6, 2000, Pages 1479-1487

  Picard, Franck ^a   Baston, Eckhard ^a,b   Reichert, Wolfgang ^a   Hartmann, Rolf W ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b UNIVERSITY OF LAUSANNE   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLIC ACID DERIVATIVE; STEROID 5ALPHA REDUCTASE INHIBITOR; TESTOSTERONE PROPIONATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CASTRATION; DRUG SYNTHESIS; ENZYME INHIBITION; HUMAN; IC 50; MALE; NONHUMAN; PROSTATE; RAT;

ANIMALS; BENZENE; CARBOXYLIC ACIDS; ENZYME INHIBITORS; HUMANS; ISOENZYMES; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MOLECULAR STRUCTURE; PIPERIDINES; RATS; TESTOSTERONE 5-ALPHA-REDUCTASE; TUMOR CELLS, CULTURED;

EID: 0034053626     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(00)00070-5     Document Type: Article

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