Effects of propyl paraben on the male reproductive system

Food and Chemical Toxicology

Volumn 40, Issue 12, 2002, Pages 1807-1813

  Oishi, S ^a  

^a TOKYO METROPOLITAN INSTITUTE OF PUBLIC HEALTH   (Japan)

Author keywords

Acceptable daily intake (ADI); Paraben; Preservatives; Propyl paraben; Rat; Sperm; Testosterone

Indexed keywords

PROPYL PARABEN; TESTOSTERONE;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIETARY INTAKE; DOSE RESPONSE; EPIDIDYMIS; EPIDIDYMIS TAIL; EUROPE; HORMONE RELEASE; JAPAN; MALE; MALE GENITAL SYSTEM; NONHUMAN; ORGAN SIZE; PREPUTIAL GLAND; PROSTATE; RAT; REPRODUCTIVE TOXICITY; SEMINAL VESICLE; SPERM; SPERMATOGENESIS; TESTIS WEIGHT; TESTOSTERONE BLOOD LEVEL;

ANIMALS; DOSE-RESPONSE RELATIONSHIP, DRUG; FOOD PRESERVATIVES; GENITALIA, MALE; MALE; ORGAN SIZE; PARABENS; PRESERVATIVES, PHARMACEUTICAL; RATS; RATS, WISTAR; SPERM COUNT; SPERMATOGENESIS; TESTIS; TESTOSTERONE;

ANIMALIA; MAMMALIA;

EID: 0036888092     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(02)00204-1     Document Type: Article

References (61)

1. Adami H.O., Bergstrom R., Mohner M., Zatonski W., Storm H., Ekbom A., Tretli S., Teppo L., Ziegler H., Rahu M.et al. Testicular cancer in nine northern European countries. International Journal of Cancer. 59:1994;33-38.
2. Auger J., Kunstmann J.M., Czyglik F., Jouannet P. Decline in semen quality among fertile men in Paris during the past 20 years. New England Journal of Medicine. 332:1995;281-285.
3. Bergeron J.M., Crews D., McLachlan J.A. PCBs as environmental estrogens. turtle sex determination as a biomarker of environmental contamination Environmental Health Perspectives. 102:1994;780-781.
4. Bitman J., Cecil H.C. Estrogenic activity of DDT analogs and poly-chlorinated biphenyls. Journal of Agricultural and Food Chemistry. 18:1970;1108-1112.
5. Blaier R.B., Fang H., Branham W.S., Hass B.S., Dial S.L., Moland C.L., Tong W., Shi L., Perkins R., Sheehan D.M. The estrogen receptor relative binding affinities of 188 natural and xenochemicals. structural diversity of ligands Toxicological Sciences. 54:2000;138-153.
6. Boettger-Tong H., Murthy L., Chiappetta C., Kirkland J.L., Goodwin B., Adlercreutz H., Stancel G.M., Makela S.A. A case of laboratory animal feed with high estrogenic activity and its impact on in vivo responses to exogenously administered estrogens. Environmental Health Perspectives. 106:1998;369-373.
7. Bolger R., Wiese T.E., Ervin K., Nestich S., Checovich W. Rapid screening of environmental chemicals for estrogen receptor binding capacity. Environmental Health Perspectives. 106:1998;551-557.
8. Bromwich P., Cohen J., Stewart I., Walker A. Decline in sperm counts. an artefact of changed reference range of "normal"? British Medical Journal. 309:1994;19-22.
9. Bujan L., Mansat A., Pontonnier F., Mieusset R. Time series analysis of sperm concentration in fertile men in Toulouse, France between 1977 and 1992. British Medical Journal. 312:1996;471-472.
10. Colborn T., vom Saal F.S., Soto A.M. Developmental effects of endocrine-disrupting chemicals in wildlife and humans. Environmental Health Perspectives. 101:1993;378-384.
11. Coldham N.G., Dave M., Sivapathasundaram S., McDonnell D.P., Conner C., Sauer M.J. Evaluation of a recombinant yeast cell-estrogen screening assay. Environmental Health Perspectives. 105:1997;734-742.
12. Daston G.P., Gooch J.W., Breslin W.J., Shuey D.L., Nikiforov A.I., Fico T.A. Environmental estrogens and reproductive health. a discussion of human and environmental data Reproductive Toxicology. 11:1997;465-481.
13. Desjardins C. Morphological, physiological, and biochemical aspects of male reproduction. Dixon R.L. Reproductive Toxicology. 1985;131-146 Raven Press, New York.
14. Elder R.L. Final report on the safety assessment of methylparaben, ethylparaben, propyl paraben and butyl paraben. Journal of the American College of Toxicology. 3:1984;147-209.
15. Filler R. Methods for evaluation of rat epididymal sperm morphology. Chapin R.E., Heindel J.J. Male Reproductive Toxicology. 1993;334-343 Academic Press, San Diego.
16. Gad S.C., Weil C.S. Statistics for toxicologists. Hayes A.W. Principles and Methods of Toxicology, third ed. 1994;221-274 Raven Press, New York.
17. Ginsberg J. Environmental estrogens. Lancet. 343:1994;284-285.
18. Hart J.E. Endocrine pathology of estrogens. species differences Pharmacology and Therapeutics. 47:1990;203-218.
19. Herbert D.C., Supakar P.C., Roy A.K. Male reproduction. Witorsch R.J. Reproductive Toxicology, second ed. 1995;3-21 Raven Press, New York.
20. Heywood R., Wadsworth P.F. The experimental toxicology of estrogens. Pharmacology and Therapeutics. 8:1980;125-142.
21. Hossaiani A., Larsen R.-R., Larsen J.C. Lack of oestrogenic effects of food preservatives (parabens) in uterotrophic assays. Food and Chemical Toxicology. 38:2000;319-323.
22. Ishiwata H., Sugita T., Kawasaki Y., Takeda Y., Yamada T., Nishijima M., Fukusawa Y. Evaluation of preservatives concentrations in foods and their daily intake based on official inspection results in Japan in fiscal year 1996. Journal of the Food Hygienic Society of Japan. 40:1999;246-258.
23. Jonckheere A.R. A distribution-free k-sample test against ordered alternatives. Biometrika. 41:1954;133-145.
24. Jordan V.C., Liberman M.G. Estrogen stimulated prolactin synthesis in vitro. Classification of agonist, partial agonist, and antagonist actions based on structure. Molecular Pharmacology. 26:1984;279-285.
25. Kang K.-S., Che J.-H., Ryu D.-Y., Kim T.-W., Li G.-X., Lee Y.-S. Decreased sperm number and motile activity on the F1 offspring materally exposed to butyl p-hydroxybenzoic acid (butyl paraben). Journal of Veterinary Medicine and Science. 64:2002;227-235.
26. Korach K.S., Saver P., Chae K., McLachlan J.A., McKinney J.D. Estrogen receptor-binding activity of polychlorinated hydroxybiphenyls. conformationally restricted structural probes Molecular Pharmacology. 33:1987;120-126.
27. Lemini C., Silva G., Timossi C., Luque D., Valverde A., Gonzalez-Martinez M., Hernandez A., Rubio-Poo C., Chavez Lara B., Valenzuela F. Estrogenic effects of p-hydoroxybenzoic acid in CD1 mice. Environmental Research. 75:1997;130-134.
28. Matlai P., Beral V. Trends in congenital malformations of external genitalia. Lancet. 1:1985;108.
29. Matthews C., Davidson J., Bauer E., Morrison J.L., Richardson A.P. P-Hydroxybenzoic acid esters as preservatives II. Journal of the American Pharmaceutical Association. 45:1956;260-267.
30. Ministry of Health and Welfare, Japan The Japanese Standards for Food Additives, sixth ed (English version). 1994;Ministry of Health and Welfare, Tokyo.
31. Moller H. Trends in incidence of testicular cancer and prostate cancer in Denmark. Human Reproduction. 16:2001;1007-1011.
32. Nagel S.C., vom Saal F.S., Thayer K.A., Dhar M.G., Boechler M., Welshons W.V. Relative binding affinity-serum modified access (RBA-SMA) assay predicts the relative in vivo activity of xenoestrogens bisphenol A and octylphenol. Environmental Health Perspectives. 105:1997;70-76.
33. Nakai M., Tobira Y., Asai D., Yakabe Y., Shimizu T., Noguchi M., Takatsuki M., Shimohigashi Y. Binding characteristics of dialkyl phthalates for the estrogen receptor. Biochemical and Biophysical Research Communications. 254:1999;311-314.
34. Nimrod A.C., Benson W.H. Environmental estrogenic effects of alkyl-phenol ethoxylate. Critical Reviews in Toxicology. 26:1996;335-364.
35. Nishihara T., Nishikawa J. Bioassay for endocrine disruptors by using yeast two-hybrid system. Folia Pharmacologica Japonica. 118:2001;203-210. (in Japanese).
36. Nishihara T., Nishikawa J., Kanayama T., Dakeyama F., Saito K., Imagawa M., Takatori S., Kitagawa Y., Hori S., Utsumi H. Estrogenic activities of 517 chemicals by yeast two-hybrid assay. Journal of Health Sciences. 46:2000;282-298.
37. Odum J., Tinwell H., Jones K., van Miller J.P., Joiner R.L., Tobin G., Kawasaki H., Deghenghi R., Ashby J. Effect of rodent diets on the sexual development of the rat. Toxicological Sciences. 61:2001;115-127.
38. Oishi S. Effects of butyl paraben on the male reproductive system. Toxicology and Industrial Health. 17:2001;31-39.
39. Oishi S. Effects of butyl paraben on the male reproductive system in mice. Archives of Toxicology. 76:2002;423-429.
40. Oishi S., Hiraga K. Testicular atrophy induced by phthalic acid esters. effect on testosterone and zinc concentrations Toxicology and Applied Pharmacology. 53:1980;35-41.
41. Okubo T., Yokoyama Y., Kano K., Kano I. ER-dependent oestrogenic activity of parabens assessed by proliferation of human breast cancer MCF-7 cells and expression of ERα and PR. Food and Chemical Toxicology. 39:2001;1225-1232.
42. Olsen G.W., Bodner K.M., Ramlow J.M., Ross C.E., Lipshultz L.I. Have sperm counts been reduced 50 percent in 50 years? A statistical model revisited. Fertility and Sterility. 63:1995;887-893.
43. Pajarinen J., Laippala P., Penttila A., Karhunen P.J. Incidence of disorders of spermatogenesis in middle aged Finnish men, 1981-91. two necropsy series British Medical Journal. 314:1997;13-18.
44. Pedersen K.L., Pedersen S.N., Christiansen L.B., Korsgaard B., Bjerregaard P. The preservatives ethyl-, propyl- and butyl paraben are estrogenic in an in vivo fish assay. Pharmacology and Toxicology. 86:2000;110-113.
45. Rastogi S.C., Schouten A., De Kruijf N., Weijland J.W. Contents of methyl-, ethyl, propyl-, butyl- and benzylparaben in cosmetic products. Contact Dermatitis. 32:1995;28-30.
46. Reeves P.G., Nielsen F.H., Fahey G.C. Jr. AIN-93 purified diets for laboratory rodents: Final report of the American Institute of Nutrition ad hoc writing committee on the reformulation of the AIN-76 rodent diet. Journal of Nutrition. 123:1993;1939-1951.
47. Routledge E.J., Parker J., Odum J., Ashby J., Sumpter J.P. Some alkyl hydoroxybenzoate preservatives (parabens) are estrogenic. Toxicology and Applied Pharmacology. 153:1998;12-19.
48. Routledge E.J., Sumpter J.P. Structural features of alkylphenolic chemicals associated with estrogenic activity. Journal of Biological Chemistry. 272:1997;3280-3288.
49. SCF Report of the Scientific Committee for Food, 35th series. Food Science and Techniques. 1996;Scientific Committee for Food. European Commission, Directorate-General Industry, Brussels.
50. Satoh K., Nagai F., Oaki N., Nishijima M. Competitive binding of some alkyl p-hydroxybenzoates to human estrogen receptor α and β Yakugaku Zasshi. 120:2000;1429-1433. (in Japanese).
51. Sharpe R.M., Skakkebaek N.E. Are estrogens involved in falling sperm counts and disorders of the male reproductive tract? Lancet. 341:1993;1392-1395.
52. Song B.L., Li H.Y., Peng D.R. In vitro spermatocidal activity of parabens against human spermatozoa. Contraception. 39:1989;331-335.
53. Song B.L., Peng D.R., Li H.Y., Zhang G.H., Zhang J., Li K.L., Zhao Y.Q. Evaluation of the effect of butyl p-hydoroxybenzoate on the proteolytic activity and membrane function of human spermatozoa. Journal of Reproduction and Fertility. 91:1991;435-440.
54. Soni M.G., Burdock G.A., Taylor S.L., Greenberg N.A. Safety assessment of propyl paraben. a review of the published literature Food and Chemical Toxicology. 39:2001;513-532.
55. Suzuki I., Nojima S., Tanimura A. Commentary on Official Compendium of Food Additives of Japan, seventh ed., D-1063. 1999;Hirokawa Shoten Inc, Tokyo. (in Japanese).
56. Swan S.H., Elkin E.P., Fenster L. The question of declining sperm density revisited. an analysis of 101 studies published 1934-1996 Environmental Health Perspectives. 108:2000;961-966.
57. vom Saal F.S., Cooke P., Buchaman D.L., Palanza P.P., Thayer K.A., Nagel S.C., Parmigiani S., Welshons W.V. A physiologically based approach to the study of bisphenol A and other estrogenic chemicals on the size of reproductive organs, daily sperm production, and behaviour. Toxicity and Industrial Health. 14:1998;239-260.
58. Vierula M., Niemi M., Keiski A., Saaranen M., Saarikoski S., Suominen J. High and unchanged sperm counts of Finnish men. International Journal of Andrology. 19:1996;11-17.
59. White R., Jobling S., Hoare S.A., Sumpter J.P., Parker M.G. Environmentally persistent alkylphenolic compounds are estrogenic. Endocrinology. 135:1994;175-182.
60. Zacharewsky T.R., Meek M.D., Clemons J.H., Wu Z.F., Fieldin M.R., Mathews J.B. Examination of the in vitro and in vivo estrogenic activities of eight commercial phthalate esters. Toxicological Sciences. 46:1998;282-293.
61. Zar J.H. Biostatistical Analysis, fourth ed. 1999;Prentice Hall International, NJ.