-
1
-
-
0033624575
-
The common PPARγPro12 Ala polymorphism is associated with decreased risk of type 2 diabetes
-
Altshuler, D., Hirschorn, J.N., Klannemark, M., Lindgren, C.M., Vohl, M.-C., Nemesh, J., Lane, R.L., Schaffner, S.F., Bolk, S., Brewer, C. et al. (2000). The common PPARγPro12 Ala polymorphism is associated with decreased risk of type 2 diabetes. Nature Genet., 26, 76-80.
-
(2000)
Nature Genet.
, vol.26
, pp. 76-80
-
-
Altshuler, D.1
Hirschorn, J.N.2
Klannemark, M.3
Lindgren, C.M.4
Vohl, M.-C.5
Nemesh, J.6
Lane, R.L.7
Schaffner, S.F.8
Bolk, S.9
Brewer, C.10
-
2
-
-
0031589186
-
Chromosomal localization and partial genomic structure of the human peroxisome proliferator activated receptor-gamma (hPPAR gamma) gene
-
Beamer, B.A., Negri, C., Yen, C.J., Gavrilova, O., Rumberger, J.M., Durcan, M.J., Yarnall, D.P., Hawkins, A.L., Griffin, C.A., Burns, D.K. et al. (1997). Chromosomal localization and partial genomic structure of the human peroxisome proliferator activated receptor-gamma (hPPAR gamma) gene. Biochem. Biophys. Res. Commun., 233, 756-759.
-
(1997)
Biochem. Biophys. Res. Commun.
, vol.233
, pp. 756-759
-
-
Beamer, B.A.1
Negri, C.2
Yen, C.J.3
Gavrilova, O.4
Rumberger, J.M.5
Durcan, M.J.6
Yarnall, D.P.7
Hawkins, A.L.8
Griffin, C.A.9
Burns, D.K.10
-
3
-
-
0031667127
-
Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor-gamma2 gene with obesity in two Caucasian populations
-
Beamer, B., Yen, C., Andersen, R., Muller, D., Elahi, D., Cheskin, L., Andres, R., Roth, J. and Shuldiner, A.R. (1998) Association of the Pro12Ala variant in the peroxisome proliferator-activated receptor-gamma2 gene with obesity in two Caucasian populations. Diabetes, 47, 1806-1808.
-
(1998)
Diabetes
, vol.47
, pp. 1806-1808
-
-
Beamer, B.1
Yen, C.2
Andersen, R.3
Muller, D.4
Elahi, D.5
Cheskin, L.6
Andres, R.7
Roth, J.8
Shuldiner, A.R.9
-
4
-
-
0031595923
-
Pro12Ala substitution in PPAR gamma 2 is associated with decreased receptor activity, lower body mass index and improved insulin sensitivity
-
Deeb, S.S., Fajas, L., Nemoto, M., Pihlajamäki, J., Mykkänen, L., Kuusito, J., Laakso, M., Fujimoto, W. and Auwerx, J.A. (1998) Pro12Ala substitution in PPAR gamma 2 is associated with decreased receptor activity, lower body mass index and improved insulin sensitivity. Nature Genet., 20, 284-287.
-
(1998)
Nature Genet.
, vol.20
, pp. 284-287
-
-
Deeb, S.S.1
Fajas, L.2
Nemoto, M.3
Pihlajamäki, J.4
Mykkänen, L.5
Kuusito, J.6
Laakso, M.7
Fujimoto, W.8
Auwerx, J.A.9
-
5
-
-
0024437305
-
Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome
-
Dunaif, A., Segal, K.R., Futterweit, W. and Dobrjansky, A. (1989) Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome. Diabetes, 38, 1165-1174.
-
(1989)
Diabetes
, vol.38
, pp. 1165-1174
-
-
Dunaif, A.1
Segal, K.R.2
Futterweit, W.3
Dobrjansky, A.4
-
6
-
-
0029795871
-
The insulin-sensitizing agent troglitazone improves metabolic and reproductive abnormalities in the polycystic ovary syndrome
-
Dunaif, A., Scott, D., Finegood, D., Quintana, B. and Whitcomb, R. (1996) The insulin-sensitizing agent troglitazone improves metabolic and reproductive abnormalities in the polycystic ovary syndrome. J. Clin. Endocrinol. Metab., 81, 3299-3306.
-
(1996)
J. Clin. Endocrinol. Metab.
, vol.81
, pp. 3299-3306
-
-
Dunaif, A.1
Scott, D.2
Finegood, D.3
Quintana, B.4
Whitcomb, R.5
-
7
-
-
0030590074
-
Molecular cloning, expression and characterization of human peroxisome proliferator activated receptors gamma 1 and gamma 2
-
Elbrecht, A., Chen, Y., Cullinan, C.A., Hayes, N., Leibowitz, M., Moller, D.E. and Berger, J. (1996) Molecular cloning, expression and characterization of human peroxisome proliferator activated receptors gamma 1 and gamma 2. Biochem. Biophys. Res. Commun., 224, 431-437.
-
(1996)
Biochem. Biophys. Res. Commun.
, vol.224
, pp. 431-437
-
-
Elbrecht, A.1
Chen, Y.2
Cullinan, C.A.3
Hayes, N.4
Leibowitz, M.5
Moller, D.E.6
Berger, J.7
-
8
-
-
12644305063
-
Clinical assessment of body hair growth in women
-
Ferriman, D. and Gallwey, J.D. (1961) Clinical assessment of body hair growth in women. J. Clin. Endocrinol. Metab., 21, 1440-1447.
-
(1961)
J. Clin. Endocrinol. Metab.
, vol.21
, pp. 1440-1447
-
-
Ferriman, D.1
Gallwey, J.D.2
-
9
-
-
0034937378
-
Candidate genes in polycystic ovary syndrome
-
Franks, S., Gharani, N. and McCarthy, M. (2001) Candidate genes in polycystic ovary syndrome. Hum. Reprod. Update, 7, 405-410.
-
(2001)
Hum. Reprod. Update
, vol.7
, pp. 405-410
-
-
Franks, S.1
Gharani, N.2
McCarthy, M.3
-
10
-
-
0022625803
-
Persistence of insulin resistance in polycystic ovarian disease after inhibition of ovarian steroid secretion
-
Geffner, M.E., Kaplan, S.A., Berch, N., Golde, D.W., Landaw, E.M. and Chang, R.J. (1986) Persistence of insulin resistance in polycystic ovarian disease after inhibition of ovarian steroid secretion. Fertil. Steril. 45, 327-333.
-
(1986)
Fertil. Steril.
, vol.45
, pp. 327-333
-
-
Geffner, M.E.1
Kaplan, S.A.2
Berch, N.3
Golde, D.W.4
Landaw, E.M.5
Chang, R.J.6
-
11
-
-
0036170755
-
Insulin resistance is attenuated in women with polycystic ovary syndrome with the Pro(12)Ala polymorphism in the PPARgamma gene
-
Hara, M., Alcoser, S.Y., Qaadir, A., Beiswenger, K.K., Cox, N.J. and Ehrmann, D.A. (2002) Insulin resistance is attenuated in women with polycystic ovary syndrome with the Pro(12)Ala polymorphism in the PPARgamma gene. J. Clin. Endocrinol. Metab., 87, 772-775.
-
(2002)
J. Clin. Endocrinol. Metab.
, vol.87
, pp. 772-775
-
-
Hara, M.1
Alcoser, S.Y.2
Qaadir, A.3
Beiswenger, K.K.4
Cox, N.J.5
Ehrmann, D.A.6
-
12
-
-
0033626426
-
The PPARgamma 2 polymorphism pro12Ala is associated with better insulin sensitivity in the offspring of type 2 diabetic patients
-
Jacob, S., Stumvoll, M., Becker, R., Koch, M., Nielsen, M., Loblein, K., Maerker, E., Volk, A., Renn, W., Balletshofer, B. et al. (2000) The PPARgamma 2 polymorphism pro12Ala is associated with better insulin sensitivity in the offspring of type 2 diabetic patients. Horm. Metab. Res., 32, 413-416.
-
(2000)
Horm. Metab. Res.
, vol.32
, pp. 413-416
-
-
Jacob, S.1
Stumvoll, M.2
Becker, R.3
Koch, M.4
Nielsen, M.5
Loblein, K.6
Maerker, E.7
Volk, A.8
Renn, W.9
Balletshofer, B.10
-
13
-
-
0032948363
-
Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: A prospective, controlled study in 254 affected women
-
Legro, R.S., Kunselman, A.R., Dodson, W.C. and Dunaif, A. (1999) Prevalence and predictors of risk for type 2 diabetes mellitus and impaired glucose tolerance in polycystic ovary syndrome: A prospective, controlled study in 254 affected women. J. Clin. Endocrinol. Metab., 84, 165-169.
-
(1999)
J. Clin. Endocrinol. Metab.
, vol.84
, pp. 165-169
-
-
Legro, R.S.1
Kunselman, A.R.2
Dodson, W.C.3
Dunaif, A.4
-
14
-
-
0033973843
-
Improved insulin-sensitivity in mice heterozygous for PPAR-gamma deficiency
-
Miles, P.D., Barak, Y., He, W., Evans, R.M. and Olefsky, J.M. (2000) Improved insulin-sensitivity in mice heterozygous for PPAR-gamma deficiency. J. Clin. Invest., 105, 287-292.
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 287-292
-
-
Miles, P.D.1
Barak, Y.2
He, W.3
Evans, R.M.4
Olefsky, J.M.5
-
15
-
-
0034119173
-
Insulin sensitivity, insulin secretion, and metabolic and hormonal parameters in healthy women and women with polycystic ovarian syndrome
-
Morin-Papunen, L.C., Vauhkonen, I., Koivunen, R.M., Roukonen, A. and Tapanainen, J.S. (2000) Insulin sensitivity, insulin secretion, and metabolic and hormonal parameters in healthy women and women with polycystic ovarian syndrome. Hum. Reprod., 15, 1266-1274.
-
(2000)
Hum. Reprod.
, vol.15
, pp. 1266-1274
-
-
Morin-Papunen, L.C.1
Vauhkonen, I.2
Koivunen, R.M.3
Roukonen, A.4
Tapanainen, J.S.5
-
16
-
-
0034685629
-
Insulin sensitizer, troglitazone, directly inhibits aromatase activity in human ovarian granulosa cells
-
Mu, Y.M., Yanase, T., Nishi, Y., Waseda, N., Oda, T., Tanaka, A., Takayanagi, R. and Nawata, H. (2000) Insulin sensitizer, troglitazone, directly inhibits aromatase activity in human ovarian granulosa cells. Biochem. Biophys. Res. Commun., 271, 710-713.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.271
, pp. 710-713
-
-
Mu, Y.M.1
Yanase, T.2
Nishi, Y.3
Waseda, N.4
Oda, T.5
Tanaka, A.6
Takayanagi, R.7
Nawata, H.8
-
17
-
-
0035811516
-
Combined treatment with specific ligands for PPARgamma: RXR nuclear receptor system markedly inhibits the expression of cytochrome P450arom in human granulosa cancer cells
-
Mu, Y.M., Yanase, T., Nishi, Y., Takayanagi, R., Goto, K. and Nawata, H. (2001) Combined treatment with specific ligands for PPARgamma: RXR nuclear receptor system markedly inhibits the expression of cytochrome P450arom in human granulosa cancer cells. Mol. Cell. Endocrinol., 181, 239-248.
-
(2001)
Mol. Cell. Endocrinol.
, vol.181
, pp. 239-248
-
-
Mu, Y.M.1
Yanase, T.2
Nishi, Y.3
Takayanagi, R.4
Goto, K.5
Nawata, H.6
-
18
-
-
0024381472
-
Suppression of serum insulin by diazoxide reduces serum testosterone levels in obese women with polycystic ovary syndrome
-
Nestler, J.E., Barlascini, C.O., Matt, D.W., Steingold, K.A., Plymate, S.R., Clore, J.N. and Blackard, W.G. (1989) Suppression of serum insulin by diazoxide reduces serum testosterone levels in obese women with polycystic ovary syndrome. J. Clin. Endocrinol. Metab., 68, 1027-1032.
-
(1989)
J. Clin. Endocrinol. Metab.
, vol.68
, pp. 1027-1032
-
-
Nestler, J.E.1
Barlascini, C.O.2
Matt, D.W.3
Steingold, K.A.4
Plymate, S.R.5
Clore, J.N.6
Blackard, W.G.7
-
19
-
-
0032869123
-
Molecular genetics of the Finnish disease heritage
-
Peltonen, L., Jalanko, A. and Varilo, T. (1999) Molecular genetics of the Finnish disease heritage. Hum. Mol. Genet., 8, 1913-1923.
-
(1999)
Hum. Mol. Genet.
, vol.8
, pp. 1913-1923
-
-
Peltonen, L.1
Jalanko, A.2
Varilo, T.3
-
20
-
-
0033624612
-
The Pro12Ala substitution in the peroxisome proliferator activated receptor gamma 2 is associated with an insulin-sensitive phenotype in families with familial combined hyperlipidemia and in nondiabetic elderly subjects with dyslipidemia
-
Pihlajamäki, J., Miettinen, R., Valve, R., Karjalainen, L., Mykkänen, L., Kuusisto, J., Deeb, S., Auwerx, J. and Laakso, M. (2000) The Pro12Ala substitution in the peroxisome proliferator activated receptor gamma 2 is associated with an insulin-sensitive phenotype in families with familial combined hyperlipidemia and in nondiabetic elderly subjects with dyslipidemia. Atherosclerosis, 151, 567-574.
-
(2000)
Atherosclerosis
, vol.151
, pp. 567-574
-
-
Pihlajamäki, J.1
Miettinen, R.2
Valve, R.3
Karjalainen, L.4
Mykkänen, L.5
Kuusisto, J.6
Deeb, S.7
Auwerx, J.8
Laakso, M.9
-
21
-
-
0034745183
-
Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma 2 gene is associated with increased antilipolytic insulin sensitivity
-
Stumvoll, M., Wahl, H.G., Loblein, K., Becker, R., Machicao, F., Jacob, S. and Haring, H. (2001) Pro12Ala polymorphism in the peroxisome proliferator-activated receptor-gamma 2 gene is associated with increased antilipolytic insulin sensitivity. Diabetes, 50, 576-881.
-
(2001)
Diabetes
, vol.50
, pp. 576-881
-
-
Stumvoll, M.1
Wahl, H.G.2
Loblein, K.3
Becker, R.4
Machicao, F.5
Jacob, S.6
Haring, H.7
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