Effects of lactone derivatives on aromatase (CYP19) activity in H295R human adrenocortical and (anti)androgenicity in transfected LNCaP human prostate cancer cells

European Journal of Pharmacology

Volumn 593, Issue 1-3, 2008, Pages 92-98

  Sanderson, Thomas ^a   Renaud, Martin ^a   Scholten, Deborah ^b   Nijmeijer, Sandra ^b   van den Berg, Martin ^b   Cowell, Simon ^c   Guns, Emma ^c   Nelson, Colleen ^c   Mutarapat, Thumnoon ^d   Ruchirawat, Somsak ^d  

^a INRS INSTITUT ARMAND FRAPPIER   (Canada)

^b UTRECHT UNIVERSITY   (Netherlands)

^c VANCOUVER GENERAL HOSPITAL   (Canada)

^d Toxicology and Management of Chemicals   (Thailand)

Author keywords

Anti androgens; Aromatase; H295R; Hormone dependent cancer; Lactones; LNCaP

Indexed keywords

3 (3,4 DIMETHOXY PHENYL) 4 (3,4,5 TRIMETHOXY PHENYL) 5H FURAN 2 ONE; 3 (3,4 DIMETHOXY PHENYL) 4 (4 METHOXY PHENYL) 5H FURAN 2 ONE; 3,4 BIS (3,4 DIMETHOXY PHENYL) 4 (4 METHOXY PHENYL) 5H FURAN 2 ONE; ANDROGEN RECEPTOR; AROMATASE; FURAN DERIVATIVE; LACTONE DERIVATIVE;

ARTICLE; CANCER CELL; CONTROLLED STUDY; ENZYME ACTIVITY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN EXPRESSION; TUMOR GROWTH;

ADRENAL CORTEX NEOPLASMS; ANDROGENS; AROMATASE INHIBITORS; CELL LINE, TUMOR; CYCLIC AMP; DATA INTERPRETATION, STATISTICAL; GENES, REPORTER; HUMANS; LACTONES; LUCIFERASES; MALE; PROSTATIC NEOPLASMS; RECEPTORS, ANDROGEN; RNA, NEOPLASM; TETRAZOLIUM SALTS; THIAZOLES; TRANSFECTION;

EID: 49749084324     PISSN: 00142999     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejphar.2008.06.085     Document Type: Article

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