2,3,7,8-Tetrachlorodibenzo-p-dioxin and diindolymethanes differentially induce cytochrome P450 1A1, 1B1, and 19 in H295R human adrenocortical carcinoma cells

Toxicological Sciences

Volumn 61, Issue 1, 2001, Pages 40-48

  Sanderson, J Thomas ^a   Slobbe, Lennert ^a   Lansbergen, Gideon W A ^a   Safe, Stephen ^b   Van Den Berg, Martin ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

^b TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Aromatase; CYP19; CYP1A1; CYP1B1; Diindolymethane; TCDD

Indexed keywords

2,3,7,8 TETRACHLORODIBENZO PARA DIOXIN; 3 INDOLEMETHANOL; ACID; ANDROSTENEDIONE; AROMATASE; AROMATIC HYDROCARBON RECEPTOR; CARBON; CARCINOGEN; CYTOCHROME P450 1A1; CYTOCHROME P450 1B1; DIINDOLYLMETHANE; DIMETHYL SULFOXIDE; DRUG ANALOG; ESTROGEN; ESTROGEN RECEPTOR; ESTRONE; ETHOXYRESORUFIN DEETHYLASE; INDOLE DERIVATIVE; MESSENGER RNA; METHANE; UNCLASSIFIED DRUG;

ADRENAL CORTEX CARCINOMA; ARTICLE; BREAST TUMOR; CARCINOMA CELL; CATALYSIS; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOTOXICITY; DRUG STRUCTURE; ENZYME ACTIVITY; ESTROGEN METABOLISM; ESTROGEN SYNTHESIS; EXPOSURE; HUMAN; HUMAN CELL; NUCLEOTIDE SEQUENCE; POLYMERIZATION; RODENT; STOMACH; TOXICITY TESTING; TUMOR GROWTH; VEGETABLE;

ADRENAL CORTEX; ADRENOCORTICAL CARCINOMA; AROMATASE; AROMATASE INHIBITORS; ARYL HYDROCARBON HYDROXYLASES; CELL LINE; CELL SURVIVAL; CYTOCHROME P-450 CYP1A1; CYTOCHROME P-450 ENZYME SYSTEM; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INDUCTION; FORMAZANS; HUMANS; INDOLES; IODINE RADIOISOTOPES; RADIOIMMUNOASSAY; RECEPTORS, ARYL HYDROCARBON; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; STRUCTURE-ACTIVITY RELATIONSHIP; TETRACHLORODIBENZODIOXIN; TETRAZOLIUM SALTS; TRITIUM; TUMOR CELLS, CULTURED;

RODENTIA;

EID: 0035036028     PISSN: 10966080     EISSN: None     Source Type: Journal    
DOI: 10.1093/toxsci/61.1.40     Document Type: Article

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