-
1
-
-
0013907774
-
Werner's syndrome a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process
-
Epstein C.J., Martin G.M., Schultz A.L., and Motulsky A.G. Werner's syndrome a review of its symptomatology, natural history, pathologic features, genetics and relationship to the natural aging process. Medicine (Baltimore) 45 (1966) 177-221
-
(1966)
Medicine (Baltimore)
, vol.45
, pp. 177-221
-
-
Epstein, C.J.1
Martin, G.M.2
Schultz, A.L.3
Motulsky, A.G.4
-
3
-
-
0016678691
-
Variegated translocation mosaicism in human skin fibroblast cultures
-
Hoehn H., Bryant E.M., Au K., Norwood T.H., Boman H., and Martin G.M. Variegated translocation mosaicism in human skin fibroblast cultures. Cytogenet. Cell Genet. 15 (1975) 282-298
-
(1975)
Cytogenet. Cell Genet.
, vol.15
, pp. 282-298
-
-
Hoehn, H.1
Bryant, E.M.2
Au, K.3
Norwood, T.H.4
Boman, H.5
Martin, G.M.6
-
4
-
-
0019440557
-
Cytogenetics of Werner's syndrome cultured skin fibroblasts: variegated translocation mosaicism
-
Salk D., Au K., Hoehn H., and Martin G.M. Cytogenetics of Werner's syndrome cultured skin fibroblasts: variegated translocation mosaicism. Cytogenet. Cell Genet. 30 (1981) 92-107
-
(1981)
Cytogenet. Cell Genet.
, vol.30
, pp. 92-107
-
-
Salk, D.1
Au, K.2
Hoehn, H.3
Martin, G.M.4
-
5
-
-
0024465870
-
Mutator phenotype of Werner syndrome is characterized by extensive deletions
-
Fukuchi K., Martin G.M., and Monnat Jr. R.J. Mutator phenotype of Werner syndrome is characterized by extensive deletions. Proc. Natl. Acad. Sci. U.S.A. 86 (1989) 5893-5897
-
(1989)
Proc. Natl. Acad. Sci. U.S.A.
, vol.86
, pp. 5893-5897
-
-
Fukuchi, K.1
Martin, G.M.2
Monnat Jr., R.J.3
-
6
-
-
0025169778
-
Increased frequency of 6-thioguanine-resistant peripheral blood lymphocytes in Werner syndrome patients
-
Fukuchi K., Tanaka K., Kumahara Y., Marumo K., Pride M.B., Martin G.M., and Monnat Jr. R.J. Increased frequency of 6-thioguanine-resistant peripheral blood lymphocytes in Werner syndrome patients. Hum. Genet. 84 (1990) 249-252
-
(1990)
Hum. Genet.
, vol.84
, pp. 249-252
-
-
Fukuchi, K.1
Tanaka, K.2
Kumahara, Y.3
Marumo, K.4
Pride, M.B.5
Martin, G.M.6
Monnat Jr., R.J.7
-
7
-
-
0023712434
-
Spontaneous and induced chromosomal instability in Werner syndrome
-
Gebhart E., Bauer R., Raub U., Schinzel M., Ruprecht K.W., and Jonas J.B. Spontaneous and induced chromosomal instability in Werner syndrome. Hum. Genet. 80 (1988) 135-139
-
(1988)
Hum. Genet.
, vol.80
, pp. 135-139
-
-
Gebhart, E.1
Bauer, R.2
Raub, U.3
Schinzel, M.4
Ruprecht, K.W.5
Jonas, J.B.6
-
8
-
-
0031453968
-
An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants
-
Ogburn C.E., Oshima J., Poot M., Chen R., Hunt K.E., Gollahon K.A., Rabinovitch P.S., and Martin G.M. An apoptosis-inducing genotoxin differentiates heterozygotic carriers for Werner helicase mutations from wild-type and homozygous mutants. Hum. Genet. 101 (1997) 121-125
-
(1997)
Hum. Genet.
, vol.101
, pp. 121-125
-
-
Ogburn, C.E.1
Oshima, J.2
Poot, M.3
Chen, R.4
Hunt, K.E.5
Gollahon, K.A.6
Rabinovitch, P.S.7
Martin, G.M.8
-
9
-
-
0033866655
-
Spontaneous and X-ray-induced chromosomal aberrations in Werner syndrome cells detected by FISH using chromosome-specific painting probes
-
Grigorova M., Balajee A.S., and Natarajan A.T. Spontaneous and X-ray-induced chromosomal aberrations in Werner syndrome cells detected by FISH using chromosome-specific painting probes. Mutagenesis 15 (2000) 303-310
-
(2000)
Mutagenesis
, vol.15
, pp. 303-310
-
-
Grigorova, M.1
Balajee, A.S.2
Natarajan, A.T.3
-
10
-
-
33144469989
-
Exogenous expression of exonuclease domain-deleted WRN interferes with the repair of radiation-induced DNA damages
-
Kashino G., Kodama S., Suzuki K., Matsumoto T., and Watanabe M. Exogenous expression of exonuclease domain-deleted WRN interferes with the repair of radiation-induced DNA damages. J. Radiat. Res. (Tokyo) 46 (2005) 407-414
-
(2005)
J. Radiat. Res. (Tokyo)
, vol.46
, pp. 407-414
-
-
Kashino, G.1
Kodama, S.2
Suzuki, K.3
Matsumoto, T.4
Watanabe, M.5
-
11
-
-
2342569002
-
-
A. Blank, M.S. Bobola, B. Gold, S. Varadarajan, D.K. D, E.H. Meade, P.S. Rabinovitch, L.A. Loeb, J.R. Silber, The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: implications for WRN function, DNA Repair (Amst) 3 (2004) 629-638.
-
A. Blank, M.S. Bobola, B. Gold, S. Varadarajan, D.K. D, E.H. Meade, P.S. Rabinovitch, L.A. Loeb, J.R. Silber, The Werner syndrome protein confers resistance to the DNA lesions N3-methyladenine and O6-methylguanine: implications for WRN function, DNA Repair (Amst) 3 (2004) 629-638.
-
-
-
-
12
-
-
32644449296
-
The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase beta
-
Harrigan J.A., Wilson III D.M., Prasad R., Opresko P.L., Beck G., May A., Wilson S.H., and Bohr V.A. The Werner syndrome protein operates in base excision repair and cooperates with DNA polymerase beta. Nucleic Acids Res. 34 (2006) 745-754
-
(2006)
Nucleic Acids Res.
, vol.34
, pp. 745-754
-
-
Harrigan, J.A.1
Wilson III, D.M.2
Prasad, R.3
Opresko, P.L.4
Beck, G.5
May, A.6
Wilson, S.H.7
Bohr, V.A.8
-
13
-
-
0036581178
-
Werner syndrome diploid fibroblasts are sensitive to 4-nitroquinoline-N-oxide and 8-methoxypsoralen: implications for the disease phenotype
-
Poot M., Gollahon K.A., Emond M.J., Silber J.R., and Rabinovitch P.S. Werner syndrome diploid fibroblasts are sensitive to 4-nitroquinoline-N-oxide and 8-methoxypsoralen: implications for the disease phenotype. FASEB J. 16 (2002) 757-758
-
(2002)
FASEB J.
, vol.16
, pp. 757-758
-
-
Poot, M.1
Gollahon, K.A.2
Emond, M.J.3
Silber, J.R.4
Rabinovitch, P.S.5
-
14
-
-
28844509443
-
The Pso4 mRNA splicing and DNA repair complex interacts with WRN for processing of DNA interstrand cross-links
-
Zhang N., Kaur R., Lu X., Shen X., Li L., and Legerski R.J. The Pso4 mRNA splicing and DNA repair complex interacts with WRN for processing of DNA interstrand cross-links. J. Biol. Chem. 280 (2005) 40559-40567
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 40559-40567
-
-
Zhang, N.1
Kaur, R.2
Lu, X.3
Shen, X.4
Li, L.5
Legerski, R.J.6
-
15
-
-
0032573157
-
A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity
-
Lebel M., and Leder P. A deletion within the murine Werner syndrome helicase induces sensitivity to inhibitors of topoisomerase and loss of cellular proliferative capacity. Proc. Natl. Acad. Sci. U.S.A. 95 (1998) 13097-13102
-
(1998)
Proc. Natl. Acad. Sci. U.S.A.
, vol.95
, pp. 13097-13102
-
-
Lebel, M.1
Leder, P.2
-
16
-
-
0035169035
-
Werner's syndrome protein is required for correct recovery after replication arrest and DNA damage induced in S-phase of cell cycle
-
Pichierri P., Franchitto A., Mosesso P., and Palitti F. Werner's syndrome protein is required for correct recovery after replication arrest and DNA damage induced in S-phase of cell cycle. Mol. Biol. Cell 12 (2001) 2412-2421
-
(2001)
Mol. Biol. Cell
, vol.12
, pp. 2412-2421
-
-
Pichierri, P.1
Franchitto, A.2
Mosesso, P.3
Palitti, F.4
-
17
-
-
0037364415
-
RecQ helicases: caretakers of the genome
-
Hickson I.D. RecQ helicases: caretakers of the genome. Nat. Rev. Cancer 3 (2003) 169-178
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 169-178
-
-
Hickson, I.D.1
-
18
-
-
33748744378
-
Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability
-
Sharma S., Doherty K.M., and Brosh Jr. R.M. Mechanisms of RecQ helicases in pathways of DNA metabolism and maintenance of genomic stability. Biochem. J. 398 (2006) 319-337
-
(2006)
Biochem. J.
, vol.398
, pp. 319-337
-
-
Sharma, S.1
Doherty, K.M.2
Brosh Jr., R.M.3
-
19
-
-
0030751354
-
The Werner syndrome protein is a DNA helicase
-
Gray M.D., Shen J.C., Kamath-Loeb A.S., Blank A., Sopher B.L., Martin G.M., Oshima J., and Loeb L.A. The Werner syndrome protein is a DNA helicase. Nat. Genet. 17 (1997) 100-103
-
(1997)
Nat. Genet.
, vol.17
, pp. 100-103
-
-
Gray, M.D.1
Shen, J.C.2
Kamath-Loeb, A.S.3
Blank, A.4
Sopher, B.L.5
Martin, G.M.6
Oshima, J.7
Loeb, L.A.8
-
20
-
-
0032545515
-
Werner syndrome protein. I. DNA helicase and dna exonuclease reside on the same polypeptide
-
Shen J.C., Gray M.D., Oshima J., Kamath-Loeb A.S., Fry M., and Loeb L.A. Werner syndrome protein. I. DNA helicase and dna exonuclease reside on the same polypeptide. J. Biol. Chem. 273 (1998) 34139-34144
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 34139-34144
-
-
Shen, J.C.1
Gray, M.D.2
Oshima, J.3
Kamath-Loeb, A.S.4
Fry, M.5
Loeb, L.A.6
-
22
-
-
38049075962
-
Human premature aging, DNA repair and RecQ helicases
-
Brosh Jr. R.M., and Bohr V.A. Human premature aging, DNA repair and RecQ helicases. Nucleic Acids Res. 35 (2007) 7527-7544
-
(2007)
Nucleic Acids Res.
, vol.35
, pp. 7527-7544
-
-
Brosh Jr., R.M.1
Bohr, V.A.2
-
23
-
-
31044435620
-
Multiple involvement of oxidative stress in Werner syndrome phenotype
-
Pagano G., Zatterale A., Degan P., d'Ischia M., Kelly F.J., Pallardo F.V., and Kodama S. Multiple involvement of oxidative stress in Werner syndrome phenotype. Biogerontology 6 (2005) 233-243
-
(2005)
Biogerontology
, vol.6
, pp. 233-243
-
-
Pagano, G.1
Zatterale, A.2
Degan, P.3
d'Ischia, M.4
Kelly, F.J.5
Pallardo, F.V.6
Kodama, S.7
-
24
-
-
21044447217
-
In vivo prooxidant state in Werner syndrome (WS): results from three WS patients and two WS heterozygotes
-
Pagano G., Zatterale A., Degan P., d'Ischia M., Kelly F.J., Pallardo F.V., Calzone R., Castello G., Dunster C., Giudice A., Kilinc Y., Lloret A., Manini P., Masella R., Vuttariello E., and Warnau M. In vivo prooxidant state in Werner syndrome (WS): results from three WS patients and two WS heterozygotes. Free Radic. Res. 39 (2005) 529-533
-
(2005)
Free Radic. Res.
, vol.39
, pp. 529-533
-
-
Pagano, G.1
Zatterale, A.2
Degan, P.3
d'Ischia, M.4
Kelly, F.J.5
Pallardo, F.V.6
Calzone, R.7
Castello, G.8
Dunster, C.9
Giudice, A.10
Kilinc, Y.11
Lloret, A.12
Manini, P.13
Masella, R.14
Vuttariello, E.15
Warnau, M.16
-
25
-
-
49649097118
-
Increased insulin, triglycerides, reactive oxygen species, and cardiac fibrosis in mice with a mutation in the helicase domain of the Werner syndrome gene homologue
-
Massip L., Garand C., Turaga R.V., Deschenes F., Thorin E., and Lebel M. Increased insulin, triglycerides, reactive oxygen species, and cardiac fibrosis in mice with a mutation in the helicase domain of the Werner syndrome gene homologue. Exp. Gerontol. (2005)
-
(2005)
Exp. Gerontol.
-
-
Massip, L.1
Garand, C.2
Turaga, R.V.3
Deschenes, F.4
Thorin, E.5
Lebel, M.6
-
26
-
-
27944477757
-
Werner protein protects nonproliferating cells from oxidative DNA damage
-
Szekely A.M., Bleichert F., Numann A., Van Komen S., Manasanch E., Ben Nasr A., Canaan A., and Weissman S.M. Werner protein protects nonproliferating cells from oxidative DNA damage. Mol. Cell Biol. 25 (2005) 10492-10506
-
(2005)
Mol. Cell Biol.
, vol.25
, pp. 10492-10506
-
-
Szekely, A.M.1
Bleichert, F.2
Numann, A.3
Van Komen, S.4
Manasanch, E.5
Ben Nasr, A.6
Canaan, A.7
Weissman, S.M.8
-
27
-
-
0020444895
-
Mechanism of action, metabolism, and toxicity of buthionine sulfoximine and its higher homologs, potent inhibitors of glutathione synthesis
-
Griffith O.W. Mechanism of action, metabolism, and toxicity of buthionine sulfoximine and its higher homologs, potent inhibitors of glutathione synthesis. J. Biol. Chem. 257 (1982) 13704-13712
-
(1982)
J. Biol. Chem.
, vol.257
, pp. 13704-13712
-
-
Griffith, O.W.1
-
28
-
-
1542376929
-
Glutathione metabolism and its implications for health
-
Wu G., Fang Y.Z., Yang S., Lupton J.R., and Turner N.D. Glutathione metabolism and its implications for health. J. Nutr. 134 (2004) 489-492
-
(2004)
J. Nutr.
, vol.134
, pp. 489-492
-
-
Wu, G.1
Fang, Y.Z.2
Yang, S.3
Lupton, J.R.4
Turner, N.D.5
-
29
-
-
31544467567
-
Glutathione depletion by buthionine sulfoximine induces DNA deletions in mice
-
Reliene R., and Schiestl R.H. Glutathione depletion by buthionine sulfoximine induces DNA deletions in mice. Carcinogenesis 27 (2006) 240-244
-
(2006)
Carcinogenesis
, vol.27
, pp. 240-244
-
-
Reliene, R.1
Schiestl, R.H.2
-
30
-
-
0027319211
-
Potent intracellular oxidative stress exerted by the carcinogen 4-nitroquinoline-N-oxide
-
Nunoshiba T., and Demple B. Potent intracellular oxidative stress exerted by the carcinogen 4-nitroquinoline-N-oxide. Cancer Res. 53 (1993) 3250-3252
-
(1993)
Cancer Res.
, vol.53
, pp. 3250-3252
-
-
Nunoshiba, T.1
Demple, B.2
-
31
-
-
0027249171
-
Site-specific DNA damage and 8-hydroxydeoxyguanosine formation by hydroxylamine and 4-hydroxyaminoquinoline 1-oxide in the presence of Cu(II): role of active oxygen species
-
Yamamoto K., Inoue S., and Kawanishi S. Site-specific DNA damage and 8-hydroxydeoxyguanosine formation by hydroxylamine and 4-hydroxyaminoquinoline 1-oxide in the presence of Cu(II): role of active oxygen species. Carcinogenesis 14 (1993) 1397-1401
-
(1993)
Carcinogenesis
, vol.14
, pp. 1397-1401
-
-
Yamamoto, K.1
Inoue, S.2
Kawanishi, S.3
-
32
-
-
0034632252
-
Validation of single cell gel assay in human leukocytes with 18 reference compounds
-
Frenzilli G., Bosco E., and Barale R. Validation of single cell gel assay in human leukocytes with 18 reference compounds. Mutat. Res. 468 (2000) 93-108
-
(2000)
Mutat. Res.
, vol.468
, pp. 93-108
-
-
Frenzilli, G.1
Bosco, E.2
Barale, R.3
-
33
-
-
5644229766
-
Marques Genomic instability in non-neoplastic oral mucosa cells can predict risk during 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis
-
Ribeiro D.A., Favero Salvadori D.M., da Silva R.N., Ribeiro Darros B., and Alencar M.E. Marques Genomic instability in non-neoplastic oral mucosa cells can predict risk during 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis. Oral Oncol. 40 (2004) 910-915
-
(2004)
Oral Oncol.
, vol.40
, pp. 910-915
-
-
Ribeiro, D.A.1
Favero Salvadori, D.M.2
da Silva, R.N.3
Ribeiro Darros, B.4
Alencar, M.E.5
-
34
-
-
0017202580
-
Main binding sites of the carcinogen, 4-nitroquinoline 1-oxide in nucleic acids
-
Tada M. Main binding sites of the carcinogen, 4-nitroquinoline 1-oxide in nucleic acids. Biochim. Biophys. Acta 454 (1976) 558-566
-
(1976)
Biochim. Biophys. Acta
, vol.454
, pp. 558-566
-
-
Tada, M.1
-
35
-
-
0033978881
-
Cellular Werner phenotypes in mice expressing a putative dominant-negative human WRN gene
-
Wang L., Ogburn C.E., Ware C.B., Ladiges W.C., Youssoufian H., Martin G.M., and Oshima J. Cellular Werner phenotypes in mice expressing a putative dominant-negative human WRN gene. Genetics 154 (2000) 357-362
-
(2000)
Genetics
, vol.154
, pp. 357-362
-
-
Wang, L.1
Ogburn, C.E.2
Ware, C.B.3
Ladiges, W.C.4
Youssoufian, H.5
Martin, G.M.6
Oshima, J.7
-
36
-
-
0032101153
-
Effect of age and apoptosis on the mouse homologue of the huWRN gene
-
Wu J., He J., and Mountz J.D. Effect of age and apoptosis on the mouse homologue of the huWRN gene. Mech. Ageing Dev. 103 (1998) 27-44
-
(1998)
Mech. Ageing Dev.
, vol.103
, pp. 27-44
-
-
Wu, J.1
He, J.2
Mountz, J.D.3
-
38
-
-
1542714327
-
In vivo DNA deletion assay to detect environmental and genetic predisposition to cancer
-
Reliene R., Bishop A.J., Aubrecht J., and Schiestl R.H. In vivo DNA deletion assay to detect environmental and genetic predisposition to cancer. Methods Mol. Biol. 262 (2004) 125-139
-
(2004)
Methods Mol. Biol.
, vol.262
, pp. 125-139
-
-
Reliene, R.1
Bishop, A.J.2
Aubrecht, J.3
Schiestl, R.H.4
-
39
-
-
0036200960
-
Increased frequency of DNA deletions in pink-eyed unstable mice carrying a mutation in the Werner syndrome gene homologue
-
Lebel M. Increased frequency of DNA deletions in pink-eyed unstable mice carrying a mutation in the Werner syndrome gene homologue. Carcinogenesis 23 (2002) 213-216
-
(2002)
Carcinogenesis
, vol.23
, pp. 213-216
-
-
Lebel, M.1
-
40
-
-
0031931010
-
Mutations in microphthalmia, the mouse homolog of the human deafness gene MITF, affect neuroepithelial and neural crest-derived melanocytes differently
-
Nakayama A., Nguyen M.T., Chen C.C., Opdecamp K., Hodgkinson C.A., and Arnheiter H. Mutations in microphthalmia, the mouse homolog of the human deafness gene MITF, affect neuroepithelial and neural crest-derived melanocytes differently. Mech. Dev. 70 (1998) 155-166
-
(1998)
Mech. Dev.
, vol.70
, pp. 155-166
-
-
Nakayama, A.1
Nguyen, M.T.2
Chen, C.C.3
Opdecamp, K.4
Hodgkinson, C.A.5
Arnheiter, H.6
-
41
-
-
0026568885
-
Radioautographic study on DNA synthesis of the retina and retinal pigment epithelium of developing mouse embryos
-
Kong Y., Usuda N., and Nagata T. Radioautographic study on DNA synthesis of the retina and retinal pigment epithelium of developing mouse embryos. Cell Mol. Biol. 38 (1992) 263-272
-
(1992)
Cell Mol. Biol.
, vol.38
, pp. 263-272
-
-
Kong, Y.1
Usuda, N.2
Nagata, T.3
-
42
-
-
0022374850
-
Effects of the long-term depletion of reduced glutathione in mice administered L-buthionine-S,R-sulfoximine
-
Sun J.D., Ragsdale S.S., Benson J.M., and Henderson R.F. Effects of the long-term depletion of reduced glutathione in mice administered L-buthionine-S,R-sulfoximine. Fundam. Appl. Toxicol. 5 (1985) 913-919
-
(1985)
Fundam. Appl. Toxicol.
, vol.5
, pp. 913-919
-
-
Sun, J.D.1
Ragsdale, S.S.2
Benson, J.M.3
Henderson, R.F.4
-
43
-
-
0016302964
-
Tumor induction in the progeny of mice receiving 4-nitroquinoline 1-oxide and N-methyl-N-nitrosourethan during pregnancy or lactation
-
Nomura T., Okamoto E., Tateishi N., Kimura S., and Isa Y. Tumor induction in the progeny of mice receiving 4-nitroquinoline 1-oxide and N-methyl-N-nitrosourethan during pregnancy or lactation. Cancer Res. 34 (1974) 3373-3378
-
(1974)
Cancer Res.
, vol.34
, pp. 3373-3378
-
-
Nomura, T.1
Okamoto, E.2
Tateishi, N.3
Kimura, S.4
Isa, Y.5
-
44
-
-
0034694955
-
Benzo(a)pyrene and X-rays induce reversions of the pink-eyed unstable mutation in the retinal pigment epithelium of mice
-
Bishop A.J., Kosaras B., Sidman R.L., and Schiestl R.H. Benzo(a)pyrene and X-rays induce reversions of the pink-eyed unstable mutation in the retinal pigment epithelium of mice. Mutat. Res. 457 (2000) 31-40
-
(2000)
Mutat. Res.
, vol.457
, pp. 31-40
-
-
Bishop, A.J.1
Kosaras, B.2
Sidman, R.L.3
Schiestl, R.H.4
-
45
-
-
33847618300
-
Enhanced levels of glutathione and protein glutathiolation in rat tongue epithelium during 4-NQO-induced carcinogenesis
-
Huang Z., Komninou D., Kleinman W., Pinto J.T., Gilhooly E.M., Calcagnotto A., and Richie Jr. J.P. Enhanced levels of glutathione and protein glutathiolation in rat tongue epithelium during 4-NQO-induced carcinogenesis. Int. J. Cancer 120 (2007) 1396-1401
-
(2007)
Int. J. Cancer
, vol.120
, pp. 1396-1401
-
-
Huang, Z.1
Komninou, D.2
Kleinman, W.3
Pinto, J.T.4
Gilhooly, E.M.5
Calcagnotto, A.6
Richie Jr., J.P.7
-
46
-
-
0036549015
-
Conditional mouse models of sporadic cancer
-
Jonkers J., and Berns A. Conditional mouse models of sporadic cancer. Nat. Rev. Cancer 2 (2002) 251-265
-
(2002)
Nat. Rev. Cancer
, vol.2
, pp. 251-265
-
-
Jonkers, J.1
Berns, A.2
-
47
-
-
0035912756
-
Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli
-
Blaisdell J.O., and Wallace S.S. Abortive base-excision repair of radiation-induced clustered DNA lesions in Escherichia coli. Proc. Natl. Acad. Sci. U.S.A. 98 (2001) 7426-7430
-
(2001)
Proc. Natl. Acad. Sci. U.S.A.
, vol.98
, pp. 7426-7430
-
-
Blaisdell, J.O.1
Wallace, S.S.2
-
48
-
-
33750622197
-
Subcellular compartmentalization of glutathione: correlations with parameters of oxidative stress related to genotoxicity
-
Green R.M., Graham M., O'Donovan M.R., Chipman J.K., and Hodges N.J. Subcellular compartmentalization of glutathione: correlations with parameters of oxidative stress related to genotoxicity. Mutagenesis 21 (2006) 383-390
-
(2006)
Mutagenesis
, vol.21
, pp. 383-390
-
-
Green, R.M.1
Graham, M.2
O'Donovan, M.R.3
Chipman, J.K.4
Hodges, N.J.5
-
49
-
-
0029033862
-
Mitochondrial changes associated with glutathione deficiency
-
Meister A. Mitochondrial changes associated with glutathione deficiency. Biochim. Biophys. Acta 1271 (1995) 35-42
-
(1995)
Biochim. Biophys. Acta
, vol.1271
, pp. 35-42
-
-
Meister, A.1
-
50
-
-
0031306970
-
DNA damage from oxidants: influence of lesion complexity and chromatin organization
-
Olive P.L., and Johnston P.J. DNA damage from oxidants: influence of lesion complexity and chromatin organization. Oncol. Res. 9 (1997) 287-294
-
(1997)
Oncol. Res.
, vol.9
, pp. 287-294
-
-
Olive, P.L.1
Johnston, P.J.2
-
51
-
-
23744439082
-
Gene expression responses to DNA damage are altered in human aging and in Werner Syndrome
-
Kyng K.J., May A., Stevnsner T., Becker K.G., Kolvra S., and Bohr V.A. Gene expression responses to DNA damage are altered in human aging and in Werner Syndrome. Oncogene 24 (2005) 5026-5042
-
(2005)
Oncogene
, vol.24
, pp. 5026-5042
-
-
Kyng, K.J.1
May, A.2
Stevnsner, T.3
Becker, K.G.4
Kolvra, S.5
Bohr, V.A.6
-
52
-
-
0031825679
-
Effects of DNA double-strand and single-strand breaks on intrachromosomal recombination events in cell-cycle-arrested yeast cells
-
Galli A., and Schiestl R.H. Effects of DNA double-strand and single-strand breaks on intrachromosomal recombination events in cell-cycle-arrested yeast cells. Genetics 149 (1998) 1235-1250
-
(1998)
Genetics
, vol.149
, pp. 1235-1250
-
-
Galli, A.1
Schiestl, R.H.2
-
53
-
-
3142768860
-
Conservative homologous recombination preferentially repairs DNA double-strand breaks in the S phase of the cell cycle in human cells
-
Saleh-Gohari N., and Helleday T. Conservative homologous recombination preferentially repairs DNA double-strand breaks in the S phase of the cell cycle in human cells. Nucleic Acids Res. 32 (2004) 3683-3688
-
(2004)
Nucleic Acids Res.
, vol.32
, pp. 3683-3688
-
-
Saleh-Gohari, N.1
Helleday, T.2
-
54
-
-
0035844242
-
Interactions between the Werner syndrome helicase and DNA polymerase delta specifically facilitate copying of tetraplex and hairpin structures of the d(CGG)n trinucleotide repeat sequence
-
Kamath-Loeb A.S., Loeb L.A., Johansson E., Burgers P.M., and Fry M. Interactions between the Werner syndrome helicase and DNA polymerase delta specifically facilitate copying of tetraplex and hairpin structures of the d(CGG)n trinucleotide repeat sequence. J. Biol. Chem. 276 (2001) 16439-16446
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 16439-16446
-
-
Kamath-Loeb, A.S.1
Loeb, L.A.2
Johansson, E.3
Burgers, P.M.4
Fry, M.5
-
56
-
-
33751581731
-
The Werner and Bloom syndrome proteins catalyze regression of a model replication fork
-
Machwe A., Xiao L., Groden J., and Orren D.K. The Werner and Bloom syndrome proteins catalyze regression of a model replication fork. Biochemistry 45 (2006) 13939-13946
-
(2006)
Biochemistry
, vol.45
, pp. 13939-13946
-
-
Machwe, A.1
Xiao, L.2
Groden, J.3
Orren, D.K.4
-
57
-
-
33646846505
-
Inhibition of Werner syndrome helicase activity by benzo[a]pyrene diol epoxide adducts can be overcome by replication protein A
-
Choudhary S., Doherty K.M., Handy C.J., Sayer J.M., Yagi H., Jerina D.M., and Brosh Jr. R.M. Inhibition of Werner syndrome helicase activity by benzo[a]pyrene diol epoxide adducts can be overcome by replication protein A. J. Biol. Chem. 281 (2006) 6000-6009
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 6000-6009
-
-
Choudhary, S.1
Doherty, K.M.2
Handy, C.J.3
Sayer, J.M.4
Yagi, H.5
Jerina, D.M.6
Brosh Jr., R.M.7
-
58
-
-
0742288051
-
WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork
-
Sharma S., Otterlei M., Sommers J.A., Driscoll H.C., Dianov G.L., Kao H.I., Bambara R.A., and Brosh Jr. R.M. WRN helicase and FEN-1 form a complex upon replication arrest and together process branchmigrating DNA structures associated with the replication fork. Mol. Biol. Cell 15 (2004) 734-750
-
(2004)
Mol. Biol. Cell
, vol.15
, pp. 734-750
-
-
Sharma, S.1
Otterlei, M.2
Sommers, J.A.3
Driscoll, H.C.4
Dianov, G.L.5
Kao, H.I.6
Bambara, R.A.7
Brosh Jr., R.M.8
-
59
-
-
33947401804
-
Correction of proliferation and drug sensitivity defects in the progeroid Werner's Syndrome by Holliday junction resolution
-
Rodriguez-Lopez A.M., Whitby M.C., Borer C.M., Bachler M.A., and Cox L.S. Correction of proliferation and drug sensitivity defects in the progeroid Werner's Syndrome by Holliday junction resolution. Rejuvenation Res. 10 (2007) 27-40
-
(2007)
Rejuvenation Res.
, vol.10
, pp. 27-40
-
-
Rodriguez-Lopez, A.M.1
Whitby, M.C.2
Borer, C.M.3
Bachler, M.A.4
Cox, L.S.5
|