Ceramide and raft signaling are linked with each other in UVA radiation-induced gene expression

Oncogene

Volumn 27, Issue 35, 2008, Pages 4768-4778

  Grether Beck, S ^a   Salahshour Fard, M ^a   Timmer, A ^a   Brenden, H ^a   Felsner, I ^a   Walli, R ^a   Fullekrug J ^b   Krutmann, J ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

^b UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

Ceramide; Rafts; Signaling; UVA

Indexed keywords

CERAMIDE; CHOLESTEROL; PHYTOSTEROL; SPHINGOMYELIN;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION; HUMAN; HUMAN CELL; LIPID COMPOSITION; LIPID RAFT; NEWBORN; NORMAL HUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; SOLAR RADIATION; ULTRAVIOLET A RADIATION;

CERAMIDES; CHOLESTEROL; GENE EXPRESSION; HUMANS; KERATINOCYTES; LIPID METABOLISM; MEMBRANE MICRODOMAINS; PHYTOSTEROLS; SIGNAL TRANSDUCTION; SPHINGOMYELINS; ULTRAVIOLET RAYS;

EID: 49649117494     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2008.116     Document Type: Article

References (64)

1. Anderson RGW. (1993). Caveolae: where incoming and outgoing messengers meet. Proc Natl Acad Sci USA 90: 10909-10913.
2. Anstey AV, Ryan A, Rhodes LE, Charman CR, Arlett CF, Tyrrell RM et al. (1999). Characterization of photosensitivity in the Smith-Lemli-Opitz syndrome: a new congenital photosensitivity syndrome. Br J Dermatol 141: 406-414.
3. Anstey AV, Taylor CR. (1999). Photosensitivity in the Smith-Lemli-Opitz syndrome: the US experience of a new congenital photosensitivity syndrome. J Am Acad Dermatol 41: 121-123.
4. Azurdia RM, Anstey AV, Rhodes LE. (2001). Cholesterol supplementation objectively reduces photosensitivity in the Smith-Lemli-Opitz syndrome. J Dermatol 144: 143-145.
5. Bachowski GJ, Thomas JP, Girotti AW. (1988). Ascorbate-enhanced lipid peroxidation in photooxidized cell membranes: cholesterol product analysis as a probe of reaction mechanism. Lipids 23: 580-586.
6. Batta AK, Tint GS, Shefer S, Abuelo D, Salen G. (1995). Identification of 8-dehydrocholesterol (cholesta-5,8-dien-3 beta-ol) in patients with Smith-Lemli-Opitz syndrome. J Lipid Res 36: 705-713.
7. Benting JH, Rietveld AG, Simons K. (1999). N-glycans mediate the apical sortingof a GPI-anchored, raft-associated protein in Madin-Darby canine kidney cells. J Cell Biol 146: 313-320.
8. Bradford MM. (1976). A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254.
9. Brown DA, London E. (1998). Functions of lipid rafts in biological membranes. Annu Rev Cell Dev Biol 14: 111-136.
10. Brown DA, London E. (2000). Structure and function of sphingolipid- and cholesterol-rich membrane rafts. J Biol Chem 275: 17221-17224.
11. Charman CR, Ryan A, Tyrrell RM, Pearse AD, Arlett CF, Kurwa HA et al. (1998). Photosensitivity associated with the Smith-Lemli-Opitz syndrome. Br J Dermatol 138: 885-888.
12. Dignam JD, Martin PL, Skastry BS, Roeder RGG. (1983). Eukaryotic gene transcription with purified components. Methods Enzymol 101: 582-598.
13. Emsley J, King SL, Bergelson JM, Liddington RC. (1997). Crystal structure of the I domain from integrin alpha2beta1. J Biol Chem 272: 28512-28517.
14. Fitzky BU, Witsch-Baumgartner M, Erdel M, Lee JN, Paik Y-K, Glossmann H et al. (1998). Mutations in the delta7-sterol reductase gene in patients with the Smith-Lemli-Opitz syndrome. Proc Natl Acad Sci USA 95: 8181-8186.
15. Folch J, Lees M, Sloane-Stanley GH. (1957). A simple method for the isolation and purification of total lipides from animal tissues. J Biol Chem 226: 497-509.
16. Fukasawa M, Nishijima M, Itabe H, Takano T, Hanada K. (2000). Reduction of sphingomyelin level without accumulation of ceramide in Chinese hamster ovary cells affects detergent-resistant membrane domains and enhances cellular cholesterol efflux to methyl-beta-cyclodextrin. J Biol Chem 275: 34028-34034.
17. Girotti AW. (1992). Photosensitized oxidation of cholesterol in biological systems: reaction pathways, cytotoxic effects and defense mechanisms. J Photochem Photobiol 13: 105-118.
18. Girotti AW. (1998). Lipid hydroperoxide generation, turnover, and effector action in biological systems. J Lipid Res 39: 1529-1542.
19. Girotti AW, Korytowski W. (2000). Cholesterol as a singlet oxygen detector in biological systems. Methods Enzymol 319: 85-100.
20. Gniadecki R, Christoffersen N, Wulf HC. (2002). Cholesterol-rich plasma membrane domains (lipid rafts) in keratinocytes: importance in the baseline and UVA-induced generation of reactive oxygen species. J Invest Dermatol 118: 582-588.
21. Grether-Beck S, Bonizzi G, Schmitt-Brenden H, Felsner I, Timmer A, Sies H et al. (2000). Non-enzymatic triggering of the ceramide signalling cascade by solar UVA radiation. EMBO J 19: 5793-5800.
22. Grether-Beck S, Felsner I, Brenden H, Krutmann J. (2003). Mitochondrial cytochrome c release mediates ceramide-induced activator protein 2 activation and gene expression in keratinocytes. J Biol Chem 278: 47498-47507.
23. Grether-Beck S, Olaizola-Horn S, Schmitt H, Grewe M, Jahnke A, Johnson JP et al. (1996). Activation of transcription factor AP-2 mediates UVA radiation- and singlet oxygen-induced expression of the human intercellular adhesion molecule 1 gene. Proc Natl Acad Sci USA 93: 14586-14591.
24. Grether-Beck S, Timmer A, Felsner I, Brenden H, Brammertz D, Krutmann J. (2005). Ultraviolet A-induced signaling involves a ceramide-mediated autocrine loop leadingto ceramide de novo synthesis. J Invest. Dermatol 125: 545-553.
25. Gulbins E, Li PL. (2006). Physiological and pathophysiological aspects of ceramide. Am J Physiol Regul Integr Comp Physiol 290: R11-R26.
26. Gustavsson J, Parpal S, Karlsson M, Ramsing C, Thorn H, Borg M et al. (1999). Localization of the insulin receptor in caveolae of adipocyte plasma membrane. FASEB J 13: 1961-1971.
27. Johnston I, Johnston LJ. (2006). Localization of the insulin receptor in caveolae of adipocyte plasma membrane. Langmuir 22: 11284-11289.
28. Kashkar H, Wiegmann K, Yazdanpanah B, Haubert D, Krönke M. (2005). Acid sphingomyelinase is indispensable for UV light-induced Bax conformational change at the mitochondrial membrane. J Biol Chem 280: 20804-20813.
29. Kim JB, Spotts GD, Halvorsen Y-D, Shih H-M, Ellenberger T et al. (1995). Dual DNA binding specificity of ADD1/SREBP1 controlled by a single amino acid in the basic helix-loop-helix domain. Mol Cell Biol 15: 2582-2588.
30. Kolesnick RN, Goni FM, Alonso A. (2000). Compartmentalization of ceramide signaling: physical foundations and biological effects. J Cell Physiol 184: 285-300.
31. Korytowski W, Girotti AW. (1999). Singlet oxygen adducts of cholesterol: photogeneration and reductive turnover in membrane systems. Photochem Photobiol 70: 484-489.
32. Linnik KM, Herscovitz H. (1998). Multiple molecular chaperones interact with apolipoprotein B during its maturation. The network of endoplasmic reticulum-resident chaperones (ERp72, GRP94, calreticulin, and BiP) interacts with apolipoprotein b regardless of its lipidation state. J Biol Chem 273: 21368-21373.
33. Liu P, Anderson RGW. (1995). Compartmentalized production of ceramide at the cell surface. J Biol Chem 270: 27179-27185.
34. McCallum FS, Maden BE. (1985). Human 18S ribosomal RNA sequence inferred from DNA sequence. Variations in 18S sequences and secondary modification patterns between vertebrates. Biochem J 232: 725-733.
35. Megha, London E. (2004). Ceramide selectively displaces cholesterol from ordered lipid domains (rafts): implications for lipid raft structure and function. J Biol Chem 279: 9997-10004.
36. Neufeld EB, Cooney AM, Pitha J, Dawidowicz EA, Dwyer NK, Pentchev PG et al. (1996). Intracellular trafficking of cholesterol monitored with a cyclodextrin. J Biol Chem 271: 21604-21613.
37. Pike LJ, Han X, Chung K-N, Gross RW. (2002). Lipid rafts are enriched in arachidonic acid and plasmenylethanolamine and their composition is independent of caveolin-1 expression: a quantitative electrospray ionization/mass spectrometric analysis. Biochemistry 41: 2075-2088.
38. Ponte P, Ng SY, Engel J, Gunning P, Kedes L. (1984). Evolutionary conservation in the untranslated regions of actin mRNAs: DNA sequence of a human beta-actin cDNA. Nucleic Acids Res 12: 1687-1696.
39. Reiterer G, MacDonald R, Browning JD, Morrow J, Matveev SV, Daugherty A et al. (2005). Zinc deficiency increases plasma lipids and atherosclerotic markers in LDL-receptor-deficient mice. J Nutr 135: 2114-2118.
40. Ridgway ND, Lagace TA, Cook HW, Byers DM. (1998). Differential effects of sphingomyelin hydrolysis and cholesterol transport on oxysterol-binding protein phosphorylation and Golgi localization. J Biol Chem 273: 31621-31628.
41. Rotolo JA, Zhang J, Donepudi M, Lee H, Fuks Z, Kolesnick R. (2005). Caspase-dependent and -independent activation of acid sphingomyelinase signaling. J Biol Chem 280: 26425-26434.
42. Schmuth M, Elias PM, Hanley K, Lau P, Moser A, Willson TM et al. (2004). The effect of LXR activators on AP-1 proteins in keratinocytes. J Invest Dermatol 123: 41-48.
43. Schnitzer JE, Oh P, Pinney E, Allard J. (1994). Filipin-sensitive caveolae-mediated transport in endothelium: reduced transcytosis, scavenger endocytosis, and capillary permeability of select macromolecules. J Cell Biol 127: 1217-1232.
44. Schwarz T. (2005). Biological effects of UV radiation on keratinocytes and Langerhans cells. Exp Dermatol 14: 788-789.
45. Simons K, Ehehalt R. (2002). Cholesterol, lipid rafts, and disease. J Clin Invest 10: 597-603.
46. Simons K, Ikonen E. (1997). Functional rafts in cell membranes. Nature 387: 569-572.
47. Simons K, Toomre D. (2000). Lipid rafts and signal transduction. Nat Rev Mol Cell Biol 1: 31-39.
48. Simons K, van Meer G. (1988). Lipid sorting in epithelial cells. Biochemistry 27: 6197-6202.
49. Slotte JP, Bierman EL. (1988). Depletion of plasma-membrane sphingomyelin rapidly alters the distribution of cholesterol between plasma membranes and intracellular cholesterol pools in cultured fibroblasts. Biochem J 250: 653-658.
50. Smith DW, Lemli L, Opitz JM. (1964). A newly recognized syndrome of multiple congenital anomalies. J Pediatr 64: 210-217.
51. Stade BG, Messer G, Riethmüller G, Johnson JP. (1990). Structural characteristics of the 5′ region of the human ICAM-1 gene. Immunobiology 182: 79-87.
52. Staunton DE, Marlin SD, Stratowa C, Dustin ML, Springer TA. (1988). Primary structure of ICAM-1 demonstrates interaction between members of the immunoglobulin and integrin supergene families. Cell 52: 925-933.
53. Tint GS, Irons M, Elias ER, Batta AK, Frieden R, Chen ST et al. (1994). Defective cholesterol biosynthesis associated with the Smith-Lemli-Opitz syndrome. N Engl J Med 330: 107-113.
54. Tyrrell RM. (2004). Solar ultraviolet A radiation: an oxidizing skin carcinogen that activates heme oxygenase-1. Antioxid Redox Signal 6: 835-840.
55. Tyrrell RM, Reeve VE. (2006). Potential protection of skin by acute UVA irradiation - from cellular to animal models. Prog Biophys Mol Biol 92: 86-91.
56. Vainio S, Heino S, Mansson J-E, Fredman P, Kuismanen E, Vaarala O et al. (2002). Dynamic association of human insulin receptor with lipid rafts in cells lacking caveolae. EMBO Rep 3: 95-100.
57. Valencia A, Kochevar IE. (2006). Ultraviolet A induces apoptosis via reactive oxygen species in a model for Smith-Lemli-Opitz syndrome. Free Radic Biol Med 15: 641-650.
58. Vandekerckhove J, Weber K. (1978). Mammalian cytoplasmic actins are the products of at least two genes and differ in primary structure in at least 25 identified positions from skeletal muscle actins. Proc Natl Acad Sci USA 75: 1106-1110.
59. Wolf C, Chevy F, Pham J, Kolf-Clauw M, Citadelle D, Mulliez N et al. (1996). Changes in serum sterols of rats treated with 7-dehydrocholesterol-delta 7-reductase inhibitors: comparison to levels in humans with Smith-Lemli-Opitz syndrome. J Lipid Res 37: 1325-1333.
60. XU F, Rychnovsky SD, Belani JD, Hobbs HH, Cohen JC, Rawson RB. (2005). Dual roles for cholesterol in mammalian cells. Proc Natl Acad Sci USA 102: 14551-14556.
61. Yancey PG, Rodrigueza WV, Kilsdonk EPC, Stoudt GW, Johnson WJ, Phillips C et al. (1996). Cellular cholesterol efflux mediated by cyclodextrins. Demonstration of kinetic pools and mechanism of efflux. J Biol Chem 271: 16026-16034.
62. Yang N, Huang Y, Jiang J, Frank SJ. (2004). Caveolar and lipid raft localization of the growth hormone receptor and its signaling elements: impact on growth hormone signaling. J Biol Chem 279: 20898-20905.
63. Yang T, Kozopas KM, Craig RW. (1995). The intracellular distribution and pattern of expression of Mcl-1 overlap with, but are not identical to, those of Bcl-2. J Cell Biol 128: 1173-1184.
64. Zhang Y, Mattjus P, Schmid PC, Dong Z, Zhong S, Ma W-Y et al. (2001). Involvement of the acid sphingomyelinase pathway in UVA-induced apoptosis. J Biol Chem 276: 11775-11782.