Ultraviolet A-induced signaling involves a ceramide-mediated autocrine loop leading to ceramide de novo synthesis

Journal of Investigative Dermatology

Volumn 125, Issue 3, 2005, Pages 545-553

  Grether Beck, Susanne ^a   Timmer, Andreas ^a   Felsner, Ingo ^a   Brenden, Heidi ^a   Brammertz, Daniela ^a   Krutmann, Jean ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Autocrine loop; Ceramide; Gene expression; Signaling; UVA

Indexed keywords

ALPHA TOCOPHEROL; CERAMIDE; CHOLESTEROL; ECTOINE; INTERCELLULAR ADHESION MOLECULE 1; MESSENGER RNA; SERINE PALMITOYLTRANSFERASE; TRANSCRIPTION FACTOR AP 2; ACYLTRANSFERASE; DIAMINO ACID; DNA BINDING PROTEIN; N CAPROYLSPHINGOSINE; N-CAPROYLSPHINGOSINE; SPTLC2 PROTEIN, HUMAN; TRANSCRIPTION FACTOR;

ARTICLE; CELL CULTURE; CONTROLLED STUDY; ENZYME ACTIVATION; FLOW CYTOMETRY; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; KERATINOCYTE; KINETICS; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; SYNTHESIS; ULTRAVIOLET A RADIATION; ULTRAVIOLET IRRADIATION; AUTOCRINE EFFECT; BIOSYNTHESIS; DRUG ANTAGONISM; DRUG EFFECT; GENETICS; METABOLISM; RADIATION EXPOSURE; ULTRAVIOLET RADIATION; UPREGULATION;

ACYLTRANSFERASES; AMINO ACIDS, DIAMINO; AUTOCRINE COMMUNICATION; CERAMIDES; CHOLESTEROL; DNA-BINDING PROTEINS; GENE EXPRESSION; HUMANS; INTERCELLULAR ADHESION MOLECULE-1; KERATINOCYTES; RNA, MESSENGER; SERINE C-PALMITOYLTRANSFERASE; TRANSCRIPTION FACTOR AP-2; TRANSCRIPTION FACTORS; ULTRAVIOLET RAYS; UP-REGULATION; VITAMIN E;

EID: 27144445085     PISSN: 0022202X     EISSN: 15231747     Source Type: Journal    
DOI: 10.1111/j.0022-202X.2005.23782.x     Document Type: Article

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