Changes in intracellular Ca2+ and pH in response to thapsigargin in human glioblastoma cells and normal astrocytes

American Journal of Physiology - Cell Physiology

Volumn 289, Issue 2 58-2, 2005, Pages

  Kovacs, Gergely Gy ^a   Zsembery, Akos ^d   Anderson, Susan J ^a   Komlosi, Peter ^b   Gillespie, G Yancey ^c   Bell, P Darwin ^a,b   Benos, Dale J ^a   Fuller, Catherine M ^a  

^a UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^b and Clinical Center   (United States)

^c University of Alabama at Birmingham   (United States)

^d SEMMELWEIS UNIVERSITY   (Hungary)

Author keywords

BCECF; fura 2; Store operated calcium channels

Indexed keywords

5 (N,N HEXAMETHYLENE)AMILORIDE; ADENOSINE TRIPHOSPHATASE (CALCIUM); AMILORIDE; CALCIUM CHANNEL; CALCIUM ION; FURA 2; SODIUM PROTON EXCHANGE PROTEIN; THAPSIGARGIN; CALCIUM; ENZYME INHIBITOR; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE;

ACIDIFICATION; ARTICLE; ASTROCYTE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CALCIUM TRANSPORT; CARCINOGENESIS; CELL PH; CONTROLLED STUDY; GLIOBLASTOMA; HUMAN; HUMAN CELL; PRIORITY JOURNAL; SARCOPLASMIC RETICULUM; SURVIVAL RATE; TUMOR CELL LINE; CELL PROLIFERATION; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENDOPLASMIC RETICULUM; INTRACELLULAR FLUID; METABOLISM; PH;

ASTROCYTES; CALCIUM; CALCIUM CHANNELS; CALCIUM-TRANSPORTING ATPASES; CELL LINE, TUMOR; CELL PROLIFERATION; ENDOPLASMIC RETICULUM; ENZYME INHIBITORS; GLIOBLASTOMA; HUMANS; HYDROGEN-ION CONCENTRATION; INTRACELLULAR FLUID; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; THAPSIGARGIN;

EID: 22444435792     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.00280.2004     Document Type: Article

References (39)

1. Bilmen JG and Michelangeli F. Inhibition of the type 1 inositol 1,4,5-triphosphate receptor by 2-aminoethoxydiphenylborate. Cell Signal 14: 955-960, 2002.
2. 2+ pumps by 2-aminoethoxydiphenyl borate (2-APB). Eur J Biochem 269: 3678-3687, 2002.
3. 2+ release. FASEB J 16: 1145-1150, 2002.
4. CBTRUS. Center of Brain Tumor Registry of the United States. 1995-1999 Data, 2000.
5. Chen YJ, Lin JK, and Lin-Shiau SY. Proliferation arrest and induction of CDK inhibitors p21 and p27 by depleting the calcium store in cultured C6 glioma cells. Eur J Cell Biol 78: 824-831, 1999.
6. Climent E, Sancho-Tello M, Minana R, Barettino D, and Guerri C. Astrocytes in culture express the full-length Trk-B receptor and respond to brain derived neurotrophic factor by changing intracellular calcium levels: effect of ethanol exposure in rats. Neurosci Lett 288: 53-56, 2000.
7. Ducret T, Boudina S, Sorin B, Vacher AM, Gourou I, Liugoro D, Guerin J, Bresson-Bepoldin L, and Vacher P. Effects of prolactin on intracellular calcium concentration and cell proliferation in human glioma cells. Glia 38: 200-214, 2002.
8. Ganz MB, Boyarsky G, Boron WF, and Sterzel RB. Effects of angiotensin II and vasopressin on intracellular pH of glomerular mesangial cells. Am J Physiol Renal Fluid Electrolyte Physiol 254: F787-F794, 1988.
9. Garcia-Martin ML, Herigault G, Remy C, Farion R, Ballesteros P, Coles JA, Cerdan S, and Ziegler A. Mapping extracellular pH in rat brain gliomas in vivo by 1H magnetic resonance spectroscopic imaging: comparison with maps of metabolites. Cancer Res 61: 6524-6531, 2001.
10. Gende OA. Capacitative calcium influx and intracellular pH cross-talk in human platelets. Platelets 14: 9-14, 2003.
11. 2+ entry in human pulmonary artery myocytes during proliferation. Am J Physiol Heart Circ Physiol 280: H746-H755, 2001.
12. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260: 3440-3450, 1985.
13. Hajnoczky G, Davies E, and Madesh M. Calcium signaling and apoptosis. Biochem Biophys Res Commun 304: 445-454, 2003.
14. Hegde M, Roscoe J, Cala PM, and Gorin FA. Amiloride kills malignant glioma cells independent of its inhibition the sodium-hydrogen exchanger. J Pharmacol Exp Ther 101124/jpet 103065029, 2004.
15. +, pH and membrane potential. J Physiol 464: 1-13, 1993.
16. Kraft R, Krause P, Jung S, Basrai D, Liebmann L, Bolz J, and Patt S. BK channel openers inhibit migration of human glioma cells. Pflügers Arch 446: 248-255, 2003.
17. 2+ pools and cell growth. J Biol Chem 276: 47608-47614, 2001.
18. Madshus IH. Regulation of intracellular pH in eukaryotic cells. Biochem J 250: 1-8, 1988.
19. Maintz D, Heindel W, Kugel H, Jaeger R, and Lackner KJ. Phosphorus-31 MR spectroscopy of normal adult human brain and brain tumours. NMR Biomed 15: 18-27, 2002.
20. McLean LA, Roscoe J, Jorgensen NK, Gorin FA, and Cala PM. Malignant gliomas display altered pH regulation by NHE1 compared with nontransformed astrocytes. Am J Physiol Cell Physiol 278: C676-C688, 2000.
21. 2+ stores in permeabilized A7r5 cells. Cell Calcium 29: 111-116, 2001.
22. 2+ storage-dependent cellular proliferation. Exp Cell Res 244: 310-318, 1998.
23. Rizzuto R, Pinton P, Ferrari D, Chami M, Szabadkai Gy, Magalhaes PJ, Di Virgilio F, and Pozzan T. Calcium and apoptosis: facts and hypotheses. Oncogene 22: 8619-8627, 2003.
24. Ronde P, Giannone G, Gersymova I, Stoeckel H, Takeda K, and Haiech J. Mechanism of calcium oscillations in migrating human astrocytoma cells. Biochem Biophys Acta 1498: 273-280, 2000.
25. Rose CR, Blum R, Pichler B, Lepler A, Kafitz KW, and Konnerth A. Truncated TrkB-T1 mediates neurotrophin-evoked calcium signaling in glia cells. Nature 426: 74-78, 2003.
26. + exchanger for tumor growth. Cancer Res 49: 205-211, 1989.
27. Shrode LD, Tapper H, and Grinstein S. Role of intracellular pH in proliferation, transformation and apoptosis. J Bioenerg Biomembr 29: 393-399, 1997.
28. Simon VR and Moran MF. SERCA activity is required for timely progression through G1/S. Cell Prolif 34: 15-30, 2001.
29. 2+ current in human prostate cancer LNCaP cells: involvement in apoptosis. J Physiol 527: 71-83, 2000.
30. Soboloff J, Zhang Y, Minden M, and Berger SA. Sensitivity of myeloid leukemia cells to calcium influx blockade: application to bone marrow purging. Exp Hematol 30: 1219-1226, 2002.
31. 2+ entry and attenuates pulmonary artery smooth muscle cell proliferation. Am J Physiol Lung Cell Mol Physiol 283: L144-L155, 2002.
32. 2+ stores in cell cycle progression at the G1/S boundary in serum-stimulated human fibroblasts. FEBS Lett 360: 173-176, 1995.
33. Tangrea JA, Albert PS, Lanza E, Woodson K, Corle D, Hasson M, Burt R, Caan B, Paskett E, Iber F, Kikendall JW, Lance P, Shike M, Weissfel J, and Schatzkin A (Polyp Prevention Study Group). Non-steroidal anti-inflammatory drug use in associated with reduction in recurrence of advanced and non-advanced colorectal adenomas (United States). Cancer Causes Control 14: 403-411, 2003.
34. Thun MJ, Namboodiri MM, and Heath CW Jr. Aspirin use and reduced risk of fatal colon cancer. N Engl J Med 325: 1593-1596, 1991.
35. 2+-ATPases. Trends Pharmacol Sci 19: 131-135, 1998.
36. Tu MT, Luo SF, Wang CC, Chien CS, Chiu CT, Lin CC, and Yang CM. P2Y(2) receptor-mediated proliferation of C(6) glioma cells via activation of Ras/Raf/MEK/MAPK pathway. Br J Pharmacol 129: 1481-1489, 2000.
37. 2+ ATPase (SERCA) inhibitors identify a novel calcium pool in the central nervous system. J Neurochem 87: 30-43, 2003.
38. Weiss H, Amberger A, Widschwendter M, Margreiter R, Ofner D, and Dietl P. Inhibition of store-operated calcium entry contributes to the anti-proliferative effect of non-steroidal anti-inflammatory drugs in human colon cancer cells. Int J Cancer 92: 877-882, 2001.
39. Yu Y, Sweeney M, Zhang S, Platoshyn O, Landsber J, Rothman A, and Yuan JX-J. PDGF stimulates pulmonary vascular smooth muscle cell proliferation by-upregulating TRPC6 expression. Am J Physiol Cell Physiol 284: C316-C330, 2003.