The anti-non-gal xenoantibody response to xenoantigens on gal knockout pig cells is encoded by a restricted number of germline progenitors

American Journal of Transplantation

Volumn 8, Issue 9, 2008, Pages 1829-1839

  Kiernan, K ^a,b   Harnden, I ^a,b   Gunthart, M ^a   Gregory, C ^c   Meisner, J ^a,b   Kearns Jonker, M ^a,b  

^a CHILDREN S HOSPITAL LOS ANGELES   (United States)

^b UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

1,3 galactosyltransferase gene knockout; Pig; Primate; VH3 immunoglobulin genes; Xenoantibodies; Xenotransplantation

Indexed keywords

ALPHA 1,3 GALACTOSYLTRANSFERASE; CARBOHYDRATE; GALACTOSE; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; ISOGLOBOTRIAOSYLCERAMIDE SYNTHASE; LENTIVIRUS VECTOR; SYNTHETASE;

ANIMAL CELL; ANTIBODY RESPONSE; ANTIGEN BINDING; ARTICLE; CONTROLLED STUDY; CROSS REACTION; ENDOTHELIUM CELL; FETUS; GENE IDENTIFICATION; GENE LIBRARY; IMMUNIZATION; IMMUNOGLOBULIN GENE; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN STRUCTURE; RHESUS MONKEY; SWINE;

ANIMALS; ANTIBODIES, HETEROPHILE; ANTIGENS, HETEROPHILE; EPITOPES; GALACTOSYLTRANSFERASES; GENES, IMMUNOGLOBULIN; GENES, IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN HEAVY CHAINS; MACACA MULATTA; SWINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 49649085309     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2008.02337.x     Document Type: Article

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