Mechanistic studies on the inactivation of papain by epoxysuccinyl inhibitors

Journal of Medicinal Chemistry

Volumn 39, Issue 17, 1996, Pages 3357-3366

  Meara, Joseph P ^a,b   Rich, Daniel H ^a  

^a UNIVERSITY OF WISCONSIN MADISON   (United States)

^b Molecumetics Ltd   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALOXISTATIN ACID; CARBONYL DERIVATIVE; CYSTEINE PROTEINASE INHIBITOR; EPOXIDE; PAPAIN INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME INACTIVATION; INHIBITION KINETICS; PH;

CYSTEINE PROTEINASE INHIBITORS; EPOXY COMPOUNDS; HYDROGEN-ION CONCENTRATION; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PAPAIN; STRUCTURE-ACTIVITY RELATIONSHIP; SUCCINATES;

EID: 0029744988     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950445b     Document Type: Article

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