Ab initio quantum mechanical and density functional theory calculations on nucleophile- and nucleophile and acid-catalyzed opening of an epoxide ring: A model for the covalent binding of epoxyalkyl inhibitors to the active site of glycosidases

Journal of Organic Chemistry

Volumn 63, Issue 23, 1998, Pages 8157-8162

  Laitinen, Tuomo ^a   Rouvinen, Juha ^a   Peräkylä, Mikael ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; EPOXIDE; GLYCOSIDASE;

ARTICLE; CHEMICAL REACTION; COVALENT BOND; ENERGY TRANSFER; ENZYME ACTIVE SITE; ENZYME INHIBITOR COMPLEX; MODEL; REACTION ANALYSIS; STRUCTURE ANALYSIS;

EID: 0032514985     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo980532m     Document Type: Article

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