High frequency of hypermethylation of p14, p15 and p16 in oral pre-cancerous lesions associated with betel-quid chewing in Sri Lanka

Journal of Oral Pathology and Medicine

Volumn 37, Issue 8, 2008, Pages 475-479

  Takeshima, Maiko ^a   Saitoh, Masato ^a   Kusano, Kaoru ^a   Nagayasu, Hiroki ^a   Kurashige, Yoshihito ^a   Malsantha, Muthumala ^b   Arakawa, Toshiya ^b   Takuma, Taishin ^a   Chiba, Itsuo ^a   Kaku, Tohru ^a   Shibata, Toshiyuki ^c   Abiko, Yoshihiro ^a  

^a HEALTH SCIENCES UNIVERSITY OF HOKKAIDO   (Japan)

^b General Hospital Kalutara

^c GIFU UNIVERSITY   (Japan)

Author keywords

Leukoplakia; Oral mucosa; Oral pre cancer; Submucous fibrosis; Tobacco

Indexed keywords

PROTEIN P14; PROTEIN P15; PROTEIN P16; PROTEIN P53;

ARTICLE; BETEL NUT; CONTROLLED STUDY; CPG ISLAND; DISEASE SEVERITY; DYSPLASIA; FIBROSIS; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LEUKOPLAKIA; MAJOR CLINICAL STUDY; METHYLATION; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SRI LANKA; STAINING; SUBMUCOSA;

ALLELES; ARECA; CPG ISLANDS; CYCLIN-DEPENDENT KINASE INHIBITOR P15; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYTOSINE; DNA METHYLATION; EPITHELIUM; GENES, P16; GENES, P53; HUMANS; LEUKOPLAKIA, ORAL; MOUTH NEOPLASMS; MUTATION; ORAL SUBMUCOUS FIBROSIS; PRECANCEROUS CONDITIONS; SRI LANKA; TUMOR SUPPRESSOR PROTEIN P14ARF; TUMOR SUPPRESSOR PROTEIN P53; URACIL;

EID: 49249139883     PISSN: 09042512     EISSN: 16000714     Source Type: Journal    
DOI: 10.1111/j.1600-0714.2008.00644.x     Document Type: Article

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