Smoking and drinking can induce p15 methylation in the upper aerodigestive tract of healthy individuals and patients with head and neck squamous cell carcinoma

Cancer

Volumn 101, Issue 1, 2004, Pages 125-132

  Chang, Hsiao Wen ^a   Ling, Guang Sheng ^a   Wei, William Ignace ^a   Yuen, Anthony Po Wing ^a,b  

^a UNIVERSITY OF HONG KONG   (Hong Kong)

^b QUEEN MARY HOSPITAL   (Hong Kong)

Author keywords

Head and neck squamous cell carcinoma; Methylation index; Mouth and throat rinsing fluid; p15 gene; Promoter hypermethylation

Indexed keywords

BETA ACTIN; PROTEIN P15;

ADULT; AGED; ALCOHOL CONSUMPTION; ARTICLE; CARCINOGENESIS; CLINICAL ARTICLE; CONTROLLED STUDY; DIGESTIVE SYSTEM; FEMALE; GENE FUNCTION; HEAD CANCER; HUMAN; MALE; MOUTH; NECK CANCER; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN METHYLATION; SMOKING; SQUAMOUS CELL CARCINOMA; THROAT; TOBACCO; TUMOR BIOPSY; TUMOR CELL; TUMOR SUPPRESSOR GENE;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ALCOHOL DRINKING; BASE SEQUENCE; CARCINOMA, SQUAMOUS CELL; DNA METHYLATION; FEMALE; GENES, TUMOR SUPPRESSOR; HEAD AND NECK NEOPLASMS; HUMANS; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; MOUTH; PHARYNX; PROMOTER REGIONS (GENETICS); REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SMOKING;

EID: 3042580177     PISSN: 0008543X     EISSN: None     Source Type: Journal    
DOI: 10.1002/cncr.20323     Document Type: Article

References (22)

1. Weber A, Tannapfel A, Wittekind C, Bootz F. Carcinogen-induced site-specific mutagenesis and genetic susceptibility in squamous cell carcinoma of the head and neck. Onkologie. 2002;25:8-13.
2. Cancado RP, Yurgel LS, Filho MS. Evaluation of the nucleolar organizer region associated proteins in exfoliative cytology of normal buccal mucosa. Effect of smoking. Oral Oncol. 2001;37:446-454.
3. Zheng Z, Park JY, Guillemette C, Schantz SP, Lazarus P. Anti-p53 and anti-heat shock proteins antibodies in patients with malignant or pre-malignant lesions of the oral cavity. Anticancer Res. 2001;21:753-758.
4. Reed AL, Califano J, Cairns P, et al. High frequency of p16 (CDKN2/MTS-1/INK4A) inactivation in head and neck squamous cell carcinoma. Cancer Res. 1996;56:3630-3633.
5. Hasegawa M, Nelson HH, Peters E, Ringstrom E, Posner M, Kelsey KT. Patterns of gene promoter methylation in squamous cell cancer of the head and neck. Oncogene. 2002;21:4231-4236.
6. Chang HW, Chan A, Kwong DL, Wei WI, Sham JS, Yuen AP. Evaluation of hypermethylated tumor suppressor genes as tumor markers in mouth and throat rinsing fluid, nasopharyngeal swab and peripheral blood of nasopharygeal carcinoma patient. Int J Cancer. 2003;105:851-855.
7. Chang HW, Chan A, Kwong DL, Wei WI, Sham JS, Yuen AP. Detection of hypermethylated RIZ1 gene in primary tumor, mouth, and throat rinsing fluid, nasopharyngeal swab, and peripheral blood of nasopharyngeal carcinoma patients. Clin Cancer Res. 2003;9:1033-1038.
8. Mao L, Hruban RH, Boyle JO, Tockman M, Sidransky D. Detection of oncogene mutations in sputum precedes diagnosis of lung cancer. Cancer Res. 1994;54:1634-1637.
9. Hannon GJ, Beach D. p15INK4B is a potential effector of TGF-beta-induced cell cycle arrest. Nature. 1994;371:257-261.
10. Drexler HG. Review of alterations of the cyclin-dependent kinase inhibitor INK4 family genes p15, p16, p18 and p19 in human leukemia-lymphoma cells. Leukemia. 1998;12:845-859.
11. Sakashita K, Koike K, Kinoshita T, et al. Dynamic DNA methylation change in the CpG island region of p15 during human myeloid development. J Clin Invest. 2001;108:1195-1204.
12. Wong TS, Man M, Lam AKY, Wei WI, Kwong YL, Yuen APW. The study of p16 and p15 gene methylation in head and neck squamous cell carcinoma and their quantitative evaluation in plasma by real-time PCR. Eur J Cancer. 2003;39:1881-1887.
13. Lo YM, Wong IH, Zhang J, Tein MS, Ng MH, Hjelm NM. Quantitative analysis of aberrant p16 methylation using real-time quantitative methylation-specific polymerase chain reaction. Cancer Res. 1999;59:3899-3903.
14. Belinsky SA, Nikula KJ, Palmisano WA, et al. Aberrant methylation of p16(INK4a) is an early event in lung cancer and a potential biomarker for early diagnosis. Proc Natl Acad Sci USA. 1998;95:11891-1186.
15. Belinsky SA, Nikula KJ, Baylin SB, Issa JP. Increased cytosine DNA-methyltransferase activity is target-cell-specific and an early event in lung cancer. Proc Natl Acad Sci USA. 1996;93:4045-4050.
16. Goldman R, Shields PG. Food mutagens. J Nutr. 2003;133:965S-973S.
17. Jaenisch R, Bird A. Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals. Nat Genet. 2003;33:245-254.
18. Stern SJ, Degawa M, Martin MV, et al. Metabolic activation, DNA adducts, and H-ras mutations in human neoplastic and non-neoplastic laryngeal tissue. J Cell Biochem. 1993;17F(Suppl):129-137.
19. Gronau S, Koenig-Greger D, Jerg M, Riechelmann H. Gene polymorphisms in detoxification enzymes as susceptibility factor for head and neck cancer? Otolaryngol Head Neck Surg. 2003;128:674-680.
20. Mitra S, Chatterjee S, Panda CK, et al. Haplotype structure of TP53 locus in Indian population and possible association with head and neck cancer. Ann Hum Genet. 2003;67:26-34.
21. Oude Ophuis MB, Roelofs HM, van den Brandt PA, Peters WH, Manni JJ. Polymorphisms of the glutathione S-transferase P1 gene and head and neck cancer susceptibility. Head Neck. 2003;25:37-43.
22. Kersting M, Friedl C, Kraus A, Behn M, Pankow W, Schuermann M. Differential frequencies of p16(INK4a) promoter hypermethylation, p53 mutation, and K-ras mutation in exfoliative material mark the development of lung cancer in symptomatic chronic smokers. J Clin Oncol. 2000;18:3221-3229.