Topical doxycycline can induce expression of BDNF in transduced retinal pigment epithelial cells transplanted into the subretinal space

Investigative Ophthalmology and Visual Science

Volumn 49, Issue 8, 2008, Pages 3631-3639

  Abe, Toshiaki ^a   Wakusawa, Ryosuke ^a   Seto, Haruka ^a   Asai, Nobuharu ^a   Saito, Takae ^a   Nishida, Kohji ^a  

^a TOHOKU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; DOXYCYCLINE; EYE DROPS; LIPID; LIPOFECTAMINE; MESSENGER RNA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL TRANSPLANTATION; CONTROLLED STUDY; ELECTROPHYSIOLOGY; ELECTRORETINOGRAM; ENZYME LINKED IMMUNOSORBENT ASSAY; HISTOLOGY; IN VITRO STUDY; IN VIVO STUDY; LIGHT EXPOSURE; MALE; NONHUMAN; PHOTORECEPTOR; PHOTOTOXICITY; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; REAL TIME POLYMERASE CHAIN REACTION; RETINA; SHAM PROCEDURE; SIGNAL TRANSDUCTION; SUBRETINAL SPACE; UPREGULATION; WESTERN BLOTTING; ANIMAL; CELL LINE; CELL SURVIVAL; ELECTRORETINOGRAPHY; GENE EXPRESSION; GENETIC TRANSFECTION; GENETICS; METABOLISM; RADIATION EXPOSURE; RADIATION INJURY; RETINA DEGENERATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SPRAGUE DAWLEY RAT; TOPICAL DRUG ADMINISTRATION; TRANSPLANTATION;

ADMINISTRATION, TOPICAL; ANIMALS; BLOTTING, WESTERN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELL LINE; CELL SURVIVAL; CELL TRANSPLANTATION; DOXYCYCLINE; ELECTRORETINOGRAPHY; ENZYME-LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; LIPIDS; MALE; OPHTHALMIC SOLUTIONS; PIGMENT EPITHELIUM OF EYE; RADIATION INJURIES, EXPERIMENTAL; RATS; RATS, SPRAGUE-DAWLEY; RETINA; RETINAL DEGENERATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TRANSFECTION; UP-REGULATION;

EID: 49049108912     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.07-0947     Document Type: Article

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