EGF antagonizes TGF-β-induced tropoelastin expression in lung fibroblasts via stabilization of Smad corepressor TGIF

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 295, Issue 1, 2008, Pages

  Yang, Shenghong ^a   Nugent, Matthew A ^a,b   Panchenko, Mikhail P ^a,c  

^a BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Boston University   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Elastin; Neutrophil elastase

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; LEUKOCYTE ELASTASE; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TGIF; SMAD PROTEIN; SMAD2 PROTEIN; SMAD3 PROTEIN; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA; TROPOELASTIN; UNCLASSIFIED DRUG; EGFR PROTEIN, HUMAN; EGFR PROTEIN, RAT; EPIDERMAL GROWTH FACTOR; HOMEODOMAIN PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE KINASE; REPRESSOR PROTEIN; SMALL INTERFERING RNA; TGIF PROTEIN, MOUSE; TGIF1 PROTEIN, HUMAN;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; LUNG FIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; RAT; SIGNAL TRANSDUCTION; ANIMAL; BIOSYNTHESIS; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; FIBROBLAST; HUMAN; LUNG; METABOLISM; MOUSE; PHOSPHORYLATION; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ANIMALS; DOWN-REGULATION; EPIDERMAL GROWTH FACTOR; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; HOMEODOMAIN PROTEINS; HUMANS; LEUKOCYTE ELASTASE; LUNG; MAP KINASE KINASE KINASES; MAP KINASE SIGNALING SYSTEM; MICE; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; RECEPTOR, EPIDERMAL GROWTH FACTOR; REPRESSOR PROTEINS; RNA, SMALL INTERFERING; SMAD PROTEINS; TRANSFORMING GROWTH FACTOR BETA; TROPOELASTIN;

EID: 49049107987     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00289.2007     Document Type: Article

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