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Volumn 13, Issue 7, 2008, Pages 771-785

hScrib, a human homologue of Drosophila neoplastic tumor suppressor, is a novel death substrate targeted by caspase during the process of apoptosis

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ASPARTIC ACID; CASPASE; CASPASE 3 INHIBITOR; PROTEIN HSCRIB; RECOMBINANT ENZYME; TUMOR SUPPRESSOR PROTEIN; UVOMORULIN;

EID: 48949120838     PISSN: 13569597     EISSN: 13652443     Source Type: Journal    
DOI: 10.1111/j.1365-2443.2008.01204.x     Document Type: Article
Times cited : (6)

References (49)
  • 1
    • 12344293943 scopus 로고    scopus 로고
    • Scribble protein domain mapping reveals a multistep localization mechanism and domains necessary for establishing cortical polarity
    • Albertson, R., Chabu, C., Sheehan, A. & Doe, C.Q. (2004) Scribble protein domain mapping reveals a multistep localization mechanism and domains necessary for establishing cortical polarity. J. Cell Sci. 117, 6061-6070.
    • (2004) J. Cell Sci. , vol.117 , pp. 6061-6070
    • Albertson, R.1    Chabu, C.2    Sheehan, A.3    Doe, C.Q.4
  • 3
    • 10844272528 scopus 로고    scopus 로고
    • PDZ domain polarity complexes
    • Bilder, D. (2003) PDZ domain polarity complexes. Curr. Biol. 13, R661-R662.
    • (2003) Curr. Biol. , vol.13
    • Bilder, D.1
  • 4
    • 4043170088 scopus 로고    scopus 로고
    • Epithelial polarity and proliferation control: Links from the Drosophila neoplastic tumor suppressors
    • Bilder, D. (2004) Epithelial polarity and proliferation control: Links from the Drosophila neoplastic tumor suppressors. Genes Dev. 18, 1909-1925.
    • (2004) Genes Dev. , vol.18 , pp. 1909-1925
    • Bilder, D.1
  • 5
    • 0034628471 scopus 로고    scopus 로고
    • Localization of apical epithelial determinants by the basolateral PDZ protein Scribble
    • Bilder, D. & Perrimon, N. (2000) Localization of apical epithelial determinants by the basolateral PDZ protein Scribble. Nature 403, 676-680.
    • (2000) Nature , vol.403 , pp. 676-680
    • Bilder, D.1    Perrimon, N.2
  • 8
    • 0030707519 scopus 로고    scopus 로고
    • Dismantling cell-cell contacts during apoptosis is coupled to a caspase-dependent proteolytic cleavage of f-catenin
    • Brancolini, C., Lazarevic, D., Rodriguez, J. & Schneider, C. (1997) Dismantling cell-cell contacts during apoptosis is coupled to a caspase-dependent proteolytic cleavage of f-catenin. J. Cell Sci. 139, 759-771.
    • (1997) J. Cell Sci. , vol.139 , pp. 759-771
    • Brancolini, C.1    Lazarevic, D.2    Rodriguez, J.3    Schneider, C.4
  • 9
    • 0242641565 scopus 로고    scopus 로고
    • Scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila
    • Brumby, A.M. & Richardson, H.E. (2003) scribble mutants cooperate with oncogenic Ras or Notch to cause neoplastic overgrowth in Drosophila. EMBO J. 22, 5769-5779.
    • (2003) EMBO J. , vol.22 , pp. 5769-5779
    • Brumby, A.M.1    Richardson, H.E.2
  • 11
    • 34147094240 scopus 로고    scopus 로고
    • The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: Regulation of Rho GTPase recruitment to the leading edge
    • Dow, L.E., Kauffman, J.S., Caddy, J., Zarbalis, K., Peterson, A.S., Jane, S.M., Russell, S.M. & Humbert, P.O. (2007) The tumour-suppressor Scribble dictates cell polarity during directed epithelial migration: Regulation of Rho GTPase recruitment to the leading edge. Oncogene 26, 2272-2282.
    • (2007) Oncogene , vol.26 , pp. 2272-2282
    • Dow, L.E.1    Kauffman, J.S.2    Caddy, J.3    Zarbalis, K.4    Peterson, A.S.5    Jane, S.M.6    Russell, S.M.7    Humbert, P.O.8
  • 12
    • 0033619139 scopus 로고    scopus 로고
    • Oncogenic human papillomavirus E6 proteins target the discs large tumour suppressor for proteasome-mediated degradation
    • Gardiol, D., Kuhne, C., Glaunsinger, B., Lee, S.S., Javier, R. & Banks, L. (1999) Oncogenic human papillomavirus E6 proteins target the discs large tumour suppressor for proteasome-mediated degradation. Oncogene 18, 5487-5496.
    • (1999) Oncogene , vol.18 , pp. 5487-5496
    • Gardiol, D.1    Kuhne, C.2    Glaunsinger, B.3    Lee, S.S.4    Javier, R.5    Banks, L.6
  • 13
    • 33747465415 scopus 로고    scopus 로고
    • Human discs large and scrib are localized at the same regions in colon mucosa and changes in their expression patterns are correlated with loss of tissue architecture during malignant progression
    • Gardiol, D., Zacchi, A., Petrera, F., Stanta, G. & Banks, L. (2006) Human discs large and scrib are localized at the same regions in colon mucosa and changes in their expression patterns are correlated with loss of tissue architecture during malignant progression. Int. J. Cancer 119, 1285-1290.
    • (2006) Int. J. Cancer , vol.119 , pp. 1285-1290
    • Gardiol, D.1    Zacchi, A.2    Petrera, F.3    Stanta, G.4    Banks, L.5
  • 14
    • 33846542414 scopus 로고    scopus 로고
    • Cleavage of MAGI-1, a tight junction PDZ protein, by caspases is an important step for cell-cell detachment in apoptosis
    • Gregorc, U., Ivanova, S., Thomas, M., Guccione, E., Glaunsinger, B., Javier, R., Turk, V., Banks, L. & Turk, B. (2007) Cleavage of MAGI-1, a tight junction PDZ protein, by caspases is an important step for cell-cell detachment in apoptosis. Apoptosis 12, 343-354.
    • (2007) Apoptosis , vol.12 , pp. 343-354
    • Gregorc, U.1    Ivanova, S.2    Thomas, M.3    Guccione, E.4    Glaunsinger, B.5    Javier, R.6    Turk, V.7    Banks, L.8    Turk, B.9
  • 15
    • 26844453344 scopus 로고    scopus 로고
    • hDLG/SAP97, a member of the MAGUK protein family, is a novel caspase target during cell-cell detachment in apoptosis
    • Gregorc, U., Ivanova, S., Thomas, M., Turk, V., Banks, L. & Turk, B. (2005) hDLG/SAP97, a member of the MAGUK protein family, is a novel caspase target during cell-cell detachment in apoptosis. Biol. Chem. 386, 705-710.
    • (2005) Biol. Chem. , vol.386 , pp. 705-710
    • Gregorc, U.1    Ivanova, S.2    Thomas, M.3    Turk, V.4    Banks, L.5    Turk, B.6
  • 16
    • 33845478597 scopus 로고    scopus 로고
    • Regulation of imaginal disc growth by tumor-suppressor genes in Drosophila
    • Hariharan, I.K. & Bilder, D. (2006) Regulation of imaginal disc growth by tumor-suppressor genes in Drosophila. Annu. Rev. Genet. 40, 335-361.
    • (2006) Annu. Rev. Genet. , vol.40 , pp. 335-361
    • Hariharan, I.K.1    Bilder, D.2
  • 17
    • 0038795589 scopus 로고    scopus 로고
    • Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer
    • Humbert, P., Russell, S. & Richardson, H. (2003) Dlg, Scribble and Lgl in cell polarity, cell proliferation and cancer. Bioessays 25, 542-553.
    • (2003) Bioessays , vol.25 , pp. 542-553
    • Humbert, P.1    Russell, S.2    Richardson, H.3
  • 18
    • 0036547417 scopus 로고    scopus 로고
    • Death and anti-death: Tumour resistance to apoptosis
    • Igney, F.H. & Krammer, P.H. (2002) Death and anti-death: Tumour resistance to apoptosis. Nat. Rev. Cancer 2, 277-288.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 277-288
    • Igney, F.H.1    Krammer, P.H.2
  • 19
    • 35848938163 scopus 로고    scopus 로고
    • Cellular localization of MAGI-1 caspase cleavage products and their role in apoptosis
    • Ivanova, S., Repnik, U., Banks, L., Turk, V. & Turk, B. (2007) Cellular localization of MAGI-1 caspase cleavage products and their role in apoptosis. Biol. Chem. 388, 1195-1198.
    • (2007) Biol. Chem. , vol.388 , pp. 1195-1198
    • Ivanova, S.1    Repnik, U.2    Banks, L.3    Turk, V.4    Turk, B.5
  • 20
    • 0030947095 scopus 로고    scopus 로고
    • Programmed cell death in animal development
    • Jacobson, M.D., Weil, M. & Raff, M.C. (1997) Programmed cell death in animal development. Cell 88, 347-354.
    • (1997) Cell , vol.88 , pp. 347-354
    • Jacobson, M.D.1    Weil, M.2    Raff, M.C.3
  • 21
    • 0032546795 scopus 로고    scopus 로고
    • Caspase-3 is required for α-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis
    • Janicke, R.U., Ng, P., Sprengart, M.L. & Porter, A.G. (1998) Caspase-3 is required for α-fodrin cleavage but dispensable for cleavage of other death substrates in apoptosis. J. Biol. Chem. 273, 15540-15545.
    • (1998) J. Biol. Chem. , vol.273 , pp. 15540-15545
    • Janicke, R.U.1    Ng, P.2    Sprengart, M.L.3    Porter, A.G.4
  • 22
    • 1642553460 scopus 로고    scopus 로고
    • To be, or not to be: NF-κB is the answer-role of Rel/NF-κB in the regulation of apoptosis
    • Kucharczak, J., Simmons, M.J., Fan, Y. & Gelinas, C. (2003) To be, or not to be: NF-κB is the answer-role of Rel/NF-κB in the regulation of apoptosis. Oncogene 22, 8961-8982.
    • (2003) Oncogene , vol.22 , pp. 8961-8982
    • Kucharczak, J.1    Simmons, M.J.2    Fan, Y.3    Gelinas, C.4
  • 23
    • 0032536543 scopus 로고    scopus 로고
    • Caspase-mediated cleavage of focal adhesion kinase pp125FAK and disassembly of focal adhesions in human endothelial cell apoptosis
    • Levkau, B., Herren, B., Koyama, H., Ross, R. & Raines, E.W. (1998) Caspase-mediated cleavage of focal adhesion kinase pp125FAK and disassembly of focal adhesions in human endothelial cell apoptosis. J. Exp. Med. 187, 579-586.
    • (1998) J. Exp. Med. , vol.187 , pp. 579-586
    • Levkau, B.1    Herren, B.2    Koyama, H.3    Ross, R.4    Raines, E.W.5
  • 24
    • 21244439157 scopus 로고    scopus 로고
    • hScrib interacts with ZO-2 at the cell-cell junctions of epithelial cells
    • Metais, J.Y., Navarro, C., Santoni, M.J., Audebert, S. & Borg, J.P. (2005) hScrib interacts with ZO-2 at the cell-cell junctions of epithelial cells. FEBS Lett. 579, 3725-3730.
    • (2005) FEBS Lett. , vol.579 , pp. 3725-3730
    • Metais, J.Y.1    Navarro, C.2    Santoni, M.J.3    Audebert, S.4    Borg, J.P.5
  • 26
    • 0033776810 scopus 로고    scopus 로고
    • Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase
    • Nakagawa, S. & Huibregtse, J.M. (2000) Human scribble (Vartul) is targeted for ubiquitin-mediated degradation by the high-risk papillomavirus E6 proteins and the E6AP ubiquitin-protein ligase. Mol. Cell. Biol. 20, 8244-8253.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 8244-8253
    • Nakagawa, S.1    Huibregtse, J.M.2
  • 27
    • 0842329915 scopus 로고    scopus 로고
    • Analysis of the expression and localisation of a LAP protein, human scribble, in the normal and neoplastic epithelium of uterine cervix
    • Nakagawa, S., Yano, T., Nakagawa, K., Takizawa, S., Suzuki, Y., Yasugi, T., Huibregtse, J.M. & Taketani, Y. (2004) Analysis of the expression and localisation of a LAP protein, human scribble, in the normal and neoplastic epithelium of uterine cervix. Br. J. Cancer 90, 194-199.
    • (2004) Br. J. Cancer , vol.90 , pp. 194-199
    • Nakagawa, S.1    Yano, T.2    Nakagawa, K.3    Takizawa, S.4    Suzuki, Y.5    Yasugi, T.6    Huibregtse, J.M.7    Taketani, Y.8
  • 30
    • 33845472291 scopus 로고    scopus 로고
    • Scrib controls Cdc42 localization and activity to promote cell polarization during astrocyte migration
    • Osmani, N., Vitale, N., Borg, J.P. & Etienne-Manneville, S. (2006) Scrib controls Cdc42 localization and activity to promote cell polarization during astrocyte migration. Curr. Biol. 16, 2395-2405.
    • (2006) Curr. Biol. , vol.16 , pp. 2395-2405
    • Osmani, N.1    Vitale, N.2    Borg, J.P.3    Etienne-Manneville, S.4
  • 31
    • 0242666126 scopus 로고    scopus 로고
    • A genetic screen in Drosophila for metastatic behavior
    • Pagliarini, R.A. & Xu, T. (2003) A genetic screen in Drosophila for metastatic behavior. Science 302, 1227-1231.
    • (2003) Science , vol.302 , pp. 1227-1231
    • Pagliarini, R.A.1    Xu, T.2
  • 32
    • 0033634781 scopus 로고    scopus 로고
    • TNF-α signals apoptosis through a bid-dependent conformational change in Bax that is inhibited by E1B 19K
    • Perez, D. & White, E. (2000) TNF-α signals apoptosis through a bid-dependent conformational change in Bax that is inhibited by E1B 19K. Mol. Cell 6, 53-63.
    • (2000) Mol. Cell , vol.6 , pp. 53-63
    • Perez, D.1    White, E.2
  • 33
    • 24144501081 scopus 로고    scopus 로고
    • The tumor suppressor Scrib selectively interacts with specific members of the zyxin family of proteins
    • Petit, M.M., Crombez, K.R., Vervenne, H.B., Weyns, N. & Van de Ven, W.J. (2005a) The tumor suppressor Scrib selectively interacts with specific members of the zyxin family of proteins. FEBS lett. 579, 5061-5068.
    • (2005) FEBS Lett. , vol.579 , pp. 5061-5068
    • Petit, M.M.1    Crombez, K.R.2    Vervenne, H.B.3    Weyns, N.4    Van de Ven, W.J.5
  • 34
    • 22344441238 scopus 로고    scopus 로고
    • The tumor suppressor Scrib interacts with the zyxin-related protein LPP, which shuttles between cell adhesion sites and the nucleus
    • Petit, M.M., Meulemans, S.M., Alen, P., Ayoubi, T.A., Jansen, E. & Van de Ven, W.J. (2005b) The tumor suppressor Scrib interacts with the zyxin-related protein LPP, which shuttles between cell adhesion sites and the nucleus. BMC Cell Biol. 6, 1.
    • (2005) BMC Cell Biol. , vol.6 , pp. 1
    • Petit, M.M.1    Meulemans, S.M.2    Alen, P.3    Ayoubi, T.A.4    Jansen, E.5    Van de Ven, W.J.6
  • 35
    • 0035960736 scopus 로고    scopus 로고
    • An epithelial cell destined for apoptosis signals its neighbors to extrude it by an actin- and myosin-dependent mechanism
    • Rosenblatt, J., Raff, M.C. & Cramer, L.P. (2001) An epithelial cell destined for apoptosis signals its neighbors to extrude it by an actin- and myosin-dependent mechanism. Curr. Biol. 11, 1847-1857.
    • (2001) Curr. Biol. , vol.11 , pp. 1847-1857
    • Rosenblatt, J.1    Raff, M.C.2    Cramer, L.P.3
  • 36
    • 0030918572 scopus 로고    scopus 로고
    • Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2
    • Rudel, T. & Bokoch, G.M. (1997) Membrane and morphological changes in apoptotic cells regulated by caspase-mediated activation of PAK2. Science 276, 1571-1574.
    • (1997) Science , vol.276 , pp. 1571-1574
    • Rudel, T.1    Bokoch, G.M.2
  • 37
    • 0030702084 scopus 로고    scopus 로고
    • Caspases: Intracellular signaling by proteolysis
    • Salvesen, G.S. & Dixit, V.M. (1997) Caspases: Intracellular signaling by proteolysis. Cell 91, 443-446.
    • (1997) Cell , vol.91 , pp. 443-446
    • Salvesen, G.S.1    Dixit, V.M.2
  • 40
    • 0033429233 scopus 로고    scopus 로고
    • Death by design: Mechanism and control of apoptosis
    • Song, Z. & Steller, H. (1999) Death by design: Mechanism and control of apoptosis. Trends Cell Biol. 9, M49-M52.
    • (1999) Trends Cell Biol. , vol.9
    • Song, Z.1    Steller, H.2
  • 41
    • 0034717270 scopus 로고    scopus 로고
    • Apoptosis-induced cleavage of beta-catenin by caspase-3 results in proteolytic fragments with reduced transactivation potential
    • Steinhusen, U., Badock, V., Bauer, A., Behrens, J., Wittman-Liebold, B., Dorken, B. & Bommert, K. (2000) Apoptosis-induced cleavage of beta-catenin by caspase-3 results in proteolytic fragments with reduced transactivation potential. J. Biol. Chem. 275, 16345-16353.
    • (2000) J. Biol. Chem. , vol.275 , pp. 16345-16353
    • Steinhusen, U.1    Badock, V.2    Bauer, A.3    Behrens, J.4    Wittman-Liebold, B.5    Dorken, B.6    Bommert, K.7
  • 43
    • 0028929328 scopus 로고
    • Mechanisms and genes of cellular suicide
    • Steller, H. (1995) Mechanisms and genes of cellular suicide. Science 267, 1445-1449.
    • (1995) Science , vol.267 , pp. 1445-1449
    • Steller, H.1
  • 44
    • 33645132429 scopus 로고    scopus 로고
    • Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coli
    • Takizawa, S., Nagasaka, K., Nakagawa, S., Yano, T., Nakagawa, K., Yasugi, T., Takeuchi, T., Kanda, T., Huibregtse, J.M., Akiyama, T. & Taketani, Y. (2006) Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coli. Genes Cells 11, 453-464.
    • (2006) Genes Cells , vol.11 , pp. 453-464
    • Takizawa, S.1    Nagasaka, K.2    Nakagawa, S.3    Yano, T.4    Nakagawa, K.5    Yasugi, T.6    Takeuchi, T.7    Kanda, T.8    Huibregtse, J.M.9    Akiyama, T.10    Taketani, Y.11
  • 46
    • 0344494510 scopus 로고    scopus 로고
    • Modeling transformation and metastasis in Drosophila
    • Tapon, N. (2003) Modeling transformation and metastasis in Drosophila. Cancer Cell 4, 333-335.
    • (2003) Cancer Cell , vol.4 , pp. 333-335
    • Tapon, N.1
  • 47
    • 0028943734 scopus 로고
    • Apoptosis in the pathogenesis and treatment of disease
    • Thompson, C.B. (1995) Apoptosis in the pathogenesis and treatment of disease. Science 267, 1456-1462.
    • (1995) Science , vol.267 , pp. 1456-1462
    • Thompson, C.B.1
  • 48
  • 49
    • 11244314036 scopus 로고    scopus 로고
    • Domains controlling cell polarity and proliferation in the Drosophila tumor suppressor Scribble
    • Zeitler, J., Hsu, C.P., Dionne, H. & Bilder, D. (2004) Domains controlling cell polarity and proliferation in the Drosophila tumor suppressor Scribble. J. Cell Biol. 167, 1137-1146.
    • (2004) J. Cell Biol. , vol.167 , pp. 1137-1146
    • Zeitler, J.1    Hsu, C.P.2    Dionne, H.3    Bilder, D.4


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