-
1
-
-
0016685233
-
Methods for detecting carcinogens and mutagens with the Salmonella/mammalian microsome mutagenicity test
-
Ames B, McCann J, Yamasuki E. Methods for detecting carcinogens and mutagens with the Salmonella/mammalian microsome mutagenicity test. Mutat Res 1975;31:347-64
-
(1975)
Mutat Res
, vol.31
, pp. 347-364
-
-
Ames, B.1
McCann, J.2
Yamasuki, E.3
-
2
-
-
0035895249
-
Cancer epigenetics takes center stage
-
Feinberg AP. Cancer epigenetics takes center stage. Proc Natl Acad Sci USA 2001;98:392-4
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 392-394
-
-
Feinberg, A.P.1
-
3
-
-
0035012857
-
A review of the genotoxicity of marketed pharmaceuticals
-
Snyder RD, Green JW. A review of the genotoxicity of marketed pharmaceuticals. Mutat Res 2001;88:151-69
-
(2001)
Mutat Res
, vol.88
, pp. 151-169
-
-
Snyder, R.D.1
Green, J.W.2
-
4
-
-
48949118604
-
-
Physicians' Desk Reference, 55th edition. Montvale, NJ: Medical Economics Co. Inc.; 2001
-
Physicians' Desk Reference, 55th edition. Montvale, NJ: Medical Economics Co. Inc.; 2001
-
-
-
-
5
-
-
21544473568
-
Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens I. Sensitivity, specificity and relative predictivity
-
Kirkland D, Aardema M, Henderson L, Muller L. Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens I. Sensitivity, specificity and relative predictivity. Mutat Res 2005;584:1-256
-
(2005)
Mutat Res
, vol.584
, pp. 1-256
-
-
Kirkland, D.1
Aardema, M.2
Henderson, L.3
Muller, L.4
-
6
-
-
33747751533
-
Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens II. Further analysis of mammalian cell results, relative predictivity and tumour profiles
-
Kirkland D, Aardema M, Müller L, Hayashi M. Evaluation of the ability of a battery of three in vitro genotoxicity tests to discriminate rodent carcinogens and non-carcinogens II. Further analysis of mammalian cell results, relative predictivity and tumour profiles. Mutat Res 2006;608:29-42
-
(2006)
Mutat Res
, vol.608
, pp. 29-42
-
-
Kirkland, D.1
Aardema, M.2
Müller, L.3
Hayashi, M.4
-
7
-
-
32544452551
-
An analysis of genetic toxicity, reproductive and developmental toxicity, and carcinogenicity data. I. Identification of carcinogens using surrogate endpoints
-
Matthews EJ, Kruhlak NL, Cimino MC, et al. An analysis of genetic toxicity, reproductive and developmental toxicity, and carcinogenicity data. I. Identification of carcinogens using surrogate endpoints. Regul Toxicol Pharmacol 2006;44:83-96
-
(2006)
Regul Toxicol Pharmacol
, vol.44
, pp. 83-96
-
-
Matthews, E.J.1
Kruhlak, N.L.2
Cimino, M.C.3
-
9
-
-
33847325174
-
How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: Report of an ECVAM Workshop
-
Kirkland D, Pfuhler S, Tweats D, et al. How to reduce false positive results when undertaking in vitro genotoxicity testing and thus avoid unnecessary follow-up animal tests: report of an ECVAM Workshop. Mutat Res 2007;628:31-55
-
(2007)
Mutat Res
, vol.628
, pp. 31-55
-
-
Kirkland, D.1
Pfuhler, S.2
Tweats, D.3
-
10
-
-
34547841639
-
Relevance and follow-up of positive results in in vitro genetic toxicity assays: An ILSI-HESI initiative
-
Thybaud V, Aardema M, Casciano D, et al. Relevance and follow-up of positive results in in vitro genetic toxicity assays: an ILSI-HESI initiative. Mutat Res 2007:633:67-79
-
(2007)
Mutat Res
, vol.633
, pp. 67-79
-
-
Thybaud, V.1
Aardema, M.2
Casciano, D.3
-
11
-
-
33746309471
-
High-specificity and high-sensitivity genotoxicity assessment in a human cell line: Validation of the GreenScreen HC GADD45a-GFP genotoxicity assay
-
Hastwell PW, Chai L, Roberts KJ, et al. High-specificity and high-sensitivity genotoxicity assessment in a human cell line: validation of the GreenScreen HC GADD45a-GFP genotoxicity assay. Mutat Res 2006;607:160-75
-
(2006)
Mutat Res
, vol.607
, pp. 160-175
-
-
Hastwell, P.W.1
Chai, L.2
Roberts, K.J.3
-
12
-
-
1542271923
-
The utility of DNA microarrays for characterizing genotoxicity
-
Newton R, Aardema M, Aubrecht J. The utility of DNA microarrays for characterizing genotoxicity. Environ Health Perspect 2004;112:420-2
-
(2004)
Environ Health Perspect
, vol.112
, pp. 420-422
-
-
Newton, R.1
Aardema, M.2
Aubrecht, J.3
-
13
-
-
33847311846
-
Genetic toxicity assessment: Employing the best science for human safety evaluation. Part I. Early screening for potential human mutagens
-
Jacobson-Kram D, Contrera J. Genetic toxicity assessment: employing the best science for human safety evaluation. Part I. Early screening for potential human mutagens. Toxicol Sci 2007;96:16-20
-
(2007)
Toxicol Sci
, vol.96
, pp. 16-20
-
-
Jacobson-Kram, D.1
Contrera, J.2
-
14
-
-
0027078830
-
Genotoxic-stress-response genes and growth-arrest genes: Gadd, MyD and other genes induced by treatment eliciting growth arrest
-
Fornace AJ Jr, Jackman J, Hollander MC, et al. Genotoxic-stress-response genes and growth-arrest genes: Gadd, MyD and other genes induced by treatment eliciting growth arrest. Ann NY Acad Sci 1992;663:139-53
-
(1992)
Ann NY Acad Sci
, vol.663
, pp. 139-153
-
-
Fornace Jr, A.J.1
Jackman, J.2
Hollander, M.C.3
-
15
-
-
0027435261
-
Analysis of the mammalian Gadd45 gene and its response to DNA damage
-
Hollander MC, Alamo I, Jackman J, et al. Analysis of the mammalian Gadd45 gene and its response to DNA damage. J Biol Chem 1993;268:24385-93
-
(1993)
J Biol Chem
, vol.268
, pp. 24385-24393
-
-
Hollander, M.C.1
Alamo, I.2
Jackman, J.3
-
16
-
-
0033828761
-
Estimate of the mutation rate per nucleotide in humans
-
Nachman MW, Crowell SL. Estimate of the mutation rate per nucleotide in humans. Genetics 2000;156:297-304
-
(2000)
Genetics
, vol.156
, pp. 297-304
-
-
Nachman, M.W.1
Crowell, S.L.2
-
17
-
-
0037129179
-
Fluorescence polarization discriminates green fluorescent protein from interfering autofluorescence in a microplate assay for genotoxicity
-
Knight AW, Goddard NJ, Billinton N, et al. Fluorescence polarization discriminates green fluorescent protein from interfering autofluorescence in a microplate assay for genotoxicity. J Biochem Biophys Methods 2002;51:165-77
-
(2002)
J Biochem Biophys Methods
, vol.51
, pp. 165-177
-
-
Knight, A.W.1
Goddard, N.J.2
Billinton, N.3
-
18
-
-
36049046631
-
An analysis of results from 305 compounds tested with the yeast RAD54-GFP genotoxicity assay (GreenScreen GC), including relative predictivity of regulatory tests and rodent carcinogenesis and performance with autofluorescent and coloured compounds
-
Knight AW, Billinton N, Cahill PA, et al. An analysis of results from 305 compounds tested with the yeast RAD54-GFP genotoxicity assay (GreenScreen GC), including relative predictivity of regulatory tests and rodent carcinogenesis and performance with autofluorescent and coloured compounds. Mutagenesis 2007;22:409-16
-
(2007)
Mutagenesis
, vol.22
, pp. 409-416
-
-
Knight, A.W.1
Billinton, N.2
Cahill, P.A.3
-
19
-
-
19944430250
-
A modular approach to the ECVAM principles on test validity
-
Hartung T, Bremer S, Casati S, et al. A modular approach to the ECVAM principles on test validity. Altern Lab Anim 2004;32:467-72
-
(2004)
Altern Lab Anim
, vol.32
, pp. 467-472
-
-
Hartung, T.1
Bremer, S.2
Casati, S.3
-
20
-
-
49649106099
-
Interlaboratory assessment of the GreenScreen HC GADD45a-GFP genotoxicity screening assay: An enabling study for independent validation as an alternative method
-
In press. Epub doi:10.1016/ j.mrgentox.2008.02.011
-
Billinton N, Hastwell PW, Beerens D, et al. Interlaboratory assessment of the GreenScreen HC GADD45a-GFP genotoxicity screening assay: an enabling study for independent validation as an alternative method. Mutat Res Genet Toxicol Environ Mutagen 2008; In press. Epub doi:10.1016/ j.mrgentox.2008.02.011
-
(2008)
Mutat Res Genet Toxicol Environ Mutagen
-
-
Billinton, N.1
Hastwell, P.W.2
Beerens, D.3
-
21
-
-
48949118606
-
The carcinogenic potency project
-
Gold LS. The carcinogenic potency project. 2007. Available from: htrp:// potency.berkeley.edu/cpdb.html
-
(2007)
Available from: Htrp
-
-
Gold, L.S.1
-
22
-
-
48949118607
-
-
Gold LS, Slone TH, Manley NB, Ames BN. Misconceptions about the causes of cancer. Risk Controversy Series 3. Vancouver, BC: The Fraser Institute, Centre for Studies in Risk, Regulation and Environment; 2002
-
Gold LS, Slone TH, Manley NB, Ames BN. Misconceptions about the causes of cancer. Risk Controversy Series 3. Vancouver, BC: The Fraser Institute, Centre for Studies in Risk, Regulation and Environment; 2002
-
-
-
-
23
-
-
0037298765
-
Comparison of cancer risk estimates based on a variety of risk assessment methodologies
-
Gold LS, David W, Gaylor DW, Slone TH. Comparison of cancer risk estimates based on a variety of risk assessment methodologies. Regul Toxicol Pharmacol 2003;37:45-53
-
(2003)
Regul Toxicol Pharmacol
, vol.37
, pp. 45-53
-
-
Gold, L.S.1
David, W.2
Gaylor, D.W.3
Slone, T.H.4
-
25
-
-
0029897453
-
The rodent bone marrow micronucleus assay: Contrast between its sensitiviy to human carcinogens and its sensitivity to NTP rodent carcinogens
-
Ashby J, Tinwell H. The rodent bone marrow micronucleus assay: contrast between its sensitiviy to human carcinogens and its sensitivity to NTP rodent carcinogens. Mutat Res 1996;352:181-4
-
(1996)
Mutat Res
, vol.352
, pp. 181-184
-
-
Ashby, J.1
Tinwell, H.2
-
26
-
-
0030871409
-
-
Morita T, Asano N, Awogi T, et al. Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (Groups 1, 2A and 2B): the summary report of the 6th collaborative study by CSGMT/JEMS. Mutat Res389:3-122
-
Morita T, Asano N, Awogi T, et al. Evaluation of the rodent micronucleus assay in the screening of IARC carcinogens (Groups 1, 2A and 2B): the summary report of the 6th collaborative study by CSGMT/JEMS. Mutat Res389:3-122
-
-
-
-
27
-
-
33846186786
-
Report of the IWGT working group on strategies and interpretation of regulatory in vivo tests. I. Increases in micronucleated bone marrow cells in rodents that do not indicate genotoxic hazards
-
Tweats DJ, Blakey D, Heflich RH, et al. Report of the IWGT working group on strategies and interpretation of regulatory in vivo tests. I. Increases in micronucleated bone marrow cells in rodents that do not indicate genotoxic hazards. Mutat Res 2007;627:78-91
-
(2007)
Mutat Res
, vol.627
, pp. 78-91
-
-
Tweats, D.J.1
Blakey, D.2
Heflich, R.H.3
-
28
-
-
48949118609
-
-
Jagger C, Tate M, Cahill P, et al. Genotoxicity assessment using a GADD45a-GFP reporter assay in a p53 competent human cell host: metabolic activation, flow cytometry and data update. Poster, Environmental Mutagen Society Annual Meeting; 2006
-
Jagger C, Tate M, Cahill P, et al. Genotoxicity assessment using a GADD45a-GFP reporter assay in a p53 competent human cell host: metabolic activation, flow cytometry and data update. Poster, Environmental Mutagen Society Annual Meeting; 2006
-
-
-
-
29
-
-
33846127217
-
Strategy for genotoxicity testing: Metabolic considerations
-
Ku WW, Bigger A, Brambilla G, et al. Strategy for genotoxicity testing: metabolic considerations. Mutat Res 2007;627:59-77
-
(2007)
Mutat Res
, vol.627
, pp. 59-77
-
-
Ku, W.W.1
Bigger, A.2
Brambilla, G.3
-
30
-
-
1242339717
-
Assessment of the performance of the Ames II™ assay: A collaborative study with 19 coded compounds
-
Flückiger-Isler S, Baumeister M, Braun K, et al. Assessment of the performance of the Ames II™ assay: a collaborative study with 19 coded compounds. Mutat Res 2004;558:181-97
-
(2004)
Mutat Res
, vol.558
, pp. 181-197
-
-
Flückiger-Isler, S.1
Baumeister, M.2
Braun, K.3
-
31
-
-
0025951750
-
A microplate version of the SOS/ umu-test for rapid detection of genotoxins and genotoxic potentials of environmental samples
-
Reifferscheid G, Heil J, Oda Y, Zahn RK. A microplate version of the SOS/ umu-test for rapid detection of genotoxins and genotoxic potentials of environmental samples. Mutat Res 1991;253:215-22
-
(1991)
Mutat Res
, vol.253
, pp. 215-222
-
-
Reifferscheid, G.1
Heil, J.2
Oda, Y.3
Zahn, R.K.4
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