Microwave-induced nucleophilic [18F]fluorination on aromatic rings: Synthesis and effect of halogen on [18F]fluoride substitution of meta-halo (F, Cl, Br, I)-benzonitrile derivatives

Applied Radiation and Isotopes

Volumn 66, Issue 10, 2008, Pages 1396-1402

  Guo, Ning ^a   Alagille, David ^b   Tamagnan, Gilles ^b   Price, Ronald R ^a   Baldwin, Ronald M ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Molecular Neuroimaging   (United States)

Author keywords

Fluorine 18; Microwave; Organic synthesis; PET tracer; Radiolabeling; Substituent effect

Indexed keywords

AROMATIC COMPOUNDS; ARSENIC COMPOUNDS; MICROWAVES;

AROMATIC NUCLEOPHILIC SUBSTITUTION; FLUORINE-18; MICROWAVE; MICROWAVE SYSTEMS; MODEL COMPOUNDS; ORGANIC SYNTHESIS; PET TRACER; RADIOLABELING; SINGLE MODES; SUBSTITUENT EFFECT;

CHLORINE COMPOUNDS;

AROMATIC COMPOUND; BENZONITRILE; BROMINE; CHLORINE; FLUORINE 18; HALOGEN; IODINE;

ARTICLE; DEAMINATION; FLUORINATION; HALOGENATION; ISOTOPE LABELING; MICROWAVE IRRADIATION; PRIORITY JOURNAL; RADIOCHEMISTRY;

FLUORINE RADIOISOTOPES; HALOGENS; ISOTOPE LABELING; MICROWAVES; POLYCYCLIC HYDROCARBONS, AROMATIC;

EID: 48849113872     PISSN: 09698043     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.apradiso.2008.03.003     Document Type: Article

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