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Volumn 124, Issue 50, 2002, Pages 14844-14845

Copper-catalyzed halogen exchange in aryl halides: An aromatic finkelstein reaction

Author keywords

[No Author keywords available]

Indexed keywords

COPPER; HALIDE; IODINE DERIVATIVE;

EID: 0037132666     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja028865v     Document Type: Article
Times cited : (403)

References (33)
  • 16
    • 0345329013 scopus 로고
    • (a) Lindley, J. Tetrahedron 1984, 40, 1433. For practical applications, see:
    • (1984) Tetrahedron , vol.40 , pp. 1433
    • Lindley, J.1
  • 30
    • 0012108629 scopus 로고    scopus 로고
    • note
    • The following conversions of 5-bromo-m-xylene into 5-iodo-m-xylene were observed after 22 h at 110 °C in dioxane using 2.0 equiv of NaI, 5.0 mol % of CuI, and 10 mol % of a ligand: 1a, 77%; 1b, 99.3%; 2a, 73%; 2b, 98%; 3, 72%; 1,10-phenanthroline, 6%; no ligand, <0.1%.
  • 31
    • 0012147082 scopus 로고    scopus 로고
    • note
    • Aryl chlorides react more slowly than aryl bromides. A 35% conversion (GC) of 4-chlorotoluene into 4-iodotoluene was observed after 24 h at 130 °C.
  • 32
    • 0012184368 scopus 로고    scopus 로고
    • note
    • In a control experiment, only 1% yield (by GC) of 4o was observed if ligand 3 was omitted.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.