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30
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0012108629
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note
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The following conversions of 5-bromo-m-xylene into 5-iodo-m-xylene were observed after 22 h at 110 °C in dioxane using 2.0 equiv of NaI, 5.0 mol % of CuI, and 10 mol % of a ligand: 1a, 77%; 1b, 99.3%; 2a, 73%; 2b, 98%; 3, 72%; 1,10-phenanthroline, 6%; no ligand, <0.1%.
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31
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0012147082
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note
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Aryl chlorides react more slowly than aryl bromides. A 35% conversion (GC) of 4-chlorotoluene into 4-iodotoluene was observed after 24 h at 130 °C.
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32
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0012184368
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note
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In a control experiment, only 1% yield (by GC) of 4o was observed if ligand 3 was omitted.
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