Fast and easy halide exchange in aryl halides

Synlett

Volumn , Issue 8, 2003, Pages 1145-1148

  Arvela, Riina K ^a   Leadbeater, Nicholas E ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Aryl halide; Microwave; Nickel; Water

Indexed keywords

BROMIDE; CHLORIDE; HALIDE; IODIDE; NICKEL; WATER;

AIR; ARTICLE; HEATING; MICROWAVE RADIATION; REACTION ANALYSIS; TEMPERATURE DEPENDENCE;

EID: 0038053161     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2003-39887     Document Type: Article

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25. 2O, 0%, PEG-400, 8%, DME, 0%.
26. CAUTION: The DMF is heated above its boiling point so all necessary precautions should be taken when performing such experiments. Vessels designed to withhold elevated pressures must be used. The microwave apparatus used here incorporates a protective metal cage around the microwave vessel in case of explosion. After completion of an experiment, the vessel must be allowed to cool to a temperature below the boiling point of the solvent before removal from the microwave cavity and opening to the atmosphere.
27. CAUTION: A blast shield should be in place and vessels designed to withhold elevated pressures must be used. After completion of an experiment, the vessel must be allowed to cool before opening to the atmosphere.