Fibroblast growth factor-2 regulates expression of osteopontin in periodontal ligament cells

Journal of Cellular Physiology

Volumn 216, Issue 3, 2008, Pages 640-650

  Terashima, Yoshimitsu ^a   Shimabukuro, Yoshio ^a   Terashima, Hiroaki ^a   Ozasa, Masao ^a   Terakura, Mami ^a   Ikezawa, Kazuhiko ^a   Hashikawa, Tomoko ^a   Takedachi, Masahide ^a   Oohara, Hiroyuki ^a   Yamada, Satoru ^a   Murakami, Shinya ^a  

^a OSAKA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ACTIN; COLLAGEN TYPE 1; FIBROBLAST GROWTH FACTOR 2; FOSCARNET; MESSENGER RNA; OSTEOCALCIN; OSTEONECTIN; OSTEOPONTIN; PHOSPHATE; TRANSCRIPTION FACTOR RUNX2;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; EXTRACELLULAR MATRIX; GENE EXPRESSION; IMMUNOCYTOCHEMISTRY; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; PERIODONTAL LIGAMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; SUPERNATANT; TISSUE REGENERATION; UPREGULATION;

ANIMALS; APOPTOSIS; CELL DIFFERENTIATION; CELL MEMBRANE; CELL SURVIVAL; CELLS, CULTURED; EXTRACELLULAR MATRIX; FIBROBLAST GROWTH FACTOR 2; GENE EXPRESSION REGULATION; MICE; OSTEOPONTIN; PERIODONTAL LIGAMENT; PHOSPHATES;

EID: 48749122706     PISSN: 00219541     EISSN: None     Source Type: Journal    
DOI: 10.1002/jcp.21443     Document Type: Article

References (78)

1. Aeschlimann D, Wetterwald A, Fleisch H, Paulsson M. 1993. Expression of tissue transglutaminase in skeletal tissues correlates with events of terminal differentiation of chondrocytes. J Cell Biol 120:1461-1470.
2. Aeschlimann D, Kaupp O, Paulsson M. 1995. Transglutaminase-catalyzed matrix cross-linking in differentiating cartilage: Identification of osteonectin as a major glutaminyl substrate. J Cell Biol 129:881-892.
3. Agnholt J, Kelsen J, Schack L, Hvas CL, Dahlerup JF, Sørensen ES. 2007. Osteopontin, a protein with cytokine-like properties, is associated with inflammation in Crohn's disease. Scand J Immunol 65:453-460.
4. Ashkar S, Weber GF, Panoutsakopoulou V, Sanchirico ME, Jansson M, Zawaideh S, Rittling SR, Denhardt DT, Glimcher MJ, Cantor H. 2000. Eta-1 (osteopontin): An early component of type-1 (cell-mediated) immunity. Science 287:860-864.
5. Beck GRJ, Moran E, Knecht N. 2003. Inorganic phosphate regulates multiple genes during osteoblast differentiation, including Nrf2. Exp Cell Res 288:288-300.
6. Bellows CG, Heersche JN, Aubin JE. 1992. Inorganic phosphate added exogenously or released from beta-glycerophosphate initiates mineralization of osteoid nodules in vitro. Bone Miner 17:15-29.
7. Bendeck MP, Irvin C, Reidy M, Smith L, Mulholland D, Horton M, Giachelli CM. 2000. Smooth muscle cell matrix metalloproteinase production is stimulated via alpha(v)beta(3) integrin. Arterioscler Thromb Vasc Biol 20:1467-1472.
8. Bessey OA, Lowry OH. 1946. A method for rapid determination of alkaline phosphatase with five cubic millimeters of serum. J Biol Chem 164:321-329.
9. Boskey AL, Maresca M, Ullrich W, Doty SB, Butler WT, Prince CW. 1993. Osteopontin-hydroxyapatite interactions in vitro: Inhibition of hydroxyapatite formation and growth in a gelatin-gel. Bone Miner 22:147-159.
10. Castellone MD, Celetti A, Guarino V, Cirafici AM, Basolo F, Giannini R, Medico E, Kruhoffer M, Orntoft TF, Curcio F, Fusco A, Melillo RM, Santoro M. 2004. Autocrine stimulation by osteopontin plays a pivotal role in the expression of the mitogenic and invasive phenotype of RET/PTC-transformed thyroid cells. Oncogene 23:2188-2196.
11. Chellaiah MA, Hruska KA. 2003. The integrin alpha(v)beta(3) and CD44 regulate the actions of osteopontin on osteoclast motility. Calcif Tissue Int 72:197-205.
12. Chung CH, Golub EE, Forbes ETT, Shapiro IM. 1992. Mechanism of action of beta-glycerophosphate on bone cell mineralization. Calcif Tissue Int 51:305-311.
13. Dahl LK. 1952. A simple and sensitive histochemical method for calcium. Proc Soc Exp Biol Med 80:474-479.
14. Debiais F, Lefevre G, Lemonnier J, Le Mee S, Lasmoles F, Mascarelli F, Marie PJ. 2004. Fibroblast growth factor-2 induces osteoblast survival through a phosphatidylinositol 3-kinase-dependent, -beta-catenin-independent signaling pathway. Exp Cell Res 297:235-246.
15. Denhardt DT, Guo XJ. 1993. Osteopontin: A protein with diverse functions. FASEB J 7:1475-1482.
16. Denhardt DT, Noda M. 1998. Osteopontin expression and function: Role in bone remodeling. J Cell Biochem Suppl 30-31:92-102 (Review).
17. Denhardt DT, Giachelli CM, Rittling SR. 2001a. Role of osteopontin in cellular signaling and toxicant injury. Annu Rev Pharmacol Toxicol 41:723-749.
18. Denhardt DT, Noda M, O'Regan AW, Pavlin D, Berman JS. 2001b. Osteopontin as a means to cope with environmental insults: Regulation of inflammation, tissue remodeling, and cell survival. J Clin Invest 107:1055-1061.
19. Foster BL, Nociti FHJ, Swanson EC, Matsa-Dunn D, Berry JE, Cupp CJ, Zhang P, Somerman MJ. 2006. Regulation of cementoblast gene expression by inorganic phosphate in vitro. Calcif Tissue Int 78:103-112.
20. Giachelli CM, Pichler R, Lombardi D, Denhardt DT, Alpers CE, Schwartz SM, Johnson RJ. 1994. Osteopontin expression in angiotensin II-induced tubulointerstitial nephritis. Kidney Int 45:515-524.
21. Glimcher MJ. 1989. Mechanism of calcification: Role of collagen fibrils and collagen-phosphoprotein complexes in vitro and in vivo. Anat Rec 224:139-153.
22. Guo H, Cai CQ, Schroeder RA, Kuo PC. 2001. Osteopontin is a negative feedback regulator of nitric oxide synthesis in murine macrophages. J Immunol 166:1079-1086.
23. Hakki SS, Nohutcu RM, Hakki EE, Berry JE, Akkaya MS, Somerman MJ. 2005. Dexamethasone and basic-fibroblast growth factor regulate markers of mineralization in cementoblasts in vitro. J Periodontol 76:1550-1558.
24. Hashimoto M, Koda M, Ino H, Murakami M, Yamazaki M, Moriya H. 2003. Upregulation of osteopontin expression in rat spinal cord microglia after traumatic injury. J Neurotrauma 20:287-296.
25. Heath DJ, Downes S, Verderio E, Griffin M. 2001. Characterization of tissue transglutaminase in human osteoblast-like cells. J Bone Miner Res 16:1477-1485.
26. Hijiya N, Setoguchi M, Matsuura K, Higuchi Y, Akizuki S, Yamamoto S. 1994. Cloning and characterization of the human osteopontin gene and its promoter. Biochem J 303:255-262.
27. Ishijima M, Tsuji K, Rittling SR, Yamashita T, Kurosawa H, Denhardt DT, Nifuji A, Ezura Y, Noda M. 2007. Osteopontin is required for mechanical stress-dependent signals to bone marrow cells. J Endocrinol 193:235-243.
28. Jono S, Peinado C, Giachelli CM. 2000. Phosphorylation of osteopontin is required for inhibition of vascular smooth muscle cell calcification. J Biol Chem 275:20197-20203.
29. Kaartinen MT, Pirhonen A, Linnala-Kankkunen A, Maenpaa PH. 1999. Cross-linking of osteopontin by tissue transglutaminase increases its collagen binding properties. J Biol Chem 274:1729-1735.
30. Khan SA, Lopez-Chua CA, Zhang J, Fisher LW, Sorensen ES, Denhardt DT. 2002. Soluble osteopontin inhibits apoptosis of adherent endothelial cells deprived of growth factors. J Cell Biochem 85:728-736.
31. Kim HJ, Lee MH, Park HS, Park MH, Lee SW, Kim SY, Choi JY, Shin HI, Kim HJ, Ryoo HM. 2003. Erk pathway and activator protein 1 play crucial roles in FGF2-stimulated premature cranial suture closure. Dev Dyn 227:335-346.
32. Labarca C, Paigen K. 1980. A simple, rapid, and sensitive DNA assay procedure. Anal Biochem 102:344-352.
33. Lao M, Marino V, Bartold PM. 2006. Immunohistochemical study of bone sialoprotein and osteopontin in healthy and diseased root surfaces. J Periodontol 77:1665-1673.
34. Leali D, Dell'Era P, Stabile H, Sennino B, Chambers AF, Naldini A, Sozzani S, Nico B, Ribatti D, Presta M. 2003. Osteopontin (Eta-1) and fibroblast growth factor-2 cross-talk in angiogenesis. J Immunol 171:1085-1093.
35. Li G, Chen YF, Kelpke SS, Oparil S, Thompson JA. 2000. Estrogen attenuates integrin-beta(3)-dependent adventitial fibroblast migration after inhibition of osteopontin production in vascular smooth muscle cells. Circulation 101:2949-2955.
36. Liaw L, Almeida M, Hart CE, Schwartz SM, Giachelli CM. 1994. Osteopontin promotes vascular cell adhesion and spreading and is chemotactic for smooth muscle cells in vitro. Circ Res 74:214-224.
37. Liaw L, Birk DE, Ballas CB, Whitsitt JS, Davidson JM, Hogan BL. 1998. Altered wound healing in mice lacking a functional osteopontin gene (spp1). J Clin Invest 101:1468-1478.
38. Lin YH, Yang-Yen HF. 2001. The osteopontin-CD44 survival signal involves activation of the phosphatidylinositol 3-kinase/Akt signaling pathway. J Biol Chem 276:46024-46030.
39. Lin YH, Huang CJ, Chao JR, Chen ST, Lee SF, Yen JJ, Yang-Yen HF. 2000. Coupling of osteopontin and its cell surface receptor CD44 to the cell survival response elicited by interleukin-3 or granulocyte-macrophage colony-stimulating factor. Mol Cell Biol 20:2734-2742.
40. MacNeil RL, Berry J, D'Errico J, Strayhorn C, Piotrowski B, Somerman MJ. 1995a. Role of two mineral-associated adhesion molecules, osteopontin and bone sialoprotein, during cementogenesis. Connect Tissue Res 33:1-7 (Review).
41. MacNeil RL, Berry J, D'Errico J, Strayhorn C, Somerman MJ. 1995b. Localization and expression of osteopontin in mineralized and nonmineralized tissues of the periodontium. Ann N Y Acad Sci 760:166-176 (Review).
42. McKee MD, Nanci A. 1996. Secretion of Osteopontin by macrophages and its accumulation at tissue surfaces during wound healing in mineralized tissues: A potential require ment for macrophage adhesion and phagocytosis. Anat Rec 245:394-409.
43. Mukherjee BB, Nemir M, Beninati S, Cordella-Miele E, Singh K, Chackalaparampil I, Shanmugam V, DeVouge MW, Mukherjee AB. 1995. Interaction of osteopontin with fibronectin and other extracellular matrix molecules. Ann N Y Acad Sci 21:201-212.
44. Murakami S, Takayama S, Ikezawa K, Shimabukuro Y, Kitamura M, Nozaki T, Terashima A, Asano T, Okada H. 1999. Regeneration of periodontal tissues by basic fibroblast growth factor. J Periodontal Res 34:425-430.
45. Murakami S, Takayama S, Kitamura M, Shimabukuro Y, Yanagi K, Ikezawa K, Saho T, Nozaki T, Okada H. 2003. Recombinant human basic fibroblast growth factor (bFGF) stimulates periodontal regeneration in class II furcation defects created in beagle dogs. J Periodontal Res 38:97-103.
46. Murry CE, Giachelli CM, Schwartz SM, Vracko R. 1994. Macrophages express osteopontin during repair of myocardial necrosis. Am J Pathol 145:1450-1462.
47. Naldini A, Leali D, Pucci A, Morena E, Carraro F, Nico B, Ribatti D, Presta M. 2006. IL-1 beta mediates the proangiogenic activity of osteopontin-activated human monocytes. J Immunol 177:4267-4270.
48. Nau GJ, Guilfoile P, Chupp GL, Berman JS, Kim SJ, Kornfeld H, Young RA. 1997. A chemoattractant cytokine associated with granulomas in tuberculosis and silicosis. Proc Natl Acad Sci USA 94:6414-6419.
49. Nau GJ, Chupp GL, Emile JF, Jouanguy E, Berman JS, Casanova JL, Young RA. 2000. Osteopontin expression correlates with clinical outcome in patients with mycobacterial infection. AmJ Pathol 157:37-42.
50. Noiri E, Dickman K, Miller F, Romanov G, Romanov VI, Shaw R, Chambers AF, Rittling SR, Denhardt DT, Goligorsky MS. 1999. Reduced tolerance to acute renal ischemia in mice with a targeted disruption of the osteopontin gene. Kidney Int 56:74-82.
51. O'Brien ER, Garvin MR, Stewart DK, Hinohara T, Simpson JB, Schwartz SM, Giachelli CM. 1994. Osteopontin is synthesized by macrophage, smooth muscle, and endothelial cells in primary and restenotic human coronary atherosclerotic plaques. Arterioscler Thromb 14:1648-1656.
52. Ophascharoensuk V, Giachelli CM, Gordon K, Hughes J, Pichler R, Brown P, Liaw L, Schmidt R, Shankland SJ, Alpers CE, Couser WG, Johnson RJ. 1999. Obstructive uropathy in the mouse: Role of osteopontin in interstitial fibrosis and apoptosis. Kidney Int 56:571-580.
53. O'Regan A, Berman JS. 2000. Osteopontin: A key cytokine in cell-mediated and granulomatous inflammation. Int J Exp Pathol 81:373-390.
54. O'Regan AW, Chupp GL, Lowry JA, Goetschkes M, Mulligan N, Berman JS. 1999. Osteopontin is associated with T cells in sarcoid granulomas and has T cell adhesive and cytokine-like properties in vitro. J Immunol 162:1024-1031.
55. Pampena DA, Robertson KA, Litvinova O, Lajoie G, Goldberg HA, Hunter GK. 2004. Inhibition of hydroxyapatite formation by osteopontin phosphopeptides. Biochem J 378:1083-1087.
56. Patarca R, Freeman GJ, Singh RP, Wei FY, Durfee T, Blattner F, Regnier DC, Kozak CA, Mock BA, Morse HCI, Jerrells TR, Cantor H. 1989. Structural and functional studies of the early T lymphocyte activation 1 (Eta-1) gene. Definition of a novel T cell-dependent response associated with genetic resistance to bacterial infection. J Exp Med 170:145-161.
57. Persy VP, Verhulst A, Ysebaert DK, De Greef KE, De Broe ME. 2003. Reduced postishemic macrophage infiltration and interstitial fibrosis in osteopontin knockout mice. Kidney Int 63:543-553.
58. Rajamannan NM, Nealis TB, Subramaniam M, Pandya S, Stock SR, Ignatiev CI, Sebo JT, Rosengart TK, Edwards WD, McCarthy PM, Bonow RO, Spelsberg TC. 2005. Calcified rheumatic valve neoangiogenesis is associated with vascular endothelial growth factor expression and osteoblast-1 ike bone formation. Circulation 111:3296-3301.
59. Rittling SR, Chen Y, Feng F, Wu Y. 2002. Tumor-derived osteopontin is soluble, not matrix associated. J Biol Chem 277:9175-9182.
60. Rogers SA, Padanilam BJ, Hruska KA, Giachelli CM, Hammerman MR. 1997. Metanephric osteopontin regulates nephrogenesis in vitro. Am J Physiol 272:F469-F476.
61. Rollo EE, Laskin DL, Denhardt DT. 1996. Osteopontin inhibits nitric oxide production and cytotoxicity by activated R AW264.7 macrophages. J Leukoc Biol 60:397.
62. Saavedra RA. 1994. The roles of autophosphorylation and phosphorylation in the life of osteopontin. Bioessays 16:913-918.
63. Scatena M, Almeida M, Chaisson ML, Fausto N, Nicosia RF, Giachelli CM. 1998. NF-kappaB mediates alphavbeta3 integrin-induced endothelial cell survival. J Cell Biol 141:1083-1093.
64. Senger DR, Asch BB, Smith BD, Perruzzi CA, Dvorak HF. 1983. A secreted phosphoprotein marker for neoplastic transformation of both epithelial and fibroblastic cells. Nature 302:714-715.
65. Senger DR, Ledbetter SR, Claffey KP, Papadopoulos-Sergiou A, Peruzzi CA, Detmar M. 1996. Stimulation of endothelial cell migration by vascular permeability factor/vascular endothelial growth factor through cooperative mechanisms involving the alphavbeta3 integrin, osteopontin, and thrombin. Am J Pathol 149:293-305.
66. Seo BM, Miura M, Gronthos S, Bartold PM, Batouli S, Brahim J, Young M, Robey PG, Wang CY, Shi S. 2004. Investigation of multipotent postnatal stem cells from human periodontal ligament. Lancet 364:149-155.
67. Shimabukuro Y, Ichikawa T, Takayama S, Yamada S, Takedachi M, Terakura M, Hashikawa T, Murakami S. 2005. Fibroblast growth factor-2 regulates the synthesis of hyaluronan by human periodontal ligament cells. J Cell Physiol 203:557-563.
68. Singh K, DeVouge MW, Mukherjee BB. 1990. Physiological properties and differential glycosylation of phosphorylated and nonphosphorylated forms of osteopontin secreted by normal rat kidney cells. J Biol Chem 265:18696-18701.
69. Sorensen ES, Petersen TE. 1995. Phosphorylation, glycosylation, and transglutaminase sites in bovine osteopontin. Ann N Y Acad Sci 760:363-366.
70. Srivatsa SS, Harrity PJ, Maercklein PB, Kleppe L, Veinot J, Edwards WD, Johnson CM, Fitzpatrick LA. 1997. Increased cellular expression of matrix proteins that regulate mineralization is associated with calcification of native human and porcine xenograft bioprosthetic heart valves. J Clin Invest 99:996-1009.
71. Takahashi F, Takahashi K, Okazaki T, Maeda K, Ienaga H, Maeda M, Kon S, Uede T, Fukuchi Y. 2001. Role of osteopontin in the pathogenesis of bleomycin-induced pulmonary fibrosis. Am J Respir Cell Mol Biol 24:264-271.
72. Takayama S, Murakami S, Miki Y, Ikezawa K, Tasaka S, Terashima A, Asano T, Okada H. 1997. Effects of basic fibroblast growth factor on human periodontal ligament cells. J Periodontal Res 32:667-675.
73. Takayama S, Murakami S, Shimabukuro Y, Kitamura M, Okada H. 2001. Periodontal regeneration by FGF-2 (bFGF) in primate models. J Dent Res 80:2075-2079.
74. Weintraub AS, Schnapp LM, Lin X, Taubman MB. 2000. Osteopontin deficiency in rat vascular smooth muscle cells is associated with an inability to adhere to collagen and increased apoptosis. Lab Invest 80:1603-1615.
75. Xiao G, Jiang D, Gopalakrishnan R, Franceschi RT. 2002. Fibroblast growth factor 2 induction of the osteocalcin gene requires MAPK activity and phosphorylation of the osteoblast: transcription factor, Cbfa1/Runx2. J Biol Chem 277:36181-36187.
76. Yamada S, Tomoeda M, Ozawa Y, Yoneda S, Terashima Y, Ikezawa K, Ikegawa S, Saito M, Toyosawa S, Murakami S. 2007. PLAP-1/asporin: A novel negative regulator of periodontal ligament mineralization. J Biol Chem 282:23070-23080.
77. Zohar R, Lee W, Arora P, Cheifetz S, McCulloch C, Sodek J. 1997. Single cell analysis of intracellular osteopontin in osteogenic cultures of fetal rat calvarial cells. J Cell Physiol 170:88-100.
78. Zohar R, Suzuki N, Suzuki K, Arora P, Glogauer M, McCulloch CA, Sodek J. 2000. Intracellular osteopontin is an integral component of the CD44-ERM complex involved in cell migration. J Cell Physiol 184:118-130.