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Volumn 3, Issue 4, 2008, Pages 385-397

Role of lipoprotein lipase in triglyceride metabolism: Potential therapeutic target

Author keywords

Lipoprotein; Lipoprotein deficiency; Primary hypertriglyceridemia; Therapy; Triglycerides

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; 4 (4 BROMO 2 CYANOPHENYLCARBAMOYL)BENZYLPHOSPHONIC ACID DIETHYL ESTER; ANTILIPEMIC AGENT; ANTISENSE OLIGONUCLEOTIDE; APOLIPOPROTEIN B; APOLIPOPROTEIN B100; APOLIPOPROTEIN C3; FIBRIC ACID DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; LIPOPROTEIN LIPASE; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MEDIUM CHAIN TRIACYLGLYCEROL; MIPOMERSEN; N 1886; OMEGA 3 FATTY ACID; PARVOVIRUS VECTOR; PIOGLITAZONE; ROSIGLITAZONE; TRIACYLGLYCEROL; VERY LOW DENSITY LIPOPROTEIN;

EID: 48749100753     PISSN: 17460875     EISSN: None     Source Type: Journal    
DOI: 10.2217/17460875.3.4.385     Document Type: Review
Times cited : (21)

References (108)
  • 1
    • 0029838433 scopus 로고    scopus 로고
    • Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: A meta-analyiis ofpopulation-based prospective studies
    • Hokanson JE, Austin MA: Plasma triglyceride level is a risk factor for cardiovascular disease independent of high-density lipoprotein cholesterol level: a meta-analyiis ofpopulation-based prospective studies. J. Cardiovasc. Risk 3(2),213-219 (1996).
    • (1996) J. Cardiovasc. Risk , vol.3 , Issue.2 , pp. 213-219
    • Hokanson, J.E.1    Austin, M.A.2
  • 2
    • 0032567917 scopus 로고    scopus 로고
    • Krauss RM: Atherogenicity of triglyceriderich lipoproteins. Am. J. Cardiol. 81(4A), 13B-17B (1998).
    • Krauss RM: Atherogenicity of triglyceriderich lipoproteins. Am. J. Cardiol. 81(4A), 13B-17B (1998).
  • 4
    • 0025118667 scopus 로고
    • Artherogenis lipoprotein phenotype. A proposed genetic marker for coronary heart disease risk
    • Austin MA, King MC, Vranizan W, Krauss RM: Artherogenis lipoprotein phenotype. A proposed genetic marker for coronary heart disease risk. Circulation 82(2), 495-506 (1990).
    • (1990) Circulation , vol.82 , Issue.2 , pp. 495-506
    • Austin, M.A.1    King, M.C.2    Vranizan, W.3    Krauss, R.M.4
  • 5
    • 0026526186 scopus 로고
    • Low density lipoprotein particle size and coronary artery disease
    • Campos H, Genest JJ Jr, Blijlevens E et al.: Low density lipoprotein particle size and coronary artery disease. Arterioscler. Thromb. 12(2), 187-195 (1992).
    • (1992) Arterioscler. Thromb , vol.12 , Issue.2 , pp. 187-195
    • Campos, H.1    Genest Jr, J.J.2    Blijlevens, E.3
  • 6
    • 0035292693 scopus 로고    scopus 로고
    • Lipoprotein subclasses and atherosclerosis
    • Superko RH: Lipoprotein subclasses and atherosclerosis. Front. Biosci. 6, D355-D365 (2001).
    • (2001) Front. Biosci , vol.6
    • Superko, R.H.1
  • 7
    • 34447520136 scopus 로고    scopus 로고
    • Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women
    • Bansal S, Buring JE, Rifai N, Mora S, Sacks FM, Ridker PM: Fasting compared with nonfasting triglycerides and risk of cardiovascular events in women. JAMA 298(3), 309-316 (2007).
    • (2007) JAMA , vol.298 , Issue.3 , pp. 309-316
    • Bansal, S.1    Buring, J.E.2    Rifai, N.3    Mora, S.4    Sacks, F.M.5    Ridker, P.M.6
  • 8
    • 34447511196 scopus 로고    scopus 로고
    • Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women
    • Nordestgaard BG, Benn M, Schnohr P, Tybjaerg-Hansen A: Nonfasting triglycerides and risk of myocardial infarction, ischemic heart disease, and death in men and women. JAMA 298(3), 299-308(2007).
    • (2007) JAMA , vol.298 , Issue.3 , pp. 299-308
    • Nordestgaard, B.G.1    Benn, M.2    Schnohr, P.3    Tybjaerg-Hansen, A.4
  • 9
    • 33846637379 scopus 로고    scopus 로고
    • Triglycerides and the risk of coronary heart disease: 10, 158 incident cases among 262,525 participants in 29 Western prospective studies
    • Sarwar N, Danesh J, Eiriksdottir G et al.: Triglycerides and the risk of coronary heart disease: 10, 158 incident cases among 262,525 participants in 29 Western prospective studies. Circulation 115 (4), 450-458 (2007).
    • (2007) Circulation , vol.115 , Issue.4 , pp. 450-458
    • Sarwar, N.1    Danesh, J.2    Eiriksdottir, G.3
  • 10
    • 38749102352 scopus 로고    scopus 로고
    • Fasting versus nonfasting triglycerides and the prediction of cardiovascular risk: Do we need to revisit the oral triglyceride tolerance test?
    • Ridker PM: Fasting versus nonfasting triglycerides and the prediction of cardiovascular risk: do we need to revisit the oral triglyceride tolerance test? Clin. Chem. 54(1), 11-13 (2008).
    • (2008) Clin. Chem , vol.54 , Issue.1 , pp. 11-13
    • Ridker, P.M.1
  • 11
    • 38749087599 scopus 로고    scopus 로고
    • Fasting versus nonfasting triglycerides: Implications for laboratory measurements
    • Warnick GR, Nakajima K. Fasting versus nonfasting triglycerides: implications for laboratory measurements. Clin. Chem. 54(1), 14-16 (2008).
    • (2008) Clin. Chem , vol.54 , Issue.1 , pp. 14-16
    • Warnick, G.R.1    Nakajima, K.2
  • 12
    • 1042268030 scopus 로고    scopus 로고
    • Hepatic catabolism of remnant lipoproteins: Where the action is
    • Havel RJ, Hamilton RL. Hepatic catabolism of remnant lipoproteins: where the action is. Arterioscler. Thromb. Vasc. Biol. 24(2), 213-215 (2004).
    • (2004) Arterioscler. Thromb. Vasc. Biol , vol.24 , Issue.2 , pp. 213-215
    • Havel, R.J.1    Hamilton, R.L.2
  • 14
    • 33947138220 scopus 로고    scopus 로고
    • Effects of lipoprotein lipase and statins on cholesterol uptake into heart and skeletal muscle
    • Yokoyama M, Seo, T, Park T et al.: Effects of lipoprotein lipase and statins on cholesterol uptake into heart and skeletal muscle. J. Lipid Res. 48(3), 646-655 (2007).
    • (2007) J. Lipid Res , vol.48 , Issue.3 , pp. 646-655
    • Yokoyama, M.1    Seo, T.2    Park, T.3
  • 16
    • 0346880515 scopus 로고    scopus 로고
    • Alterations in high-density lipoprotein metabolism and reverse cholesterol transport in insulin resistance and Type 2 diabetes mellitus: Role of lipolytic enzymes, lecithin:cholesterol acyltransferase and lipid transfer protein
    • Borggreve SE, de Vries R, Dullaart RP: Alterations in high-density lipoprotein metabolism and reverse cholesterol transport in insulin resistance and Type 2 diabetes mellitus: role of lipolytic enzymes, lecithin:cholesterol acyltransferase and lipid transfer protein. Eur. J. Clin. Invrst. 33(12), 1051-1069 (2003).
    • (2003) Eur. J. Clin. Invrst , vol.33 , Issue.12 , pp. 1051-1069
    • Borggreve, S.E.1    de Vries, R.2    Dullaart, R.P.3
  • 17
    • 34248380100 scopus 로고    scopus 로고
    • Concerted actions of cholesteryl ester transfer protein and phospholipid transfer protein in Type 2 diabetes: Effects of apolipoproteins
    • Dallinga-Thie G M, Dullaart RP, van Tot A: Concerted actions of cholesteryl ester transfer protein and phospholipid transfer protein in Type 2 diabetes: effects of apolipoproteins. Curr. Opin. Lipidol. 18(3), 251 257 (2007).
    • (2007) Curr. Opin. Lipidol , vol.18 , Issue.3 , pp. 251-257
    • Dallinga-Thie, G.M.1    Dullaart, R.P.2    van Tot, A.3
  • 18
    • 0036906508 scopus 로고    scopus 로고
    • Lipoprotein lipase: Genetics, lipid uptake, and regulation
    • Merkel M, Eckel RH, Goldberg IJ: Lipoprotein lipase: genetics, lipid uptake, and regulation. J. Lipid Res. 43(12), 1997-2006 (2002).
    • (2002) J. Lipid Res , vol.43 , Issue.12 , pp. 1997-2006
    • Merkel, M.1    Eckel, R.H.2    Goldberg, I.J.3
  • 19
    • 33846007667 scopus 로고    scopus 로고
    • Atherogenic remnant lipoproteins: Role for proteoglycans in trapping, transferring, and internalizing
    • Mahley RW, Huang Y: Atherogenic remnant lipoproteins: role for proteoglycans in trapping, transferring, and internalizing. J. Clin. Invest. 117(l), 94-98 (2007).
    • (2007) J. Clin. Invest , vol.117 , Issue.L , pp. 94-98
    • Mahley, R.W.1    Huang, Y.2
  • 20
    • 33846012847 scopus 로고    scopus 로고
    • Liver heparan sulfate proteoglycans mediate clearance of triglyceride-rich lipoproteins independently of LDL receptor family members
    • MacArthur JM, Bishop JR, Stanford IG et al.: Liver heparan sulfate proteoglycans mediate clearance of triglyceride-rich lipoproteins independently of LDL receptor family members. J. Clin. Invest. 117(1), 153-164 (2007).
    • (2007) J. Clin. Invest , vol.117 , Issue.1 , pp. 153-164
    • MacArthur, J.M.1    Bishop, J.R.2    Stanford, I.G.3
  • 21
    • 34247610845 scopus 로고    scopus 로고
    • Heparan sulphate proteoglycans fine-tune mammalian physiology
    • Bishop JR, Schuksz M, Esko JD: Heparan sulphate proteoglycans fine-tune mammalian physiology. Nature 446(7139), 1030-1037(2007).
    • (2007) Nature , vol.446 , Issue.7139 , pp. 1030-1037
    • Bishop, J.R.1    Schuksz, M.2    Esko, J.D.3
  • 22
    • 0003024548 scopus 로고
    • Abolishment of alimentary lipemia following injection of heparin
    • Hahn PF: Abolishment of alimentary lipemia following injection of heparin. Science 98(2531), 19-20 (1943).
    • (1943) Science , vol.98 , Issue.2531 , pp. 19-20
    • Hahn, P.F.1
  • 23
    • 0005026320 scopus 로고
    • Clearing factor, a heparin-activated lipoprorcin lipase. II. Substrate specificity and activation of coconut oil
    • Korn ED: Clearing factor, a heparin-activated lipoprorcin lipase. II. Substrate specificity and activation of coconut oil. J. Biol Chem. 215(1), 15-26 (1955).
    • (1955) J. Biol Chem , vol.215 , Issue.1 , pp. 15-26
    • Korn, E.D.1
  • 25
    • 0028819754 scopus 로고
    • Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes
    • Weinstock PH, Bisgaier CL, Aalto-Setala K et al.: Severe hypertriglyceridemia, reduced high density lipoprotein, and neonatal death in lipoprotein lipase knockout mice. Mild hypertriglyceridemia with impaired very low density lipoprotein clearance in heterozygotes. J. Clin. Invest. 96(6), 2555-2568 (1995).
    • (1995) J. Clin. Invest , vol.96 , Issue.6 , pp. 2555-2568
    • Weinstock, P.H.1    Bisgaier, C.L.2    Aalto-Setala, K.3
  • 26
    • 0025908609 scopus 로고
    • Lipoprotein lipase
    • Bensadoun A: Lipoprotein lipase. Annu. Rev. Nutr. 11, 217-23 7 (1991).
    • (1991) Annu. Rev. Nutr , vol.11 , Issue.217-223 , pp. 7
    • Bensadoun, A.1
  • 27
    • 24744459686 scopus 로고    scopus 로고
    • Differential regulation and properties of angiopoietin-like proteins 3 and 4
    • Ge H, Cha JY, Gopal H et al.: Differential regulation and properties of angiopoietin-like proteins 3 and 4. J. Lipid Res. 46(7), 1484-1490 (2005).
    • (2005) J. Lipid Res , vol.46 , Issue.7 , pp. 1484-1490
    • Ge, H.1    Cha, J.Y.2    Gopal, H.3
  • 28
    • 36549038120 scopus 로고    scopus 로고
    • Mutations in LMF1 Cause combined lipase deficiency and severe hypertriglyceridemia
    • Peterfy M, Ben-Zeev O, Mao HZ et al.: Mutations in LMF1 Cause combined lipase deficiency and severe hypertriglyceridemia. Nat. Genet. 39(12), 1483-1487 (2007).
    • (2007) Nat. Genet , vol.39 , Issue.12 , pp. 1483-1487
    • Peterfy, M.1    Ben-Zeev, O.2    Mao, H.Z.3
  • 29
    • 0029971197 scopus 로고    scopus 로고
    • Naturally occurring mutations in mice affecting lipid transport and metabolism
    • Reue K, Doolittle MH: Naturally occurring mutations in mice affecting lipid transport and metabolism. J. Lipid Res. 37(7), 1387-1405 (1996).
    • (1996) J. Lipid Res , vol.37 , Issue.7 , pp. 1387-1405
    • Reue, K.1    Doolittle, M.H.2
  • 30
    • 0025115935 scopus 로고
    • Combined lipase deficiency in the mouse. Evidence of impaired lipase processing and secretion
    • Davis RC, Ben-Zeev O, Martin D, Doolittle MH: Combined lipase deficiency in the mouse. Evidence of impaired lipase processing and secretion. J. Mol. Chem. 265(29), 17960-17966 (1990).
    • (1990) J. Mol. Chem , vol.265 , Issue.29 , pp. 17960-17966
    • Davis, R.C.1    Ben-Zeev, O.2    Martin, D.3    Doolittle, M.H.4
  • 31
    • 0030886302 scopus 로고    scopus 로고
    • Lipid binding of apolipoprotein CII is required for stimulation of lipoprotein lipase activity against apolipoprotein CII-deficient chylomicrons
    • Olivecrona G, Beisiegel U: Lipid binding of apolipoprotein CII is required for stimulation of lipoprotein lipase activity against apolipoprotein CII-deficient chylomicrons. Arterioscler. Thromb. Vasc. Biol. 17(8), 1545-1549 (1997).
    • (1997) Arterioscler. Thromb. Vasc. Biol , vol.17 , Issue.8 , pp. 1545-1549
    • Olivecrona, G.1    Beisiegel, U.2
  • 32
    • 9644302478 scopus 로고    scopus 로고
    • Rapid subunit exchange in dimeric lipoprotein lipase and properties of the inactive monomer
    • Lookene A, Zhang L, Hultin M, Olivecrona G: Rapid subunit exchange in dimeric lipoprotein lipase and properties of the inactive monomer. J. Biol. Chem. 279(48), 49964-49972 (2004).
    • (2004) J. Biol. Chem , vol.279 , Issue.48 , pp. 49964-49972
    • Lookene, A.1    Zhang, L.2    Hultin, M.3    Olivecrona, G.4
  • 33
    • 0034983440 scopus 로고    scopus 로고
    • Apolipoproteips C-I and C-III as important modulators of lipoprotein metabolism
    • Shachter NS: Apolipoproteips C-I and C-III as important modulators of lipoprotein metabolism. Curr. Opin. Lipidol. 12(3), 297-304 (2001).
    • (2001) Curr. Opin. Lipidol , vol.12 , Issue.3 , pp. 297-304
    • Shachter, N.S.1
  • 34
    • 3142581525 scopus 로고    scopus 로고
    • ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis
    • Schaap FG, Rensen PC, Voshol PJ et al.: ApoAV reduces plasma triglycerides by inhibiting very low density lipoprotein-triglyceride (VLDL-TG) production and stimulating lipoprotein lipase-mediated VLDL-TG hydrolysis. J. Biol. Chem. 279(27), 27941-27947 (2004).
    • (2004) J. Biol. Chem , vol.279 , Issue.27 , pp. 27941-27947
    • Schaap, F.G.1    Rensen, P.C.2    Voshol, P.J.3
  • 35
    • 33751213896 scopus 로고    scopus 로고
    • Angiopoietin-like protein 4 converts lipoprotein lipase to inactive monomers and modulates lipase activity in adipose tissue
    • Sukonina V, Lookene A, Olivecrona T, Olivecrona G: Angiopoietin-like protein 4 converts lipoprotein lipase to inactive monomers and modulates lipase activity in adipose tissue. Proc. Natl Acad. Sci. USA 103(46), 17450-17455 (2006).
    • (2006) Proc. Natl Acad. Sci. USA , vol.103 , Issue.46 , pp. 17450-17455
    • Sukonina, V.1    Lookene, A.2    Olivecrona, T.3    Olivecrona, G.4
  • 37
    • 34547653030 scopus 로고    scopus 로고
    • The increase of apolipoprotein A-V during postprandial lipemia parallels the response of triglyceride-rich lipoproteins in Type 2 diabetes: No relationship between apoA-V and postheparin plasma lipolytic activity
    • Kahri J, Fruchart-Najib J, Matikainen N, Fruchart JC, Vakkilainen J, Taskinen MR: The increase of apolipoprotein A-V during postprandial lipemia parallels the response of triglyceride-rich lipoproteins in Type 2 diabetes: no relationship between apoA-V and postheparin plasma lipolytic activity. Diabetes Care 30(8), 2083-2085 (2007).
    • (2007) Diabetes Care , vol.30 , Issue.8 , pp. 2083-2085
    • Kahri, J.1    Fruchart-Najib, J.2    Matikainen, N.3    Fruchart, J.C.4    Vakkilainen, J.5    Taskinen, M.R.6
  • 38
    • 0026748770 scopus 로고
    • Inhibition of lipoprotein lipase activity by synthetic peptides of apolipoprotein C-III
    • McConathy WJ, Gesquiere JC, Bass H, Tartar A, Frucharr JC, Wang CS: Inhibition of lipoprotein lipase activity by synthetic peptides of apolipoprotein C-III. J. Lipid Res. 33(7), 995-1003 (1992).
    • (1992) J. Lipid Res , vol.33 , Issue.7 , pp. 995-1003
    • McConathy, W.J.1    Gesquiere, J.C.2    Bass, H.3    Tartar, A.4    Frucharr, J.C.5    Wang, C.S.6
  • 39
    • 20144375048 scopus 로고    scopus 로고
    • Apolipoprotein AV accelerates plasma hydrolysis of triglyceride-rich lipoproteins by interaction with proteoglycan-bound lipoprotein lipase
    • Merkel M, Loeffler B, Kluger M et al.: Apolipoprotein AV accelerates plasma hydrolysis of triglyceride-rich lipoproteins by interaction with proteoglycan-bound lipoprotein lipase. J. Biol. Chem. 280(22), 21553-21560 (2005).
    • (2005) J. Biol. Chem , vol.280 , Issue.22 , pp. 21553-21560
    • Merkel, M.1    Loeffler, B.2    Kluger, M.3
  • 40
    • 34447314745 scopus 로고    scopus 로고
    • GPIHBPl: An endothelial cell molecule important for the lipolytic processing of chylomicrons
    • Young SG, Davies BS, Fong LG et al.: GPIHBPl: an endothelial cell molecule important for the lipolytic processing of chylomicrons. Curr. Opin. Lipidol. 18(4), 389-396 (2007).
    • (2007) Curr. Opin. Lipidol , vol.18 , Issue.4 , pp. 389-396
    • Young, S.G.1    Davies, B.S.2    Fong, L.G.3
  • 41
    • 33947573537 scopus 로고    scopus 로고
    • Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons
    • Beigneux AP, Davies BS, Gin P et al.: Glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 plays a critical role in the lipolytic processing of chylomicrons. Cell Metab. 5(4), 279-291 (2007).
    • (2007) Cell Metab , vol.5 , Issue.4 , pp. 279-291
    • Beigneux, A.P.1    Davies, B.S.2    Gin, P.3
  • 42
    • 36048975597 scopus 로고    scopus 로고
    • Resequencing genomic DNA of patients with severe hypertriglyceridemia (MIM 144650)
    • Wang J, Cao H, Ban MR et al.: Resequencing genomic DNA of patients with severe hypertriglyceridemia (MIM 144650). Arterioscler. Thromb. Vasc. Biol. 27(11), 2450-2455 (2007).
    • (2007) Arterioscler. Thromb. Vasc. Biol , vol.27 , Issue.11 , pp. 2450-2455
    • Wang, J.1    Cao, H.2    Ban, M.R.3
  • 43
    • 0030056398 scopus 로고    scopus 로고
    • Molecular pathobiology of the human lipoprotein lipase gene
    • Murthy V, Julien P, Gagne C: Molecular pathobiology of the human lipoprotein lipase gene. Pharmacol. Ther. 70(2), 101-135 (1996).
    • (1996) Pharmacol. Ther , vol.70 , Issue.2 , pp. 101-135
    • Murthy, V.1    Julien, P.2    Gagne, C.3
  • 44
    • 0032822705 scopus 로고    scopus 로고
    • Delayed clearance of postprandial large TG-rich particles in normolipidemic carriers of LPL Asn291Ser gene variant
    • Mero N, Suurinkeroinen L, Syvanne M, Knudsen P, Yki-Jarvinen H, Taskinen MR: Delayed clearance of postprandial large TG-rich particles in normolipidemic carriers of LPL Asn291Ser gene variant. J. Lipid Res. 40(9), 1663-1670 (1999).
    • (1999) J. Lipid Res , vol.40 , Issue.9 , pp. 1663-1670
    • Mero, N.1    Suurinkeroinen, L.2    Syvanne, M.3    Knudsen, P.4    Yki-Jarvinen, H.5    Taskinen, M.R.6
  • 45
    • 0033536024 scopus 로고    scopus 로고
    • Lipoprotein lipase mutations, plasma lipids and lipoproteins, and risk of ischemic heart disease. A meta-analysis
    • Wittrup HH, Tybjaerg-Hansen A, Nordestgaard BG: Lipoprotein lipase mutations, plasma lipids and lipoproteins, and risk of ischemic heart disease. A meta-analysis. Circulation 99(22), 2901-2907 (1999).
    • (1999) Circulation , vol.99 , Issue.22 , pp. 2901-2907
    • Wittrup, H.H.1    Tybjaerg-Hansen, A.2    Nordestgaard, B.G.3
  • 46
    • 0032722471 scopus 로고    scopus 로고
    • Two common mutations (D9N, N291S) in lipoprotein lipase: A cumulative analysis of their influence on plasma lipids and lipoproteins in men and women
    • Kastelein JJ, Ordovas JM, Wittekoek ME et al.: Two common mutations (D9N, N291S) in lipoprotein lipase: a cumulative analysis of their influence on plasma lipids and lipoproteins in men and women. Clin. Genet. 56(4), 297-305 (1999).
    • (1999) Clin. Genet , vol.56 , Issue.4 , pp. 297-305
    • Kastelein, J.J.1    Ordovas, J.M.2    Wittekoek, M.E.3
  • 47
    • 0030745465 scopus 로고    scopus 로고
    • Lipoprotein lipase gene variants and risk of coronary disease: A quantitative analysis of population-based studies
    • Hokanson JE: Lipoprotein lipase gene variants and risk of coronary disease: a quantitative analysis of population-based studies. Int. J. Clin. Lab. Res. 27(1), 24-34 (1997).
    • (1997) Int. J. Clin. Lab. Res , vol.27 , Issue.1 , pp. 24-34
    • Hokanson, J.E.1
  • 48
    • 0034966105 scopus 로고    scopus 로고
    • Lipoprotein lipase D9N, N291S and S447X polymorphisms: Their influence on premature coronary heart disease and plasma lipids
    • Van Bockxmeer FM, Lin Q, Mamotte C, Burke V, Taylor R: Lipoprotein lipase D9N, N291S and S447X polymorphisms: their influence on premature coronary heart disease and plasma lipids. Atherosclerosis 157(1), 123-129 (2001).
    • (2001) Atherosclerosis , vol.157 , Issue.1 , pp. 123-129
    • Van Bockxmeer, F.M.1    Lin, Q.2    Mamotte, C.3    Burke, V.4    Taylor, R.5
  • 49
    • 0032478291 scopus 로고    scopus 로고
    • A common mutation in the lipoprotein lipase gene (N291S) alters the lipoprotein phenotype and risk for cardiovascular disease in patients with familial hypercholesterolemia
    • Wittekoek ME, Pimstone SN, Reymer PW et al.: A common mutation in the lipoprotein lipase gene (N291S) alters the lipoprotein phenotype and risk for cardiovascular disease in patients with familial hypercholesterolemia. Circulation 97(8), 729-735 (1998).
    • (1998) Circulation , vol.97 , Issue.8 , pp. 729-735
    • Wittekoek, M.E.1    Pimstone, S.N.2    Reymer, P.W.3
  • 50
    • 0032718547 scopus 로고    scopus 로고
    • A frequent mutation in the lipoprotein lipase gene (D9N) deteriorates the biochemical and clinical phenotype of familial hypercholesterolemia
    • Wittekock ME, Moll E, Pimstone SN et al.: A frequent mutation in the lipoprotein lipase gene (D9N) deteriorates the biochemical and clinical phenotype of familial hypercholesterolemia. Arterioscler. Thromb. Vasc. Biol. 19(11), 2708-2713 (1999).
    • (1999) Arterioscler. Thromb. Vasc. Biol , vol.19 , Issue.11 , pp. 2708-2713
    • Wittekock, M.E.1    Moll, E.2    Pimstone, S.N.3
  • 51
    • 0033396880 scopus 로고    scopus 로고
    • Functional variants in the lipoprotein lipase gene and risk cardiovascular disease
    • Hokanson JE: Functional variants in the lipoprotein lipase gene and risk cardiovascular disease. Curr. Opin. Lipidol. 10(5), 393-399 (1999).
    • (1999) Curr. Opin. Lipidol , vol.10 , Issue.5 , pp. 393-399
    • Hokanson, J.E.1
  • 52
    • 0031905812 scopus 로고    scopus 로고
    • The Asn9 variant of lipoprotein lipase is associated with the 93G promoter mutation and an increased risk of coronary artery disease. The Regress Study Group
    • Kastelein JJ, Groenemeyer BE, Hallman DM et al.: The Asn9 variant of lipoprotein lipase is associated with the 93G promoter mutation and an increased risk of coronary artery disease. The Regress Study Group. Clin. Genet. 53(1), 27-33 (1998).
    • (1998) Clin. Genet , vol.53 , Issue.1 , pp. 27-33
    • Kastelein, J.J.1    Groenemeyer, B.E.2    Hallman, D.M.3
  • 54
    • 0032792469 scopus 로고    scopus 로고
    • A common truncation variant of lipoprotein lipase (Ser447X) confers protection against coronary heart disease: The Framingham Offspring Study
    • Gagne SE, Larson MG, Pimstone SN et al.: A common truncation variant of lipoprotein lipase (Ser447X) confers protection against coronary heart disease: the Framingham Offspring Study. Clin. Genet. 55(6), 450-454 (1999).
    • (1999) Clin. Genet , vol.55 , Issue.6 , pp. 450-454
    • Gagne, S.E.1    Larson, M.G.2    Pimstone, S.N.3
  • 55
    • 0032914885 scopus 로고    scopus 로고
    • Lipoprotein lipase activity is decreased in a large cohort of patients with coronary artery disease and is associated with changes in lipids and lipoproteins
    • Henderson HE, Kastelein JJ, Zwinderman AH et al.: Lipoprotein lipase activity is decreased in a large cohort of patients with coronary artery disease and is associated with changes in lipids and lipoproteins. J. Lipid Res. 40(4), 735-743 (1999).
    • (1999) J. Lipid Res , vol.40 , Issue.4 , pp. 735-743
    • Henderson, H.E.1    Kastelein, J.J.2    Zwinderman, A.H.3
  • 56
    • 0028883699 scopus 로고
    • Lipoprotein lipase gene polymorphisms: Associations with myocardial infarction and lipoprotein levels, the ECTIM study. Etude Cas Temoin sur l'Infarctus du Myocarde
    • Jemaa R, Fumeron F, Poirier O et al.: Lipoprotein lipase gene polymorphisms: associations with myocardial infarction and lipoprotein levels, the ECTIM study. Etude Cas Temoin sur l'Infarctus du Myocarde. J. Lipid Res. 36(10), 2141-2146 (1995).
    • (1995) J. Lipid Res , vol.36 , Issue.10 , pp. 2141-2146
    • Jemaa, R.1    Fumeron, F.2    Poirier, O.3
  • 57
    • 0034791305 scopus 로고    scopus 로고
    • Association of lipoprotein lipase Ser447Ter polymorphism with brain infarction: A population-based neuropathological study
    • Myllykangas L, Polvikoski T, Sulkava R et al.: Association of lipoprotein lipase Ser447Ter polymorphism with brain infarction: a population-based neuropathological study. Ann. Med. 33(7), 486-492 (2001).
    • (2001) Ann. Med , vol.33 , Issue.7 , pp. 486-492
    • Myllykangas, L.1    Polvikoski, T.2    Sulkava, R.3
  • 58
    • 0034946410 scopus 로고    scopus 로고
    • Polymorphism of the lipoprotein lipase gene and risk of atherothrombotic cerebral infarction in the Japanese
    • Shimo-Nakanishi Y, Urabe T, Hattori N et al.: Polymorphism of the lipoprotein lipase gene and risk of atherothrombotic cerebral infarction in the Japanese. Stroke 32(7), 1481-1486 (2001).
    • (2001) Stroke , vol.32 , Issue.7 , pp. 1481-1486
    • Shimo-Nakanishi, Y.1    Urabe, T.2    Hattori, N.3
  • 59
    • 0027455653 scopus 로고
    • Dietary treatment and growth of hyperchylomicronemic children severely restricted in dietary fat
    • Black DM, Sprecher DL: Dietary treatment and growth of hyperchylomicronemic children severely restricted in dietary fat. Am. J. Dis. Child 147(1), 60-62 (1993).
    • (1993) Am. J. Dis. Child , vol.147 , Issue.1 , pp. 60-62
    • Black, D.M.1    Sprecher, D.L.2
  • 61
    • 0024533690 scopus 로고
    • Primary lipoprotein-lipase-activity deficiency: Clinical investigation of a French Canadian population
    • Gagne C, Brun LD, Julien P, Moorjani S, Lupien PJ: Primary lipoprotein-lipase-activity deficiency: clinical investigation of a French Canadian population. CMAJ 140(4), 405-411 (1989).
    • (1989) CMAJ , vol.140 , Issue.4 , pp. 405-411
    • Gagne, C.1    Brun, L.D.2    Julien, P.3    Moorjani, S.4    Lupien, P.J.5
  • 62
    • 0025604596 scopus 로고
    • Hyperlipidemic pancreatitis
    • Toskes PP: Hyperlipidemic pancreatitis. Gastroenterol. Clin. North Am. 19(4), 783-791 (1990).
    • (1990) Gastroenterol. Clin. North Am , vol.19 , Issue.4 , pp. 783-791
    • Toskes, P.P.1
  • 63
    • 41149172390 scopus 로고    scopus 로고
    • Spontaneous atherosclerosis in aged lipoprotein lipase-deficient mice with severe hypertriglyceridemia on a normal chow diet
    • Zhang X, Qi R, Xian X et al.: Spontaneous atherosclerosis in aged lipoprotein lipase-deficient mice with severe hypertriglyceridemia on a normal chow diet. Circ. Res. 102(2), 250-256 (2008).
    • (2008) Circ. Res , vol.102 , Issue.2 , pp. 250-256
    • Zhang, X.1    Qi, R.2    Xian, X.3
  • 64
    • 0029808302 scopus 로고    scopus 로고
    • Premature atherosclerosis in patients with familial chylomicronemia caused by mutations in the lipoprotein lipase gene
    • Benlian P, De Gennes JL, Foubert L, Zhang H, Gagne SE, Hayden M: Premature atherosclerosis in patients with familial chylomicronemia caused by mutations in the lipoprotein lipase gene. N. Engl. J. Med. 335(12), 848-854 (1996).
    • (1996) N. Engl. J. Med , vol.335 , Issue.12 , pp. 848-854
    • Benlian, P.1    De Gennes, J.L.2    Foubert, L.3    Zhang, H.4    Gagne, S.E.5    Hayden, M.6
  • 65
    • 12444316058 scopus 로고    scopus 로고
    • Novel LPL mutation (L303F) found in a patient associated with coronary artery disease and severe systemic atherosclerosis
    • Saika Y, Sakai N, Takahashi M et al.: Novel LPL mutation (L303F) found in a patient associated with coronary artery disease and severe systemic atherosclerosis. Eur. J. Clin. Invest. 33(3), 216-222 (2003).
    • (2003) Eur. J. Clin. Invest , vol.33 , Issue.3 , pp. 216-222
    • Saika, Y.1    Sakai, N.2    Takahashi, M.3
  • 66
    • 0030911585 scopus 로고    scopus 로고
    • Chylomicronemia due to apolipoprotein CIII overexpression in apolipoprotein E-null mice. Apolipoprotein CIII-induced hypertriglyceridemia is not mediated by effects on apolipoprotein E
    • Ebara T, Ramakrishnan R, Steiner G, Shachter NS: Chylomicronemia due to apolipoprotein CIII overexpression in apolipoprotein E-null mice. Apolipoprotein CIII-induced hypertriglyceridemia is not mediated by effects on apolipoprotein E. J. Clin. Invest. 99(11), 2672-2681 (1997).
    • (1997) J. Clin. Invest , vol.99 , Issue.11 , pp. 2672-2681
    • Ebara, T.1    Ramakrishnan, R.2    Steiner, G.3    Shachter, N.S.4
  • 67
    • 35448983964 scopus 로고    scopus 로고
    • Homozygous missense mutation (G56R) in glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 (GPI-HBP1) in two siblings with fasting chylomicronemia (MIM 144650)
    • Wang J, Hegele RA: Homozygous missense mutation (G56R) in glycosylphosphatidylinositol-anchored high-density lipoprotein-binding protein 1 (GPI-HBP1) in two siblings with fasting chylomicronemia (MIM 144650). Lipids Health Dis. 6, 23 (2007).
    • (2007) Lipids Health Dis , vol.6 , pp. 23
    • Wang, J.1    Hegele, R.A.2
  • 68
    • 38649132270 scopus 로고    scopus 로고
    • Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans
    • Kathiresan S, Melander O, Guiducci C et al.: Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. Nat. Genet. 40(2), 189-197 (2008).
    • (2008) Nat. Genet , vol.40 , Issue.2 , pp. 189-197
    • Kathiresan, S.1    Melander, O.2    Guiducci, C.3
  • 69
    • 34247471569 scopus 로고    scopus 로고
    • Hypertriglyceridemia: Its etiology, effects and treatment
    • Yuan G, Al-Shali KZ, Hegele RA: Hypertriglyceridemia: its etiology, effects and treatment. CMAJ 176(8), 1113-1120 (2007).
    • (2007) CMAJ , vol.176 , Issue.8 , pp. 1113-1120
    • Yuan, G.1    Al-Shali, K.Z.2    Hegele, R.A.3
  • 70
    • 34548433987 scopus 로고    scopus 로고
    • Clinical practice. Hypertriglyceridemia
    • Brunzell JD: Clinical practice. Hypertriglyceridemia. N. Engl. J. Med. 357(10), 1009-1017 (2007).
    • (2007) N. Engl. J. Med , vol.357 , Issue.10 , pp. 1009-1017
    • Brunzell, J.D.1
  • 72
    • 0042329251 scopus 로고    scopus 로고
    • Dyslipidaemia
    • Durrington P: Dyslipidaemia. Lancet 362(9385), 717-731 (2003).
    • (2003) Lancet , vol.362 , Issue.9385 , pp. 717-731
    • Durrington, P.1
  • 73
    • 0019474574 scopus 로고
    • Influence of nicotinic acid on metabolism of cholesterol and triglycerides in man
    • Grundy SM, Mok HY, Zech L, Berman M: Influence of nicotinic acid on metabolism of cholesterol and triglycerides in man. J. Lipid Res. 22(1), 24-36 (1981).
    • (1981) J. Lipid Res , vol.22 , Issue.1 , pp. 24-36
    • Grundy, S.M.1    Mok, H.Y.2    Zech, L.3    Berman, M.4
  • 74
    • 0032951101 scopus 로고    scopus 로고
    • Niacin accelerates intracellular ApoB degradation by inhibiting triacylglycerol synthesis in human hepatoblastoma (HepG2) cells
    • Jin FY, Kamanna VS, Kashyap ML: Niacin accelerates intracellular ApoB degradation by inhibiting triacylglycerol synthesis in human hepatoblastoma (HepG2) cells. Arterioscler. Thromb. Vasc. Biol. 19(4), 1051-1059 (1999):
    • (1999) Arterioscler. Thromb. Vasc. Biol , vol.19 , Issue.4 , pp. 1051-1059
    • Jin, F.Y.1    Kamanna, V.S.2    Kashyap, M.L.3
  • 75
    • 41949100903 scopus 로고    scopus 로고
    • Effects of laropiprant on nicotinic acid-induced flushing in patients with dyslipidemia
    • Paolini JE, Mitchel YB, Reyes R et al.: Effects of laropiprant on nicotinic acid-induced flushing in patients with dyslipidemia. Am. J. Cardiol. 101(5), 625-630 (2008).
    • (2008) Am. J. Cardiol , vol.101 , Issue.5 , pp. 625-630
    • Paolini, J.E.1    Mitchel, Y.B.2    Reyes, R.3
  • 76
    • 0032567905 scopus 로고    scopus 로고
    • Vega GL, Grundy SM: Effect of starins on metabolism of apo-B-containing lipoproteins in hypertriglyceridemic men. Am. J. Cardiol. 81(4A), 36B-42B (1998).
    • Vega GL, Grundy SM: Effect of starins on metabolism of apo-B-containing lipoproteins in hypertriglyceridemic men. Am. J. Cardiol. 81(4A), 36B-42B (1998).
  • 77
    • 33748303084 scopus 로고    scopus 로고
    • Reduction of low-density lipoprotein cholesterol in patients with coronary heart disease and metabolic syndrome: Analysis of die Treating to New Targets study
    • Deedwania P, Barter P, Carmena. R et al.: Reduction of low-density lipoprotein cholesterol in patients with coronary heart disease and metabolic syndrome: analysis of die Treating to New Targets study. Lancet 368(9539), 919-928 (2006).
    • (2006) Lancet , vol.368 , Issue.9539 , pp. 919-928
    • Deedwania, P.1    Barter, P.2    Carmena, R.3
  • 78
    • 0035431019 scopus 로고    scopus 로고
    • The effect of aggressive versus standard lipid lowering by atorvastatin on diabetic dyslipidemia: The DALI study: a double-blind, randomized, placebo-controlled trial in patients with type 2 diabetes and diabetic dyslipidemia
    • Diabetes Atorvastin Lipid Intervention (DALI) Study Group
    • Diabetes Atorvastin Lipid Intervention (DALI) Study Group: The effect of aggressive versus standard lipid lowering by atorvastatin on diabetic dyslipidemia: the DALI study: a double-blind, randomized, placebo-controlled trial in patients with type 2 diabetes and diabetic dyslipidemia. Diabetes Care 24(8), 1335-1341 (2001).
    • (2001) Diabetes Care , vol.24 , Issue.8 , pp. 1335-1341
  • 79
    • 19244365650 scopus 로고    scopus 로고
    • Thiazolidinediones
    • Yki-Jarvinen H: Thiazolidinediones. N. Engl. J. Med. 351(11), 1106-1118 (2004).
    • (2004) N. Engl. J. Med , vol.351 , Issue.11 , pp. 1106-1118
    • Yki-Jarvinen, H.1
  • 80
    • 33846929465 scopus 로고    scopus 로고
    • Rosenson RS: Effects of peroxisome proliferaror-activated receptors on lipoprotein metabolism and glucose control in Type 2 diabetes mellirus. Am. J. Cardiol. 99(4A), 96B-104B (2007).
    • Rosenson RS: Effects of peroxisome proliferaror-activated receptors on lipoprotein metabolism and glucose control in Type 2 diabetes mellirus. Am. J. Cardiol. 99(4A), 96B-104B (2007).
  • 81
    • 21544466158 scopus 로고    scopus 로고
    • A comparison of lipid and glycemic effects of pioglitazone and rosiglitazone in patients with Type 2 diabetes and dyslipidemia
    • Goldberg RB, Kendall DM, Deeg MA et al.: A comparison of lipid and glycemic effects of pioglitazone and rosiglitazone in patients with Type 2 diabetes and dyslipidemia. Diabetes Care 28(7), 1547-1554 (2005).
    • (2005) Diabetes Care , vol.28 , Issue.7 , pp. 1547-1554
    • Goldberg, R.B.1    Kendall, D.M.2    Deeg, M.A.3
  • 82
    • 41449110020 scopus 로고    scopus 로고
    • Prescription omega-3 fatty acids and their lipid effects: Physiologic mechanisms of action and clinical implications
    • Bays HE, Tighe AP, Sadovsky R, Davidson MH: Prescription omega-3 fatty acids and their lipid effects: physiologic mechanisms of action and clinical implications. Expert Rev. Cardiovasc. Ther. 6(3), 391-409 (2008).
    • (2008) Expert Rev. Cardiovasc. Ther , vol.6 , Issue.3 , pp. 391-409
    • Bays, H.E.1    Tighe, A.P.2    Sadovsky, R.3    Davidson, M.H.4
  • 84
    • 0031425356 scopus 로고    scopus 로고
    • Safety and efficacy of Omacor in severe hypertriglyceridemia
    • Harris WS, Ginsberg HN, Arunakul N et al.: Safety and efficacy of Omacor in severe hypertriglyceridemia. J. Cardiovarc. Risk 4(5-6), 385-391 (1997).
    • (1997) J. Cardiovarc. Risk , vol.4 , Issue.5-6 , pp. 385-391
    • Harris, W.S.1    Ginsberg, H.N.2    Arunakul, N.3
  • 85
    • 34247885908 scopus 로고    scopus 로고
    • Role of prescription omega-3 fatty acids in the treatment of hypertriglyceridemia
    • McKenney JM, Sica D: Role of prescription omega-3 fatty acids in the treatment of hypertriglyceridemia. Pharmacotherapy 27(5), 715-728 (2007).
    • (2007) Pharmacotherapy , vol.27 , Issue.5 , pp. 715-728
    • McKenney, J.M.1    Sica, D.2
  • 86
    • 0038281520 scopus 로고    scopus 로고
    • Ornega-3 fatty acid supplementation accelerates chylomicron triglyceride clearance
    • Park Y, Harris WS: Ornega-3 fatty acid supplementation accelerates chylomicron triglyceride clearance. J. Lipid Res. 44(3), 455-463 (2003).
    • (2003) J. Lipid Res , vol.44 , Issue.3 , pp. 455-463
    • Park, Y.1    Harris, W.S.2
  • 87
    • 0033789411 scopus 로고    scopus 로고
    • The effect of concentrated n-3 fatty acids versus gemfibrozil on plasma lipoproteins, low density lipoprotein heterogeneity and oxidizability in patients with hypertriglyceridemia
    • Stalenhoef AF, de Graaf J, Wittekoek ME, Bredie SJ, Demacker PN, Kastelein JJ: The effect of concentrated n-3 fatty acids versus gemfibrozil on plasma lipoproteins, low density lipoprotein heterogeneity and oxidizability in patients with hypertriglyceridemia. Atherosclerosis 153(1), 129-138 (2000).
    • (2000) Atherosclerosis , vol.153 , Issue.1 , pp. 129-138
    • Stalenhoef, A.F.1    de Graaf, J.2    Wittekoek, M.E.3    Bredie, S.J.4    Demacker, P.N.5    Kastelein, J.J.6
  • 88
    • 0032917836 scopus 로고    scopus 로고
    • Correlation of serum triglyceride and its reduction by omega-3 fatty acids with lipid transfer activity and the neutral lipid compositions of high-density and low-density lipoproteins
    • Pownall HJ, Branchi D, Kilinc C et al.: Correlation of serum triglyceride and its reduction by omega-3 fatty acids with lipid transfer activity and the neutral lipid compositions of high-density and low-density lipoproteins. Atherosclerosis 143(2), 285-297 (1999).
    • (1999) Atherosclerosis , vol.143 , Issue.2 , pp. 285-297
    • Pownall, H.J.1    Branchi, D.2    Kilinc, C.3
  • 89
    • 0013882158 scopus 로고
    • Absorption of medium and long chain triglycerides: Factors influencing their hydrolysis and transport
    • Greenberger NJ, Rodgers JB, Isselbacher KJ: Absorption of medium and long chain triglycerides: factors influencing their hydrolysis and transport. J. Clin. Invest. 45(2), 217-227 (1966).
    • (1966) J. Clin. Invest , vol.45 , Issue.2 , pp. 217-227
    • Greenberger, N.J.1    Rodgers, J.B.2    Isselbacher, K.J.3
  • 90
    • 0030804675 scopus 로고    scopus 로고
    • Therapeutic response to medium-chain triglycerides and ∞-3 fatty acids in a patient with the familial chylomicronemia syndrome
    • Rouis M, Dugi KA, Previato L et al.: Therapeutic response to medium-chain triglycerides and ∞-3 fatty acids in a patient with the familial chylomicronemia syndrome. Arierioscler. Thromb. Vasc. Biol. 17(7), 1400-1406 (1997).
    • (1997) Arierioscler. Thromb. Vasc. Biol , vol.17 , Issue.7 , pp. 1400-1406
    • Rouis, M.1    Dugi, K.A.2    Previato, L.3
  • 91
    • 0028905032 scopus 로고
    • Correction of hypertriglyceridemia with low high-density lipoprotein cholesterol by the novel compound NO-1886, a lipoprotein lipase-promoting agent, in STZ-induced diabetic rats
    • Tsutsumi K, Inoue Y, Shima A, Murase T: Correction of hypertriglyceridemia with low high-density lipoprotein cholesterol by the novel compound NO-1886, a lipoprotein lipase-promoting agent, in STZ-induced diabetic rats. Diabetes 44(4), 411-417 (1995).
    • (1995) Diabetes , vol.44 , Issue.4 , pp. 411-417
    • Tsutsumi, K.1    Inoue, Y.2    Shima, A.3    Murase, T.4
  • 92
    • 0027260912 scopus 로고
    • The novel compound NO-1886 increases lipoprotein lipase activity with resulting elevation of high density lipoprotein cholesterol, and long-term administration inhibits atherogenesis in the coronary arteries of rats with experimental atherosclerosis
    • Tsutsumi K, Inoue Y, Shima A, Iwasaki K, Kawamura M, Murase T. The novel compound NO-1886 increases lipoprotein lipase activity with resulting elevation of high density lipoprotein cholesterol, and long-term administration inhibits atherogenesis in the coronary arteries of rats with experimental atherosclerosis. J. Clin. Invest. 92(1), 411-417 (1993).
    • (1993) J. Clin. Invest , vol.92 , Issue.1 , pp. 411-417
    • Tsutsumi, K.1    Inoue, Y.2    Shima, A.3    Iwasaki, K.4    Kawamura, M.5    Murase, T.6
  • 93
    • 0031444175 scopus 로고    scopus 로고
    • Antiatherogenic effects of a novel lipoprotein lipase-enhancing agent in cholesterol-fed New Zealand white rabbits
    • Chiba T, Miura S, Sawamura F et al.: Antiatherogenic effects of a novel lipoprotein lipase-enhancing agent in cholesterol-fed New Zealand white rabbits. Arterioscler. Thromb. Vasc. Biol. 17(11), 2601-2608 (1997).
    • (1997) Arterioscler. Thromb. Vasc. Biol , vol.17 , Issue.11 , pp. 2601-2608
    • Chiba, T.1    Miura, S.2    Sawamura, F.3
  • 94
    • 13444312279 scopus 로고    scopus 로고
    • Gene therapy for genetic lipoprotein lipase deficiency: From promise to practice
    • Nierman MC, Rip J, Twisk J et al.: Gene therapy for genetic lipoprotein lipase deficiency: from promise to practice. Neth. J. Med. 63(1), 14-19 (2005).
    • (2005) Neth. J. Med , vol.63 , Issue.1 , pp. 14-19
    • Nierman, M.C.1    Rip, J.2    Twisk, J.3
  • 95
    • 0034050904 scopus 로고    scopus 로고
    • Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector
    • Kay MA, Manno CS, Ragni MV et al.: Evidence for gene transfer and expression of factor IX in haemophilia B patients treated with an AAV vector. Nat. Genet. 24(3), 257-261 (2000).
    • (2000) Nat. Genet , vol.24 , Issue.3 , pp. 257-261
    • Kay, M.A.1    Manno, C.S.2    Ragni, M.V.3
  • 96
    • 4544326444 scopus 로고    scopus 로고
    • Long-term correction of murine lipoprotein lipase deficiency with AAV1-mediated gene transfer of the naturally occurring LPL(S447X) beneficial mutation
    • Ross CJ, Twisk J, Meulenberg JM et al.: Long-term correction of murine lipoprotein lipase deficiency with AAV1-mediated gene transfer of the naturally occurring LPL(S447X) beneficial mutation. Hum. Gene Ther. 15(9), 906-919 (2004).
    • (2004) Hum. Gene Ther , vol.15 , Issue.9 , pp. 906-919
    • Ross, C.J.1    Twisk, J.2    Meulenberg, J.M.3
  • 97
    • 26244445992 scopus 로고    scopus 로고
    • Complete rescue of lipoprotein lipase-deficient mice by somatic gene transfer of the naturally occurring LPLS447X beneficial mutation
    • Ross CJ, Liu G, Kuivenhoven JA et al.: Complete rescue of lipoprotein lipase-deficient mice by somatic gene transfer of the naturally occurring LPLS447X beneficial mutation. Arterioscler. Thromb. Vasc. Biol. 25(10), 2143-2150 (2005).
    • (2005) Arterioscler. Thromb. Vasc. Biol , vol.25 , Issue.10 , pp. 2143-2150
    • Ross, C.J.1    Liu, G.2    Kuivenhoven, J.A.3
  • 98
    • 22744434640 scopus 로고    scopus 로고
    • Antisense oligonucleotides as therapeutics for hyperlipidaemias
    • Crooke RM: Antisense oligonucleotides as therapeutics for hyperlipidaemias. Expert Opin. Biol. Ther. 5(7), 907-917 (2005).
    • (2005) Expert Opin. Biol. Ther , vol.5 , Issue.7 , pp. 907-917
    • Crooke, R.M.1
  • 99
    • 34547868506 scopus 로고    scopus 로고
    • Akdim.F, El Harchaoui K, Stroes ES, Kastelein JJ: Antisense apolipoprotein B-100 as novel treatment for hypercholesterolemia: focus on ISIS 301012. Future Lipidol. 2(4), 387-393 (2007).
    • Akdim.F, El Harchaoui K, Stroes ES, Kastelein JJ: Antisense apolipoprotein B-100 as novel treatment for hypercholesterolemia: focus on ISIS 301012. Future Lipidol. 2(4), 387-393 (2007).
  • 100
    • 48749107147 scopus 로고    scopus 로고
    • ApoC-III antisense oligonucleotides reduce liver mRNA and serum triglyceride levels in hypertriglyceridemic rats
    • Presented at:, San Diego, CA, USA June 10-15
    • Subramaniam A, Lemonidis KM, Graham MJ, Whipple CP, Crooke RM: ApoC-III antisense oligonucleotides reduce liver mRNA and serum triglyceride levels in hypertriglyceridemic rats. Presented at: American Diabetes Association. Annual Meeting. San Diego, CA, USA June 10-15 2005.
    • (2005) American Diabetes Association. Annual Meeting
    • Subramaniam, A.1    Lemonidis, K.M.2    Graham, M.J.3    Whipple, C.P.4    Crooke, R.M.5
  • 101
    • 19944431083 scopus 로고    scopus 로고
    • Inherited apolipoprotein A-V deficiency in severe hypertriglyceridemia
    • Priore Oliva C, Pisciotta L, Li VG et al.: Inherited apolipoprotein A-V deficiency in severe hypertriglyceridemia. Arterioscler. Thromb. Vasc. Biol. 25(2), 411-417 (2005).
    • (2005) Arterioscler. Thromb. Vasc. Biol , vol.25 , Issue.2 , pp. 411-417
    • Priore Oliva, C.1    Pisciotta, L.2    Li, V.G.3
  • 102
    • 26444617632 scopus 로고    scopus 로고
    • Apoa5 Q139X truncation predisposes to late-onset hyperchylomicronernia due to lipoprotein lipase impairment
    • Marcais C, Verges B, Charriere S et al.: Apoa5 Q139X truncation predisposes to late-onset hyperchylomicronernia due to lipoprotein lipase impairment. J. Clin. Invest. 115(10), 2862-2869 (2005).
    • (2005) J. Clin. Invest , vol.115 , Issue.10 , pp. 2862-2869
    • Marcais, C.1    Verges, B.2    Charriere, S.3
  • 103
    • 33645519101 scopus 로고    scopus 로고
    • APOA5 and triglyceride metabolism, lesson from human APOA5 deficiency
    • Calandra S, Priore Oliva C, Tarugi P, Bertolini S: APOA5 and triglyceride metabolism, lesson from human APOA5 deficiency. Curr. Opin. Lipidol. 17(2), 122-127 (2006).
    • (2006) Curr. Opin. Lipidol , vol.17 , Issue.2 , pp. 122-127
    • Calandra, S.1    Priore Oliva, C.2    Tarugi, P.3    Bertolini, S.4
  • 104
    • 40349113281 scopus 로고    scopus 로고
    • Hypertriglyceridaemia and low plasma HDL in a patient with apolipoprotein A-V deficiency due to a novel mutation in the APOA5 gene
    • Prioie Oliva C, Carubbi F, Schaap FG, Bertolini S, Calandra S: Hypertriglyceridaemia and low plasma HDL in a patient with apolipoprotein A-V deficiency due to a novel mutation in the APOA5 gene. J. Intern. Med. 263(4), 450-458 (2008).
    • (2008) J. Intern. Med , vol.263 , Issue.4 , pp. 450-458
    • Prioie Oliva, C.1    Carubbi, F.2    Schaap, F.G.3    Bertolini, S.4    Calandra, S.5
  • 105
    • 0023522662 scopus 로고
    • Apolipoprotein CIISt. Michael. Familial apolipoprotein CII deficiency associated with premature vascular disease
    • Connelly PW, Maguire G.F. Little JA: Apolipoprotein CIISt. Michael. Familial apolipoprotein CII deficiency associated with premature vascular disease. J. Clin. Invest. 80(6), 1597-1606 (1987).
    • (1987) J. Clin. Invest , vol.80 , Issue.6 , pp. 1597-1606
    • Connelly, P.W.1    Maguire, G.F.2    Little, J.A.3
  • 106
    • 0026066446 scopus 로고
    • An apolipoprotein CII mutation, CIILys19-Thr identified in patients with hyperlipidemia
    • Hegele RA, Connelly PW, Maguire GF et al.: An apolipoprotein CII mutation, CIILys19-Thr identified in patients with hyperlipidemia. Dis. Markers 9(2), 73-80 (1991).
    • (1991) Dis. Markers , vol.9 , Issue.2 , pp. 73-80
    • Hegele, R.A.1    Connelly, P.W.2    Maguire, G.F.3
  • 107
    • 0028167871 scopus 로고
    • Apolipoprorein CII-Padova (Tyr37-->stop) as a cause of chylomicronaemia in an Italian kindred from Siculiana
    • Tuzgol S, Bijvoet SM, Bruin T, Kastelein JJ, Hayden MR: Apolipoprorein CII-Padova (Tyr37-->stop) as a cause of chylomicronaemia in an Italian kindred from Siculiana. J. Med. Genet. 31(8), 622-626 (1994).
    • (1994) J. Med. Genet , vol.31 , Issue.8 , pp. 622-626
    • Tuzgol, S.1    Bijvoet, S.M.2    Bruin, T.3    Kastelein, J.J.4    Hayden, M.R.5
  • 108
    • 0034647574 scopus 로고    scopus 로고
    • Familial chylomicronemia caused by a novel type of mutation in the APOE-CI-CIV-CII gene cluster encompassing both the APOCIIgene and the first APOCIV gene mutation: APOCII-CIV (Nijmegen)
    • de Graaf J, Hoffer MJ, Stuyt PM, Frants RR, Stalenhoef AF: Familial chylomicronemia caused by a novel type of mutation in the APOE-CI-CIV-CII gene cluster encompassing both the APOCIIgene and the first APOCIV gene mutation: APOCII-CIV (Nijmegen). Biochem. Biopbys. Res. Commun. 273(3), 1084-1087 (2000).
    • (2000) Biochem. Biopbys. Res. Commun , vol.273 , Issue.3 , pp. 1084-1087
    • de Graaf, J.1    Hoffer, M.J.2    Stuyt, P.M.3    Frants, R.R.4    Stalenhoef, A.F.5


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