Therapeutic response to medium-chain triglycerides and ω-3 fatty acids in a patient with the familial chylomicronemia syndrome

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 17, Issue 7, 1997, Pages 1400-1406

  Rouis, Mustapha ^a   Dugi, Klaus A ^a   Previato, Lorenzo ^a   Patterson, Amy P ^a   Brunzell, John D ^b   Brewer, H Bryan ^a   Santamarina Fojo, Silvia ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^b UNIVERSITY OF WASHINGTON   (United States)

Author keywords

Familial chylomicronemia; Hypertriglyceridemia; Lipoprotein lipase; Medium chain triglyceride; 3 fatty acids

Indexed keywords

CHYLOMICRON; LIPOPROTEIN LIPASE; MEDIUM CHAIN TRIACYLGLYCEROL; OMEGA 3 FATTY ACID;

ARTICLE; CASE REPORT; CHILD; DRUG RESPONSE; ENZYME ACTIVITY; FAMILIAL DISEASE; FEMALE; HUMAN; HYPERLIPOPROTEINEMIA TYPE 1; LIPOLYSIS; PRIORITY JOURNAL; RNA ANALYSIS; TREATMENT OUTCOME;

EID: 0030804675     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.17.7.1400     Document Type: Article

References (8)

1. Brunzell JD. Familial lipoprotein lipase deficiency and other causes of the chylomicronemia syndrome. In: Scriver CR, Beaudet AL, Sly WS, Valle D, eds. The Metabolic and Molecular Bases of Inherited Disease. New York, NY: McGraw-Hill Inc; 1995:1913-1932.
2. Chait A, Iverius P-H, Brunzell JD. Lipoprotein lipase secretion by human monocyte-derived macrophages. J Clin Invest. 1982;69:490-493.
3. Havel RJ, Kane JP, Kashyap ML. Interchange of apolipoproteins between chylomicrons and high density lipoproteins during alimentary lipemia in man. J Clin Invest. 1973;52:32-38.
4. Wion KL, Kirchgessner TG, Lusis AJ, Schotz MC, Lawn RM. Human lipoprotein lipase complementary DNA sequence. Science. 1987;235:1638-1641.
5. Deeb SS, Peng RL. Structure of the human lipoprotein lipase gene. Biochemistry. 1989;28:4131-4135.
6. Kirchgessner TG, Chuat JC, Heinzmann C, Etienne J, Guilhot S, Svenson K, Ameis D, Pilon C, d'Auriol L, Andalibi A, Schotz MC, Galibert F, Lewis AJ. Organization of the human lipoprotein lipase gene and evolution of the lipase gene family. Proc Natl Acad Sci U S A. 1989;86:9647-9651.
7. Fojo SS, Brewer HB Jr. The familial hyperchylomicronemia syndrome. JAMA. 1991;256:904-908.
8. Breckenridge WC, Little JA, Steiner G, Chow A, Poapst M. Hypertriglyceridemia associated with deficiency of apolipoprotein C-II. N Engl J Med. 1978;298:1265-1273.