Suppression of acute proinflammatory cytokine and chemokine upregulation by post-injury administration of a novel small molecule improves long-term neurologic outcome in a mouse model of traumatic brain injury

Journal of Neuroinflammation

Volumn 5, Issue , 2008, Pages

  Lloyd, Eric ^a   Somera Molina, Kathleen ^a,b   Van Eldik, Linda J ^b   Watterson, D Martin ^b   Wainwright, Mark S ^a,b,c  

^a CHILDREN'S MEMORIAL HOSPITAL   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c CHILDREN S MEMORIAL RESEARCH CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMOKINE; CYTOKINE; INTERLEUKIN 1BETA; INTERLEUKIN 6; MINOZAC; MONOCYTE CHEMOTACTIC PROTEIN 1; SMALL MOLECULE TRANSPORT AGENT; TUMOR NECROSIS FACTOR ALPHA; CCL2 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; ASTROCYTE; BRAIN EDEMA; BRAIN LEVEL; CELL ACTIVATION; CONTROLLED STUDY; EXPERIMENTAL STUDY; GLIA CELL; MAZE TEST; MORBIDITY; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PROGNOSIS; TARGET CELL; TRAUMATIC BRAIN INJURY; UPREGULATION; WATER CONTENT; ANIMAL; BLOOD; BRAIN CORTEX; BRAIN INJURY; DISEASE MODEL; DRUG ANTAGONISM; GENETICS; HIPPOCAMPUS; INFLAMMATION; MALE; PATHOPHYSIOLOGY; PHYSIOLOGY; UNITED STATES;

ANIMALS; BRAIN INJURIES; CEREBRAL CORTEX; CHEMOKINE CCL2; CHEMOKINES; CYTOKINES; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; INFLAMMATION; INTERLEUKIN-1BETA; INTERLEUKIN-6; MALE; MICE; TUMOR NECROSIS FACTOR-ALPHA; UNITED STATES; UP-REGULATION;

EID: 48449095239     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/1742-2094-5-28     Document Type: Article

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