Glial activation links early-life seizures and long-term neurologic dysfunction: Evidence using a small molecule inhibitor of proinflammatory cytokine upregulation

Epilepsia

Volumn 48, Issue 9, 2007, Pages 1785-1800

  Somera Molina, Kathleen C ^a,b   Robin, Beverley ^b   Somera, Cherie Ann ^b   Anderson, Christopher ^b   Stine, Christy ^b   Koh, Sookyong ^b   Behanna, Heather A ^b   Van Eldik, Linda J ^b   Watterson, D Martin ^b   Wainwright, Mark S ^b,c  

^a NORTHWESTERN UNIVERSITY   (United States)

^b NORTHWESTERN UNIVERSITY   (United States)

^c CHILDREN'S MEMORIAL HOSPITAL   (United States)

Author keywords

Glia; Glutamate; Neuroinflammation; Newborn; Seizures

Indexed keywords

CLUSTERIN; CYTOKINE; CYTOKINE RECEPTOR ANTAGONIST; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERLEUKIN 1BETA; KAINIC ACID; MINOZAC; PROTEIN S100B; SODIUM CHLORIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BEHAVIOR; CELL ACTIVATION; CONTROLLED STUDY; DISEASE PREDISPOSITION; GLIA CELL; GROUPS BY AGE; HIPPOCAMPUS; MALE; NEUROLOGIC DISEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; SEIZURE; SEIZURE SUSCEPTIBILITY; UPREGULATION; WESTERN BLOTTING;

AGE FACTORS; AMINO ACID TRANSPORT SYSTEM X-AG; ANIMALS; ASTROCYTES; BLOTTING, WESTERN; CLUSTERIN; COMPLEMENT FACTOR H; CYTOKINES; DISEASE MODELS, ANIMAL; DISEASE SUSCEPTIBILITY; FLUORESCENT ANTIBODY TECHNIQUE; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; INFLAMMATION; KAINIC ACID; MALE; MICROGLIA; NEUROGLIA; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SEIZURES; SEVERITY OF ILLNESS INDEX; UP-REGULATION;

EID: 34548405715     PISSN: 00139580     EISSN: 15281167     Source Type: Journal    
DOI: 10.1111/j.1528-1167.2007.01135.x     Document Type: Article

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