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Volumn 280, Issue 2, 2004, Pages 1010-1017

Nature, significance, and mechanisms of electrical heterogeneities in ventricle

Author keywords

Action potential duration; Electrical coupling; Gap junctions; M cell

Indexed keywords

CONNEXIN 43; ION CHANNEL; UNCOUPLING PROTEIN;

EID: 4844229636     PISSN: 0003276X     EISSN: None     Source Type: Journal    
DOI: 10.1002/ar.a.20103     Document Type: Conference Paper
Times cited : (28)

References (49)
  • 1
    • 0037995732 scopus 로고    scopus 로고
    • Transmural heterogeneity of the action potential configuration in the feline left ventricle
    • Aiba T, Shimizu W, Inagaki M, Hidaka I, Tatewaki T, Sunagawa K. 2003. Transmural heterogeneity of the action potential configuration in the feline left ventricle. Circ J 67:449-454.
    • (2003) Circ J , vol.67 , pp. 449-454
    • Aiba, T.1    Shimizu, W.2    Inagaki, M.3    Hidaka, I.4    Tatewaki, T.5    Sunagawa, K.6
  • 2
    • 0034473170 scopus 로고    scopus 로고
    • Cellular basis for dispersion of repolarization underlying reentrant arrhythmias
    • Akar FG, Laurita KR, Rosenbaum DS. 2000. Cellular basis for dispersion of repolarization underlying reentrant arrhythmias. J Electrocardiol 33(Suppl):23-31.
    • (2000) J Electrocardiol , vol.33 , Issue.SUPPL. , pp. 23-31
    • Akar, F.G.1    Laurita, K.R.2    Rosenbaum, D.S.3
  • 3
    • 0034880524 scopus 로고    scopus 로고
    • Optical measurement of cell-to-cell coupling in intact heart using subthreshold electrical stimulation
    • Akar FG, Roth BJ, Rosenbaum DS. 2001. Optical measurement of cell-to-cell coupling in intact heart using subthreshold electrical stimulation. Am J Physiol Heart Circ Physiol 281:H533-H542.
    • (2001) Am J Physiol Heart Circ Physiol , vol.281
    • Akar, F.G.1    Roth, B.J.2    Rosenbaum, D.S.3
  • 4
    • 0037066015 scopus 로고    scopus 로고
    • Unique topographical distribution of m cells underlies reentrant mechanism of torsade de pointes in the long-QT syndrome
    • Akar FG, Yan GX, Antzelevitch C, Rosenbaum DS. 2002. Unique topographical distribution of m cells underlies reentrant mechanism of torsade de pointes in the long-QT syndrome. Circulation 105:1247-1253.
    • (2002) Circulation , vol.105 , pp. 1247-1253
    • Akar, F.G.1    Yan, G.X.2    Antzelevitch, C.3    Rosenbaum, D.S.4
  • 5
    • 0141707855 scopus 로고    scopus 로고
    • Transmural electrophysiological heterogeneities underlying arrhythmogenesis in heart failure
    • Akar FG, Rosenbaum DS. 2003. Transmural electrophysiological heterogeneities underlying arrhythmogenesis in heart failure. Circ Res 93:638-645.
    • (2003) Circ Res , vol.93 , pp. 638-645
    • Akar, F.G.1    Rosenbaum, D.S.2
  • 6
    • 0029844535 scopus 로고    scopus 로고
    • Regional differences in electrophysiological properties of epicardium, midmyocardium, and endocardium: In vitro and in vivo correlations
    • Anyukhovsky EP, Sosunov EA, Rosen MR. 1996. Regional differences in electrophysiological properties of epicardium, midmyocardium, and endocardium: in vitro and in vivo correlations. Circulation 94:1981-1988.
    • (1996) Circulation , vol.94 , pp. 1981-1988
    • Anyukhovsky, E.P.1    Sosunov, E.A.2    Rosen, M.R.3
  • 7
    • 0034999429 scopus 로고    scopus 로고
    • Regional nonuniformity of normal adult human left ventricle
    • Bogaert J, Rademakers FE. 2001. Regional nonuniformity of normal adult human left ventricle. Am J Physiol 280:H610-H620.
    • (2001) Am J Physiol , vol.280
    • Bogaert, J.1    Rademakers, F.E.2
  • 8
    • 0018387132 scopus 로고
    • How does adrenaline accelerate the heart?
    • Brown HF, DiFrancesco D, Noble SJ. 1979. How does adrenaline accelerate the heart? Nature 280:235-236.
    • (1979) Nature , vol.280 , pp. 235-236
    • Brown, H.F.1    DiFrancesco, D.2    Noble, S.J.3
  • 11
    • 0029023244 scopus 로고
    • Electrophysiologic characteristics of cells spanning the left ventricular wall of human heart: Evidence for presence of M cells
    • Drouin E, Charpentier F, Gauthier C, Laurent K, Le Marec H. 1995. Electrophysiologic characteristics of cells spanning the left ventricular wall of human heart: evidence for presence of M cells. J Am Coll Cardiol 26:185-192.
    • (1995) J Am Coll Cardiol , vol.26 , pp. 185-192
    • Drouin, E.1    Charpentier, F.2    Gauthier, C.3    Laurent, K.4    Le Marec, H.5
  • 13
    • 0347418930 scopus 로고    scopus 로고
    • Pharmacological modulation of cardiac gap junctions to enhance cardiac conduction: Evidence supporting a novel target for antiarrhythmic therapy
    • Eloff BC, Gilat E, Wan X, Rosenbaum DS. 2003. Pharmacological modulation of cardiac gap junctions to enhance cardiac conduction: evidence supporting a novel target for antiarrhythmic therapy. Circulation 108:3157-3163.
    • (2003) Circulation , vol.108 , pp. 3157-3163
    • Eloff, B.C.1    Gilat, E.2    Wan, X.3    Rosenbaum, D.S.4
  • 14
    • 2442503737 scopus 로고    scopus 로고
    • Epicardial activation of left ventricular wall prolongs qt interval and transmural dispersion of repolarization, implications for biventricular pacing
    • in press
    • Fish JM, Di Diego JM, Nesterenko V, Antzelevitch C. 2004. Epicardial activation of left ventricular wall prolongs qt interval and transmural dispersion of repolarization, implications for biventricular pacing. Circulation (in press).
    • (2004) Circulation
    • Fish, J.M.1    Di Diego, J.M.2    Nesterenko, V.3    Antzelevitch, C.4
  • 16
    • 0032760125 scopus 로고    scopus 로고
    • The relation of contractile function to myocardial perfusion: Perfusion-contraction match and mismatch
    • Heusch G, Schulz R. 1999. The relation of contractile function to myocardial perfusion: perfusion-contraction match and mismatch. Herz 24:509-514.
    • (1999) Herz , vol.24 , pp. 509-514
    • Heusch, G.1    Schulz, R.2
  • 17
    • 0020587235 scopus 로고
    • Characteristics and possible mechanisms of ventricular arrhythmia dependent on the dispersion of action potential durations
    • Kuo C, Munakata K, Reddy CP, Surawicz B. 1983. Characteristics and possible mechanisms of ventricular arrhythmia dependent on the dispersion of action potential durations. Circulation 67:1356-1357.
    • (1983) Circulation , vol.67 , pp. 1356-1357
    • Kuo, C.1    Munakata, K.2    Reddy, C.P.3    Surawicz, B.4
  • 18
    • 0037418912 scopus 로고    scopus 로고
    • Transmural heterogeneity of calcium handling in canine
    • Laurita KR, Katra R, Wible B, Wan XP, Koo MH. 2003. Transmural heterogeneity of calcium handling in canine. Circ Res 92:668-675.
    • (2003) Circ Res , vol.92 , pp. 668-675
    • Laurita, K.R.1    Katra, R.2    Wible, B.3    Wan, X.P.4    Koo, M.H.5
  • 19
    • 0024453193 scopus 로고
    • Cellular uncoupling can unmask dispersion of action potential duration in ventricular myocardium: A computer modeling study
    • Lesh MD, Pring M, Spear JF. 1989. Cellular uncoupling can unmask dispersion of action potential duration in ventricular myocardium: a computer modeling study. Circ Res 65:1426-1440.
    • (1989) Circ Res , vol.65 , pp. 1426-1440
    • Lesh, M.D.1    Pring, M.2    Spear, J.F.3
  • 20
    • 0036352059 scopus 로고    scopus 로고
    • Transmural action potential and ionic current remodeling in ventricles of failing canine hearts
    • Li GR, Lau CP, Ducharme A, Tardif JC, Nattel S. 2002a. Transmural action potential and ionic current remodeling in ventricles of failing canine hearts. Am J Physiol Heart Circ Physiol 283:H1031-H1041.
    • (2002) Am J Physiol Heart Circ Physiol , vol.283
    • Li, G.R.1    Lau, C.P.2    Ducharme, A.3    Tardif, J.C.4    Nattel, S.5
  • 22
    • 0027460628 scopus 로고
    • Ionic bases for electrophysiological distinctions among epicardial, midmyocardial, and endocardial myocytes from the free wall of the canine left ventricle
    • Liu D-W, Gintant GA, Antzelevitch C. 1993. Ionic bases for electrophysiological distinctions among epicardial, midmyocardial, and endocardial myocytes from the free wall of the canine left ventricle. Circ Res 72:671-687.
    • (1993) Circ Res , vol.72 , pp. 671-687
    • Liu, D.-W.1    Gintant, G.A.2    Antzelevitch, C.3
  • 23
    • 0028881535 scopus 로고
    • Ks contributes to the longer action potential of the M cell
    • Ks contributes to the longer action potential of the M cell. Circ Res 76:351-365.
    • (1995) Circ Res , vol.76 , pp. 351-365
    • Liu, D.-W.1    Antzelevitch, C.2
  • 24
    • 0037205321 scopus 로고    scopus 로고
    • Connexin43 and connexin45 form heteromeric gap junction channels in which individual components determine permeability and regulation
    • Martinez AD, Hayrapetyan V, Moreno AP, Beyer EC. 2002. Connexin43 and connexin45 form heteromeric gap junction channels in which individual components determine permeability and regulation. Circ Res 90:1100-1107.
    • (2002) Circ Res , vol.90 , pp. 1100-1107
    • Martinez, A.D.1    Hayrapetyan, V.2    Moreno, A.P.3    Beyer, E.C.4
  • 25
    • 0033985607 scopus 로고    scopus 로고
    • 2+ in left ventricular myocyte sub-types from rabbits with heart failure
    • 2+ in left ventricular myocyte sub-types from rabbits with heart failure. Cardiovasc Res 45:397-409.
    • (2000) Cardiovasc Res , vol.45 , pp. 397-409
    • McIntosh, M.A.1    Cobbe, S.M.2    Smith, G.L.3
  • 26
    • 0032851539 scopus 로고    scopus 로고
    • Characterization of conduction in the ventricles of normal and heterozygous Cx43 knockout mice using optical mapping
    • Morley GE, Vaidya D, Samie FH, Lo C, Delmar M, Jalife J. 1999. Characterization of conduction in the ventricles of normal and heterozygous Cx43 knockout mice using optical mapping. J Cardiovasc Electrophysiol 10:1361-1375.
    • (1999) J Cardiovasc Electrophysiol , vol.10 , pp. 1361-1375
    • Morley, G.E.1    Vaidya, D.2    Samie, F.H.3    Lo, C.4    Delmar, M.5    Jalife, J.6
  • 28
    • 4744341926 scopus 로고    scopus 로고
    • Altered connexin43 expression produces arrhythmia substrate in heart failure
    • in press
    • Poelzing S, Rosenbaum DS. 2004. Altered connexin43 expression produces arrhythmia substrate in heart failure. Am J Physiol Heart Circ Physiol (in press).
    • (2004) Am J Physiol Heart Circ Physiol
    • Poelzing, S.1    Rosenbaum, D.S.2
  • 29
    • 1942533420 scopus 로고    scopus 로고
    • Heterogeneous connexin43 expression produces electrophysiological heterogeneities across ventricular wall
    • Poelzing S, Akar FG, Baron E, Rosenbaum DS. 2004. Heterogeneous connexin43 expression produces electrophysiological heterogeneities across ventricular wall. Am J Physiol Heart Circ Physiol 286: H2001-H2009.
    • (2004) Am J Physiol Heart Circ Physiol , vol.286
    • Poelzing, S.1    Akar, F.G.2    Baron, E.3    Rosenbaum, D.S.4
  • 30
    • 0344033816 scopus 로고    scopus 로고
    • Myocardial infarction causes increased expression but decreased activity of the myocardial Na+-Ca2+ exchanger in the rabbit
    • Quinn FR, Currie S, Duncan AM, Miller S, Sayeed R, Cobbe SM, Smith GL. 2003. Myocardial infarction causes increased expression but decreased activity of the myocardial Na+-Ca2+ exchanger in the rabbit. J Physiol 553:229-242.
    • (2003) J Physiol , vol.553 , pp. 229-242
    • Quinn, F.R.1    Currie, S.2    Duncan, A.M.3    Miller, S.4    Sayeed, R.5    Cobbe, S.M.6    Smith, G.L.7
  • 31
    • 0035867045 scopus 로고    scopus 로고
    • Regulation of KChIP2 potassium channel β subunit gene expression underlies the gradient of transient outward current in canine and human ventricle
    • Lond
    • Rosati B, Pan ZM, Lypen S, Wang HS, Cohen I, Dixon JE, McKinnon D. 2001. Regulation of KChIP2 potassium channel β subunit gene expression underlies the gradient of transient outward current in canine and human ventricle. J Physiol (Lond) 533:119-125.
    • (2001) J Physiol , vol.533 , pp. 119-125
    • Rosati, B.1    Pan, Z.M.2    Lypen, S.3    Wang, H.S.4    Cohen, I.5    Dixon, J.E.6    McKinnon, D.7
  • 32
    • 0023502646 scopus 로고
    • A model study of the effects of the discrete cellular structure on electrical propagation in cardiac tissue
    • Rudy Y, Quan W. 1987. A model study of the effects of the discrete cellular structure on electrical propagation in cardiac tissue. Circ Res 61:815-823.
    • (1987) Circ Res , vol.61 , pp. 815-823
    • Rudy, Y.1    Quan, W.2
  • 34
    • 0030819433 scopus 로고    scopus 로고
    • Sodium channel block with mexiletine is effective in reducing dispersion of repolarization and preventing torsade de pointes in LQT2 and LQT3 models of the long-QT syndrome
    • Shimizu W, Antzelevitch C. 1997. Sodium channel block with mexiletine is effective in reducing dispersion of repolarization and preventing torsade de pointes in LQT2 and LQT3 models of the long-QT syndrome. Circulation 96:2038-2047.
    • (1997) Circulation , vol.96 , pp. 2038-2047
    • Shimizu, W.1    Antzelevitch, C.2
  • 35
    • 0025829410 scopus 로고
    • A subpopulation of cells with unique electrophysiological properties in the deep subepicardium of the canine ventricle: The M cell
    • Sicouri S, Antzelevitch C. 1991. A subpopulation of cells with unique electrophysiological properties in the deep subepicardium of the canine ventricle: the M cell. Circ Res 68:1729-1741.
    • (1991) Circ Res , vol.68 , pp. 1729-1741
    • Sicouri, S.1    Antzelevitch, C.2
  • 36
  • 38
    • 0037704231 scopus 로고    scopus 로고
    • Impulse propagation in synthetic strands of neonatal cardiac myocytes with genetically reduced levels of connexin43
    • Thomas SP, Kucera JP, Bircher-Lehmann L, Rudy Y, Saffitz JE, Kléber AG. 2003. Impulse propagation in synthetic strands of neonatal cardiac myocytes with genetically reduced levels of connexin43. Circ Res 92:1209-1216.
    • (2003) Circ Res , vol.92 , pp. 1209-1216
    • Thomas, S.P.1    Kucera, J.P.2    Bircher-Lehmann, L.3    Rudy, Y.4    Saffitz, J.E.5    Kléber, A.G.6
  • 39
    • 1442359119 scopus 로고    scopus 로고
    • Slow conduction and enhanced anisotropy increase the propensity for ventricular tachyarrhythmias in adult mice with induced deletion of connexin43
    • van Rijen HV, Eckardt D, Degen J, Theis M, Ott T, Willecke K, Jongsma HJ, Opthof T, de Bakker JM. 2004. Slow conduction and enhanced anisotropy increase the propensity for ventricular tachyarrhythmias in adult mice with induced deletion of connexin43. Circulation 109:1048-1055.
    • (2004) Circulation , vol.109 , pp. 1048-1055
    • Van Rijen, H.V.1    Eckardt, D.2    Degen, J.3    Theis, M.4    Ott, T.5    Willecke, K.6    Jongsma, H.J.7    Opthof, T.8    De Bakker, J.M.9
  • 40
    • 0019385897 scopus 로고
    • The origin of the epicardium and the embryonic myocardial circulation in the mouse
    • Virágh S, Challice CE. 1981. The origin of the epicardium and the embryonic myocardial circulation in the mouse. Anat Rec 201:157-168.
    • (1981) Anat Rec , vol.201 , pp. 157-168
    • Virágh, S.1    Challice, C.E.2
  • 41
    • 0033545725 scopus 로고    scopus 로고
    • Ks heterogeneity on action potential duration and its rate dependence: A simulation study
    • Ks heterogeneity on action potential duration and its rate dependence: a simulation study. Circulation 99:2466-2474.
    • (1999) Circulation , vol.99 , pp. 2466-2474
    • Viswanathan, P.C.1    Shaw, R.M.2    Rudy, Y.3
  • 44
    • 0032480753 scopus 로고    scopus 로고
    • Characteristics and distribution of M cells in arterially perfused canine left ventricular wedge preparations
    • Yan GX, Shimizu W, Antzelevitch C. 1998. Characteristics and distribution of M cells in arterially perfused canine left ventricular wedge preparations. Circulation 98:1921-1927.
    • (1998) Circulation , vol.98 , pp. 1921-1927
    • Yan, G.X.1    Shimizu, W.2    Antzelevitch, C.3
  • 45
    • 0033214705 scopus 로고    scopus 로고
    • Heterogeneous changes in K currents in rat ventricles three days after myocardial infarction
    • Yao JA, Jiang M, Fan JS, Zhou YY, Tseng GN. 1999. Heterogeneous changes in K currents in rat ventricles three days after myocardial infarction. Cardiovasc Res 44:132-145.
    • (1999) Cardiovasc Res , vol.44 , pp. 132-145
    • Yao, J.A.1    Jiang, M.2    Fan, J.S.3    Zhou, Y.Y.4    Tseng, G.N.5
  • 46
    • 0346098208 scopus 로고    scopus 로고
    • Noninvasive risk stratification in postinfarction patients with severe left ventricular dysfunction and methodology of the MADIT II noninvasive electrocardiology substudy
    • Zareba W, Moss AJ. 2003. Noninvasive risk stratification in postinfarction patients with severe left ventricular dysfunction and methodology of the MADIT II noninvasive electrocardiology substudy. J Electrocardiol 36(Suppl):101-108.
    • (2003) J Electrocardiol , vol.36 , Issue.SUPPL. , pp. 101-108
    • Zareba, W.1    Moss, A.J.2
  • 47
    • 0034682933 scopus 로고    scopus 로고
    • Pulsatile stretch remodels cell-to-cell communication in cultured myocytes
    • Zhuang JP, Yamada KA, Saffitz JE, Kleber AG. 2000. Pulsatile stretch remodels cell-to-cell communication in cultured myocytes. Circ Res 87:316-322.
    • (2000) Circ Res , vol.87 , pp. 316-322
    • Zhuang, J.P.1    Yamada, K.A.2    Saffitz, J.E.3    Kleber, A.G.4


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