Population structure and epidemiology of toxoplasma gondii

Toxoplasma Gondii

Volumn , Issue , 2007, Pages 49-80

  Darde M L ^a   Ajzenberg, D ^a   Smith, J ^b  

^a UNIVERSITY OF LIMOGES   (France)

^b UNIVERSITY OF LEEDS   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 48349107019     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-012369542-0/50005-2     Document Type: Chapter

References (141)

1. Ajioka J.W., Boothroyd J.C., Brunk B.P., et al. Gene discovery by EST sequencing in Toxoplasma gondii reveals sequences restricted to the Apicomplexa. Genome Res. 1998, 8:18-28.
2. Ajzenberg D., Bañuls A.L., Tibayrenc M., Dardé M.L. Microsatellite analysis of Toxoplasma gondii shows considerable polymorphism structured into two main clonal groups. Intl J. Parasitol. 2002, 32:27-38.
3. Ajzenberg D., Cogné N., Paris L., et al. Genotype of 86 Toxoplasma gondii isolates associated with human congenital toxoplasmosis, and correlation with clinical findings. J. Infect. Dis. 2002, 186:684-689.
4. Ajzenberg D., Bañuls A.L., Su C., et al. Genetic diversity, clonality and sexuality in Toxoplasma gondii. Intl J. Parasitol. 2004, 34:1185-1196.
5. Ajzenberg D., Dumètre A., Dardé M.L. Multiplex PCR for typing strains of Toxoplasma gondii. J. Clin. Microbiol. 2005, 43:1940-1943.
6. Anderson T.J.C., Haubold B., Williams J.T., et al. Microsatellite markers reveal a spectrum of population structures in the malaria parasite. Plasmodium falci-parum. Mol. Biol. Evol. 2000, 17:1467-1482.
7. Aramini J.J., Stephen C., Dubey J.P. Toxoplasma gondii in Vancouver Island cougars (Felis concolor vancouverensis) : serology and oocyst shed-ding. J. Parasitol. 1998, 84:438-440.
8. Asai T., Miura S., Sibley L.D., Okabayashi H., Takeuchi T. Biochemical and molecular char-acterization of nucleoside triphosphate hydrolase isozymes from the parasitic protozoan Toxoplasma gondii. J. Biol. Chem. 1995, 270:11 391-11 397.
9. Aspinall T.V., Joynson D.H., Guy E., Hyde J.E., Sims P.F. The molecular basis of sulfonamide resist-ance in Toxoplasma gondii and implications for the clinical management of toxoplasmosis. J. Infect. Dis. 2002, 185:1637-1643.
10. Aspinall T.V., Guy E.C., Roberts K.E., Joynson D.H.M., Hyde J.E., Sims P.F.G. Molecular evidence for multiple Toxoplasma gondii infections in individ-ual patients in England and Wales: public health implications. Intl J. Parasitol. 2003, 33:97-103.
11. Bahia-Oliveira L.M.G., Jones J.L., Azevedo-Silva J., Alves C.C.F., Oréfice F., Addiss D.G. Highly endemic, waterborne toxoplasmosis in north Rio de Janeiro state,. Brazil. Emerg. Infect. Dis. 2003, 9:55-62.
12. Bañuls A.L., Hide M., Tibayrenc M. Molecular epidemiology and evolutionary genetics of Leishmania parasites. Intl J. Parasitol. 1999, 29:1137-1147.
13. Barragan A., Sibley L.D. Transepithelial migration of Toxoplasma gondii is linked to parasite motility and virulence. J. Exp. Med. 2002, 195:1625-1633.
14. Benenson M.W., Takafuji E.T., Lemon S.M., Greenup R.L., Sulzer A.J. Oocyst-transmitted toxo-plasmosis associated with ingestion of contaminated water. N. Engl. J. Med. 1982, 307:666-669.
15. Beverley J.K.A. Congenital transmission of toxo-plasmosis through successive generations of mice. Nature 1959, 183:1348-1349.
16. Biñas M., Johnson A.M. A polymorphism in a DNA polymerase alpha gene intron differentiates between murine virulent and avirulent strains of Toxoplasma gondii. Intl J. Parasitol. 1998, 28:1033-1040.
17. Blackston C.R., Dubey J.P., Dotson E., et al. High-resolution typing of Toxoplasma gondii using microsatellite loci. J. Parasitol. 2001, 87:1472-1475.
18. Boothroyd J.C., Grigg M.E. Population biol-ogy of Toxoplasma gondii and its relevance to human infection: do different strains cause different disease?. Curr. Opin. Microbiol. 2002, 5:438-442.
19. Boothroyd J.C., Kim S.K., Saeij J., Boyle J. Exploring the host-pathogen interaction through forward, reverse and sideways genetics. Abstract 11, Eighth International Congress on Toxoplasmosis 2005.
20. Bossi P., Caumes E., Paris L., Dardé M.L., Bricaire F. Toxoplasma gondii-associated Guillain-Barré syndrome in an immunocompetent patient. J. Clin. Microbiol. 1998, 36:3724-3725.
21. Bowie W.R., King A.S., Werker D.H., et al. Outbreak of toxoplasmosis associated with munici-pal drinking water. Lancet 1997, 350:173-177.
22. Burnett A.J., Shortt S.G., Isaac-Renton J., King A., Werker D., Bowie W.R. Multiple cases of acquired toxoplasmosis retinitis presenting in an outbreak. Ophthalmology 1998, 105:1032-1037.
23. Carme B., Bissuel F., Ajzenberg D., et al. Severe acquired toxoplasmosis in immunocompetent adult patients in French Guiana. J. Clin. Microbiol. 2002, 40:4037-4044.
24. Cole R.A., Lindsay D.S., Howe D.K., et al. Biological and molecular characterizations of Toxoplasma gondii strains obtained from southern sea otters. (Enhydra lutris nereis) . J. Parasitol. 2000, 86:526-530.
25. Conrad P.A., Miller M.A., Kreuder C., et al. Transmission of Toxoplasma: Clues from the study of sea otters as sentinels of Toxoplasma gondii flow into the marine environment. Intl J. Parasitol. 2005, 35:1155-1168.
26. Costa J.M., Dardé M.L., Assouline B., Vidaud M., Bretagne S. Microsatellite in the beta-tubulin gene of Toxoplasma gondii as a new genetic marker for use in direct screening of amniotic fluids. J. Clin. Microbiol. 1997, 35:2542-2545.
27. Cristina N., Liaud M.F., Santoro F., Oury B., Ambroise-Thomas P. A family of repeated DNA sequences in Toxoplasma gondii: cloning, sequence analysis, and use in strain characterization. Exp. Parasitol. 1991, 73:73-81.
28. Cristina N., Dardé M.L., Boudin C., Tavernier G., Pestre-Alexandre M., Ambroise-Thomas P. A DNA fingerprinting method for individual characterization of Toxoplasma gondii strains: combination with isoenzymatic characters for deter-mination of linka. Parasitol. Res. 1995, 81:32-37.
29. Dao A., Fortier B., Soete M., Plenat F., Dubremetz J.F. Successful reinfection of chronically infected mice by a different Toxoplasma gondii geno-type. Intl J. Parasitol. 2001, 31:63-65.
30. Dardé M.L. Biodiversity in Toxoplasma gondii. Curr. Topics Microbiol. Immunol. 1996, 219:27-41.
31. Dardé M.L. Genetic analysis of the diversity in Toxoplasma gondii. Ann. Ist. Super. Sanità 2004, 40:57-63.
32. Dardé M.L., Bouteille B., Pestre-Alexandre M. Isoenzymic characterization of seven strains of Toxoplasma gondii by isoelectrofocusing in poly-acrylamide gels. Am. J. Trop. Med. Hyg. 1988, 39:551-558.
33. Dardé M.L., Bouteille B., Pestre-Alexandre M. Isoenzyme analysis of 35 Toxoplasma gondii isolates and the biological and epidemiological implications. J. Parasitol. 1992, 78:786-794.
34. Dardé M.L., Villena I., Pinon J.M., Beguinot I. Severe toxoplasmosis caused by a Toxoplasma gondii strain with a new isoenzyme type acquired in French Guyana. J. Clin. Microbiol. 1998, 36:324.
35. da Silva A.V., Pezerico S.B., de Lima V.Y., et al. Genotyping of Toxoplasma gondii strains isolated from dogs with neurological signs. Vet. Parasitol. 2005, 127:23-27.
36. de A.dos Santos C.B., de Carvalho A.C.F.B., Ragozo A.M.A., et al. First isolation and molecular characteriza-tion of Toxoplasma gondii from finishing pigs from São Paulo State,. Brazil. Vet. Parasitol. 2005, 131:207-211.
37. Debord T., Eono P., Rey J.L., Roué R. Les risques infectieux chez les militaires en opération. Méd. Mal. Infect. 1996, 26:402-407.
38. de Sousa S.D., Ajzenberg D., Canada N., et al. Biologic and molecular characterization of Toxoplasma gondii isolates from pigs from Portugal. Vet. Parasitol. 2006, 135:133-136.
39. Diana J., Persat F., Staquet M.J., et al. Migration and maturation of human dendritic cells infected with Toxoplasma gondii depend on parasite strain type. FEMS Immunol. Med. Microbiol. 2004, 42:321-331.
40. Dubey J.P. Duration of immunity to shedding of Toxoplasma gondii oocysts by cats. J. Parasitol. 1995, 81:410-415.
41. Dubey J.P., Shen S.K., Kwok O.C., Thulliez P. Toxoplasmosis in rats (Rattus norvegicus) : congenital transmission to first and second generation offspring and isolation of Toxoplasma gondii from seronega-. Parasitology 1997, 115:9-14.
42. Dubey J.P., Graham D.H., Blackston C.R., et al. Biological and genetic characterisation of Toxoplasma gondii isolates from chickens (Gallus domesticus) from São Paulo, Brazil: unexpected find-ings. Intl J. Parasitol. 2002, 32:99-105.
43. Dubey J.P., Graham D.H., da Silva D.S., Lehmann T., Bahia-Oliveira L.M.G. Toxoplasma gondii isolates of free-ranging chickens from Rio de Janeiro, Brazil: mouse mortality, genotype and oocyst shedding by cats. J. Parasitol. 2003, 89:851-853.
44. Dubey J.P., Navarro I.T., Graham D.H., et al. Characterization of Toxoplasma gondii isolates from free range chickens from Parana. Brazil. Vet. Parasitol. 2003, 117:229-234.
45. Dubey J.P., Graham D.H., Dahl E., et al. Isolation and molecular characterization of Toxoplasma gondii isolates from chickens and ducks from Egypt. Vet. Parasitol. 2003, 114:89-95.
46. Dubey J.P., Venturini M.C., Venturini L., et al. Isolation and genotyping of Toxoplasma gondii from free-ranging chickens from Argentina. J. Parasitol. 2003, 89:1063-1064.
47. Dubey J.P., Graham D.H., Dahl E., et al. Toxoplasma gondii isolates from free-ranging chickens from the United States. J. Parasitol. 2003, 89:1060-1062.
48. Dubey J.P., Levy M.Z., Sreekumar C., et al. Tissue distribution and molecular characterization of chicken isolates of Toxoplasma gondii from Peru. J. Parasitol. 2004, 90:1015-1018.
49. Dubey J.P., Morales E.S., Lehmann T. Isolation and genotyping of Toxoplasma gondii from free-ranging chickens from Mexico. J. Parasitol. 2004, 90:411-413.
50. Dubey J.P., Salant H., Sreekumar C., et al. High prevalence of Toxoplasma gondii in a commercial flock of chickens in Israel, and public health implica-tions of free-range farming. Vet. Parasitol. 2004, 121:317-322.
51. Dubey J.P., Navarro I.T., Sreekumar C., et al. Toxoplasma gondii infections in cats from Parana, Brazil: seroprevalence, tissue distribution, and biologic and genetic characterization of isolates. J. Parasitol. 2004, 90:721-726.
52. Dubey J.P., Graham D.H., de Young R.W., et al. Molecular and biologic characteristics of Toxoplasma gondii isolates from wildlife in the United States. J. Parasitol. 2004, 90:67-71.
53. Dubey J.P., Parnell P.G., Sreekumar C., et al. Biological and molecular characteristics of Toxoplasma gondii isolates from striped skunks (Mephitis mephitis) , Canada goose (Branta canaden-sis) , black-win (Eos cyanogenia) , and cats. (Felis catus) .J. Parasitol. 2004, 90:1171-1174.
54. Dubey J.P., Bhaiyat M.I., de Allie C., et al. Isolation, tissue distribution, and molecular charac-terization of Toxoplasma gondii from chickens in Grenada, West Indies. J. Parasitol. 2005, 91:557-560.
55. Dubey J.P., Karhemere S., Dahl E., et al. First biologic and genetic characterization of Toxoplasma gondii isolates from chickens from Africa (Democratic Republic of Congo, Mali, Burkina Faso, and Ken. J. Parasitol. 2005, 91:69-72.
56. Dubey J.P., Gomez-Marin J.E., Bedoya A., et al. Genetic and biologic characteristics of Toxoplasma gondii isolates in free-range chickens from Colombia, South America. Vet. Parasitol. 2005, 134:67-72.
57. Dubey J.P., Lenhart A., Castillo C.E., et al. Toxoplasma gondii infections in chickens from Venezuela: isolation, tissue distribution, and molecu-lar characterization. J. Parasitol. 2005, 91:1332-1334.
58. Dubey J.P., Lopez B., Alveraz M., Mendoza C., Lehmann T. Isolation, tissue distribution, and molecular characterization of Toxoplasma gondii from free-range chickens from Guatemala. J. Parasitol. 2005, 91:955-957.
59. Dubey J.P., Marcet P.L., Lehmann T. Characterization of Toxoplasma gondii in free-range chickens from Argentina. J. Parasitol. 2005, 91:1335-1339.
60. Dubey J.P., Rajapakse R.P.V.J., Ekanayake D.K., Sreekumar C., Lehmann T. Isolation and molecular characterization of Toxoplasma gondii from chickens from Sri Lanka. J. Parasitol. 2005, 91:1480-1482.
61. Dubey J.P., Edelhofer R., Marcet P.L., et al. Genetic and biologic characteristics of Toxoplasma gondii infections in free-range chickens from Austria. Vet. Parasitol. 2005, 133:299-306.
62. Dubey J.P., Vianna M.C.B., de Sousa S., et al. Characterization of Toxoplasma gondii isolates in free-range chickens from Portugal. J. Parasitol. 2006, 92:184-186.
63. Duncanson P., Terry R.S., Smith J.E., Hide G. High levels of congenital transmission of Toxoplasma gondii in a commercial sheep flock. Intl J. Parasitol. 2001, 31:1699-1703.
64. Dunn A., Smith J.E. Microsporidian life cycles and diversity: the relationship between viru-lence and transmission. Microbes Infect. 2001, 3:381-388.
65. Fazaeli A., Carter P.E., Dardé M.L., Pennington TH. Molecular typing of Toxoplasma gondii strains by GRA6 gene sequence analysis. Intl J. Parasitol. 2000, 30:637-642.
66. Fazaeli A., Carter P.E., Pennington T.H. Intergenic spacer (IGS) polymorphism: a new genetic marker for differentiation of Toxoplasma gondii strains and. Neospora caninum. J. Parasitol. 2000, 86:716-723.
67. Ferdig M.T., Su X.Z. Microsatellite markers and genetic mapping in Plasmodium falciparum. Parasitol. Today 2000, 16:307-312.
68. Ferguson D.J.P. Toxoplasma gondii and sex: essential or optional extra?. Trends Parasitol. 2002, 18:355-359.
69. Ferreira A.M., Vitor R.W.A., Carneiro A.C.A.V., Brandão G.P., Melo M.N. Genetic variability of Brazilian Toxoplasma gondii strains detected by random amplified polymorphic DNA-polymerase chain reaction (RAPD-PCR) and simple sequen anchored-PCR (SSR-PCR). Infect. Genet. Evol. 2004, 4:131-142.
70. Ferreira A.M., Vitor R.W.A., Gazzinelli R.T., Melo M.N. Genetic analysis of natural recombinant Brazilian Toxoplasma gondii strains by multilocus PCR-RFLP. Infect. Genet. Evol. 2006, 6:22-31.
71. Frenkel J.K., Dubey J.P., Miller N.L. Toxoplasma gondii in cats: fecal stages identified as coccidian oocysts. Science 1970, 167:893-896.
72. Fuentes I., Rubio J.M., Ramirez C., Alvar J. Genotypic characterization of Toxoplasma gondii strains associated with human toxoplasmosis in Spain: direct analysis from clinical samples. J. Clin. Microbiol. 2001, 39:1566-1570.
73. Fuentes I., Montoya A., Garcia-Perez A.L., et al. Genotypic characterization of Toxoplasma gondii isolates from ovine in Spain. Abstract 238, MEEGID VII 2004.
74. Fuentes I., Rodriguez M., Ladron de Guevara C., et al. Genotypic characterization of Toxoplasma gondii strains associated with human toxoplasmosis in Spain. Abstract 237, MEEGID VII 2004.
75. Fux B., Rodrigues C.V., Portela R.W., et al. Role of cytokines and major histocompatibility complex restriction in mouse resistance to infection with a natural recombinant strain (type I-III) of Toxoplas. Infect. Immun. 2003, 71:6392-6401.
76. Gallego C., Saavedra-Matiz C., Gomez-Marin J.E. Direct genotyping of animal and human isolates from Colombia (South America). Acta Trop. 2006, 97:161-167.
77. Gardener P.J., Howells R.E. Isoenzyme varia-tion in leishmanial parasites. J. Protozool. 1972, 19:47-48.
78. Gavrilescu L.C., Denkers E.Y. IFN-gamma overproduction and high level apoptosis are associ-ated with high but not low virulence Toxoplasma gondii infection. J. Immunol. 2001, 167:902-909.
79. Gilbert R.E., Dunn D.T., Lightman S., et al. Incidence of symptomatic Toxoplasma eye disease: aetiology and public health implications. Epidemiol. Infect. 1999, 123:283-289.
80. Grigg M.E., Boothroyd J.C. Rapid identifica-tion of virulent type I strains of the protozoan pathogen Toxoplasma gondii by PCR-Restriction fragment length polymorphism analysis at the B. J. Clin. Microbiol. 2001, 39:398-400.
81. Grigg M.E., Suzuki Y. Sexual recombination and clonal evolution of virulence in Toxoplasma. Microbes Infect. 2003, 5:685-690.
82. Grigg M.E., Bonnefoy S., Hehl A.B., Suzuki Y., Boothroyd J.C. Success and virulence in Toxoplasma as the result of sexual recombination between two distinct ancestries. Science 2001, 294:161-165.
83. Grigg M.E., Ganatra J., Boothroyd J.C., Margolis T.P. Unusual abundance of atypical strains asso-ciated with human ocular toxoplasmosis. J. Infect. Dis. 2001, 184:633-639.
84. Guo Z.G., Johnson A.M. Genetic characteri-zation of Toxoplasma gondii strains by random amplified polymorphic DNA polymerase chain reac-tion. Parasitology 1995, 111:127-132.
85. Guo Z.G., Gross U., Johnson A.M. Toxoplasma gondii virulence markers identified by random amplified polymorphic DNA polymerase chain reaction. Parasitol. Res. 1997, 83:458-463.
86. Høgdall E., Vuust J., Lind P., Petersen E. Characterisation of Toxoplasma gondii isolates using polymerase chain reaction (PCR) and restriction frag-ment length polymorphism (RFLP) of the non-coding To gondii (TGR) -gene sequences. Intl J. Parasitol. 2000, 30:853-858.
87. Honoré S., Couvelard A., Garin Y.J.F., et al. Géno-typage des souches de Toxoplasma gondii chez des patients immunodéprimés. Pathol. Biol. 2000, 48:541-547.
88. Howe D.K., Sibley L.D. Toxoplasma gondii: analysis of different laboratory stocks of the RH strain reveals genetic heterogeneity. Exp. Parasitol. 1994, 78:242-245.
89. Howe D.K., Sibley L.D. Toxoplasma gondii comprises three clonal lineages: correlation of para-site genotype with human disease. J. Infect. Dis. 1995, 172:1561-1566.
90. Howe D.K., Summers B.C., Sibley L.D. Acute virulence in mice is associated with markers on chro-mosome VIII in Toxoplasma gondii. Infect. Immun. 1996, 64:5193-5198.
91. Howe D.K., Honoré S., Derouin F., Sibley L.D. Determination of genotypes of Toxoplasma gondii strains isolated from patients with toxoplas-mosis. J. Clin. Microbiol. 1997, 35:1411-1414.
92. Hutchison W.M., Dunachie J.F., Siim J.C., Work K. Coccidian-like nature of Toxoplasma gondii. Br.Med. J. 1970, 1:142-144.
93. Khan A., Taylor S., Su C., et al. Composite genome map and recombination parameters derived from three archetypal lineages of Toxoplasma gondii. Nucleic Acids Res. 2005, 33:2980-2992.
94. Khan A., Su C., German M., Storch G.A., Clifford D.B., Sibley L.D. Genotyping of Toxoplasma gondii strains from immunocompromised patients reveals high prevalence of type I strains. J. Clin. Microbiol. 2005, 43:5881-5887.
95. Kong J.T., Grigg M.E., Uyetake L., Parmley S., Boothroyd J.C. Serotyping of Toxoplasma gondii infections in humans using synthetic peptides. J. Infect. Dis. 2003, 187:1484-1495.
96. Lehmann T., Blackston C.R., Parmley S.F., Remington J.S., Dubey J.P. Strain typing of Toxoplasma gondii: comparison of antigen-coding and housekeeping genes. J. Parasitol. 2000, 86:960-971.
97. Lehmann T., Graham D.H., Dahl E., et al. Transmission dynamics of Toxoplasma gondii on a pig farm. Infect. Genet. Evol. 2003, 3:135-141.
98. Lehmann T., Graham D.H., Dahl E.R., Bahia-Oliveira L.M.G., Gennari S.M., Dubey J.P. Variation in the structure of Toxoplasma gondii and the roles of selfing, drift, and epistatic selection in maintaining linkage disequilibria. Infect. Genet. Evol. 2004, 4:107-114.
99. Lin A., Shin E.H., Kim T.Y., Park J.H., Guk S.M., Chai J.Y. Genetic characteristics of the Korean isolate KI-1 of Toxoplasma gondii. Korean J. Parasitol. 2005, 43:27-32.
100. Lindsay D.S., Collins M.V., Mitchell S.M., et al. Survival of Toxoplasma gondii oocysts in Eastern oysters. (Crassostrea virginica) .J. Parasitol. 2004, 90:1054-1057.
101. Literák I., Rychlík I., Svobodová V., Pospíšil Z. Restriction fragment length polymorphism and virulence of Czech Toxoplasma gondii strains. Intl J. Parasitol. 1998, 28:1367-1374.
102. Mack D.G., Johnson J.J., Roberts F., et al. HLA-class II genes modify outcome of Toxoplasma gondii infection. Intl J. Parasitol. 1999, 29:1351-1358.
103. Mallon M., MacLeod A., Wastling J., Smith H., Reilly B., Tait A. Population structures and the role of genetic exchange in the zoonotic pathogen. Cryptosporidium parvum. J. Mol. Evol. 2003, 56:407-417.
104. Manger I.D., Hehl A., Parmley S., et al. Expressed sequence tag analysis of the bradyzoite stage of Toxoplasma gondii: identification of developmen-tally regulated genes. Infect. Immun. 1998, 66:1632-1637.
105. Marshall P.A., Hughes J.M., Williams R.H., Smith J.E., Murphy R.G., Hide G. Detection of high levels of congenital transmission of Toxoplasma gondii in natural urban populations of. Mus domesti-cus. Parasitology 2004, 128:39-42.
106. Meisel R., Stachelhaus S., Mévélec M.N., Reichmann G., Dubremetz J.F., Fischer H.G. Identification of two alleles in the GRA4 locus of Toxoplasma gondii determining a differential epitope which allows discrimination of type I versus type II a. Mol. Biochem. Parasitol. 1996, 81:259-263.
107. Messina M., Kim S., Sibley L.D. A family of dispersed DNA elements that contain GAA repeats in Toxoplasma gondii. Mol. Biochem. Parasitol. 1996, 81:247-252.
108. Miles M.A., Lanham S.M., de Souza A.A., Povoa M. Further enzymic characters of Trypanosoma cruzi and their evaluation for strain identification. Trans. R. Soc. Trop. Med. Hyg. 1980, 74:221-237.
109. Miller M.A., Gardner I.A., Kreuder C., et al. Coastal freshwater runoff is a risk factor for Toxoplasma gondii infection of southern sea otters. (Enhydra lutris nereis) . Intl J. Parasitol. 2002, 32:997-1006.
110. Miller M.A., Grigg M.E., Kreuder C., et al. An unusual genotype of Toxoplasma gondii is common in California sea otters (Enhydra lutris nereis) and is a cause of mortality. Intl J. Parasitol. 2004, 34:275-284.
111. Mondragon R., Howe D.K., Dubey J.P., Sibley L.D. Genotypic analysis of Toxoplasma gondii isolates from pigs. J. Parasitol. 1998, 84:639-641.
112. Montoya A., Miro G., Jimenez S., et al. Genotypic characterization of Toxoplasma gondii isolates from stray, farm and household cats in Spain. Abstract 239, MEEGID VII 2004.
113. Morley E.K., Williams R.H., Hughes J.M., et al. Significant familial differences in the frequency of abortion and Toxoplasma gondii infection within a flock of Charollais sheep. Parasitology 2005, 131:181-185.
114. Nguyen T.D., Bigaignon G., Markine-Goriaynoff D., et al. Virulent Toxoplasma gondii strain RH promotes T-cell-independent overproduction of proinflammatory cytokines IL12 and gamma-inter-feron. J. Med. Microbiol. 2003, 52:869-876.
115. Owen M.R., Trees A.J. Genotyping of Toxoplasma gondii associated with abortion in sheep. J. Parasitol. 1999, 85:382-384.
116. Parmley S.F., Gross U., Sucharczuk A., Windeck T., Sgarlato G.D., Remington J.S. Two alleles of the gene encoding surface antigen P22in 25 strains of Toxoplasma gondii. J. Parasitol. 1994, 80:293-301.
117. Rinder H., Thomschke A., Dardé M.L., Löscher T. Specific DNA polymorphisms discriminate between virulence and non-virulence to mice in nine Toxoplasma gondii strains. Mol. Biochem. Parasitol. 1995, 69:123-126.
118. Robben P.M., Mordue D.G., Truscott S.M., Takeda K., Akira S., Sibley L.D. Production of IL-12 by macrophages infected with Toxoplasma gondii depends on the parasite genotype. J. Immunol. 2004, 172:3686-3694.
119. Saeij J.P.J., Boyle J.P., Boothroyd J.C. Differences among the three major strains of Toxoplasma gondii and their specific interactions with the infected host. Trends Parasitol. 2005, 21:476-481.
120. Saeij J.P.J., Boyle J.P., Grigg M.E., Arrizabalaga G., Boothroyd J.C. Bioluminescence imaging of Toxoplasma gondii infection in living mice reveals dramatic differences between strains. Infect. Immun. 2005, 73:695-702.
121. Sargeaunt P.G., Williams J.E. Electrophoretic isoenzyme patterns of the pathogenic and non-path-ogenic intestinal amoebae of man. Trans. R. Soc. Trop. Med. Hyg. 1979, 73:225-227.
122. Sibley L.D. Recent origins among ancient para-sites. Vet. Parasitol. 2003, 115:185-198.
123. Sibley L.D., Boothroyd J.C. Virulent strains of Toxoplasma gondii comprise a single clonal lineage. Nature 1992, 359:82-85.
124. Sibley L.D., LeBlanc A.J., Pfefferkorn E.R., Boothroyd J.C. Generation of a restriction fragment length polymorphism linkage map for Toxoplasma gondii. Genetics 1992, 132:1003-1015.
125. Soete M., Fortier B., Camus D., Dubremetz J.F. Toxoplasma gondii: kinetics of bradyzoite-tachyzoite interconversion in vitro. Exp. Parasitol. 1993, 76:259-264.
126. Sreekumar C., Graham D.H., Dahl E., et al. Genotyping of Toxoplasma gondii isolates from chickens from India. Vet. Parasitol. 2003, 118:187-194.
127. Sreekumar C., Hill D.E., Miska K.B., et al. Genotyping and detection of multiple infections of Toxoplasma gondii using pyrosequencing. Intl J. Parasitol. 2005, 35:991-999.
128. Su C., Evans D., Cole R.H., Kissinger J.C., Ajioka J.W., Sibley L.D. Recent expansion of Toxoplasma through enhanced oral transmission. Science 2003, 299:414-416.
129. Suzuki Y., Wong S.Y., Grumet F.C., et al. Evidence for genetic regulation of susceptibility to toxoplasmic encephalitis in AIDS patients. J. Infect. Dis. 1996, 173:265-268.
130. Terry R.S., Smith J.E., Duncanson P., Hide G. MGE-PCR: a novel approach to the analysis of Toxoplasma gondii strain differentiation using mobile genetic elements. Intl J. Parasitol. 2001, 31:155-161.
131. Tibayrenc M. Entamoeba, Giardia and Toxoplasma: clones or cryptic species?. Parasitol. Today 1993, 9:102-105.
132. Tibayrenc M. Genetic epidemiology of parasitic protozoa and other infectious agents: the need for an integrated approach. Intl J. Parasitol. 1998, 28:85-104.
133. Tibayrenc M., Ayala F.J. The clonal theory of parasitic protozoa: 12 years on. Trends Parasitol. 2002, 18:405-410.
134. Tibayrenc M., Kjellberg F., Ayala F.J. A clonal theory of parasitic protozoa: the population struc- tures of Entamoeba, Giardia, Leishmania, Naegleria, Plasmodium, Trichomonas, and Trypanosoma and medical and taxonomical consequences. Proc. Natl Acad. Sci. USA 87, 2414-2418. Erratum in: Proc. Natl Acad. Sci. USA 87 1990, 8185.
135. Tibayrenc M., Kjellberg F., Arnaud J., et al. Are eukaryotic microorganisms clonal or sexual? A popu-lation genetics vantage. Proc. Natl Acad. Sci. USA 1991, 88:5129-5133.
136. Tinti M., Possenti A., Cherchi S., Barca S., Spano F. Analysis of the SAG5 locus reveals a distinct genomic organisation in virulent and avirulent strains of Toxoplasma gondii. Intl J. Parasitol. 2003, 33:1605-1616.
137. Vallochi A.L., Muccioli C., Martins M.C., Silveira C., Belfort R., Rizzo L.V. The genotype of Toxoplasma gondii strains causing ocular toxoplas-mosis in humans in Brazil. Am. J. Ophthalmol. 2005, 139:350-351.
138. Villena I., Marle M., Dardé M.L., Pinon J.M., Aubert D. Toxoplasma strain type and human disease: risk of bias during parasite isolation?. Trends Parasitol. 2004, 20:160-162.
139. Williams R.H., Morley E.K., Hughes J.M., et al. High levels of congenital transmission of Toxoplasma gondii in longitudinal and cross-sectional studies on sheep farms provides evidence of vertical transmis- ovine hosts. Parasitology 2005, 130:301-307.
140. Windeck T., Gross U. Toxoplasma gondii strain-specific transcript levels of SAG1 and their association with virulence. Parasitol. Res. 1996, 82:715-719.
141. Zenner L., Foulet A., Caudrelier Y., et al. Infection with Toxoplasma gondii RH and Prugniaud strains in mice, rats and nude rats: kinetics of infection in blood and tissues related to pathology in acut chronic infection. Pathol. Res. Pract. 1999, 195:475-485.