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Volumn 52, Issue 10, 2003, Pages 869-876

Virulent Toxoplasma gondii strain RH promotes T-cell-independent overproduction of proinflammatory cytokines IL12 and γ-interferon

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; CYTOKINE; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 4; TUMOR NECROSIS FACTOR ALPHA;

EID: 0142029555     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.04860-0     Document Type: Article
Times cited : (39)

References (44)
  • 2
    • 0035111755 scopus 로고    scopus 로고
    • Interleukin-12 promotes pathologic liver changes and death in mice coinfected with Schistosoma mansoni and Toxoplasma gondii
    • Araujo, M. I., Bliss, S. K., Suzuki, Y., Alcaraz, A., Denkers, E. Y. & Pearce, E. J. (2001). Interleukin-12 promotes pathologic liver changes and death in mice coinfected with Schistosoma mansoni and Toxoplasma gondii. Infect immun 69, 1454-1462.
    • (2001) Infect Immun , vol.69 , pp. 1454-1462
    • Araujo, M.I.1    Bliss, S.K.2    Suzuki, Y.3    Alcaraz, A.4    Denkers, E.Y.5    Pearce, E.J.6
  • 3
    • 0000236316 scopus 로고
    • Congenital transmission of toxoplasmosis through successive generations of mice
    • Beverley, J. K. A. (1959). Congenital transmission of toxoplasmosis through successive generations of mice. Nature 183, 1348-1350.
    • (1959) Nature , vol.183 , pp. 1348-1350
    • Beverley, J.K.A.1
  • 4
    • 0027936640 scopus 로고
    • Temporal differences in the expression of mRNA for IL-10 and IFN-γ in the brains and spleens of C57BL/10 mice infected with Toxoplasma gondii
    • Burke, J. M., Roberts, C. W., Hunter, C. A., Murray, M. & Alexander, J. (1994). Temporal differences in the expression of mRNA for IL-10 and IFN-γ in the brains and spleens of C57BL/10 mice infected with Toxoplasma gondii. Parasite Immunol 16, 305-314.
    • (1994) Parasite Immunol , vol.16 , pp. 305-314
    • Burke, J.M.1    Roberts, C.W.2    Hunter, C.A.3    Murray, M.4    Alexander, J.5
  • 5
    • 0022569771 scopus 로고
    • Rheumatoid factor production in 129/sv mice: Involvement of an intestinal infectious agent
    • Coutelier, J.-P., van der Logt, J. T. M., Heessen, F. W. A., Warnier, G. & Van Snick, J. (1986a). Rheumatoid factor production in 129/sv mice: involvement of an intestinal infectious agent. J Immunol 137, 337-340.
    • (1986) J Immunol , vol.137 , pp. 337-340
    • Coutelier, J.-P.1    Van Der Logt, J.T.M.2    Heessen, F.W.A.3    Warnier, G.4    Van Snick, J.5
  • 6
    • 0022450267 scopus 로고
    • The murine antibody response to lactate dehydrogenase-elevating virus
    • Coutelier, J.-P., Van Roost, E., Lambotte, P. & Van Snick, J. (1986b). The murine antibody response to lactate dehydrogenase-elevating virus. J Gen Virol 67, 1099-1108.
    • (1986) J Gen Virol , vol.67 , pp. 1099-1108
    • Coutelier, J.-P.1    Van Roost, E.2    Lambotte, P.3    Van Snick, J.4
  • 7
    • 0028878655 scopus 로고
    • Interleukin-12 gene expression after viral infection in the mouse
    • Coutelier, J.-P., Van Broeck, J. & Wolf, S. F. (1995). Interleukin-12 gene expression after viral infection in the mouse. J Virol 69, 1955-1958.
    • (1995) J Virol , vol.69 , pp. 1955-1958
    • Coutelier, J.-P.1    Van Broeck, J.2    Wolf, S.F.3
  • 8
    • 0034235462 scopus 로고    scopus 로고
    • Lethal granuloma disintegration in mycobacteria-infected TNFRp55-/- Mice is dependent on T cells and IL-12
    • Ehlers, S., Kutsch, S., Ehlers, E. M., Benini, J. & Pfeffer, K. (2000). Lethal granuloma disintegration in mycobacteria-infected TNFRp55-/- mice is dependent on T cells and IL-12. J Immunol 165, 483-492.
    • (2000) J Immunol , vol.165 , pp. 483-492
    • Ehlers, S.1    Kutsch, S.2    Ehlers, E.M.3    Benini, J.4    Pfeffer, K.5
  • 9
    • 0024408824 scopus 로고
    • Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones
    • Fiorentino, B. F., Bond, M. W. & Mosmann, T. R. (1989). Two types of mouse T helper cell. IV. Th2 clones secrete a factor that inhibits cytokine production by Th1 clones. J Exp Med 170, 2081-2095.
    • (1989) J Exp Med , vol.170 , pp. 2081-2095
    • Fiorentino, B.F.1    Bond, M.W.2    Mosmann, T.R.3
  • 10
    • 0023726937 scopus 로고
    • Anti-proliferative effect of IFN-γ in immune regulation. I. IFN-γ inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones
    • Gajewski, T. F. & Fitch, F. W. (1988). Anti-proliferative effect of IFN-γ in immune regulation. I. IFN-γ inhibits the proliferation of Th2 but not Th1 murine helper T lymphocyte clones. J Immunol 140, 4245-4252.
    • (1988) J Immunol , vol.140 , pp. 4245-4252
    • Gajewski, T.F.1    Fitch, F.W.2
  • 11
    • 0026021838 scopus 로고
    • + T lymphocytes in IFN-γ production and protective immunity induced by an attenuated Toxo-plasma gondii vaccine
    • + T lymphocytes in IFN-γ production and protective immunity induced by an attenuated Toxo-plasma gondii vaccine. J Immunol 146, 286-292.
    • (1991) J Immunol , vol.146 , pp. 286-292
    • Gazzinelli, R.T.1    Hakim, F.T.2    Hieny, S.3    Shearer, G.M.4    Sher, A.5
  • 12
  • 13
    • 0027264849 scopus 로고
    • Interleukin-12 is required for the T-cell-independent induction of interferon-γ by an intracellular parasite and induces resistance in T-cell-deficient hosts
    • Gazzinelli, R. T., Hieny, S., Wynn, T., Wolf, S. & Sher, A. (1993a). Interleukin-12 is required for the T-cell-independent induction of interferon-γ by an intracellular parasite and induces resistance in T-cell-deficient hosts. Proc Natl Acad Sci USA 90, 6115-6119.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 6115-6119
    • Gazzinelli, R.T.1    Hieny, S.2    Wynn, T.3    Wolf, S.4    Sher, A.5
  • 14
    • 0027208743 scopus 로고
    • Acute cerebral toxoplasmosis is induced by in vivo neutralization of TNF-α and correlates with the down-regulated expression of inducible nitric oxide synthase and other markers of macrophage activation
    • Gazzinelli, R. T., Eltoum, I., Wynn, T. A. & Sher, A. (1993b). Acute cerebral toxoplasmosis is induced by in vivo neutralization of TNF-α and correlates with the down-regulated expression of inducible nitric oxide synthase and other markers of macrophage activation. J Immunol 151, 3672-3681.
    • (1993) J Immunol , vol.151 , pp. 3672-3681
    • Gazzinelli, R.T.1    Eltoum, I.2    Wynn, T.A.3    Sher, A.4
  • 15
    • 0027939611 scopus 로고
    • Parasite-induced IL-12 stimulates early IFN-γ synthesis and resistance during acute infection with Toxoplasma gondii
    • Gazzinelli, R. T., Wysocka, M., Hayashi, S., Denkers, E. Y., Hieny, S., Caspar, P., Trinchieri, G. & Sher, A. (1994). Parasite-induced IL-12 stimulates early IFN-γ synthesis and resistance during acute infection with Toxoplasma gondii. J Immunol 153, 2533-2543.
    • (1994) J Immunol , vol.153 , pp. 2533-2543
    • Gazzinelli, R.T.1    Wysocka, M.2    Hayashi, S.3    Denkers, E.Y.4    Hieny, S.5    Caspar, P.6    Trinchieri, G.7    Sher, A.8
  • 17
    • 0023189866 scopus 로고
    • Tumor necrosis factor (cachetin) as an essential mediator in murine cerebral malaria
    • Grau, G. E., Farjardo, L. F., Piguet, P. F., Allet, B., Lambert, P. H. & Vassalli, P. (1987). Tumor necrosis factor (cachetin) as an essential mediator in murine cerebral malaria. Science 237, 1210-1212.
    • (1987) Science , vol.237 , pp. 1210-1212
    • Grau, G.E.1    Farjardo, L.F.2    Piguet, P.F.3    Allet, B.4    Lambert, P.H.5    Vassalli, P.6
  • 18
    • 0028085437 scopus 로고
    • Interleukin-12 is produced in vivo during endotoxemia and stimulates synthesis of gamma Interferon
    • Heinzel, F. P., Rerko, R. M., Ling, P., Hakimi, J. & Schoenhaut, D. S. (1994). Interleukin-12 is produced in vivo during endotoxemia and stimulates synthesis of gamma Interferon. Infect Immun 62, 4244-4249.
    • (1994) Infect Immun , vol.62 , pp. 4244-4249
    • Heinzel, F.P.1    Rerko, R.M.2    Ling, P.3    Hakimi, J.4    Schoenhaut, D.S.5
  • 19
    • 0025365576 scopus 로고
    • Interferon gamma, a mediator of lethal lipopolysaccharide-induced Schwartzman-like shock reactions in mice
    • Heremans, H., Van Damme, J., Dillen, C., Dijkmans, R. & Billiau, A. (1990). Interferon gamma, a mediator of lethal lipopolysaccharide-induced Schwartzman-like shock reactions in mice. J Exp Med 171, 1853-1869.
    • (1990) J Exp Med , vol.171 , pp. 1853-1869
    • Heremans, H.1    Van Damme, J.2    Dillen, C.3    Dijkmans, R.4    Billiau, A.5
  • 20
    • 0031230377 scopus 로고    scopus 로고
    • Heat shock protein 65 induced by γδ T cells prevents apoptosis of macrophages and contributes to host defense in mice infected with Toxoplasma gondii
    • Hisaeda, H., Sakai, T., Ishikawa, H., Maekawa, Y., Yasutomo, K., Good, R. A. & Himeno, K. (1997). Heat shock protein 65 induced by γδ T cells prevents apoptosis of macrophages and contributes to host defense in mice infected with Toxoplasma gondii. J Immunol 159, 2375-2381.
    • (1997) J Immunol , vol.159 , pp. 2375-2381
    • Hisaeda, H.1    Sakai, T.2    Ishikawa, H.3    Maekawa, Y.4    Yasutomo, K.5    Good, R.A.6    Himeno, K.7
  • 21
    • 0030867026 scopus 로고    scopus 로고
    • Gamma interferon induces Fas-dependent apoptosis of Peyer's patch T cells in mice following peroral infection with Toxoplasma gondii
    • Liesenfeld, O., Kosek, J. C. & Suzuki, Y. (1997). Gamma interferon induces Fas-dependent apoptosis of Peyer's patch T cells in mice following peroral infection with Toxoplasma gondii. Infect Immun 65, 4682-4689.
    • (1997) Infect Immun , vol.65 , pp. 4682-4689
    • Liesenfeld, O.1    Kosek, J.C.2    Suzuki, Y.3
  • 23
    • 0034802358 scopus 로고    scopus 로고
    • Distinct requirements for IL-6 in polyclonal and specific Ig production induced by microorganisms
    • Markine-Goriaynoff, D., Nguyen, T. D., Bigaignon, G., Van Snick, J. & Coutelier, J.-P. (2001). Distinct requirements for IL-6 in polyclonal and specific Ig production induced by microorganisms. Int Immunol 13, 1185-1192.
    • (2001) Int Immunol , vol.13 , pp. 1185-1192
    • Markine-Goriaynoff, D.1    Nguyen, T.D.2    Bigaignon, G.3    Van Snick, J.4    Coutelier, J.-P.5
  • 26
    • 0035887943 scopus 로고    scopus 로고
    • Acute toxoplasmosis leads to lethal overproduction of Th1 cytokines
    • Mordue, D. G., Monroy, F., La Regina, M., Dinarello, C. A. & Sibley, L. D. (2001). Acute toxoplasmosis leads to lethal overproduction of Th1 cytokines. J Immunol 167, 4574-4584.
    • (2001) J Immunol , vol.167 , pp. 4574-4584
    • Mordue, D.G.1    Monroy, F.2    La Regina, M.3    Dinarello, C.A.4    Sibley, L.D.5
  • 27
    • 0022640843 scopus 로고
    • Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
    • Mosmann, T. R., Cherwinski, H., Bond, M. W., Giedlin, M. A. & Coffman, R. L. (1986). Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 136, 2348-2357.
    • (1986) J Immunol , vol.136 , pp. 2348-2357
    • Mosmann, T.R.1    Cherwinski, H.2    Bond, M.W.3    Giedlin, M.A.4    Coffman, R.L.5
  • 28
    • 1842417179 scopus 로고    scopus 로고
    • Role of interleukin-10 in regulation of T-cell-dependent mechanisms of resistance to Toxoplasma gondii
    • Neyer, L. E., Grunig, G., Fort, M., Remington, J. S., Rennick, D. & Hunter, C. A. (1997). Role of interleukin-10 in regulation of T-cell-dependent mechanisms of resistance to Toxoplasma gondii. Infect Immun 65, 1675-1682.
    • (1997) Infect Immun , vol.65 , pp. 1675-1682
    • Neyer, L.E.1    Grunig, G.2    Fort, M.3    Remington, J.S.4    Rennick, D.5    Hunter, C.A.6
  • 29
    • 0020607440 scopus 로고
    • Comparative effects of cotrimoxazole (trimethoprim-sulphamethoxazole), pyrimethamine-sulphadiazine and spiramycin during avirulent infection with Toxo-plasma gondii (Beverley strain) in mice
    • Nguyen, B. T. & Stadtsbaeder, S. (1983). Comparative effects of cotrimoxazole (trimethoprim-sulphamethoxazole), pyrimethamine-sulphadiazine and spiramycin during avirulent infection with Toxo-plasma gondii (Beverley strain) in mice. Br J Pharmacol 79, 923-928.
    • (1983) Br J Pharmacol , vol.79 , pp. 923-928
    • Nguyen, B.T.1    Stadtsbaeder, S.2
  • 32
    • 0027982098 scopus 로고
    • Interleukin 12, interferon-γ, and tumour necrosis factor-a are the key cytokines of the generalized Schwartzman reaction
    • Ozmen, L., Pericin, M., Hakimi, J., Chizzonite, R. A., Wysocka, M., Trinchieri, G., Gately, M. & Garotta, G. (1994). Interleukin 12, interferon-γ, and tumour necrosis factor-a are the key cytokines of the generalized Schwartzman reaction. J Exp Med 180, 907-915.
    • (1994) J Exp Med , vol.180 , pp. 907-915
    • Ozmen, L.1    Pericin, M.2    Hakimi, J.3    Chizzonite, R.A.4    Wysocka, M.5    Trinchieri, G.6    Gately, M.7    Garotta, G.8
  • 33
    • 0026056142 scopus 로고
    • IFN-γ modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis
    • Scott, P. (1991). IFN-γ modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis. J Immunol 147, 3149-3155.
    • (1991) J Immunol , vol.147 , pp. 3149-3155
    • Scott, P.1
  • 34
    • 0024236111 scopus 로고
    • Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens
    • Scott, P., Natovitz, P., Coffman, R. L., Pearce, E. & Sher, A. (1988). Immunoregulation of cutaneous leishmaniasis. T cell lines that transfer protective immunity or exacerbation belong to different T helper subsets and respond to distinct parasite antigens. J Exp Med 168, 1675-1684.
    • (1988) J Exp Med , vol.168 , pp. 1675-1684
    • Scott, P.1    Natovitz, P.2    Coffman, R.L.3    Pearce, E.4    Sher, A.5
  • 35
    • 0027241272 scopus 로고
    • Toxoplasma gondii induces a T-independent IFN-γ response in natural killer cells that requires both adherent accessory cells and tumor necrosis factor-α
    • Sher, A., Oswald, I. P., Hieny, S. & Gazzinelli, R. T. (1993). Toxoplasma gondii induces a T-independent IFN-γ response in natural killer cells that requires both adherent accessory cells and tumor necrosis factor-α. J Immunol 150, 3982-3989.
    • (1993) J Immunol , vol.150 , pp. 3982-3989
    • Sher, A.1    Oswald, I.P.2    Hieny, S.3    Gazzinelli, R.T.4
  • 36
    • 0024438401 scopus 로고
    • Importance of endogenous IFN-γ for prevention of toxoplasmic encephalitis in mice
    • Suzuki, Y., Conley, F. K. & Remington, J. S. (1989). Importance of endogenous IFN-γ for prevention of toxoplasmic encephalitis in mice. J Immunol 143, 2045-2050.
    • (1989) J Immunol , vol.143 , pp. 2045-2050
    • Suzuki, Y.1    Conley, F.K.2    Remington, J.S.3
  • 38
    • 0034658617 scopus 로고    scopus 로고
    • IL-10 is required for prevention of necrosis in the small intestine and mortality in both genetically resistant BALB/c and susceptible C57BL/6 mice following peroral infection with Toxoplasma gondii
    • Suzuki, Y., Sher, A., Yap, G., Park, D., Neyer, L. E., Liesenfeld, O., Fort, M., Kang, H. & Gufwoli, E. (2000). IL-10 is required for prevention of necrosis in the small intestine and mortality in both genetically resistant BALB/c and susceptible C57BL/6 mice following peroral infection with Toxoplasma gondii. J Immunol 164, 5375-5382.
    • (2000) J Immunol , vol.164 , pp. 5375-5382
    • Suzuki, Y.1    Sher, A.2    Yap, G.3    Park, D.4    Neyer, L.E.5    Liesenfeld, O.6    Fort, M.7    Kang, H.8    Gufwoli, E.9
  • 39
    • 0029022765 scopus 로고
    • Protective effect of low doses of an anti-IL-4 monoclonal antibody in a murine model of acute toxoplasmosis
    • Villard, O., Candolfi, E., Despringre, J. L., Derouin, F., Marcellin, L., Viville, S. & Kien, T. (1995). Protective effect of low doses of an anti-IL-4 monoclonal antibody in a murine model of acute toxoplasmosis. Parasite Immunol 17, 233-236.
    • (1995) Parasite Immunol , vol.17 , pp. 233-236
    • Villard, O.1    Candolfi, E.2    Despringre, J.L.3    Derouin, F.4    Marcellin, L.5    Viville, S.6    Kien, T.7
  • 40
    • 0031029093 scopus 로고    scopus 로고
    • Innate immunity to Toxoplasma gondii is influenced by gender and is associated with differences in interleukin-12 and gamma interferon production
    • Walker, W., Roberts, C. W., Ferguson, D. J. P., Jebbari, H. & Alexander, J. (1997). Innate immunity to Toxoplasma gondii is influenced by gender and is associated with differences in interleukin-12 and gamma interferon production. Infect Immun 65, 1119-1121.
    • (1997) Infect Immun , vol.65 , pp. 1119-1121
    • Walker, W.1    Roberts, C.W.2    Ferguson, D.J.P.3    Jebbari, H.4    Alexander, J.5
  • 41
    • 0035731769 scopus 로고    scopus 로고
    • Interleukin-10 does not contribute to the pathogenesis of a virulent strain of Toxoplasma gondii
    • Wille, U., Villegas, E. N., Striepen, B., Roos, D. S. & Hunter, C. A. (2001). Interleukin-10 does not contribute to the pathogenesis of a virulent strain of Toxoplasma gondii. Parasite Immunol 23, 291-296.
    • (2001) Parasite Immunol , vol.23 , pp. 291-296
    • Wille, U.1    Villegas, E.N.2    Striepen, B.3    Roos, D.S.4    Hunter, C.A.5
  • 42
    • 0025875022 scopus 로고
    • Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells
    • Wolf, S. F., Temple, P. A., Kobayashi, M. & 14 other authors (1991). Cloning of cDNA for natural killer cell stimulatory factor, a heterodimeric cytokine with multiple biologic effects on T and natural killer cells. J Immunol 146, 3074-3081.
    • (1991) J Immunol , vol.146 , pp. 3074-3081
    • Wolf, S.F.1    Temple, P.A.2    Kobayashi, M.3
  • 43
    • 0028987562 scopus 로고
    • Interleukin-12 is required for interferon-γ production and lethality in lipopolysaccharide-induced shock in mice
    • Wysocka, M., Kubin, M., Vieira, L. Q., Ozmen, L., Garotta, G., Scott, P. & Trinchieri, G. (1995). Interleukin-12 is required for interferon-γ production and lethality in lipopolysaccharide-induced shock in mice. Eur J Immunol 25, 672-676.
    • (1995) Eur J Immunol , vol.25 , pp. 672-676
    • Wysocka, M.1    Kubin, M.2    Vieira, L.Q.3    Ozmen, L.4    Garotta, G.5    Scott, P.6    Trinchieri, G.7
  • 44
    • 0034662258 scopus 로고    scopus 로고
    • Cutting edge: IL-12 is required for the maintenance of IFN-γ production in T cells mediating chronic resistance to the intracellular pathogen, Toxoplasma gondii
    • Yap, G., Pesin, M. & Sher, A. (2000). Cutting edge: IL-12 is required for the maintenance of IFN-γ production in T cells mediating chronic resistance to the intracellular pathogen, Toxoplasma gondii. J Immunol 165, 628-631.
    • (2000) J Immunol , vol.165 , pp. 628-631
    • Yap, G.1    Pesin, M.2    Sher, A.3


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