Efficient array-based identification of novel cardiac genes through differentiation of mouse ESCs

PLoS ONE

Volumn 3, Issue 5, 2008, Pages

  Miller, Ronald A ^a   Christoforou, Nicolas ^a   Pevsner, Jonathan ^a,b   McCallion, Andrew S ^a   Gearhart, John D ^a  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b KENNEDY KRIEGER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

RECEPTOR ACTIVITY MODIFYING PROTEIN 2; RNA; TRANSCRIPTION FACTOR GATA 4; TRANSCRIPTION FACTOR NKX2.5;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL FATE; CELL FUNCTION; CELL SELECTION; CONTROLLED STUDY; EMBRYO; EMBRYO PATTERN FORMATION; EMBRYONIC STEM CELL; GENE EXPRESSION; GENE IDENTIFICATION; GENE SEQUENCE; GENETIC TRANSCRIPTION; HEART DEVELOPMENT; HEART FUNCTION; IN SITU HYBRIDIZATION; MICROARRAY ANALYSIS; MOUSE; NONHUMAN; PREDICTION; SEQUENCE ANALYSIS; ANIMAL; CELL SEPARATION; CYTOLOGY; DNA MICROARRAY; GENE EXPRESSION PROFILING; HEART MUSCLE; METABOLISM; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; CELL DIFFERENTIATION; CELL SEPARATION; EMBRYONIC STEM CELLS; GENE EXPRESSION PROFILING; IN SITU HYBRIDIZATION; MICE; MYOCARDIUM; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 48249139056     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0002176     Document Type: Article

References (26)

1. Harvey RP (2002) Patterning the vertebrate heart. Nat Rev Genet 3: 544-556.
2. Tam PP, Parameswaran M, Kinder SJ, Weinberger RP (1997) The allocation of epiblast cells to the embryonic heart and other mesodermal lineages: the role of ingression and tissue movement during gastrulation. Development 124: 1631-1642.
3. Kelly RG, Brown NA, Buckingham ME (2001) The arterial pole of the mouse heart forms from Fgf10-expressing cells in pharyngeal mesoderm. Dee Cell 1: 435-440.
4. Abu-Issa R, Waldo K, Kirby ML (2004) Heart fields: one, two or more? Dev Biol 272: 281-285.
5. Cai CL, Liang X, Shi Y, Chu PH, Pfaff SL, et al. (2003) Is11 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart. Dev Cell 5: 877-889.
6. Bodmer R (1993) The gene tinman is required for specification of the heart and visceral muscles in Drosophila. Development 118: 719-729.
7. Lyons I, Parsons LM, Hartley L, Li R, Andrews JE, et al. (1995) Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5. Genes Dee 9: 1654-1666.
8. Hescheler J, Fleischmann BK, Lentini S, Maltsev VA, Rohwedel J, et al. (1997) Embryonic stem cells: a model to study structural and functional properties in cardiomyogenesis, Cardiovasc Res 36: 149-162.
9. Boheler KR, Czyz J, Tweedie D, Yang HT, Anisimov SV, et al. (2002) Differentiation of pluripotent embryonic stem cells into cardiomyocytes. Circ Res 91: 189-201.
10. Keller G (2005) Embryonic stem cell differentiation: emergence of a new era in biology and medicine. Genes Dev 19: 1129-1155.
11. Christoforou N, Miller RA, Hill CM, Jie CC, McCallion AS, et al. (2008) Mouse. ES cell-derived cardiac precursor cells are multipotent and facilitate identification of novel cardiac genes. J Clin Invest.
12. Kattman SJ, Huber TL, Keller GM (2006) Multipotent flk-1+ cardiovascular progenitor cells give rise to the cardiomyocyte, endothelial, and vascular smooth muscle lineages. Dee Cell 11: 723-732.
13. Wu SM, Fujiwara, Y, Cibulsky SM, Clapham DE, Lien CL, et al. (2006) Developmental origin of a bipotential myocardial and smooth muscle cell precursor in the mammalian heart. Cell 127: 1137-1150.
14. Moretti A, Caron L, Nakano A, Lam JT, Bernshausen A, et al. (2006) Multipotent embryonic is11+ progenitor cells lead to cardiac, smooth muscle, and endothelial cell diversification. Cell 127: 1151-1165.
15. Lien CL, Wu C, Mercer B, Webb R, Richardson JA, et al. (1999) Control of early cardiac-specific transcription of Nkx2-5 by a GATA-dependent enhancer. Development 126: 75-84.
16. Maltsev VA, Rohwedel J, Hescheler J, Wobus AM (1993) Embryonic stem cells differentiate in vitro into candiomyocytes representing sinusnodal, atrial and ventricular cell types. Mech Dev 44: 41-50.
17. Takahashi T, Lord B, Schulze PC, Fryer RM, Sarang SS, et al. (2003) Ascorbic acid enhances differentiation of embryonic stem cells into cardiac myocytes. Circulation 107: 1912-1916.
18. Irizarry RA, Hobbs B, Collin F, Beazer-Barclay YD, Antonellis KJ, et al. (2003) Exploration, normalization, and summaries of high density oligonucleotide array probe level data. Biostatistics 4: 249-264.
19. Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, et al. (2000) Gene ontology: tool for the unification of biology. The Gene Ontology Consortium. Nat Genet 25: 25-29.
20. Eppig JT, Blake JA, Bult CJ, Kadin JA, Richardson JE (2007) The mouse genome database NGD): new features facilitating a model system. Nucleic Acids Res 35: D630-637.
21. Stennard FA, Costa MW, Elliott DA, Rankin S, Haast SJ, et al. (2003) Cardiac T-box factor Tbx20 directly interacts with Nkx2-5, GATA4, and GATA5 in regulation of gene expression in the developing heart. Dev Biol 262: 206-224.
22. Wilkinson DG, Nieto MA (1993) Detection of messenger RNA by in situ hybridization to tissue sections and whole mounts. Methods Enzymol 225: 361-373.
23. Masino AM, Gallardo TD, Wilcox CA, Olson EN, Williams RS, et al. (2004) Transcriptional regulation of cardiac progenitor cell populations. Circ Res 95: 389-397.
24. Thomas T, Yamagishi H, Overbeck PA, Olson EN, Srivastava D (1998) The bHLH factors, dHAND and eHAND, specify pulmonary and systemic cardiac ventricles independent of left-right sidedness. Dee Biol 196: 228-236.
25. Kasahara H, Bartunkova S, Schinke M, Tanaka M, Izumo S (1998) Cardiac and extracardiac expression of Csx/Nkx2.5 homeodomain protein. Circ Res 82: 936-946.
26. Gibson-Brown JJ, Agulnik SI, Silver LM, Niswander L, Papaioannou VE (1998) Involvement of T-box genes Tbx2-Tbx5 in vertebrate limb specification and development. Development 125: 2499-2509.