메뉴 건너뛰기




Volumn 29, Issue 2 SUPPL., 2008, Pages

Folate and vitamin B12, metabolism: Overview and interaction with riboflavin, vitamin B6, and polymorphisms

Author keywords

Folate; Homocysteine; Megaloblastic anemia; Methionine synthase; MTHFR; Neural tube defects; One carbon metabolism; Polymorphisms; Riboflavin; Vitamin B12

Indexed keywords

AMINO ACID; ANEMIA; CONFERENCE PROCEEDING; METABOLISM; NUTRITION; POLYMORPHISM; VITAMIN;

EID: 48249138116     PISSN: 03795721     EISSN: None     Source Type: Journal    
DOI: 10.1177/15648265080292s103     Document Type: Conference Paper
Times cited : (114)

References (64)
  • 1
    • 24744432278 scopus 로고    scopus 로고
    • Folic acid
    • Rucker RB, Suttie JW, McCormack DB, Machlin LJ, eds, 3rd ed. New York: Marcel Dekker
    • Brody T, Shane B. Folic acid. In: Rucker RB, Suttie JW, McCormack DB, Machlin LJ, eds. Handbook of the vitamins, 3rd ed. New York: Marcel Dekker, 2001:427-62.
    • (2001) Handbook of the vitamins , pp. 427-462
    • Brody, T.1    Shane, B.2
  • 2
    • 85086611485 scopus 로고    scopus 로고
    • 6. In: Stipanuk MH, ed. Biochemical, physiological, molecular aspects of human nutrition, 2nd ed. New York: Saunders, 2006:693-732.
    • 6. In: Stipanuk MH, ed. Biochemical, physiological, molecular aspects of human nutrition, 2nd ed. New York: Saunders, 2006:693-732.
  • 3
    • 0034703861 scopus 로고    scopus 로고
    • Glutamate carboxypeptidase II: A polymorphism associated with lower levels of serum folate and hyperhomocysteinemia
    • Devlin AM, Ling EH, Peerson JM, Fernando S, Clarke R, Smith AD, Halsted CH. Glutamate carboxypeptidase II: A polymorphism associated with lower levels of serum folate and hyperhomocysteinemia. Hum Mol Genet 2000;9:2837-44.
    • (2000) Hum Mol Genet , vol.9 , pp. 2837-2844
    • Devlin, A.M.1    Ling, E.H.2    Peerson, J.M.3    Fernando, S.4    Clarke, R.5    Smith, A.D.6    Halsted, C.H.7
  • 5
    • 0003296460 scopus 로고    scopus 로고
    • Folate
    • Food and Nutrition Board, Institute of Medicine, Washington, DC: National Academy Press
    • 12, pantothenic acid, biotin and choline. Washington, DC: National Academy Press, 2000:196-305.
    • (2000) 12, pantothenic acid, biotin and choline , pp. 196-305
  • 6
    • 0027982786 scopus 로고
    • A novel cDNA restores reduced folate carrier activity and methotrexate sensitivity to transport deficient cells
    • Dixon KH, Lanpher BC, Chiu J, Kelley K, Cowan KH. A novel cDNA restores reduced folate carrier activity and methotrexate sensitivity to transport deficient cells. J Biol Chem 1994;269:17-20.
    • (1994) J Biol Chem , vol.269 , pp. 17-20
    • Dixon, K.H.1    Lanpher, B.C.2    Chiu, J.3    Kelley, K.4    Cowan, K.H.5
  • 7
    • 0027503126 scopus 로고
    • Internalization and intracellular transport of folate-binding protein in rat kidney proximal tubule
    • Birn H, Selhub J, Christensen EI. Internalization and intracellular transport of folate-binding protein in rat kidney proximal tubule. Am J Physiol 1993;264:C302-10.
    • (1993) Am J Physiol , vol.264
    • Birn, H.1    Selhub, J.2    Christensen, E.I.3
  • 8
    • 0034711259 scopus 로고    scopus 로고
    • Retrovirally mediated complementation of the glyB phenotype. Cloning of a human gene encoding the carrier for entry of folates into mitochondria
    • Titus SA, Moran RG. Retrovirally mediated complementation of the glyB phenotype. Cloning of a human gene encoding the carrier for entry of folates into mitochondria. J Biol Chem 2000;47:36811-7.
    • (2000) J Biol Chem , vol.47 , pp. 36811-36817
    • Titus, S.A.1    Moran, R.G.2
  • 9
    • 15844381051 scopus 로고    scopus 로고
    • Purification and properties of human cytosolic folylpoly-γ-glutamate synthetase and organization, localization, and differential splicing of its gene
    • Chen L, Qi H, Korenberg J, Garrow TA, Choi YJ, Shane B. Purification and properties of human cytosolic folylpoly-γ-glutamate synthetase and organization, localization, and differential splicing of its gene. J Biol Chem 1996;271:13077-87.
    • (1996) J Biol Chem , vol.271 , pp. 13077-13087
    • Chen, L.1    Qi, H.2    Korenberg, J.3    Garrow, T.A.4    Choi, Y.J.5    Shane, B.6
  • 10
    • 0031031304 scopus 로고    scopus 로고
    • Stites TE, Bailey LB, Scott KC, Toth JP, Fisher WP, Gregory JF 3rd. Kinetic modeling of folate metabolism through use of chronic administration of deuterium-labeled folic acid in men. Am J Clin Nutr 1997; 65:53-60.
    • Stites TE, Bailey LB, Scott KC, Toth JP, Fisher WP, Gregory JF 3rd. Kinetic modeling of folate metabolism through use of chronic administration of deuterium-labeled folic acid in men. Am J Clin Nutr 1997; 65:53-60.
  • 12
    • 0026356764 scopus 로고
    • Bacterially synthesized folate in rat large intestine is incorporated into host tissue folyl polyglutamates
    • Rong N, Selhub J, Goldin BR, Rosenberg IH. Bacterially synthesized folate in rat large intestine is incorporated into host tissue folyl polyglutamates. J Nutr 1991; 121:1955-9.
    • (1991) J Nutr , vol.121 , pp. 1955-1959
    • Rong, N.1    Selhub, J.2    Goldin, B.R.3    Rosenberg, I.H.4
  • 13
    • 0027223085 scopus 로고
    • Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization
    • Garrow TA, Brenner AA, Whitehead VM, Chen XN, Duncan RG, Korenberg JR, Shane B. Cloning of human cDNAs encoding mitochondrial and cytosolic serine hydroxymethyltransferases and chromosomal localization. J Biol Chem 1993;268:11910-6.
    • (1993) J Biol Chem , vol.268 , pp. 11910-11916
    • Garrow, T.A.1    Brenner, A.A.2    Whitehead, V.M.3    Chen, X.N.4    Duncan, R.G.5    Korenberg, J.R.6    Shane, B.7
  • 14
    • 0023789244 scopus 로고
    • In vitro evidence for the involvement of mitochondrial folate metabolism in the supply of cytoplasmic one-carbon units
    • Barlowe CK, Appling DR. In vitro evidence for the involvement of mitochondrial folate metabolism in the supply of cytoplasmic one-carbon units. Biofactors 1988;1:171-6.
    • (1988) Biofactors , vol.1 , pp. 171-176
    • Barlowe, C.K.1    Appling, D.R.2
  • 15
    • 0033646360 scopus 로고    scopus 로고
    • 3H] serine allows in vivo kinetic measurement of serine turnover, homocysteine remethylation, and transsulfuration processes in human one-carbon metabolism
    • 3H] serine allows in vivo kinetic measurement of serine turnover, homocysteine remethylation, and transsulfuration processes in human one-carbon metabolism. Am J Clin Nutr 2000;72:1535-41.
    • (2000) Am J Clin Nutr , vol.72 , pp. 1535-1541
    • Gregory, J.F.1    Cuskelly, G.R.2    Shane, B.3    Toth, J.P.4    Baumgartner, T.G.5    Stacpoole, P.W.6
  • 16
    • 0031035739 scopus 로고    scopus 로고
    • Molecular cloning, characterization, and regulation of the human mitochondrial serine hydroxymethyltransferase gene
    • Stover PJ, Chen LH, Suh JR, Stover DM, Keyomarsi K, Shane B. Molecular cloning, characterization, and regulation of the human mitochondrial serine hydroxymethyltransferase gene. J Biol Chem 1997;272:1842-8.
    • (1997) J Biol Chem , vol.272 , pp. 1842-1848
    • Stover, P.J.1    Chen, L.H.2    Suh, J.R.3    Stover, D.M.4    Keyomarsi, K.5    Shane, B.6
  • 20
    • 0016722112 scopus 로고
    • Labile methyl balances for normal humans on various dietary regimens
    • Mudd SH, Poole JR. Labile methyl balances for normal humans on various dietary regimens. Metabolism 1975;24:721-35.
    • (1975) Metabolism , vol.24 , pp. 721-735
    • Mudd, S.H.1    Poole, J.R.2
  • 22
    • 0033551352 scopus 로고    scopus 로고
    • The effect of folic acid fortification on plasma folate and total homocysteine concentrations
    • Jacques PF, Selhub J, Bostom AG, Wilson PW, Rosenberg IH. The effect of folic acid fortification on plasma folate and total homocysteine concentrations. N Engl J Med 1999;340:1449-54.
    • (1999) N Engl J Med , vol.340 , pp. 1449-1454
    • Jacques, P.F.1    Selhub, J.2    Bostom, A.G.3    Wilson, P.W.4    Rosenberg, I.H.5
  • 23
    • 17044382257 scopus 로고    scopus 로고
    • 12
    • Food and Nutrition Board, Institute of Medicine, Washington, DC: National Academy Press
    • 12, pantothenic acid, biotin and choline. Washington, DC: National Academy Press, 2000:306-56.
    • (2000) 12, pantothenic acid, biotin and choline , pp. 306-356
  • 24
  • 25
    • 0035085657 scopus 로고    scopus 로고
    • Transfer of cobalamin from intrinsic factor to transcobalamin II
    • Brada N, Gordon MM, Wen J, Alpers DH. Transfer of cobalamin from intrinsic factor to transcobalamin II. J Nutr Biochem 2001;12:200-6.
    • (2001) J Nutr Biochem , vol.12 , pp. 200-206
    • Brada, N.1    Gordon, M.M.2    Wen, J.3    Alpers, D.H.4
  • 33
    • 14644401110 scopus 로고    scopus 로고
    • Characterization of a succinyl-CoA radical-cob(II)alamin spin triplet intermediate in the reaction catalyzed by adenosylcobalamin-dependent methylmalonyl-CoA mutase
    • Mansoorabadi SO, Padmakumar R, Fazliddinova N, Vlasie M, Banerjee R, Reed GH. Characterization of a succinyl-CoA radical-cob(II)alamin spin triplet intermediate in the reaction catalyzed by adenosylcobalamin-dependent methylmalonyl-CoA mutase. Biochemistry 2005;44:3153-8.
    • (2005) Biochemistry , vol.44 , pp. 3153-3158
    • Mansoorabadi, S.O.1    Padmakumar, R.2    Fazliddinova, N.3    Vlasie, M.4    Banerjee, R.5    Reed, G.H.6
  • 34
    • 0031749452 scopus 로고    scopus 로고
    • Genetic defects of folate and cobalamin metabolism
    • Fowler B. Genetic defects of folate and cobalamin metabolism. Eur J Pediatr 1998;157(suppl 2):S60-6.
    • (1998) Eur J Pediatr , vol.157 , Issue.SUPPL. 2
    • Fowler, B.1
  • 37
    • 0034090534 scopus 로고    scopus 로고
    • Current concepts in cobalamin deficiency
    • Carmel R. Current concepts in cobalamin deficiency. Annu Rev Med 2000;51:357-75.
    • (2000) Annu Rev Med , vol.51 , pp. 357-375
    • Carmel, R.1
  • 40
    • 0028295618 scopus 로고
    • Helicobacter pylori infection and food-cobalamin malabsorption
    • Carmel R, Perez-Perez GI, Blaser MJ. Helicobacter pylori infection and food-cobalamin malabsorption. Dig Dis Sci 1994;39:309-14.
    • (1994) Dig Dis Sci , vol.39 , pp. 309-314
    • Carmel, R.1    Perez-Perez, G.I.2    Blaser, M.J.3
  • 41
    • 0026735941 scopus 로고
    • Cobalamin deficiency and the pathogenesis of nervous system disease
    • Metz J. Cobalamin deficiency and the pathogenesis of nervous system disease. Annu Rev Nutr 1992; 12:59-79.
    • (1992) Annu Rev Nutr , vol.12 , pp. 59-79
    • Metz, J.1
  • 43
    • 0028905178 scopus 로고
    • Seven novel mutations in the methylenetetrahydrofolate reductase gene and genotype/phenotype correlations in severe methylenetetrahydrofolate reductase deficiency
    • Goyette P, Frosst P, Rosenblatt DS, Rozen R. Seven novel mutations in the methylenetetrahydrofolate reductase gene and genotype/phenotype correlations in severe methylenetetrahydrofolate reductase deficiency. Am J Hum Genet 1995;56:1052-9.
    • (1995) Am J Hum Genet , vol.56 , pp. 1052-1059
    • Goyette, P.1    Frosst, P.2    Rosenblatt, D.S.3    Rozen, R.4
  • 44
    • 0032941095 scopus 로고    scopus 로고
    • Cobalamin and folate deficiency: Acquired and hereditary disorders in children
    • Rosenblatt DS, Whitehead VM. Cobalamin and folate deficiency: acquired and hereditary disorders in children. Semin Hematol 1999;36:19-34.
    • (1999) Semin Hematol , vol.36 , pp. 19-34
    • Rosenblatt, D.S.1    Whitehead, V.M.2
  • 47
    • 0037216404 scopus 로고    scopus 로고
    • Effect of food fortification on folic acid intake in the United States
    • Quinlivan EP, Gregory JF III. Effect of food fortification on folic acid intake in the United States. Am J Clin Nutr 2003;77:221-5.
    • (2003) Am J Clin Nutr , vol.77 , pp. 221-225
    • Quinlivan, E.P.1    Gregory III, J.F.2
  • 48
    • 0035919139 scopus 로고    scopus 로고
    • Impact of folic acid fortification of the US food supply on the occurrence of neural tube defects
    • Honein MA, Paulozzi LJ, Mathews TJ, Erickson JD, Wong L-YC. Impact of folic acid fortification of the US food supply on the occurrence of neural tube defects. JAMA 2001;285:2981-6.
    • (2001) JAMA , vol.285 , pp. 2981-2986
    • Honein, M.A.1    Paulozzi, L.J.2    Mathews, T.J.3    Erickson, J.D.4    Wong, L.-Y.C.5
  • 50
    • 0036057549 scopus 로고    scopus 로고
    • Incidence of open neural tube defects in Nova Scotia after folic acid fortification
    • Persad VL, Van den Hof MC, Dube JM, Zimmer P. Incidence of open neural tube defects in Nova Scotia after folic acid fortification. Can Med Assoc J 2002;167:241-5.
    • (2002) Can Med Assoc J , vol.167 , pp. 241-245
    • Persad, V.L.1    Van den Hof, M.C.2    Dube, J.M.3    Zimmer, P.4
  • 51
    • 0043093697 scopus 로고    scopus 로고
    • Transposable elements: Targets for early nutritional effects on epigenetic gene regulation
    • Waterland RA, Jirtle RL. Transposable elements: targets for early nutritional effects on epigenetic gene regulation. Mol Cell Biol 2003;23:5293-5300.
    • (2003) Mol Cell Biol , vol.23 , pp. 5293-5300
    • Waterland, R.A.1    Jirtle, R.L.2
  • 55
    • 0032573077 scopus 로고    scopus 로고
    • A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells
    • Bagley PJ, Selhub J. A common mutation in the methylenetetrahydrofolate reductase gene is associated with an accumulation of formylated tetrahydrofolates in red blood cells. PNAS 1998;95:13217-20.
    • (1998) PNAS , vol.95 , pp. 13217-13220
    • Bagley, P.J.1    Selhub, J.2
  • 56
    • 0032895522 scopus 로고    scopus 로고
    • The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia
    • Guenther BD, Sheppard CA, Tran P, Rozen R, Matthews RG, Ludwig ML. The structure and properties of methylenetetrahydrofolate reductase from Escherichia coli suggest how folate ameliorates human hyperhomocysteinemia. Nat Struct Biol 1999;6:359-65.
    • (1999) Nat Struct Biol , vol.6 , pp. 359-365
    • Guenther, B.D.1    Sheppard, C.A.2    Tran, P.3    Rozen, R.4    Matthews, R.G.5    Ludwig, M.L.6
  • 57
    • 0036171590 scopus 로고    scopus 로고
    • The relationship between riboflavin and plasma total homocysteine in the Framingham offspring cohort is influenced by folate status and the C677T transition in the methylenetetrahydrofolate reductase gene
    • Jacques PF, Kalmbach R, Bagley PJ, Russo GT, Rogers G, Wilson PWF, Rosenberg IH, Selhub J. The relationship between riboflavin and plasma total homocysteine in the Framingham offspring cohort is influenced by folate status and the C677T transition in the methylenetetrahydrofolate reductase gene. J Nutr 2002;132:283-8.
    • (2002) J Nutr , vol.132 , pp. 283-288
    • Jacques, P.F.1    Kalmbach, R.2    Bagley, P.J.3    Russo, G.T.4    Rogers, G.5    Wilson, P.W.F.6    Rosenberg, I.H.7    Selhub, J.8
  • 60
    • 0033607241 scopus 로고    scopus 로고
    • Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults
    • Skibola CF, Smith MT, Kane E, Roman E, Rollinson S, Cartwright R, Morgan G. Polymorphisms in the methylenetetrahydrofolate reductase gene are associated with susceptibility to acute leukemia in adults. Proc Natl Acad Sci USA 1999;96:12810-5.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 12810-12815
    • Skibola, C.F.1    Smith, M.T.2    Kane, E.3    Roman, E.4    Rollinson, S.5    Cartwright, R.6    Morgan, G.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.