-
1
-
-
9544245792
-
Intragraft IL-15 transcripts are increased in human renal allograft rejection
-
Pavlakis, M., Strehlau, J., Lipman, M., Shapiro, M., Maslinski, W. and Strom, T B. 1996. Intragraft IL-15 transcripts are increased in human renal allograft rejection. Transplantation 62:543.
-
(1996)
Transplantation
, vol.62
, pp. 543
-
-
Pavlakis, M.1
Strehlau, J.2
Lipman, M.3
Shapiro, M.4
Maslinski, W.5
Strom, T.B.6
-
2
-
-
0031884806
-
Interleukin 15: A proinflammatory role in rheumatoid arthritis synovitis
-
McInnes, I. B. and Liew, F. Y. 1998. Interleukin 15: A proinflammatory role in rheumatoid arthritis synovitis. Immunol. Today 19:75.
-
(1998)
Immunol. Today
, vol.19
, pp. 75
-
-
McInnes, I.B.1
Liew, F.Y.2
-
3
-
-
8944235345
-
The role of IL-15, IL-2, and their receptors in the development of T cell alveolitis in pulmonary sarcoidosis
-
Agostini, C., Trentin, L., Facco, M. et al. 1996. The role of IL-15, IL-2, and their receptors in the development of T cell alveolitis in pulmonary sarcoidosis. J. Immunol 157:910.
-
(1996)
J. Immunol
, vol.157
, pp. 910
-
-
Agostini, C.1
Trentin, L.2
Facco, M.3
-
4
-
-
0029833667
-
Increased number of IL-15-expresing cells in active ulcerative colitis
-
Kirman, I. and Nielsen, O. H. 1996. Increased number of IL-15-expresing cells in active ulcerative colitis. Am. J. Gastroenterol. 91:1789.
-
(1996)
Am. J. Gastroenterol
, vol.91
, pp. 1789
-
-
Kirman, I.1
Nielsen, O.H.2
-
5
-
-
1942453326
-
Homeostatic expansion of T cells during immune insufficiency generates autoimmunity
-
King, C., Ilic, A., Koelsch, K. and Sarvetnick, N. 2004. Homeostatic expansion of T cells during immune insufficiency generates autoimmunity. Cell 117:265.
-
(2004)
Cell
, vol.117
, pp. 265
-
-
King, C.1
Ilic, A.2
Koelsch, K.3
Sarvetnick, N.4
-
6
-
-
14044262247
-
-
Vollmer, T. L., Liu, R., Price, M., Rhodes, S., La. Cava, A. and Shi, F. D. 2005. Differential effects of IL-21 during initiation and progression of autoimmunity against neuroantigen. J. Immunol. 174:2696.
-
Vollmer, T. L., Liu, R., Price, M., Rhodes, S., La. Cava, A. and Shi, F. D. 2005. Differential effects of IL-21 during initiation and progression of autoimmunity against neuroantigen. J. Immunol. 174:2696.
-
-
-
-
7
-
-
0034597789
-
Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function
-
Parrish-Novak, J., Dillon, S. R., Nelson, A. et al. 2000. Interleukin 21 and its receptor are involved in NK cell expansion and regulation of lymphocyte function. Nature 408:57.
-
(2000)
Nature
, vol.408
, pp. 57
-
-
Parrish-Novak, J.1
Dillon, S.R.2
Nelson, A.3
-
8
-
-
0037514399
-
IL-21 in synergy with IL-15 or IL-18 enhances IFN-γ production in human NK and T cells
-
Strengell, M., Matikainen, S., Siren, J. et al. 2003. IL-21 in synergy with IL-15 or IL-18 enhances IFN-γ production in human NK and T cells. J. Immunol. 170:5464.
-
(2003)
J. Immunol
, vol.170
, pp. 5464
-
-
Strengell, M.1
Matikainen, S.2
Siren, J.3
-
9
-
-
0037159687
-
A critical role for IL-21 in regulating immunoglobulin production
-
Ozaki, K., Spolski, R., Feng, C. G. et al. 2002. A critical role for IL-21 in regulating immunoglobulin production. Science 298: 1630.
-
(2002)
Science
, vol.298
, pp. 1630
-
-
Ozaki, K.1
Spolski, R.2
Feng, C.G.3
-
10
-
-
0037037544
-
IL-21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon γ-producing Th1 cells
-
Wurster, A., Rodgers, V L., Satoskar, A. R. et al. 2002. IL-21 is a T helper (Th) cell 2 cytokine that specifically inhibits the differentiation of naive Th cells into interferon γ-producing Th1 cells. J. Exp. Med. 196:969.
-
(2002)
J. Exp. Med
, vol.196
, pp. 969
-
-
Wurster, A.1
Rodgers, V.L.2
Satoskar, A.R.3
-
11
-
-
34848855805
-
Human CD4+ central and effector memory T cells produce IL-21: Effect on cytokine-driven proliferation of CD4+ T cell subsets
-
Onoda, T., Rahman, M., Nara, H. et al. 2007. Human CD4+ central and effector memory T cells produce IL-21: Effect on cytokine-driven proliferation of CD4+ T cell subsets. Int. Immunol. 19:1191.
-
(2007)
Int. Immunol
, vol.19
, pp. 1191
-
-
Onoda, T.1
Rahman, M.2
Nara, H.3
-
12
-
-
0034633734
-
Cloning of a type I cytokine receptor most related to the IL-2 receptor β chain
-
Ozaki, K., Kikly, K., Michalovich, D., Young, P. R. and Leonard, W. J. 2000. Cloning of a type I cytokine receptor most related to the IL-2 receptor β chain. Proc. Natl Acad. Sci. USA 97:11439.
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 11439
-
-
Ozaki, K.1
Kikly, K.2
Michalovich, D.3
Young, P.R.4
Leonard, W.J.5
-
13
-
-
9644295710
-
Cytokines and immunodeficiency diseases: Critical roles of the γc-dependent cytokines interleukins 2,4,7,9,15, and 21, and their signaling pathways
-
Kovanen, P. and Leonard, W. J. 2004. Cytokines and immunodeficiency diseases: Critical roles of the γc-dependent cytokines interleukins 2,4,7,9,15, and 21, and their signaling pathways. Immunol. Rev. 202:67.
-
(2004)
Immunol. Rev
, vol.202
, pp. 67
-
-
Kovanen, P.1
Leonard, W.J.2
-
14
-
-
0030890933
-
Transduction of IL-2 antiapoptotic and proliferative signals via Akt protein kinase
-
Ahmed, N. N., Grimes, H. L., Bellacosa, A., Chan, T. O. and Tsichlis, P. N. 1997. Transduction of IL-2 antiapoptotic and proliferative signals via Akt protein kinase. Proc. Natl Acad. Sci. USA 94:3627.
-
(1997)
Proc. Natl Acad. Sci. USA
, vol.94
, pp. 3627
-
-
Ahmed, N.N.1
Grimes, H.L.2
Bellacosa, A.3
Chan, T.O.4
Tsichlis, P.N.5
-
15
-
-
0842278642
-
IL-21 induces the functional maturation of murine NK cells
-
Brady, J., Hayakawa, Y., Smyth, M. J. and Nutt, S. L. 2004. IL-21 induces the functional maturation of murine NK cells. J. Immunol. 172:2048.
-
(2004)
J. Immunol
, vol.172
, pp. 2048
-
-
Brady, J.1
Hayakawa, Y.2
Smyth, M.J.3
Nutt, S.L.4
-
16
-
-
31144479124
-
IL-21 down-regulates NKG2D/DAP10 expression on human NK and CD8+ T cells
-
Burgess, S. J., Marusina, A. I., Pathmanathan, I., Borrego, F. and Coligan, J. E. 2006. IL-21 down-regulates NKG2D/DAP10 expression on human NK and CD8+ T cells. J. Immunol. 176:1490.
-
(2006)
J. Immunol
, vol.176
, pp. 1490
-
-
Burgess, S.J.1
Marusina, A.I.2
Pathmanathan, I.3
Borrego, F.4
Coligan, J.E.5
-
17
-
-
34547232503
-
IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells
-
Korn, T, Bettelli, E., Gao, W. et al. 2007. IL-21 initiates an alternative pathway to induce proinflammatory T(H)17 cells. Nature 448:484.
-
(2007)
Nature
, vol.448
, pp. 484
-
-
Korn, T.1
Bettelli, E.2
Gao, W.3
-
18
-
-
0036852893
-
IL-21 and the IL-21 receptor: Novel effectors of NK and T cell responses
-
Parrish-Novak, J., Foster, D. C., Holly, R. D. and Clegg, C. H. 2002. IL-21 and the IL-21 receptor: Novel effectors of NK and T cell responses. J. Leukoc. Biol. 72:856.
-
(2002)
J. Leukoc. Biol
, vol.72
, pp. 856
-
-
Parrish-Novak, J.1
Foster, D.C.2
Holly, R.D.3
Clegg, C.H.4
-
19
-
-
0028855894
-
IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes
-
Lacraz, S., Nicod, L. P., Chicheportiche, R., Welgus, H. G. and Dayer, J. M. 1995, IL-10 inhibits metalloproteinase and stimulates TIMP-1 production in human mononuclear phagocytes. J. Clin. Invest. 96:2304.
-
(1995)
J. Clin. Invest
, vol.96
, pp. 2304
-
-
Lacraz, S.1
Nicod, L.P.2
Chicheportiche, R.3
Welgus, H.G.4
Dayer, J.M.5
-
20
-
-
0029944290
-
Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia
-
Garcia-Zepeda, E. A., Rothenberg, M. E., Ownbey, R. T., Celestin, J., Leder, P. and Luster, A. D. 1996. Human eotaxin is a specific chemoattractant for eosinophil cells and provides a new mechanism to explain tissue eosinophilia. Nat. Med. 2:449.
-
(1996)
Nat. Med
, vol.2
, pp. 449
-
-
Garcia-Zepeda, E.A.1
Rothenberg, M.E.2
Ownbey, R.T.3
Celestin, J.4
Leder, P.5
Luster, A.D.6
-
21
-
-
0028262128
-
Determination of lymphocyte division by flow cytometry (CFSE)
-
Lyons, A. B. and Parish, C. R. 1994. Determination of lymphocyte division by flow cytometry (CFSE). J. Immunol. Methods 171:131.
-
(1994)
J. Immunol. Methods
, vol.171
, pp. 131
-
-
Lyons, A.B.1
Parish, C.R.2
-
22
-
-
0035132135
-
IL-15 and IL-2: A matter of life and death for T cells in vivo
-
Li, X. C., Demirci, G., Ferrari-Lacraz, S. et al. 2001. IL-15 and IL-2: A matter of life and death for T cells in vivo. Nat. Med. 7:114.
-
(2001)
Nat. Med
, vol.7
, pp. 114
-
-
Li, X.C.1
Demirci, G.2
Ferrari-Lacraz, S.3
-
23
-
-
14044273004
-
The production of IL-1Ra in IFN-β-stimulated human monocytes depends on the activation of phosphatidylinositol 3-kinase but not of STAT1
-
Molnarfi, N., Hyka-Nouspikel, N., Gruaz, L., Dayer, J. M. and Burger, D. 2005. The production of IL-1Ra in IFN-β-stimulated human monocytes depends on the activation of phosphatidylinositol 3-kinase but not of STAT1. J. Immunol. 174:2974.
-
(2005)
J. Immunol
, vol.174
, pp. 2974
-
-
Molnarfi, N.1
Hyka-Nouspikel, N.2
Gruaz, L.3
Dayer, J.M.4
Burger, D.5
-
24
-
-
19944434230
-
Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function
-
Zeng, R., Spolski, R., Finkelstein, S. E. et al. 2005. Synergy of IL-21 and IL-15 in regulating CD8+ T cell expansion and function. J. Exp. Med. 201:139.
-
(2005)
J. Exp. Med
, vol.201
, pp. 139
-
-
Zeng, R.1
Spolski, R.2
Finkelstein, S.E.3
-
25
-
-
0344129022
-
CD45 isoform phenotypes of human T cells: CD4(+)CD45RA(-)RO(+) memory T cells re-acquire CD45RA without losing CD45RO
-
Arlettaz, L., Barbey, C., Dumont-Girard, F. et al. 1999. CD45 isoform phenotypes of human T cells: CD4(+)CD45RA(-)RO(+) memory T cells re-acquire CD45RA without losing CD45RO. Eur. J. Immunol. 29:3987.
-
(1999)
Eur. J. Immunol
, vol.29
, pp. 3987
-
-
Arlettaz, L.1
Barbey, C.2
Dumont-Girard, F.3
-
26
-
-
0033554726
-
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
-
Sallusto, F., Lenig, D., Foerster, R., Lipp, M. and Lanzavecchia, A. 1999. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature 401:708.
-
(1999)
Nature
, vol.401
, pp. 708
-
-
Sallusto, F.1
Lenig, D.2
Foerster, R.3
Lipp, M.4
Lanzavecchia, A.5
-
27
-
-
0037080219
-
IL-2 and related cytokines can promote T cell survival by activating AKT
-
Kelly, E., Won, A., Refaeli, Y. and Van Parijs, L. 2002. IL-2 and related cytokines can promote T cell survival by activating AKT. J. Immunol. 168:597.
-
(2002)
J. Immunol
, vol.168
, pp. 597
-
-
Kelly, E.1
Won, A.2
Refaeli, Y.3
Van Parijs, L.4
-
28
-
-
0037855829
-
Antiapoptotic signaling by the IL-2 receptor reveals a function for cytoplasmic tyrosine residues within the common gamma (γc) receptor subunit
-
Lindemann, M. J., Benczik, M. and Gaffen, S. L. 2003. Antiapoptotic signaling by the IL-2 receptor reveals a function for cytoplasmic tyrosine residues within the common gamma (γc) receptor subunit. J. Biol. Chem. 278:10239.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 10239
-
-
Lindemann, M.J.1
Benczik, M.2
Gaffen, S.L.3
-
29
-
-
85117737804
-
-
Establishment of the CD4+ T-cell pool in healthy children and untreated children infected with HIV-1, 04:3513
-
Hazenberg, M. D., Otto, S. A., van Rossum, A. M. et al. 2004. Establishment of the CD4+ T-cell pool in healthy children and untreated children infected with HIV-1. Blood 04:3513.
-
(2004)
Blood
-
-
Hazenberg, M.D.1
Otto, S.A.2
van Rossum, A.M.3
-
30
-
-
0036672918
-
Maintaining the norm: T-cell homeostasis
-
Jameson, S. C. 2002. Maintaining the norm: T-cell homeostasis. Nat. Rev. Immunol. 2:547.
-
(2002)
Nat. Rev. Immunol
, vol.2
, pp. 547
-
-
Jameson, S.C.1
-
31
-
-
2542565699
-
IL-21 is a T-helper cytokine that regulates humoral immunity and cell-mediated anti-tumor responses
-
Sivakumar, P., Foster, D. C. and Clegg, C. H. 2004. IL-21 is a T-helper cytokine that regulates humoral immunity and cell-mediated anti-tumor responses. Immunology 112:177.
-
(2004)
Immunology
, vol.112
, pp. 177
-
-
Sivakumar, P.1
Foster, D.C.2
Clegg, C.H.3
-
32
-
-
2542595794
-
IL-21 enhances and sustains CD8+ T cell responses to achieve durable tumor immunity: Comparative evaluation of IL-2, IL-15 and IL-21
-
Moroz, A., Eppolito, C., Li, Q., Tao, J., Clegg, C. H. and Shrikant, P. A. 2004, IL-21 enhances and sustains CD8+ T cell responses to achieve durable tumor immunity: Comparative evaluation of IL-2, IL-15 and IL-21. J. Immunol. 173:900.
-
(2004)
J. Immunol
, vol.173
, pp. 900
-
-
Moroz, A.1
Eppolito, C.2
Li, Q.3
Tao, J.4
Clegg, C.H.5
Shrikant, P.A.6
-
33
-
-
0037111241
-
Proliferation requirements of cytomegalovirus-specitic, effector-type human CD8+ T cells
-
van Leeuwen, E. M.G. L., Baars, P. A., Remmerswaal, E. B., ten Berge, I. J. and van Lier, R. A. 2002. Proliferation requirements of cytomegalovirus-specitic, effector-type human CD8+ T cells. J. Immunol. 169:5838.
-
(2002)
J. Immunol
, vol.169
, pp. 5838
-
-
van Leeuwen, E.M.G.L.1
Baars, P.A.2
Remmerswaal, E.B.3
ten Berge, I.J.4
van Lier, R.A.5
-
34
-
-
37749035317
-
-
de Rham, C.. Ferrari-Lacraz, S, Jendly, S., Schneiter, G., Dayer, J. M. and Villard, J. 2007. The proinflammatory cytokines; IL-2, IL-15 and IL-21 modulate the repertoire of mature human NK cell receptors. Arthritis Res. Ther. 9:R125.
-
de Rham, C.. Ferrari-Lacraz, S,, Jendly, S., Schneiter, G., Dayer, J. M. and Villard, J. 2007. The proinflammatory cytokines; IL-2, IL-15 and IL-21 modulate the repertoire of mature human NK cell receptors. Arthritis Res. Ther. 9:R125.
-
-
-
-
35
-
-
23244444668
-
IL-21 sustains CD28 expression on IL-15-activated human naive CD8+ T cells
-
Alves, N. L., Arosa, F. A. and van Lier, R. A. 2005. IL-21 sustains CD28 expression on IL-15-activated human naive CD8+ T cells. J. Immunol. 175:755.
-
(2005)
J. Immunol
, vol.175
, pp. 755
-
-
Alves, N.L.1
Arosa, F.A.2
van Lier, R.A.3
-
36
-
-
0032212138
-
The IL-2 receptor promotes proliferation, bcl-2 and bcl-x induction, but not cell viability through the adapter molecule Shc
-
Lord, J. D., McIntosh, B. C., Greenberg, P. D. and Nelson, B. H. 1998. The IL-2 receptor promotes proliferation, bcl-2 and bcl-x induction, but not cell viability through the adapter molecule Shc. J. Immunol. 161:4627.
-
(1998)
J. Immunol
, vol.161
, pp. 4627
-
-
Lord, J.D.1
McIntosh, B.C.2
Greenberg, P.D.3
Nelson, B.H.4
-
37
-
-
6344269331
-
-
Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6, 173.5361
-
Ozaki, K., Spolski, R., Ettinger, R. et al. 2004. Regulation of B cell differentiation and plasma cell generation by IL-21, a novel inducer of Blimp-1 and Bcl-6. J. Immunol. 173.5361.
-
(2004)
J. Immunol
-
-
Ozaki, K.1
Spolski, R.2
Ettinger, R.3
-
38
-
-
0037446642
-
IL-21 induces apoptosis of resting and activated primary B cells
-
Mehta, D., Wurster, A. L., Whitters, M. J., Young, D. A., Collins, M. and Grusby, M. J. 2003. IL-21 induces apoptosis of resting and activated primary B cells. J. Immunol. 170:4111.
-
(2003)
J. Immunol
, vol.170
, pp. 4111
-
-
Mehta, D.1
Wurster, A.L.2
Whitters, M.J.3
Young, D.A.4
Collins, M.5
Grusby, M.J.6
-
39
-
-
34548390650
-
IL-21 promotes T lymphocyte survival by activating the phosphatidylinositol-3 kinase signaling cascade
-
Ostiguy, V., Allard, E. L., Marquis, M,, Leignadier, J. and Labrecque, N. 2007. IL-21 promotes T lymphocyte survival by activating the phosphatidylinositol-3 kinase signaling cascade. J. Leukoc. Biol. 82:645.
-
(2007)
J. Leukoc. Biol
, vol.82
, pp. 645
-
-
Ostiguy, V.1
Allard, E.L.2
Marquis, M.3
Leignadier, J.4
Labrecque, N.5
|