Transcriptional feedback and definition of the circadian pacemaker in Drosophila and animals

Cold Spring Harbor Symposia on Quantitative Biology

Volumn 72, Issue , 2007, Pages 75-83

  Rosbash, M ^a   Bradley, S ^a   Kadener, S ^a   Li, Y ^a   Luo, W ^a   Menet, J S ^a   Nagoshi, E ^a   Palm, K ^a   Schoer, R ^a   Shang, Y ^a   Tang, C H A ^a  

^a BRANDEIS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PHOSPHOTRANSFERASE; RECOMBINANT DNA; NUCLEAR PROTEIN; PERIOD PROTEIN, INSECT;

ANIMAL; CIRCADIAN RHYTHM; CLONING; DROSOPHILA; ENZYME SUBSTRATE; FEEDBACK SYSTEM; GENE SEQUENCE; GENETIC IDENTIFICATION; GENETIC TRANSCRIPTION; MUTANT; NONHUMAN; PROTEIN PROCESSING; BIOLOGICAL MODEL; GENE; GENETICS; PHYSIOLOGY; REVIEW;

ANIMALS; CIRCADIAN RHYTHM; DROSOPHILA; FEEDBACK, BIOCHEMICAL; GENES, INSECT; MODELS, BIOLOGICAL; NUCLEAR PROTEINS; TRANSCRIPTION, GENETIC;

EID: 48249119511     PISSN: 00917451     EISSN: None     Source Type: Book Series    
DOI: 10.1101/sqb.2007.72.062     Document Type: Conference Paper

References (67)

1. Allada R., Kadener S., Nandakumar N., and Rosbash M. 2003. A recessive mutant of Drosophila Clock reveals a role in circadian rhythm amplitude. EMBO J. 22: 3367.
2. Allada R., White N., So W., Hall J., and Rosbash M. 1998. A mutant Drosophila homolog of mammalian Clock disrupts circadian rhythms and transcription of period and timeless. Cell 93: 791.
3. Antoch M.P., Song E.-J., Chang A.-M., Vitaterna M.H., Zhao Y., Wilsbacher L.D., Sangoram A.M., King D.P., Pinto L.H., and Takahashi J.S. 1997. Functional identification of the mouse circadian Clock gene by transgenic BAC rescue. Cell 89: 655.
4. Aronson B.D., Johnson K.A., Loros J.J., and Dunlap J.C. 1994. Negative feedback defining a circadian clock: Autoregulation of the clock gene frequency. Science 263: 1578.
5. Bargiello T.A. and Young M.W. 1984. Molecular genetics of a biological clock in Drosophila. Proc. Natl. Acad. Sci. 81: 2142.
6. Bargiello T.A., Jackson F.R., and Young M.W. 1984. Restoration of circadian behavioural rhythms by gene transfer in Drosophila. Nature 312: 752.
7. Baylies M.K., Bargiello T.A., Jackson F.R., and Young M.W. 1987. Changes in abundance or structure of the per gene product can alter periodicity of the Drosophila clock. Nature 326: 390.
8. Brown S.A., Ripperger J., Kadener S., Fleury-Olela F., Vilbois F., Rosbash M., and Schibler U. 2005. PERIOD1-associated proteins modulate the negative limb of the mammalian circadian oscillator. Science 308: 693.
9. Colot H.V., Hall J.C., and Rosbash M. 1988. Interspecific comparison of the period gene of Drosophila reveals large blocks of non-conserved coding DNA. EMBO J. 7: 3929.
10. Crews S.T., Thomas J.B., and Goodman C.S. 1988. The Drosophila single-minded gene encodes a nuclear protein with sequence similarity to the per gene product. Cell 52: 143.
11. Darlington T.K., Wager-Smith K., Ceriani M.F., Staknis D., Gekakis N., Steeves T.D., Weitz C.J., Takahashi J.S., and Kay S.A. 1998. Closing the circadian loop: CLOCK-induced transcription of its own inhibitors per and tim. Science 280: 1599.
12. Dunlap J.C. 1999. Molecular bases for circadian clocks. Cell 96: 271.
13. Edery I., Zwiebel L.J., Dembinska M.E., and Rosbash M. 1994. Temporal phosphorylation of the Drosophila period protein. Proc. Natl. Acad. Sci. 91: 2260.
14. Gallego M., Eide E.J., Woolf M.F., Virshup D.M., and Forger D.B. 2006. An opposite role for tau in circadian rhythms revealed by mathematical modeling. Proc. Natl. Acad. Sci. 103: 10618.
15. Gekakis N., Saez L., Delahaye-Brown A.-M., Myers M.P., Sehgal A., Young M.W., and Weitz C.J. 1995. Isolation of timeless by PER protein interaction: Defective interaction between timeless protein and long-period mutant PERL. Science 270: 811.
16. Hamblen-Coyle M.J., Wheeler D.A., Rutila J.E., Rosbash M., and Hall J.C. 1992. Behavior of period-altered circadian rhythm mutants of Drosophila in light: Dark cycles (Diptera: Drosophilidae). J. Insect Behav. 5: 417.
17. Hardin P.E., Hall J.C., and Rosbash M. 1990. Feedback of the Drosophila period gene product on circadian cycling of its messenger RNA levels. Nature 343: 536.
18. -. 1992. Circadian oscillations in period gene mRNA levels are transcriptionally regulated. Proc. Natl. Acad. Sci. 89: 11711.
19. Honma S., Kawamoto T., Takagi Y., Fujimoto K., Sato F., Noshiro M., Kato Y., and Honma K. 2002. Dec1 and Dec2 are regulators of the mammalian molecular clock. Nature 419: 841.
20. Houl J.H., Yu W., Dudek S.M., and Hardin P.E. 2006. Drosophila CLOCK is constitutively expressed in circadian oscillator and non-oscillator cells. J. Biol. Rhythms 21: 93.
21. Huang Z.J., Edery I., and Rosbash M. 1993. PAS is a dimerization domain common to Drosophila Period and several transcription factors. Nature 364: 259.
22. Jackson F.R., Bargiello T.A., Yun S.-H., and Young M.W. 1986. Product of per locus of Drosophila shares homology with proteoglycans. Nature 320: 185.
23. Kadener S., Stoleru D., McDonald M., Nawathean P., and Rosbash M. 2007. Clockwork Orange is a transcriptional repressor and a new Drosophila circadian pacemaker component. Genes Dev. 21: 1675.
24. Kaneko M., Park J., Cheng Y., Hardin P., and Hall J. 2000. Disruption of synaptic transmission or clock-gene-product oscillations in circadian pacemaker cells of Drosophila cause abnormal behavioral rhythms. J. Neurobiol. 43: 207.
25. King D.P., Zhao Y., Sangoram A.M., Wilsbacher L.D., Tanaka M., Antoch M.P., Steeves T.D., Vitaterna M.H., Kornhauser J.M., Lowrey P.L., Turek F.W., and Takahashi J.S. 1997. Positional cloning of the mouse circadian clock gene. Cell 89: 641.
26. Kloss B., Price J.L., Saez L., Blau J., Rothenfluh-Hilfiker A., Wesley C.S., and Young M.W. 1998. The Drosophila clock gene double-time encodes a protein closely related to human casein kinase Iε. Cell 94: 97.
27. Konopka R.J. and Benzer S. 1971. Clock mutants of Drosophila melanogaster. Proc. Natl. Acad. Sci. 68: 2112.
28. Lim C., Chung B.Y., Pitman J.L., McGill J.J., Pradhan S., Lee J., Keegan K.P., Choe J., and Allada R. 2007. clockwork orange encodes a transcriptional repressor important for circadianclock amplitude in Drosophila. Curr. Biol. 17: 1082.
29. Lin J.M., Kilman V.L., Keegan K., Paddock B., Emery-Le M., Rosbash M., and Allada R. 2002. A role for casein kinase 2α in the Drosophila circadian clock. Nature 420: 816.
30. Liu A.C., Welsh D.K., Ko C.H., Tran H.G., Zhang E.E., Priest A.A., Buhr E.D., Singer O., Meeker K., Verma I.M., Doyle F.J., III, Takahashi J.S., and Kay S.A. 2007. Intercellular coupling confers robustness against mutations in the SCN circadian clock network. Cell 129: 605.
31. Liu X., Zwiebel L.J., Hinton D., Benzer S., Hall J.C., and Rosbash M. 1992. The period gene encodes a predominantly nuclear protein in adult Drosophila. J. Neurosci. 12: 2735.
32. Liu Y., Tsinoremas N.F., Johnson C.H., Lebedeva N.V., Golden S.S., Ishiura M., and Kondo T. 1995. Circadian orchestration of gene expression in cyanobacteria. Genes Dev. 9: 1469.
33. Lowrey P.L., Shimomura K., Antoch M.P., Yamazaki S., Zemenides P.D., Ralph M.R., Menaker M., and Takahashi J.S. 2000. Positional syntenic cloning and functional characterization of the mammalian circadian mutation tau. Science 288: 483.
34. Matsumoto A., Ukai-Tadenuma M., Yamada R.G., Houl J., Uno K.D., Kasukawa T., Dauwalder B., Itoh T.Q., Takahashi K., Ueda R., Hardin P.E., Tanimura T., and Ueda H.R. 2007. A functional genomics strategy reveals clockwork orange as a transcriptional regulator in the Drosophila circadian clock. Genes Dev. 21: 1687.
35. McClung C.R. 2007. A cyanobacterial circadian clock is based on the intrinsic ATPase activity of KaiC. Proc. Natl. Acad. Sci. 104: 16727.
36. McDonald M.J. and Rosbash M. 2001. Microarray analysis and organization of circadian gene expression in Drosophila. Cell 107: 567.
37. Mihalcescu I., Hsing W., and Leibler S. 2004. Resilient circadian oscillator revealed in individual cyanobacteria. Nature 430: 81.
38. Myers M.P., Wager-Smith K., Wesley C.S., Young M.W., and Sehgal A. 1995. Positional cloning and sequence analysis of the Drosophila clock gene, timeless. Science 270: 805.
39. Nakajima M., Imai K., Ito H., Nishiwaki T., Murayama Y., Iwasaki H., Oyama T., and Kondo T. 2005. Reconstitution of circadian oscillation of cyanobacterial KaiC phosphorylation in vitro. Science 308: 414.
40. Nawathean P., Stoleru D., and Rosbash M. 2007. A small conserved domain of Drosophila PERIOD is important for circadian phosphorylation, nuclear localization, and transcriptional repressor activity. Mol. Cell. Biol. 27: 5002.
41. Nishiwaki T., Satomi Y., Kitayama Y., Terauchi K., Kiyohara R., Takao T., and Kondo T. 2007. A sequential program of dual phosphorylation of KaiC as a basis for circadian rhythm in cyanobacteria. EMBO J. 26: 4029.
42. Peng Y., Stoleru D., Levine J.D., Hall J.C., and Rosbash M. 2003. Drosophila free-running rhythms require intercellular communication. PLoS Biol. 1: E13.
43. Pichaud F., Treisman J., and Desplan C. 2001. Reinventing a common strategy for patterning the eye. Cell 105: 9.
44. Price J.L., Blau J., Rothenfluh-Hilfiker A., Abodeely M., Kloss B., and Young M.W. 1998. double-time is a novel Drosophila clock gene that regulates PERIOD protein accumulation. Cell 94: 83.
45. Reddy P., Jacquier A.C., Abovich N., Petersen G., and Rosbash M. 1986. The period clock locus of D. melanogaster codes for a proteoglycan. Cell 46: 53.
46. Reddy P., Zehring W.A., Wheeler D.A., Pirrotta V., Hadfield C., Hall J.C., and Rosbash M. 1984. Molecular analysis of the period locus in Drosophila melanogaster and identification of a transcript involved in biological rhythms. Cell 38: 701.
47. Reyes H., Reisz-Porszasz S., and Hankinson O. 1992. Identification of the Ah receptor nuclear translocator protein (Arnt) as a component of the DNA binding form of the Ah receptor. Science 256: 1193.
48. Rust M.J., Markson J.S., Lane W.S., Fisher D.S., and O'Shea E.K. 2007. Ordered phosphorylation governs oscillation of a three-protein circadian clock. Science 318: 809.
49. Rutila J.E., Suri V., Le M., So W.V., Rosbash M., and Hall J.C. 1998. CYCLE is a second bHLH-PAS clock protein essential for circadian rhythmicity and transcription of Drosophila period and timeless. Cell 93: 805.
50. Sehgal A., Rothenfluh-Hilfiker A., Hunter-Ensor M., Chen Y., Myers M., and Young M.W. 1995. Rhythmic expression of timeless: A basis for promoting circadian cycles in period gene autoregulation. Science 270: 808.
51. Shin H.-S., Bargiello T.A., Clark B.T., Jackson F.R., and Young M.W. 1985. An unusual coding sequence from a Drosophila clock gene is conserved in vertebrates. Nature 317: 445.
52. Smith R.F. and Konopka R.J. 1982. Effects of dosage alterations at the per locus on the period of the circadian clock of Drosophila. Mol. Gen. Genet. 185: 30.
53. Stoleru D., Peng Y., Agosto J., and Rosbash M. 2004. Coupled oscillators control morning and evening locomotor behaviour of Drosophila. Nature 431: 862.
54. Stoleru D., Peng Y., Nawathean P., and Rosbash M. 2005. A resetting signal between Drosophila pacemakers synchronizes morning and evening activity. Nature 438: 238.
55. Stoleru D., Nawathean P., de la Paz Fernández M., Menet J.S., Ceriani M.F., and Rosbash M. 2007. The Drosophila circadian network is a seasonal timer. Cell 129: 207.
56. Sun Z.S., Albrecht U., Zhuchenko O., Bailey J., Eichele G., and Lee C.C. 1997. RIGUI, a putative mammalian ortholog of the Drosophila period gene. Cell 90: 1003.
57. Tei H., Okamura H., Shigeyoshi Y., Fukuhara C., Ozawa R., Hirose M., and Sakaki Y. 1997. Circadian oscillation of a mammalian homologue of the Drosophila period gene. Nature 389: 512.
58. Terauchi K., Kitayama Y., Nishiwaki T., Miwa K., Murayama Y., Oyama T., and Kondo T. 2007. ATPase activity of KaiC determines the basic timing for circadian clock of cyanobacteria. Proc. Natl. Acad. Sci. 104: 16377.
59. Tomita J., Nakajima M., Kondo T., and Iwasaki H. 2005. No transcription-translation feedback in circadian rhythm of KaiC phosphorylation. Science 307: 251.
60. Welsh D.K., Logothetis D.E., Meister M., and Reppert S.M. 1995. Individual neurons dissociated from rat suprachiasmatic nucleus express independently phased circadian firing rhythms. Neuron 14: 697.
61. Woelfle M.A. and Johnson C.H. 2006. No promoter left behind: Global circadian gene expression in cyanobacteria. J. Biol. Rhythms 21: 419.
62. Yang Z. and Sehgal A. 2001. Role of molecular oscillations in generating behavioral rhythms in Drosophila. Neuron 29: 453.
63. Yu Q., Colot H.V., Kyriacou C.P., Hall J.C., and Rosbash M. 1987. Behaviour modification by in vitro mutagenesis of a variable region within the period gene of Drosophila. Nature 326: 765.
64. Yu W., Zheng H., Houl J.H., Dauwalder B., and Hardin P.E. 2006. PER-dependent rhythms in CLK phosphorylation and E-box binding regulate circadian transcription. Genes Dev. 20: 723.
65. Zehring W.A., Wheeler D.A., Reddy P., Konopka R.J., Kyriacou C.P., Rosbash M., and Hall J.C. 1984. P-element transformation with period locus DNA restores rhythmicity to mutant, arrhythmic Drosophila melanogaster. Cell 39: 369.
66. Zeng H., Qian Z., Myers M.P., and Rosbash M. 1996. A lightentrainment mechanism for the Drosophila circadian clock. Nature 380: 129.
67. Zhao J., Kilman V.L., Keegan K.P., Peng Y., Emery P., Rosbash M., and Allada R. 2003. Drosophila clock can generate ectopic circadian clocks. Cell 113: 755.