Ultradian oscillators in somite segmentation and other biological events

Cold Spring Harbor Symposia on Quantitative Biology

Volumn 72, Issue , 2007, Pages 451-457

  Kageyama, R ^a,b   Yoshiura, S ^a,b   Masamizu, Y ^a,b   Niwa, Y ^a,b  

^a KYOTO UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

HELIX LOOP HELIX PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HES; TRANSCRIPTION FACTOR HES 1; TRANSCRIPTION FACTOR HES 7; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; HES1 PROTEIN, MOUSE; HES7 PROTEIN, MOUSE; HOMEODOMAIN PROTEIN; SMAD PROTEIN; STAT3 PROTEIN; SUPPRESSOR OF CYTOKINE SIGNALING;

BIOLOGICAL RHYTHM; CELL CYCLE; CELL CYCLE G1 PHASE; CELL PROLIFERATION; CELLS BY BODY ANATOMY; EMBRYO DEVELOPMENT; EMBRYO SEGMENTATION; FIBROBLAST; GENE LOSS; GENE PRODUCT; IMAGING SYSTEM; MATHEMATICAL MODEL; NEGATIVE FEEDBACK; NEUROBLAST; NONHUMAN; OSCILLATION; PERIODICITY; PROTEIN DEGRADATION; SIMULATION; SOMITE; STABLE EXPRESSION; ULTRADIAN RHYTHM; ANIMAL; BIOLOGICAL MODEL; CYTOLOGY; FEEDBACK SYSTEM; GENETICS; MORPHOGENESIS; MOUSE; PHYSIOLOGY; PRENATAL DEVELOPMENT; REVIEW; SIGNAL TRANSDUCTION;

ACTIVITY CYCLES; ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; BODY PATTERNING; CELL CYCLE; FEEDBACK, BIOCHEMICAL; HOMEODOMAIN PROTEINS; MICE; MODELS, BIOLOGICAL; SIGNAL TRANSDUCTION; SMAD PROTEINS; SOMITES; STAT3 TRANSCRIPTION FACTOR; SUPPRESSOR OF CYTOKINE SIGNALING PROTEINS;

EID: 48249105439     PISSN: 00917451     EISSN: None     Source Type: Book Series    
DOI: 10.1101/sqb.2007.72.012     Document Type: Conference Paper

References (42)

1. Aulehla A. and Herrmann B.G. 2004. Segmentation in vertebrates: Clock and gradient finally joined. Genes Dev. 18: 2060.
2. Baek J.H., Hatakeyama J., Sakamoto S., Ohtsuka T., and Kageyama R. 2006. Persistent and high levels of Hes1 expression regulate boundary formation in the developing central nervous system. Development 133: 2467.
3. Bar-Or R.L., Maya R., Segel L.A., Alon U., Levine A.J., and Oren M. 2000. Generation of oscillations by the p53-Mdm2 feedback loop: A theoretical and experimental study. Proc. Natl. Acad. Sci. 97: 11250.
4. Bessho Y. and Kageyama R. 2003. Oscillations, clocks and segmentation. Curr. Opin. Genet. Dev. 13: 379.
5. Bessho Y., Hirata H., Masamizu Y., and Kageyama R. 2003. Periodic repression by the bHLH factor Hes7 is an essential mechanism for the somite segmentation clock. Genes Dev. 17: 1451.
6. Bessho Y., Miyoshi G., Sakata R., and Kageyama R. 2001a. Hes7: A bHLH-type repressor gene regulated by Notch and expressed in the presomitic mesoderm. Genes Cells 6: 175.
7. Bessho Y., Sakata R., Komatsu S., Shiota K., Yamada S., and Kageyama R. 2001b. Dynamic expression and essential functions of Hes7 in somite segmentation. Genes Dev. 15: 2642.
8. Brückner K., Perez L., Clausen H., and Cohen S. 2000. Glycosyltransferase activity of Fringe modulates Notch-Delta interactions. Nature 406: 411.
9. Dequéant M.-L. Glynn E., Gaudenz K., Wahl M., Chen J., Mushegian A., and Pourquié O. 2006. A complex oscillating network of signaling genes underlies the mouse segmentation clock. Science 314: 1595.
10. Evrard Y.A., Lun Y., Aulehla A., Gan L., and Johnson R.L. 1998. lunatic fringe is an essential mediator of somite segmentation and patterning. Nature 394: 377.
11. Gridley T. 2006. The long and short of it: Somite formation in mice. Dev. Dyn. 235: 2330.
12. Hirata H., Bessho Y., Kokubu H., Masamizu Y., Yamada S., Lewis J., and Kageyama R. 2004. Instability of Hes7 protein is crucial for the somite segmentation clock. Nat. Genet. 36: 750.
13. Hirata H., Yoshiura S., Ohtsuka T., Bessho Y., Harada T., Yoshikawa K., and Kageyama R. 2002. Oscillatory expression of the bHLH factor Hes1 regulated by a negative feedback loop. Science 298: 840.
14. Hoffmann A., Levchenko A., Scott M.L., and Baltimore D. 2002. The IκB-NF-κB signaling module: Temporal control and selective gene activation. Science 298: 1241.
15. Horikawa K., Ishimatsu K., Yoshimoto E., Kondo S., and Takeda H. 2006. Noise-resistant and synchronized oscillation of the segmentation clock. Nature 441: 719.
16. Imamura T., Takase M., Nishihara A., Oeda E., Hanai J., Kawabata M., and Miyazono K. 1997. Smad6 inhibits signalling by the TGF-β superfamily. Nature 389: 622.
17. Jensen M.H., Sneppen K., and Tiana G. 2003. Sustained oscillations and time delays in gene expression of protein Hes1. FEBS Lett. 541: 176.
18. Jiang Y.J., Aerne B.L., Smithers L., Haddon C., Ish-Horowicz D., and Lewis J. 2000. Notch signalling and the synchronization of the somite segmentation clock. Nature 408: 475.
19. Jouve C., Palmeirim I., Henrique D., Beckers J., Gossler A., Ish-Horowicz D., and Pourquié O. 2000. Notch signalling is required for cyclic expression of the hairy-like gene HES1 in the presomitic mesoderm. Development 127: 1421.
20. Kamakura S., Oishi K., Yoshimatsu T., Nakafuku M., Masuyama N., and Gotoh Y. 2004. Hes binding to STAT3 mediates crosstalk between Notch and JAK-STAT signaling. Nat. Cell Biol. 6: 547.
21. Kageyama R., Masamizu Y., and Niwa Y. 2007a. Oscillator mechanism of Notch pathway in the segmentation clock. Dev. Dyn. 236: 1403.
22. Kageyama R., Ohtsuka T., and Kobayashi T. 2007b. The Hes gene family: Repressors and oscillators that orchestrate embryogenesis. Development 134: 1243.
23. Lahav G., Rosenfeld N., Sigal A., Geva-Zatorsky N., Levine A.J., Elowitz M.B., and Alon U. 2004. Dynamics of the p53-Mdm2 feedback loop in individual cells. Nat. Genet. 36: 147.
24. Levy D.E. and Darnell J.E., Jr. 2002. Stats: Transcriptional control and biological impact. Nat. Rev. Mol. Cell Biol. 3: 651.
25. Lewis J. 2003. Autoinhibition with transcriptional delay: A simple mechanism for the zebrafish somitogenesis oscillator. Curr. Biol. 13: 1398.
26. Masamizu Y., Ohtsuka T., Takashima Y., Nagahara H., Takenaka Y., Yoshikawa K., Okamura H., and Kageyama R. 2006. Real-time imaging of the somite segmentation clock: Revelation of unstable oscillators in the individual presomitic mesoderm cells. Proc. Natl. Acad. Sci. 103: 1313.
27. Massagué J. and Wotton D. 2000. Transcriptional control by the TGF-β/Smad signaling system. EMBO J. 19: 1745.
28. Moloney D.J., Panin V.M., Johnston S.H., Chen J., Shao L., Wilson R., Wang Y., Stanley P., Irvine K.D., Haltiwanger R.S., and Vogt T.F. 2000. Fringe is a glycosyltransferase that modifies Notch. Nature 406: 369.
29. Monk N.A. 2003. Oscillatory expression of Hes1, p53, and NF-κB driven by transcriptional time delays. Curr. Biol. 13: 1409.
30. Nelson D.E., Ihekwaba A.E., Elliott M., Johnson J.R., Gibney C.A., Foreman B.E., Nelson G., See V., Horton C.A., Spiller D.G., Edwards S.W., McDowell H.P., Unitt J.F., Sullivan E., Grimley R., Benson N., Broomhead D., Kell D.B., and White M.R. 2004. Oscillations in NF-κB signaling control the dynamics of gene expression. Science 306: 704.
31. Niwa Y., Masamizu Y., Liu T., Nakayama R., Deng C.-X., and Kageyama R. 2007. The initiation and propagation of Hes7 oscillation are cooperatively regulated by Fgf and Notch signaling in the somite segmentation clock. Dev. Cell 13: 298.
32. Pourquié O. 2003. The segmentation clock: Converting embryonic time into spatial pattern. Science 301: 328.
33. Sasai Y., Kageyama R., Tagawa Y., Shigemoto R., and Nakanishi S. 1992. Two mammalian helix-loop-helix factors structurally related to Drosophila hairy and Enhancer of split. Genes Dev. 6: 2620.
34. Serth K., Schuster-Gossler K., Cordes R., and Gossler A. 2003. Transcriptional oscillation of Lunatic fringe is essential for somitogenesis. Genes Dev. 17: 912.
35. Simon C., Follenius M., and Brandenberger G. 1987. Postprandial oscillations of plasma glucose, insulin and Cpeptide in man. Diabetologia 30: 769.
36. Starr R., Willson T.A., Viney E.M., Murray L.J., Rayner J.R., Jenkins B.J., Gonda T.J., Alexander W.S., Metcalf D., Nicola N.A., and Hilton D.J. 1997. A family of cytokine-inducible inhibitors of signalling. Nature 387: 917.
37. Takebayashi K., Sasai Y., Sakai Y., Watanabe T., Nakanishi S., and Kageyama R. 1994. Structure, chromosomal locus, and promoter analysis of the gene encoding the mouse helix-loophelix factor HES-1: Negative autoregulation through the multiple N box elements. J. Biol. Chem. 269: 5150.
38. Tannenbaum G.S. and Martin J.B. 1976. Evidence for an endogenous ultradian rhythm governing growth hormone secretion in the rat. Endocrinology 98: 562.
39. ten Dijke P., Miyazono K., and Heldin C.-H. 2000. Signaling inputs converge on nuclear effectors in TGF-β signaling. Trends Biosci. 25: 64.
40. Yoshiura S., Ohtsuka T., Takenaka Y., Nagahara H., Yoshikawa K., and Kageyama R. 2007. Ultradian oscillations of Stat, Smad and Hes1 expression in response to serum. Proc. Natl. Acad. Sci. 104: 11292.
41. Yu H. and Jove R. 2004. The STATS of cancer: New molecular targets come of age. Nat. Rev. Cancer 4: 97.
42. Zhang N. and Gridley T. 1998. Defects in somite formation in lunatic fringe-deficient mice. Nature 394: 374.