-
1
-
-
0032211804
-
ECM signalling: orchestrating cell behaviour and misbehaviour
-
Lukashev M.E., and Werb Z. ECM signalling: orchestrating cell behaviour and misbehaviour. Trends Cell Biol. 8 (1998) 437-441
-
(1998)
Trends Cell Biol.
, vol.8
, pp. 437-441
-
-
Lukashev, M.E.1
Werb, Z.2
-
2
-
-
33644751775
-
Emilin1 links TGF-beta maturation to blood pressure homeostasis
-
Zacchigna L., et al. Emilin1 links TGF-beta maturation to blood pressure homeostasis. Cell 124 (2006) 929-942
-
(2006)
Cell
, vol.124
, pp. 929-942
-
-
Zacchigna, L.1
-
3
-
-
34948867738
-
The collagen family members as cell adhesion proteins
-
Heino J. The collagen family members as cell adhesion proteins. BioEssays 29 (2007) 1001-1010
-
(2007)
BioEssays
, vol.29
, pp. 1001-1010
-
-
Heino, J.1
-
4
-
-
0031661502
-
The role of laminins in basement membrane function
-
Aumailley M., and Smyth N. The role of laminins in basement membrane function. J. Anat. 193 (1998) 1-21
-
(1998)
J. Anat.
, vol.193
, pp. 1-21
-
-
Aumailley, M.1
Smyth, N.2
-
5
-
-
0037686257
-
Fibulins: a versatile family of extracellular matrix proteins
-
Timpl R., et al. Fibulins: a versatile family of extracellular matrix proteins. Nat. Rev. Mol. Cell Biol. 4 (2003) 479-489
-
(2003)
Nat. Rev. Mol. Cell Biol.
, vol.4
, pp. 479-489
-
-
Timpl, R.1
-
6
-
-
0038575444
-
Functional structure and composition of the extracellular matrix
-
Bosman F.T., and Stamenkovic I. Functional structure and composition of the extracellular matrix. J. Pathol. 200 (2003) 423-428
-
(2003)
J. Pathol.
, vol.200
, pp. 423-428
-
-
Bosman, F.T.1
Stamenkovic, I.2
-
7
-
-
0242710145
-
Collagens - structure, function and biosynthesis
-
Gelse K., Poschl E., and Aigner T. Collagens - structure, function and biosynthesis. Adv. Drug Deliv. Rev. 55 (2003) 1531-1546
-
(2003)
Adv. Drug Deliv. Rev.
, vol.55
, pp. 1531-1546
-
-
Gelse, K.1
Poschl, E.2
Aigner, T.3
-
8
-
-
0035188727
-
How matrix metalloproteinases regulate cell behaviour
-
Sternlicht M.D., and Werb Z. How matrix metalloproteinases regulate cell behaviour. Annu. Rev. Cell. Dev. Biol. 17 (2001) 463-516
-
(2001)
Annu. Rev. Cell. Dev. Biol.
, vol.17
, pp. 463-516
-
-
Sternlicht, M.D.1
Werb, Z.2
-
9
-
-
0038771156
-
Tales from the crypt(ic) sites of the extracellular matrix
-
Schenk S., and Quaranta V. Tales from the crypt(ic) sites of the extracellular matrix. Trends Cell Biol. 13 (2003) 366-375
-
(2003)
Trends Cell Biol.
, vol.13
, pp. 366-375
-
-
Schenk, S.1
Quaranta, V.2
-
10
-
-
1942467843
-
Extracellular matrix proteins modulate asthmatic airway smooth muscle cell proliferation via an autcrine mechanism
-
Johnson P.R.A., et al. Extracellular matrix proteins modulate asthmatic airway smooth muscle cell proliferation via an autcrine mechanism. J. Allergy Clin. Immunol. 113 (2004) 690-696
-
(2004)
J. Allergy Clin. Immunol.
, vol.113
, pp. 690-696
-
-
Johnson, P.R.A.1
-
11
-
-
0035986760
-
AlphaVbeta3 integrin engagement enhances cell invasiveness in human multiple myeloma
-
Ria R., et al. AlphaVbeta3 integrin engagement enhances cell invasiveness in human multiple myeloma. Haematologica 98 (2002) 836-845
-
(2002)
Haematologica
, vol.98
, pp. 836-845
-
-
Ria, R.1
-
12
-
-
0037101624
-
Role for reelin in the development of granule cell dispersion in temporal lobe epilepsy
-
Haas C.A., et al. Role for reelin in the development of granule cell dispersion in temporal lobe epilepsy. J. Neurosci. 22 (2002) 5797-5802
-
(2002)
J. Neurosci.
, vol.22
, pp. 5797-5802
-
-
Haas, C.A.1
-
13
-
-
0037603589
-
Mutations in PCSK9 cause autosomal dominant hypercholesterolemia
-
Abifadel M., et al. Mutations in PCSK9 cause autosomal dominant hypercholesterolemia. Nat. Genet. 34 (2003) 154-156
-
(2003)
Nat. Genet.
, vol.34
, pp. 154-156
-
-
Abifadel, M.1
-
14
-
-
33748871007
-
ADAM15 upregulation and interaction with multiple binding partners in inflammatory bowel disease
-
Mosnier J.F., et al. ADAM15 upregulation and interaction with multiple binding partners in inflammatory bowel disease. Lab. Invest. 86 (2006) 1064-1073
-
(2006)
Lab. Invest.
, vol.86
, pp. 1064-1073
-
-
Mosnier, J.F.1
-
15
-
-
32244440192
-
Dystroglycan: from biosynthesis to pathogenesis of human disease
-
Barresu R., and Campbell K.P. Dystroglycan: from biosynthesis to pathogenesis of human disease. J. Cell Sci. 119 (2006) 199-207
-
(2006)
J. Cell Sci.
, vol.119
, pp. 199-207
-
-
Barresu, R.1
Campbell, K.P.2
-
16
-
-
33847242563
-
Pathobiology of osteoarthritis: pathomechanisms and potential therapeutic targets
-
Roach H.I., et al. Pathobiology of osteoarthritis: pathomechanisms and potential therapeutic targets. Curr. Drug Target. 8 (2007) 271-282
-
(2007)
Curr. Drug Target.
, vol.8
, pp. 271-282
-
-
Roach, H.I.1
-
17
-
-
0003103892
-
REELIN and schizophrenia: a disease at the interface of the genome and the epigenome
-
Costa E., et al. REELIN and schizophrenia: a disease at the interface of the genome and the epigenome. Mol. Intervent. 2 (2007) 47-57
-
(2007)
Mol. Intervent.
, vol.2
, pp. 47-57
-
-
Costa, E.1
-
18
-
-
4344686717
-
Extracellular matrix changes in stented human coronary arteries
-
Farb A., et al. Extracellular matrix changes in stented human coronary arteries. Circulation 110 (2004) 940-947
-
(2004)
Circulation
, vol.110
, pp. 940-947
-
-
Farb, A.1
-
19
-
-
0030973267
-
Deficient activity of von Willebrand factor-cleaving protease in chronic relapsing thrombotic thrombocytopenic purpura
-
Furlan M., et al. Deficient activity of von Willebrand factor-cleaving protease in chronic relapsing thrombotic thrombocytopenic purpura. Blood 89 (1997) 3097-3103
-
(1997)
Blood
, vol.89
, pp. 3097-3103
-
-
Furlan, M.1
-
20
-
-
34247615582
-
Integrins: novel therapeutic targets for cardiovascular diseases
-
Lal H., et al. Integrins: novel therapeutic targets for cardiovascular diseases. Cardiovasc. Hematol. Agents Med. Chem. 5 (2007) 109-132
-
(2007)
Cardiovasc. Hematol. Agents Med. Chem.
, vol.5
, pp. 109-132
-
-
Lal, H.1
-
21
-
-
34447520043
-
Matrix metalloproteases inhibitors as therapy for inflammatory and vascular diseases
-
Hu J., et al. Matrix metalloproteases inhibitors as therapy for inflammatory and vascular diseases. Nat. Rev. Drug Discov. 6 (2007) 480-498
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, pp. 480-498
-
-
Hu, J.1
-
22
-
-
33747606753
-
Early evolution of animal cell signalling and adhesion genes
-
Nichols S.A., et al. Early evolution of animal cell signalling and adhesion genes. Proc. Natl. Acad. Sci. U.S.A. 103 (2006) 12451-12456
-
(2006)
Proc. Natl. Acad. Sci. U.S.A.
, vol.103
, pp. 12451-12456
-
-
Nichols, S.A.1
-
23
-
-
21744445916
-
The integrins of the urochordate Ciona intestinalis provide novel insights into the molecular evolution of the vertebrate integrin family
-
Ewan R., et al. The integrins of the urochordate Ciona intestinalis provide novel insights into the molecular evolution of the vertebrate integrin family. BMC Evol. Biol. 5 (2005) 31
-
(2005)
BMC Evol. Biol.
, vol.5
, pp. 31
-
-
Ewan, R.1
-
24
-
-
21844444108
-
The characterisation of six ADAMTS proteases in the basal chordate Ciona intestinalis provides new insights into the vertebrate ADAMTS family
-
Huxley-Jones J., et al. The characterisation of six ADAMTS proteases in the basal chordate Ciona intestinalis provides new insights into the vertebrate ADAMTS family. Int. J. Biochem. Cell Biol. 37 (2005) 1838-1845
-
(2005)
Int. J. Biochem. Cell Biol.
, vol.37
, pp. 1838-1845
-
-
Huxley-Jones, J.1
-
25
-
-
34248549971
-
The evolution of the vertebrate metzincins, insights from Ciona intestinalis and Danio rerio
-
Huxley-Jones J., et al. The evolution of the vertebrate metzincins, insights from Ciona intestinalis and Danio rerio. BMC Evol. Biol. 7 (2007) 63
-
(2007)
BMC Evol. Biol.
, vol.7
, pp. 63
-
-
Huxley-Jones, J.1
-
27
-
-
18044373469
-
A genomic view of the complexity of mammalian proteolytic systems
-
Puente X.S., et al. A genomic view of the complexity of mammalian proteolytic systems. Biochem. Soc. Trans. 33 (2005) 331-334
-
(2005)
Biochem. Soc. Trans.
, vol.33
, pp. 331-334
-
-
Puente, X.S.1
-
29
-
-
33846164404
-
Emerging roles of cysteine cathepsins in disease and their potential as drug targets
-
Vasiljeva O., et al. Emerging roles of cysteine cathepsins in disease and their potential as drug targets. Curr. Pharm. Des. 13 (2007) 387-403
-
(2007)
Curr. Pharm. Des.
, vol.13
, pp. 387-403
-
-
Vasiljeva, O.1
-
30
-
-
84885379360
-
Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy
-
Overall C.M., and Kleifeld O. Validating matrix metalloproteinases as drug targets and anti-targets for cancer therapy. Nat. Rev. Cancer 6 (2006) 239-277
-
(2006)
Nat. Rev. Cancer
, vol.6
, pp. 239-277
-
-
Overall, C.M.1
Kleifeld, O.2
-
31
-
-
0035941359
-
Matrix metalloproteinase activity inactivates the CXC chemokine stromal cell derived factor-1
-
McQuibban G.A., et al. Matrix metalloproteinase activity inactivates the CXC chemokine stromal cell derived factor-1. J. Biol. Chem. 276 (2001) 43503-43508
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 43503-43508
-
-
McQuibban, G.A.1
-
32
-
-
34447525057
-
Microenvironmental regulation of biomacromolecular therapies
-
Kong H.J., and Mooney D.J. Microenvironmental regulation of biomacromolecular therapies. Nat. Rev. Drug Discov. 6 (2007) 455-463
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, pp. 455-463
-
-
Kong, H.J.1
Mooney, D.J.2
-
33
-
-
0035405886
-
Metalloproteinases in biology and pathology of the nervous system
-
Yong V.W., et al. Metalloproteinases in biology and pathology of the nervous system. Nat. Rev. Neurosci. 2 (2001) 502-511
-
(2001)
Nat. Rev. Neurosci.
, vol.2
, pp. 502-511
-
-
Yong, V.W.1
-
34
-
-
0034786695
-
Composition and structure of articular cartilage: a template for tissue repair
-
Poole A.R., et al. Composition and structure of articular cartilage: a template for tissue repair. Clin. Orthop. Relat. Res. 391 (2001) S26-S33
-
(2001)
Clin. Orthop. Relat. Res.
, vol.391
-
-
Poole, A.R.1
-
35
-
-
35548952181
-
Dilation and degradation of the brain extracellular matrix enhances penetration of infused polymer nanoparticles
-
Neeves K.B., et al. Dilation and degradation of the brain extracellular matrix enhances penetration of infused polymer nanoparticles. Brain Res. 1180 (2007) 121-132
-
(2007)
Brain Res.
, vol.1180
, pp. 121-132
-
-
Neeves, K.B.1
-
36
-
-
1842740222
-
Similarity of binding sites of human matrix metalloproteinases
-
Lukacova V., et al. Similarity of binding sites of human matrix metalloproteinases. J. Biol. Chem. 279 (2004) 14194-14200
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 14194-14200
-
-
Lukacova, V.1
-
37
-
-
0034772722
-
Phase I and pharmacological study of the oral matrix metalloproteinase inhibitor MMI270 (CGS27023A) in patients with advanced solid cancer
-
Levitt N.C., et al. Phase I and pharmacological study of the oral matrix metalloproteinase inhibitor MMI270 (CGS27023A) in patients with advanced solid cancer. Clin. Cancer Res. 7 (2001) 1912-1922
-
(2001)
Clin. Cancer Res.
, vol.7
, pp. 1912-1922
-
-
Levitt, N.C.1
-
38
-
-
0035030734
-
The design, structure and therapeutic application of matrix metalloproteinase inhibitors
-
Skiles J.W., et al. The design, structure and therapeutic application of matrix metalloproteinase inhibitors. Curr. Med. Chem. 8 (2001) 425-474
-
(2001)
Curr. Med. Chem.
, vol.8
, pp. 425-474
-
-
Skiles, J.W.1
-
39
-
-
33847195428
-
Matrix metalloproteinases and the regulation of tissue remodelling
-
Page-McCaw A., et al. Matrix metalloproteinases and the regulation of tissue remodelling. Nat. Rev. Mol. Cell Biol. 8 (2007) 221-233
-
(2007)
Nat. Rev. Mol. Cell Biol.
, vol.8
, pp. 221-233
-
-
Page-McCaw, A.1
-
40
-
-
29144483936
-
Predicting protein druggability
-
Hajduk P.J., et al. Predicting protein druggability. Drug Discov. Today 10 (2005) 1675-1682
-
(2005)
Drug Discov. Today
, vol.10
, pp. 1675-1682
-
-
Hajduk, P.J.1
-
41
-
-
29144531173
-
The druggable genome: an update
-
Russ A.P., and Lampel S. The druggable genome: an update. Drug Discov. Today 10 (2005) 1607-1610
-
(2005)
Drug Discov. Today
, vol.10
, pp. 1607-1610
-
-
Russ, A.P.1
Lampel, S.2
-
42
-
-
34249650211
-
Druggability of human disease genes
-
Sakharkar M.K., et al. Druggability of human disease genes. Int. J. Biochem. Cell Biol. 39 (2007) 1156-1164
-
(2007)
Int. J. Biochem. Cell Biol.
, vol.39
, pp. 1156-1164
-
-
Sakharkar, M.K.1
-
43
-
-
33751547539
-
How many drug targets are there?
-
Overington J.P., et al. How many drug targets are there?. Nat. Rev. Drug Discov. 5 (2006) 993-996
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 993-996
-
-
Overington, J.P.1
-
44
-
-
0026772036
-
A defect of platelet aggregation associated with an abnormal distribution of glycoprotein IIb-IIIa complexes within the platelet: the cause of a lifelong bleeding disorder
-
Hardisty R., et al. A defect of platelet aggregation associated with an abnormal distribution of glycoprotein IIb-IIIa complexes within the platelet: the cause of a lifelong bleeding disorder. Blood 80 (1992) 696-708
-
(1992)
Blood
, vol.80
, pp. 696-708
-
-
Hardisty, R.1
-
45
-
-
17344372250
-
Mutations in the integrin alpha-7 gene cause congenital myopathy
-
Hayashi Y.K., et al. Mutations in the integrin alpha-7 gene cause congenital myopathy. Nat. Genet. 19 (1998) 94-97
-
(1998)
Nat. Genet.
, vol.19
, pp. 94-97
-
-
Hayashi, Y.K.1
-
46
-
-
0029908558
-
Absence of integrin alpha-6 leads to epidermolysis bullosa and neonatal death in mice
-
Georges-Labouesse E., et al. Absence of integrin alpha-6 leads to epidermolysis bullosa and neonatal death in mice. Nat. Genet. 13 (1996) 370-373
-
(1996)
Nat. Genet.
, vol.13
, pp. 370-373
-
-
Georges-Labouesse, E.1
-
47
-
-
0035835487
-
Plasma hyaluronidase (HYAL-1) promotes tumor cell cycling
-
Lin G., and Stern R. Plasma hyaluronidase (HYAL-1) promotes tumor cell cycling. Cancer Lett. 163 (2001) 95-101
-
(2001)
Cancer Lett.
, vol.163
, pp. 95-101
-
-
Lin, G.1
Stern, R.2
-
48
-
-
38449109697
-
Mucoactive agents for airway mucus hypersecretory diseases
-
Rogers D.F. Mucoactive agents for airway mucus hypersecretory diseases. Respir. Care 52 (2007) 1176-1193
-
(2007)
Respir. Care
, vol.52
, pp. 1176-1193
-
-
Rogers, D.F.1
-
49
-
-
33746903085
-
Targeting RGD recognizing integrins: drug development, biomaterial research, tumor imaging and targeting
-
Meyer A., et al. Targeting RGD recognizing integrins: drug development, biomaterial research, tumor imaging and targeting. Curr. Pharm. Des. 12 (2006) 2723-2747
-
(2006)
Curr. Pharm. Des.
, vol.12
, pp. 2723-2747
-
-
Meyer, A.1
-
50
-
-
0042855996
-
The integrin alpha V beta 3 and CD44 regulate the actions of osteopontin on osteoclast motility
-
Chellaiah M.A., and Hruska K.A. The integrin alpha V beta 3 and CD44 regulate the actions of osteopontin on osteoclast motility. Calc. Tissue Int. 72 (2003) 197-205
-
(2003)
Calc. Tissue Int.
, vol.72
, pp. 197-205
-
-
Chellaiah, M.A.1
Hruska, K.A.2
-
51
-
-
0035491691
-
Rheumatoid arthritis: new developments in the pathogenesis with special reference to synovial fibroblasts
-
Seemayer C.A., et al. Rheumatoid arthritis: new developments in the pathogenesis with special reference to synovial fibroblasts. Zeitschrift fur Rheumatologie 60 (2001) 309-318
-
(2001)
Zeitschrift fur Rheumatologie
, vol.60
, pp. 309-318
-
-
Seemayer, C.A.1
-
52
-
-
0031456703
-
Selective alpha(v)beta(3) integrin blockade potently limits neointimal hyperplasia and lumen stenosis following deep coronary arterial stent injury: Evidence for the functional importance of integrin alpha(v)beta(3) and osteopontin expression during neointima formation
-
Srivatsa S.S., et al. Selective alpha(v)beta(3) integrin blockade potently limits neointimal hyperplasia and lumen stenosis following deep coronary arterial stent injury: Evidence for the functional importance of integrin alpha(v)beta(3) and osteopontin expression during neointima formation. Cardiovasc. Res. 36 (1997) 408-428
-
(1997)
Cardiovasc. Res.
, vol.36
, pp. 408-428
-
-
Srivatsa, S.S.1
-
53
-
-
0029925079
-
Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor-type integrins inhibits retinal neovascularization
-
Hammes H.P., et al. Subcutaneous injection of a cyclic peptide antagonist of vitronectin receptor-type integrins inhibits retinal neovascularization. Nat. Med. 2 (1996) 529-533
-
(1996)
Nat. Med.
, vol.2
, pp. 529-533
-
-
Hammes, H.P.1
-
54
-
-
33751232015
-
Integrin binding characteristics of the disintegrin-like domain of ADAM15
-
Lu D., et al. Integrin binding characteristics of the disintegrin-like domain of ADAM15. Thromb. Haemost. 96 (2006) 642-651
-
(2006)
Thromb. Haemost.
, vol.96
, pp. 642-651
-
-
Lu, D.1
-
55
-
-
34447126346
-
ADAM15/metargidin mediates homotypic aggregation of human T lymphocytes and heterotypic interactions of T lymphocytes with intestinal epithelial cells
-
Charruer L., et al. ADAM15/metargidin mediates homotypic aggregation of human T lymphocytes and heterotypic interactions of T lymphocytes with intestinal epithelial cells. J. Biol. Chem. 282 (2007) 16948-16958
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 16948-16958
-
-
Charruer, L.1
-
56
-
-
38549096018
-
MEROPS: the peptidase database
-
Rawlings N.D., et al. MEROPS: the peptidase database. Nucleic Acids Res. 36 (2008) D320-D325
-
(2008)
Nucleic Acids Res.
, vol.36
-
-
Rawlings, N.D.1
-
57
-
-
0037077212
-
Proteolysis of latent transforming growth factor-b (TGF-b) binding protein-1 by osteoclasts
-
Dallas S.J., et al. Proteolysis of latent transforming growth factor-b (TGF-b) binding protein-1 by osteoclasts. J. Biol. Chem. 277 (2002) 21352-21360
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 21352-21360
-
-
Dallas, S.J.1
-
58
-
-
33749452709
-
Tenascin-C induced signaling in cancer
-
Orend G., and Chiquet-Erismann R. Tenascin-C induced signaling in cancer. Cancer Lett. 244 (2006) 143-163
-
(2006)
Cancer Lett.
, vol.244
, pp. 143-163
-
-
Orend, G.1
Chiquet-Erismann, R.2
-
59
-
-
18644384411
-
Transmembrane collagen XVII, an epithelial adhesion protein, is shed from the cell surface by ADAMs
-
Franzke C.-W., et al. Transmembrane collagen XVII, an epithelial adhesion protein, is shed from the cell surface by ADAMs. EMBO J. 21 (2002) 5026-5035
-
(2002)
EMBO J.
, vol.21
, pp. 5026-5035
-
-
Franzke, C.-W.1
-
60
-
-
33749538647
-
BMP1 controls TGFb1 activation via cleavage of latent TGFb-binding protein
-
Ge G., and Greenspan D.S. BMP1 controls TGFb1 activation via cleavage of latent TGFb-binding protein. J. Cell Biol. 175 (2006) 111-120
-
(2006)
J. Cell Biol.
, vol.175
, pp. 111-120
-
-
Ge, G.1
Greenspan, D.S.2
-
61
-
-
34249681972
-
Identification of an ADAMTS-4 cleavage motif using phage display leads to the development of fluorogenic peptide substrates and reveals Matrilin-3 as a novel substrate
-
Hills R., et al. Identification of an ADAMTS-4 cleavage motif using phage display leads to the development of fluorogenic peptide substrates and reveals Matrilin-3 as a novel substrate. J. Biol. Chem. 282 (2007) 11101-11109
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 11101-11109
-
-
Hills, R.1
-
62
-
-
11144346764
-
The promise of genomics to identify novel therapeutic targets
-
Orth A.P., et al. The promise of genomics to identify novel therapeutic targets. Exp. Opin. Therap. Targets 8 (2004) 587-596
-
(2004)
Exp. Opin. Therap. Targets
, vol.8
, pp. 587-596
-
-
Orth, A.P.1
-
63
-
-
0031574072
-
The CLUSTALX windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools
-
Thompson J.D., et al. The CLUSTALX windows interface: flexible strategies for multiple sequence alignment aided by quality analysis tools. Nucleic Acids Res. 24 (1997) 4877-4882
-
(1997)
Nucleic Acids Res.
, vol.24
, pp. 4877-4882
-
-
Thompson, J.D.1
|