-
1
-
-
1542269164
-
The impact of the completed human genome sequence on the development of novel therapeutics for human disease
-
Austin C.P. The impact of the completed human genome sequence on the development of novel therapeutics for human disease. Annul. Rev. Med. 55 (2003) 1-13
-
(2003)
Annul. Rev. Med.
, vol.55
, pp. 1-13
-
-
Austin, C.P.1
-
2
-
-
33644876924
-
Ensembl 2006
-
Birney E., Andrews D., Caccamo M., Chen Y., Clarke L., Coates G., et al. Ensembl 2006. Nucleic Acids Res. 34 (2006) D556-D561
-
(2006)
Nucleic Acids Res.
, vol.34
-
-
Birney, E.1
Andrews, D.2
Caccamo, M.3
Chen, Y.4
Clarke, L.5
Coates, G.6
-
3
-
-
15944382704
-
TRbase: a database relating tandem repeats to disease genes for the human genome
-
Boby T., Patch A.M., and Aves S.J. TRbase: a database relating tandem repeats to disease genes for the human genome. Bioinformatics 21 (2005) 811-816
-
(2005)
Bioinformatics
, vol.21
, pp. 811-816
-
-
Boby, T.1
Patch, A.M.2
Aves, S.J.3
-
4
-
-
0037373275
-
Discovering genotypes underlying human phenotypes: past successes for mendelian disease Future approaches for complex disease
-
Botstein D., and Risch N. Discovering genotypes underlying human phenotypes: past successes for mendelian disease Future approaches for complex disease. Nat. Genet. 33 (2003) 228-237
-
(2003)
Nat. Genet.
, vol.33
, pp. 228-237
-
-
Botstein, D.1
Risch, N.2
-
6
-
-
33745215858
-
Integrative pharmacology and drug discovery-is the tide finally turning?
-
Collis M.C. Integrative pharmacology and drug discovery-is the tide finally turning?. Nat. Rev. Drug Discov. 5 (2006) 377-379
-
(2006)
Nat. Rev. Drug Discov.
, vol.5
, pp. 377-379
-
-
Collis, M.C.1
-
7
-
-
33644876020
-
Pfam: clans, web tools and services
-
Finn R.D., Mistry J., Schuster-Bockler B., Griffiths-Jones S., Hollich V., Lassmann T., et al. Pfam: clans, web tools and services. Nucleic Acids Res. 34 (2006) D247-D251
-
(2006)
Nucleic Acids Res.
, vol.34
-
-
Finn, R.D.1
Mistry, J.2
Schuster-Bockler, B.3
Griffiths-Jones, S.4
Hollich, V.5
Lassmann, T.6
-
8
-
-
0345363156
-
Genatlas database, genes and development defects
-
Frezal J. Genatlas database, genes and development defects. C. R. Acad. Sci. III 321 (1998) 805-817
-
(1998)
C. R. Acad. Sci. III
, vol.321
, pp. 805-817
-
-
Frezal, J.1
-
9
-
-
33748751182
-
Chemogenomics: structuring the drug discovery process to gene families
-
Harris C.J., and Stevens A.P. Chemogenomics: structuring the drug discovery process to gene families. Drug Discov. Today 11 (2006) 880-888
-
(2006)
Drug Discov. Today
, vol.11
, pp. 880-888
-
-
Harris, C.J.1
Stevens, A.P.2
-
12
-
-
13444266370
-
Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders
-
Hamosh A., Scott A.F., Amberger J.S., Bocchini C.A., and McKusick V.A. Online Mendelian Inheritance in Man (OMIM), a knowledgebase of human genes and genetic disorders. Nucleic Acids Res. 33 (2005) D514-D517
-
(2005)
Nucleic Acids Res.
, vol.33
-
-
Hamosh, A.1
Scott, A.F.2
Amberger, J.S.3
Bocchini, C.A.4
McKusick, V.A.5
-
13
-
-
4844229391
-
Evolutionary conservation and selection of human disease gene orthologs in the rat and mouse genomes
-
Huang H., Winter E.E., Wang H., Weinstock K.G., Xing H., Goodstadt L., et al. Evolutionary conservation and selection of human disease gene orthologs in the rat and mouse genomes. Genome Biol. 5 (2004) R47
-
(2004)
Genome Biol.
, vol.5
-
-
Huang, H.1
Winter, E.E.2
Wang, H.3
Weinstock, K.G.4
Xing, H.5
Goodstadt, L.6
-
15
-
-
3543106033
-
Genome-wide identification of genes likely to be involved in human genetic disease
-
Lopez-Bigas N., and Ouzounis C.A. Genome-wide identification of genes likely to be involved in human genetic disease. Nucleic Acids Res. 4 (2004) 3108-3114
-
(2004)
Nucleic Acids Res.
, vol.4
, pp. 3108-3114
-
-
Lopez-Bigas, N.1
Ouzounis, C.A.2
-
17
-
-
0036514504
-
Modeling neurodegenerative diseases in Drosophila: a fruitful approach?
-
Muqit M.M., and Feany M.B. Modeling neurodegenerative diseases in Drosophila: a fruitful approach?. Nat. Rev. Neurosci. 3 (2002) 237-243
-
(2002)
Nat. Rev. Neurosci.
, vol.3
, pp. 237-243
-
-
Muqit, M.M.1
Feany, M.B.2
-
18
-
-
3442889367
-
OrthoDisease: a database of human disease orthologs
-
O'Brien K.P., Westerlund I., and Sonnhammer E.L. OrthoDisease: a database of human disease orthologs. Hum. Mutat. 24 (2004) 112-119
-
(2004)
Hum. Mutat.
, vol.24
, pp. 112-119
-
-
O'Brien, K.P.1
Westerlund, I.2
Sonnhammer, E.L.3
-
19
-
-
0037224073
-
Sequencing the chimpanzee genome: insights into human evolution and disease
-
Olson M.V., and Varki A. Sequencing the chimpanzee genome: insights into human evolution and disease. Nat. Rev. Genet. 4 (2003) 20-28
-
(2003)
Nat. Rev. Genet.
, vol.4
, pp. 20-28
-
-
Olson, M.V.1
Varki, A.2
-
20
-
-
26944480402
-
Beyond annotation transfer by homology:novel protein-function prediction methods to assist drug discovery
-
Ofran Y., Punta M., Schneider R., and Rost B. Beyond annotation transfer by homology:novel protein-function prediction methods to assist drug discovery. Drug Discov. Today 21 (2005) 1475-1482
-
(2005)
Drug Discov. Today
, vol.21
, pp. 1475-1482
-
-
Ofran, Y.1
Punta, M.2
Schneider, R.3
Rost, B.4
-
21
-
-
15244363491
-
The DNA sequence of the human X chromosome
-
Ross, et al. The DNA sequence of the human X chromosome. Nature 434 (2005) 325-337
-
(2005)
Nature
, vol.434
, pp. 325-337
-
-
Ross1
-
22
-
-
29144531173
-
The druggable genome: an update
-
Russ A.P., and Lampel S. The druggable genome: an update. Drug Discov. Today. 10 (2005) 1607-1610
-
(2005)
Drug Discov. Today.
, vol.10
, pp. 1607-1610
-
-
Russ, A.P.1
Lampel, S.2
-
23
-
-
1842858905
-
GeneCards 2002: towards a complete, object-oriented, human gene compendium
-
Safran M., Solomon I., Shmueli O., Lapidot M., Shen-Orr S., Adato A., et al. GeneCards 2002: towards a complete, object-oriented, human gene compendium. Bioinformatics 18 (2002) 1542-1543
-
(2002)
Bioinformatics
, vol.18
, pp. 1542-1543
-
-
Safran, M.1
Solomon, I.2
Shmueli, O.3
Lapidot, M.4
Shen-Orr, S.5
Adato, A.6
-
24
-
-
7744237366
-
Deep genomics in shallow times: the finished sequence of human chromosomes 13 and 19
-
Semple C.A. Deep genomics in shallow times: the finished sequence of human chromosomes 13 and 19. Eur. J. Hum. Genet. 12 (2004) 875-876
-
(2004)
Eur. J. Hum. Genet.
, vol.12
, pp. 875-876
-
-
Semple, C.A.1
-
25
-
-
0037903275
-
Human Gene Mutation Database (HGMD): 2003 update
-
Stenson P.D., Ball E.V., Mort M., Phillips A.D., Shiel J.A., Thomas N.S., et al. Human Gene Mutation Database (HGMD): 2003 update. Hum. Mutat. 21 (2003) 577-581
-
(2003)
Hum. Mutat.
, vol.21
, pp. 577-581
-
-
Stenson, P.D.1
Ball, E.V.2
Mort, M.3
Phillips, A.D.4
Shiel, J.A.5
Thomas, N.S.6
-
26
-
-
0042902833
-
The COG database: an updated version includes eukaryotes
-
Tatusov R.L., Fedorova N.D., Jackson J.D., Jacobs A.R., Kiryutin B., and Koonin E.V. The COG database: an updated version includes eukaryotes. BMC Bioinformatics 4 (2003) 41
-
(2003)
BMC Bioinformatics
, vol.4
, pp. 41
-
-
Tatusov, R.L.1
Fedorova, N.D.2
Jackson, J.D.3
Jacobs, A.R.4
Kiryutin, B.5
Koonin, E.V.6
-
27
-
-
0028888499
-
Response to treatment in hereditary metabolic disease: 1993 survey and 10-year comparison
-
Treacy E., Childs B., and Scriver C.R. Response to treatment in hereditary metabolic disease: 1993 survey and 10-year comparison. Am. J. Hum. Genet. 56 (1995) 359-367
-
(1995)
Am. J. Hum. Genet.
, vol.56
, pp. 359-367
-
-
Treacy, E.1
Childs, B.2
Scriver, C.R.3
-
28
-
-
33644897576
-
Further understanding human disease genes by comparing with housekeeping genes and other genes
-
Tu Z., Wang L., Xu M., Zhou X., Chen T., and Sun F. Further understanding human disease genes by comparing with housekeeping genes and other genes. BMC Genomics 7 (2006) 31
-
(2006)
BMC Genomics
, vol.7
, pp. 31
-
-
Tu, Z.1
Wang, L.2
Xu, M.3
Zhou, X.4
Chen, T.5
Sun, F.6
-
29
-
-
33644876210
-
DrugBank: a comprehensive resource for in silico drug discovery and exploration
-
Wishart D.S., Knox C., Guo A.C., Shrivastava S., Hassanali M., Stothard P., et al. DrugBank: a comprehensive resource for in silico drug discovery and exploration. Nucleic Acids Res. 34 (2006) D668-D672
-
(2006)
Nucleic Acids Res.
, vol.34
-
-
Wishart, D.S.1
Knox, C.2
Guo, A.C.3
Shrivastava, S.4
Hassanali, M.5
Stothard, P.6
-
30
-
-
0037267313
-
Knockouts model the 100 best-selling drugs-will they model the next 100?
-
Zambrowicz B.P., and Sands A.T. Knockouts model the 100 best-selling drugs-will they model the next 100?. Nat. Rev. Drug Discov. 2 (2003) 38-51
-
(2003)
Nat. Rev. Drug Discov.
, vol.2
, pp. 38-51
-
-
Zambrowicz, B.P.1
Sands, A.T.2
|