메뉴 건너뛰기




Volumn 48, Issue 4, 2008, Pages 279-296

Progress and problems in the application of focused ultrasound for blood-brain barrier disruption

Author keywords

Blood brain barrier; Brain; Drug delivery; Ultrasound

Indexed keywords

ACOUSTIC WAVES; BLOOD; BLOOD VESSELS; CHEMOTHERAPY; DRUG DELIVERY; DRUG DOSAGE; HEALTH; NEUROLOGY; PROTEINS; ULTRASONIC TRANSMISSION; ULTRASONICS;

EID: 48149101439     PISSN: 0041624X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ultras.2008.04.004     Document Type: Review
Times cited : (213)

References (211)
  • 1
    • 0036463371 scopus 로고    scopus 로고
    • Drug and gene targeting to the brain with molecular Trojan horses
    • Pardridge W.M. Drug and gene targeting to the brain with molecular Trojan horses. Nat. Rev. Drug. Discov. 1 2 (2002) 131-139
    • (2002) Nat. Rev. Drug. Discov. , vol.1 , Issue.2 , pp. 131-139
    • Pardridge, W.M.1
  • 2
    • 12344273726 scopus 로고    scopus 로고
    • The blood-brain barrier: bottleneck in brain drug development
    • Pardridge W.M. The blood-brain barrier: bottleneck in brain drug development. NeuroRx 2 1 (2005) 3-14
    • (2005) NeuroRx , vol.2 , Issue.1 , pp. 3-14
    • Pardridge, W.M.1
  • 3
    • 0042899083 scopus 로고    scopus 로고
    • Blood-brain barrier drug targeting: the future of brain drug development
    • 51
    • Pardridge W.M. Blood-brain barrier drug targeting: the future of brain drug development. Mol. Interv. 3 2 (2003) 90-105 51
    • (2003) Mol. Interv. , vol.3 , Issue.2 , pp. 90-105
    • Pardridge, W.M.1
  • 4
    • 0033518275 scopus 로고    scopus 로고
    • Designing libraries with CNS activity
    • Ajay A., Bemis G.W., and Murcko M.A. Designing libraries with CNS activity. J. Med. Chem. 42 24 (1999) 4942-4951
    • (1999) J. Med. Chem. , vol.42 , Issue.24 , pp. 4942-4951
    • Ajay, A.1    Bemis, G.W.2    Murcko, M.A.3
  • 5
    • 0032600640 scopus 로고    scopus 로고
    • A knowledge-based approach in designing combinatorial or medicinal chemistry libraries for drug discovery. 1. A qualitative and quantitative characterization of known drug databases
    • Ghose A.K., Viswanadhan V.N., and Wendoloski J.J. A knowledge-based approach in designing combinatorial or medicinal chemistry libraries for drug discovery. 1. A qualitative and quantitative characterization of known drug databases. J. Comb. Chem. 1 1 (1999) 55-68
    • (1999) J. Comb. Chem. , vol.1 , Issue.1 , pp. 55-68
    • Ghose, A.K.1    Viswanadhan, V.N.2    Wendoloski, J.J.3
  • 6
    • 0026284717 scopus 로고
    • Advances in cell biology of blood-brain barrier transport
    • Pardridge W.M. Advances in cell biology of blood-brain barrier transport. Semin. Cell. Biol. 2 6 (1991) 419-426
    • (1991) Semin. Cell. Biol. , vol.2 , Issue.6 , pp. 419-426
    • Pardridge, W.M.1
  • 7
    • 0037079071 scopus 로고    scopus 로고
    • Drug and gene delivery to the brain: the vascular route
    • Pardridge W.M. Drug and gene delivery to the brain: the vascular route. Neuron 36 4 (2002) 555-558
    • (2002) Neuron , vol.36 , Issue.4 , pp. 555-558
    • Pardridge, W.M.1
  • 10
    • 0034756894 scopus 로고    scopus 로고
    • Brain drug targeting and gene technologies
    • Pardridge W.M. Brain drug targeting and gene technologies. Jpn. J. Pharmacol. 87 2 (2001) 97-103
    • (2001) Jpn. J. Pharmacol. , vol.87 , Issue.2 , pp. 97-103
    • Pardridge, W.M.1
  • 11
    • 0029045339 scopus 로고
    • Distribution of nerve growth factor following direct delivery to brain interstitium
    • Krewson C.E., Klarman M.L., and Saltzman W.M. Distribution of nerve growth factor following direct delivery to brain interstitium. Brain Res. 680 1-2 (1995) 196-206
    • (1995) Brain Res. , vol.680 , Issue.1-2 , pp. 196-206
    • Krewson, C.E.1    Klarman, M.L.2    Saltzman, W.M.3
  • 12
    • 0029804038 scopus 로고    scopus 로고
    • Stabilization of nerve growth factor in controlled release polymers and in tissue
    • Krewson C.E., Dause R., Mak M., and Saltzman W.M. Stabilization of nerve growth factor in controlled release polymers and in tissue. J. Biomater. Sci. Polym. Ed. 8 2 (1996) 103-117
    • (1996) J. Biomater. Sci. Polym. Ed. , vol.8 , Issue.2 , pp. 103-117
    • Krewson, C.E.1    Dause, R.2    Mak, M.3    Saltzman, W.M.4
  • 13
    • 1042291304 scopus 로고    scopus 로고
    • Recent advances in brain tumor therapy: local intracerebral drug delivery by polymers
    • Guerin C., Olivi A., Weingart J.D., Lawson H.C., and Brem H. Recent advances in brain tumor therapy: local intracerebral drug delivery by polymers. Invest. New Drugs 22 1 (2004) 27-37
    • (2004) Invest. New Drugs , vol.22 , Issue.1 , pp. 27-37
    • Guerin, C.1    Olivi, A.2    Weingart, J.D.3    Lawson, H.C.4    Brem, H.5
  • 14
    • 0028289716 scopus 로고
    • Distribution of intracerebral ventricularly administered neurotrophins in rat brain and its correlation with trk receptor expression
    • Yan Q., Matheson C., Sun J., Radeke M.J., Feinstein S.C., and Miller J.A. Distribution of intracerebral ventricularly administered neurotrophins in rat brain and its correlation with trk receptor expression. Exp. Neurol. 127 1 (1994) 23-36
    • (1994) Exp. Neurol. , vol.127 , Issue.1 , pp. 23-36
    • Yan, Q.1    Matheson, C.2    Sun, J.3    Radeke, M.J.4    Feinstein, S.C.5    Miller, J.A.6
  • 16
    • 0037911432 scopus 로고    scopus 로고
    • Intraputamenal infusion of GDNF in aged rhesus monkeys: distribution and dopaminergic effects
    • Ai Y., Markesbery W., Zhang Z., Grondin R., Elseberry D., Gerhardt G.A., and Gash D.M. Intraputamenal infusion of GDNF in aged rhesus monkeys: distribution and dopaminergic effects. J. Comp. Neurol. 461 2 (2003) 250-261
    • (2003) J. Comp. Neurol. , vol.461 , Issue.2 , pp. 250-261
    • Ai, Y.1    Markesbery, W.2    Zhang, Z.3    Grondin, R.4    Elseberry, D.5    Gerhardt, G.A.6    Gash, D.M.7
  • 17
    • 13844275414 scopus 로고    scopus 로고
    • Liposome-mediated suicide gene therapy in humans
    • Reszka R.C., Jacobs A., and Voges J. Liposome-mediated suicide gene therapy in humans. Methods Enzymol. 391 (2005) 200-208
    • (2005) Methods Enzymol. , vol.391 , pp. 200-208
    • Reszka, R.C.1    Jacobs, A.2    Voges, J.3
  • 19
    • 0141732108 scopus 로고    scopus 로고
    • Intracranial delivery of proteins and peptides as a therapy for neurodegenerative diseases
    • Grondin R., Zhang Z., Ai Y., Gash D.M., and Gerhardt G.A. Intracranial delivery of proteins and peptides as a therapy for neurodegenerative diseases. Prog. Drug Res. 61 (2003) 101-123
    • (2003) Prog. Drug Res. , vol.61 , pp. 101-123
    • Grondin, R.1    Zhang, Z.2    Ai, Y.3    Gash, D.M.4    Gerhardt, G.A.5
  • 20
    • 34147138870 scopus 로고    scopus 로고
    • Convection enhanced drug delivery of novel therapeutic agents to malignant brain tumors
    • Ferguson S., and Lesniak M.S. Convection enhanced drug delivery of novel therapeutic agents to malignant brain tumors. Curr. Drug Deliv. 4 2 (2007) 169-180
    • (2007) Curr. Drug Deliv. , vol.4 , Issue.2 , pp. 169-180
    • Ferguson, S.1    Lesniak, M.S.2
  • 21
    • 0029884848 scopus 로고    scopus 로고
    • Chemotherapeutic drugs released from polymers: distribution of 1,3-bis(2-chloroethyl)-1-nitrosourea in the rat brain
    • Fung L.K., Shin M., Tyler B., Brem H., and Saltzman W.M. Chemotherapeutic drugs released from polymers: distribution of 1,3-bis(2-chloroethyl)-1-nitrosourea in the rat brain. Pharm. Res. 13 5 (1996) 671-682
    • (1996) Pharm. Res. , vol.13 , Issue.5 , pp. 671-682
    • Fung, L.K.1    Shin, M.2    Tyler, B.3    Brem, H.4    Saltzman, W.M.5
  • 24
    • 34248202633 scopus 로고    scopus 로고
    • Peptide-based immunotherapeutic approaches to glioma: a review
    • Yamanaka R., and Itoh K. Peptide-based immunotherapeutic approaches to glioma: a review. Expert Opin. Biol. Ther. 7 5 (2007) 645-649
    • (2007) Expert Opin. Biol. Ther. , vol.7 , Issue.5 , pp. 645-649
    • Yamanaka, R.1    Itoh, K.2
  • 25
    • 0035451329 scopus 로고    scopus 로고
    • Recombinant proteins for neurodegenerative diseases: the delivery issue
    • Aebischer P., and Ridet J. Recombinant proteins for neurodegenerative diseases: the delivery issue. Trends Neurosci. 24 9 (2001) 533-540
    • (2001) Trends Neurosci. , vol.24 , Issue.9 , pp. 533-540
    • Aebischer, P.1    Ridet, J.2
  • 26
    • 0021828040 scopus 로고
    • Osmotic blood-brain barrier modification: monoclonal antibody, albumin, and methotrexate delivery to cerebrospinal fluid and brain
    • Neuwelt E.A., Barnett P.A., McCormick C.I., Frenkel E.P., and Minna J.D. Osmotic blood-brain barrier modification: monoclonal antibody, albumin, and methotrexate delivery to cerebrospinal fluid and brain. Neurosurgery 17 3 (1985) 419-423
    • (1985) Neurosurgery , vol.17 , Issue.3 , pp. 419-423
    • Neuwelt, E.A.1    Barnett, P.A.2    McCormick, C.I.3    Frenkel, E.P.4    Minna, J.D.5
  • 27
    • 0034142246 scopus 로고    scopus 로고
    • Safety and efficacy of a multicenter study using intraarterial chemotherapy in conjunction with osmotic opening of the blood-brain barrier for the treatment of patients with malignant brain tumors
    • Doolittle N.D., Miner M.E., Hall W.A., Siegal T., Jerome E., Osztie E., McAllister L.D., Bubalo J.S., Kraemer D.F., Fortin D., Nixon R., Muldoon L.L., and Neuwelt E.A. Safety and efficacy of a multicenter study using intraarterial chemotherapy in conjunction with osmotic opening of the blood-brain barrier for the treatment of patients with malignant brain tumors. Cancer 88 3 (2000) 637-647
    • (2000) Cancer , vol.88 , Issue.3 , pp. 637-647
    • Doolittle, N.D.1    Miner, M.E.2    Hall, W.A.3    Siegal, T.4    Jerome, E.5    Osztie, E.6    McAllister, L.D.7    Bubalo, J.S.8    Kraemer, D.F.9    Fortin, D.10    Nixon, R.11    Muldoon, L.L.12    Neuwelt, E.A.13
  • 29
    • 0031965788 scopus 로고    scopus 로고
    • Outwitting the blood-brain barrier for therapeutic purposes: osmotic opening and other means
    • Kroll R.A., and Neuwelt E.A. Outwitting the blood-brain barrier for therapeutic purposes: osmotic opening and other means. Neurosurgery 42 5 (1998) 1083-1099
    • (1998) Neurosurgery , vol.42 , Issue.5 , pp. 1083-1099
    • Kroll, R.A.1    Neuwelt, E.A.2
  • 30
    • 0032482131 scopus 로고    scopus 로고
    • Intracarotid low dose bradykinin infusion selectively increases tumor permeability through activation of bradykinin B2 receptors in malignant gliomas
    • Matsukado K., Sugita M., and Black K.L. Intracarotid low dose bradykinin infusion selectively increases tumor permeability through activation of bradykinin B2 receptors in malignant gliomas. Brain Res. 792 1 (1998) 10-15
    • (1998) Brain Res. , vol.792 , Issue.1 , pp. 10-15
    • Matsukado, K.1    Sugita, M.2    Black, K.L.3
  • 31
    • 0020478136 scopus 로고
    • Morphologic effect of dimethyl sulfoxide on the blood-brain barrier
    • Broadwell R.D., Salcman M., and Kaplan R.S. Morphologic effect of dimethyl sulfoxide on the blood-brain barrier. Science 217 4555 (1982) 164-166
    • (1982) Science , vol.217 , Issue.4555 , pp. 164-166
    • Broadwell, R.D.1    Salcman, M.2    Kaplan, R.S.3
  • 32
    • 0030789582 scopus 로고    scopus 로고
    • Changes in the permeability of the blood-brain barrier following sodium dodecyl sulphate administration in the rat
    • Saija A., Princi P., Trombetta D., Lanza M., and De Pasquale A. Changes in the permeability of the blood-brain barrier following sodium dodecyl sulphate administration in the rat. Exp. Brain Res. 115 3 (1997) 546-551
    • (1997) Exp. Brain Res. , vol.115 , Issue.3 , pp. 546-551
    • Saija, A.1    Princi, P.2    Trombetta, D.3    Lanza, M.4    De Pasquale, A.5
  • 34
    • 0026605172 scopus 로고
    • Melphalan penetration of the blood-brain barrier via the neutral amino acid transporter in tumor-bearing brain
    • Cornford E.M., Young D., Paxton J.W., Finlay G.J., Wilson W.R., and Pardridge W.M. Melphalan penetration of the blood-brain barrier via the neutral amino acid transporter in tumor-bearing brain. Cancer Res. 52 1 (1992) 138-143
    • (1992) Cancer Res. , vol.52 , Issue.1 , pp. 138-143
    • Cornford, E.M.1    Young, D.2    Paxton, J.W.3    Finlay, G.J.4    Wilson, W.R.5    Pardridge, W.M.6
  • 35
    • 0033583924 scopus 로고    scopus 로고
    • Peripheral injections of Freund's adjuvant in mice provoke leakage of serum proteins through the blood-brain barrier without inducing reactive gliosis
    • Rabchevsky A.G., Degos J.D., and Dreyfus P.A. Peripheral injections of Freund's adjuvant in mice provoke leakage of serum proteins through the blood-brain barrier without inducing reactive gliosis. Brain Res. 832 1-2 (1999) 84-96
    • (1999) Brain Res. , vol.832 , Issue.1-2 , pp. 84-96
    • Rabchevsky, A.G.1    Degos, J.D.2    Dreyfus, P.A.3
  • 36
    • 0032543607 scopus 로고    scopus 로고
    • Loss of the tight junction proteins occludin and zonula occludens-1 from cerebral vascular endothelium during neutrophil-induced blood-brain barrier breakdown in vivo
    • Bolton S.J., Anthony D.C., and Perry V.H. Loss of the tight junction proteins occludin and zonula occludens-1 from cerebral vascular endothelium during neutrophil-induced blood-brain barrier breakdown in vivo. Neuroscience 86 4 (1998) 1245-1257
    • (1998) Neuroscience , vol.86 , Issue.4 , pp. 1245-1257
    • Bolton, S.J.1    Anthony, D.C.2    Perry, V.H.3
  • 37
    • 13144254202 scopus 로고    scopus 로고
    • CXC chemokines generate age-related increases in neutrophil-mediated brain inflammation and blood-brain barrier breakdown
    • Anthony D., Dempster R., Fearn S., Clements J., Wells G., Perry V.H., and Walker K. CXC chemokines generate age-related increases in neutrophil-mediated brain inflammation and blood-brain barrier breakdown. Curr. Biol. 8 16 (1998) 923-926
    • (1998) Curr. Biol. , vol.8 , Issue.16 , pp. 923-926
    • Anthony, D.1    Dempster, R.2    Fearn, S.3    Clements, J.4    Wells, G.5    Perry, V.H.6    Walker, K.7
  • 38
    • 0031820918 scopus 로고    scopus 로고
    • Reversible blood-brain barrier dysfunction after intracarotid hyperthermic saline infusion
    • Oztas B., and Kucuk M. Reversible blood-brain barrier dysfunction after intracarotid hyperthermic saline infusion. Int. J. Hyperthermia 14 4 (1998) 395-401
    • (1998) Int. J. Hyperthermia , vol.14 , Issue.4 , pp. 395-401
    • Oztas, B.1    Kucuk, M.2
  • 39
    • 0029055342 scopus 로고
    • Intracarotid hypothermic saline infusion: a new method for reversible blood-brain barrier disruption in anesthetized rats
    • Oztas B., and Kucuk M. Intracarotid hypothermic saline infusion: a new method for reversible blood-brain barrier disruption in anesthetized rats. Neurosci. Lett. 190 3 (1995) 203-206
    • (1995) Neurosci. Lett. , vol.190 , Issue.3 , pp. 203-206
    • Oztas, B.1    Kucuk, M.2
  • 40
    • 0028944111 scopus 로고
    • Plasma albumin is a potent trigger of calcium signals and DNA synthesis in astrocytes
    • Nadal A., Fuentes E., Pastor J., and McNaughton P.A. Plasma albumin is a potent trigger of calcium signals and DNA synthesis in astrocytes. Proc. Natl. Acad. Sci. U.S.A. 92 5 (1995) 1426-1430
    • (1995) Proc. Natl. Acad. Sci. U.S.A. , vol.92 , Issue.5 , pp. 1426-1430
    • Nadal, A.1    Fuentes, E.2    Pastor, J.3    McNaughton, P.A.4
  • 41
    • 5644276383 scopus 로고    scopus 로고
    • Delivery of bioactive molecules into the cell: the Trojan horse approach
    • Dietz G.P., and Bahr M. Delivery of bioactive molecules into the cell: the Trojan horse approach. Mol. Cell. Neurosci. 27 2 (2004) 85-131
    • (2004) Mol. Cell. Neurosci. , vol.27 , Issue.2 , pp. 85-131
    • Dietz, G.P.1    Bahr, M.2
  • 42
    • 0035937595 scopus 로고    scopus 로고
    • Nanoparticulate systems for brain delivery of drugs
    • Kreuter J. Nanoparticulate systems for brain delivery of drugs. Adv. Drug Deliv. Rev. 47 1 (2001) 65-81
    • (2001) Adv. Drug Deliv. Rev. , vol.47 , Issue.1 , pp. 65-81
    • Kreuter, J.1
  • 43
    • 3142731321 scopus 로고    scopus 로고
    • Intravenous, non-viral RNAi gene therapy of brain cancer
    • Pardridge W.M. Intravenous, non-viral RNAi gene therapy of brain cancer. Expert Opin. Biol. Ther. 4 7 (2004) 1103-1113
    • (2004) Expert Opin. Biol. Ther. , vol.4 , Issue.7 , pp. 1103-1113
    • Pardridge, W.M.1
  • 44
    • 12344251148 scopus 로고    scopus 로고
    • Tyrosine hydroxylase replacement in experimental Parkinson's disease with transvascular gene therapy
    • Pardridge W.M. Tyrosine hydroxylase replacement in experimental Parkinson's disease with transvascular gene therapy. NeuroRx 2 1 (2005) 129-138
    • (2005) NeuroRx , vol.2 , Issue.1 , pp. 129-138
    • Pardridge, W.M.1
  • 46
    • 0030447660 scopus 로고    scopus 로고
    • Brain drug delivery of small molecules using immunoliposomes
    • Huwyler J., Wu D., and Pardridge W.M. Brain drug delivery of small molecules using immunoliposomes. Proc. Natl. Acad. Sci. U.S.A. 93 24 (1996) 14164-14169
    • (1996) Proc. Natl. Acad. Sci. U.S.A. , vol.93 , Issue.24 , pp. 14164-14169
    • Huwyler, J.1    Wu, D.2    Pardridge, W.M.3
  • 47
    • 0032712180 scopus 로고    scopus 로고
    • Significant transport of doxorubicin into the brain with polysorbate 80-coated nanoparticles
    • Gulyaev A.E., Gelperina S.E., Skidan I.N., Antropov A.S., Kivman G.Y., and Kreuter J. Significant transport of doxorubicin into the brain with polysorbate 80-coated nanoparticles. Pharm. Res. 16 10 (1999) 1564-1569
    • (1999) Pharm. Res. , vol.16 , Issue.10 , pp. 1564-1569
    • Gulyaev, A.E.1    Gelperina, S.E.2    Skidan, I.N.3    Antropov, A.S.4    Kivman, G.Y.5    Kreuter, J.6
  • 48
    • 0032985063 scopus 로고    scopus 로고
    • Transferrin as a targeting ligand for liposomes and anticancer drugs
    • Singh M. Transferrin as a targeting ligand for liposomes and anticancer drugs. Curr. Pharm. Des. 5 6 (1999) 443-451
    • (1999) Curr. Pharm. Des. , vol.5 , Issue.6 , pp. 443-451
    • Singh, M.1
  • 49
    • 0028279458 scopus 로고
    • Transport of human recombinant brain-derived neurotrophic factor (BDNF) through the rat blood-brain barrier in vivo using vector-mediated peptide drug delivery
    • Pardridge W.M., Kang Y.S., and Buciak J.L. Transport of human recombinant brain-derived neurotrophic factor (BDNF) through the rat blood-brain barrier in vivo using vector-mediated peptide drug delivery. Pharm. Res. 11 5 (1994) 738-746
    • (1994) Pharm. Res. , vol.11 , Issue.5 , pp. 738-746
    • Pardridge, W.M.1    Kang, Y.S.2    Buciak, J.L.3
  • 50
    • 0033520487 scopus 로고    scopus 로고
    • In vivo protein transduction: delivery of a biologically active protein into the mouse
    • Schwarze S.R., Ho A., Vocero-Akbani A., and Dowdy S.F. In vivo protein transduction: delivery of a biologically active protein into the mouse. Science 285 5433 (1999) 1569-1572
    • (1999) Science , vol.285 , Issue.5433 , pp. 1569-1572
    • Schwarze, S.R.1    Ho, A.2    Vocero-Akbani, A.3    Dowdy, S.F.4
  • 51
    • 0033082752 scopus 로고    scopus 로고
    • Non-invasive drug delivery to the human brain using endogenous blood-brain barrier transport systems
    • Pardridge W.M. Non-invasive drug delivery to the human brain using endogenous blood-brain barrier transport systems. Pharm. Sci. Technol. Today 2 2 (1999) 49-59
    • (1999) Pharm. Sci. Technol. Today , vol.2 , Issue.2 , pp. 49-59
    • Pardridge, W.M.1
  • 52
    • 0035292828 scopus 로고    scopus 로고
    • Delivery of peptides and proteins through the blood-brain barrier
    • Bickel U., Yoshikawa T., and Pardridge W.M. Delivery of peptides and proteins through the blood-brain barrier. Adv. Drug Deliv. Rev. 46 1-3 (2001) 247-279
    • (2001) Adv. Drug Deliv. Rev. , vol.46 , Issue.1-3 , pp. 247-279
    • Bickel, U.1    Yoshikawa, T.2    Pardridge, W.M.3
  • 53
    • 0037001995 scopus 로고    scopus 로고
    • Neurotrophins, neuroprotection and the blood-brain barrier
    • Pardridge W.M. Neurotrophins, neuroprotection and the blood-brain barrier. Curr. Opin. Invest. Drugs 3 12 (2002) 1753-1757
    • (2002) Curr. Opin. Invest. Drugs , vol.3 , Issue.12 , pp. 1753-1757
    • Pardridge, W.M.1
  • 54
    • 1942506065 scopus 로고    scopus 로고
    • Gene therapy of the brain: the trans-vascular approach
    • Schlachetzki F., Zhang Y., Boado R.J., and Pardridge W.M. Gene therapy of the brain: the trans-vascular approach. Neurology 62 8 (2004) 1275-1281
    • (2004) Neurology , vol.62 , Issue.8 , pp. 1275-1281
    • Schlachetzki, F.1    Zhang, Y.2    Boado, R.J.3    Pardridge, W.M.4
  • 55
    • 33748452503 scopus 로고    scopus 로고
    • Molecular Trojan horses for blood-brain barrier drug delivery
    • Pardridge W.M. Molecular Trojan horses for blood-brain barrier drug delivery. Curr. Opin. Pharmacol. 6 5 (2006) 494-500
    • (2006) Curr. Opin. Pharmacol. , vol.6 , Issue.5 , pp. 494-500
    • Pardridge, W.M.1
  • 56
    • 12344336804 scopus 로고    scopus 로고
    • Neuroprotection in experimental stroke with targeted neurotrophins
    • Wu D. Neuroprotection in experimental stroke with targeted neurotrophins. NeuroRx 2 1 (2005) 120-128
    • (2005) NeuroRx , vol.2 , Issue.1 , pp. 120-128
    • Wu, D.1
  • 57
    • 34248550584 scopus 로고    scopus 로고
    • Molecularly targeted therapies for malignant gliomas: advances and challenges
    • Penas-Prado M., and Gilbert M.R. Molecularly targeted therapies for malignant gliomas: advances and challenges. Expert Rev. Anticancer Ther. 7 5 (2007) 641-661
    • (2007) Expert Rev. Anticancer Ther. , vol.7 , Issue.5 , pp. 641-661
    • Penas-Prado, M.1    Gilbert, M.R.2
  • 58
    • 0002851192 scopus 로고
    • Biophysics and technology of ultrasound hyperthermia
    • Gautherie M. (Ed), Springer-Verlag, New York
    • Hynynen K. Biophysics and technology of ultrasound hyperthermia. In: Gautherie M. (Ed). Methods of External Hyperthermic Heating (1990), Springer-Verlag, New York 61-115
    • (1990) Methods of External Hyperthermic Heating , pp. 61-115
    • Hynynen, K.1
  • 59
    • 0032765513 scopus 로고    scopus 로고
    • Ultrasound technology for hyperthermia
    • Diederich C.J., and Hynynen K. Ultrasound technology for hyperthermia. Ultrasound Med. Biol. 25 (1999) 871-887
    • (1999) Ultrasound Med. Biol. , vol.25 , pp. 871-887
    • Diederich, C.J.1    Hynynen, K.2
  • 60
    • 0343439560 scopus 로고
    • Principles of ultrasound used for generating localized hyperthermia
    • Field S.B., and Hand J.W. (Eds), Taylor and Francis, London
    • Hunt J.W. Principles of ultrasound used for generating localized hyperthermia. In: Field S.B., and Hand J.W. (Eds). Principle Aspects of Clinical Hyperthermia (1990), Taylor and Francis, London 371-422
    • (1990) Principle Aspects of Clinical Hyperthermia , pp. 371-422
    • Hunt, J.W.1
  • 61
    • 0003116933 scopus 로고
    • Local hyperthermia by ultrasound
    • Nussbaum G.H. (Ed), American Institute of Physics, New York
    • Lele P.P. Local hyperthermia by ultrasound. In: Nussbaum G.H. (Ed). Physical Aspects of Hyperthermia (1982), American Institute of Physics, New York 393-440
    • (1982) Physical Aspects of Hyperthermia , pp. 393-440
    • Lele, P.P.1
  • 62
    • 48149099182 scopus 로고    scopus 로고
    • K. Hynynen, G. Clement, N. McDannold, R. King, P.J. White, F. Jolesz, S. Vitek, E. Zadicario, Pre-clinical testing of a phased array ultrasound system for MRI-guided noninvasive surgery of the brain, in: Proceedings of the Eleventh Meeting of the International Society for Magnetic Resonance in Medicine, Toronto, ON, 2003, p. 77.
    • K. Hynynen, G. Clement, N. McDannold, R. King, P.J. White, F. Jolesz, S. Vitek, E. Zadicario, Pre-clinical testing of a phased array ultrasound system for MRI-guided noninvasive surgery of the brain, in: Proceedings of the Eleventh Meeting of the International Society for Magnetic Resonance in Medicine, Toronto, ON, 2003, p. 77.
  • 63
    • 0036852570 scopus 로고    scopus 로고
    • An image-guided high intensity focused ultrasound device for uterine fibroids treatment
    • Chan A.H., Fujimoto V.Y., Moore D.E., Martin R.W., and Vaezy S. An image-guided high intensity focused ultrasound device for uterine fibroids treatment. Med. Phys. 29 11 (2002) 2611-2620
    • (2002) Med. Phys. , vol.29 , Issue.11 , pp. 2611-2620
    • Chan, A.H.1    Fujimoto, V.Y.2    Moore, D.E.3    Martin, R.W.4    Vaezy, S.5
  • 64
    • 0032964032 scopus 로고    scopus 로고
    • Treatment of localised prostate cancer with transrectal high intensity focused ultrasound
    • Chapelon J.Y., Ribault M., Vernier F., Souchon R., and Gelet A. Treatment of localised prostate cancer with transrectal high intensity focused ultrasound. Eur. J. Ultrasound 9 1 (1999) 31-38
    • (1999) Eur. J. Ultrasound , vol.9 , Issue.1 , pp. 31-38
    • Chapelon, J.Y.1    Ribault, M.2    Vernier, F.3    Souchon, R.4    Gelet, A.5
  • 65
    • 0037665890 scopus 로고    scopus 로고
    • High intensity focused ultrasound in the treatment of primary malignant bone tumor
    • Chen W., Wang Z., Wu F., Zhu H., Zou J., Bai J., Li K., and Xie F. High intensity focused ultrasound in the treatment of primary malignant bone tumor. Zhonghua Zhong Liu Za Zhi 24 6 (2002) 612-615
    • (2002) Zhonghua Zhong Liu Za Zhi , vol.24 , Issue.6 , pp. 612-615
    • Chen, W.1    Wang, Z.2    Wu, F.3    Zhu, H.4    Zou, J.5    Bai, J.6    Li, K.7    Xie, F.8
  • 66
    • 1842789826 scopus 로고    scopus 로고
    • Local recurrence of prostate cancer after external beam radiotherapy: early experience of salvage therapy using high-intensity focused ultrasonography
    • Gelet A., Chapelon J.Y., Poissonnier L., Bouvier R., Rouviere O., Curiel L., Janier M., and Vallancien G. Local recurrence of prostate cancer after external beam radiotherapy: early experience of salvage therapy using high-intensity focused ultrasonography. Urology 63 4 (2004) 625-629
    • (2004) Urology , vol.63 , Issue.4 , pp. 625-629
    • Gelet, A.1    Chapelon, J.Y.2    Poissonnier, L.3    Bouvier, R.4    Rouviere, O.5    Curiel, L.6    Janier, M.7    Vallancien, G.8
  • 67
    • 0842287225 scopus 로고    scopus 로고
    • A randomised clinical trial of high-intensity focused ultrasound ablation for the treatment of patients with localised breast cancer
    • Wu F., Wang Z.B., Cao Y.D., Chen W.Z., Bai J., Zou J.Z., and Zhu H. A randomised clinical trial of high-intensity focused ultrasound ablation for the treatment of patients with localised breast cancer. Br. J. Cancer 89 12 (2003) 2227-2233
    • (2003) Br. J. Cancer , vol.89 , Issue.12 , pp. 2227-2233
    • Wu, F.1    Wang, Z.B.2    Cao, Y.D.3    Chen, W.Z.4    Bai, J.5    Zou, J.Z.6    Zhu, H.7
  • 68
    • 0345688804 scopus 로고    scopus 로고
    • MR imaging-guided focused ultrasound surgery of breast cancer: correlation of dynamic contrast-enhanced MRI with histopathologic findings
    • Gianfelice D., Khiat A., Amara M., Belblidia A., and Boulanger Y. MR imaging-guided focused ultrasound surgery of breast cancer: correlation of dynamic contrast-enhanced MRI with histopathologic findings. Breast Cancer Res. Treat. 82 2 (2003) 93-101
    • (2003) Breast Cancer Res. Treat. , vol.82 , Issue.2 , pp. 93-101
    • Gianfelice, D.1    Khiat, A.2    Amara, M.3    Belblidia, A.4    Boulanger, Y.5
  • 69
    • 0036093264 scopus 로고    scopus 로고
    • High intensity focused ultrasound as noninvasive therapy for multilocal renal cell carcinoma: case study and review of the literature
    • Kohrmann K.U., Michel M.S., Gaa J., Marlinghaus E., and Alken P. High intensity focused ultrasound as noninvasive therapy for multilocal renal cell carcinoma: case study and review of the literature. J. Urol. 167 6 (2002) 2397-2403
    • (2002) J. Urol. , vol.167 , Issue.6 , pp. 2397-2403
    • Kohrmann, K.U.1    Michel, M.S.2    Gaa, J.3    Marlinghaus, E.4    Alken, P.5
  • 70
    • 0037372845 scopus 로고    scopus 로고
    • MR imaging-guided focused ultrasound surgery of uterine leiomyomas: a feasibility study
    • Tempany C.M., Stewart E.A., McDannold N., Quade B.J., Jolesz F.A., and Hynynen K. MR imaging-guided focused ultrasound surgery of uterine leiomyomas: a feasibility study. Radiology 226 3 (2003) 897-905
    • (2003) Radiology , vol.226 , Issue.3 , pp. 897-905
    • Tempany, C.M.1    Stewart, E.A.2    McDannold, N.3    Quade, B.J.4    Jolesz, F.A.5    Hynynen, K.6
  • 71
    • 0034949394 scopus 로고    scopus 로고
    • High intensity focused ultrasound for the treatment of tumors
    • ter Haar G.R. High intensity focused ultrasound for the treatment of tumors. Echocardiography 18 4 (2001) 317-322
    • (2001) Echocardiography , vol.18 , Issue.4 , pp. 317-322
    • ter Haar, G.R.1
  • 72
    • 16644364409 scopus 로고    scopus 로고
    • Extracorporeal high intensity focused ultrasound ablation in the treatment of patients with large hepatocellular carcinoma
    • Wu F., Wang Z.B., Chen W.Z., Zhu H., Bai J., Zou J.Z., Li K.Q., Jin C.B., Xie F.L., and Su H.B. Extracorporeal high intensity focused ultrasound ablation in the treatment of patients with large hepatocellular carcinoma. Ann. Surg. Oncol. 11 12 (2004) 1061-1069
    • (2004) Ann. Surg. Oncol. , vol.11 , Issue.12 , pp. 1061-1069
    • Wu, F.1    Wang, Z.B.2    Chen, W.Z.3    Zhu, H.4    Bai, J.5    Zou, J.Z.6    Li, K.Q.7    Jin, C.B.8    Xie, F.L.9    Su, H.B.10
  • 76
    • 0034955195 scopus 로고    scopus 로고
    • High intensity focused ultrasound: a method of hemostasis
    • Vaezy S., Martin R., and Crum L. High intensity focused ultrasound: a method of hemostasis. Echocardiography 18 4 (2001) 309-315
    • (2001) Echocardiography , vol.18 , Issue.4 , pp. 309-315
    • Vaezy, S.1    Martin, R.2    Crum, L.3
  • 77
    • 0030473798 scopus 로고    scopus 로고
    • Noninvasive arterial occlusion using MRI-guided focused ultrasound
    • Hynynen K., Colucci V., Chung A., and Jolesz F. Noninvasive arterial occlusion using MRI-guided focused ultrasound. Ultrasound Med. Biol. 22 8 (1996) 1071-1077
    • (1996) Ultrasound Med. Biol. , vol.22 , Issue.8 , pp. 1071-1077
    • Hynynen, K.1    Colucci, V.2    Chung, A.3    Jolesz, F.4
  • 79
    • 0033310767 scopus 로고    scopus 로고
    • K. Hynynen, J. Sun, G. Clement, J. Thierman, D. Daum, N. I. Vykhodtseva, N.J. McDannold, Phased array development for noninvasive focused ultrasound therapy of brain and liver, in: Proceedings of the First Joint BMES/EMBS Conference, 1999, p. 1270.
    • K. Hynynen, J. Sun, G. Clement, J. Thierman, D. Daum, N. I. Vykhodtseva, N.J. McDannold, Phased array development for noninvasive focused ultrasound therapy of brain and liver, in: Proceedings of the First Joint BMES/EMBS Conference, 1999, p. 1270.
  • 80
    • 0032005450 scopus 로고    scopus 로고
    • Demonstration of potential noninvasive ultrasound brain therapy through an intact skull
    • Hynynen K., and Jolesz F.A. Demonstration of potential noninvasive ultrasound brain therapy through an intact skull. Ultrasound Med. Biol. 24 2 (1998) 275-283
    • (1998) Ultrasound Med. Biol. , vol.24 , Issue.2 , pp. 275-283
    • Hynynen, K.1    Jolesz, F.A.2
  • 81
    • 0033044247 scopus 로고    scopus 로고
    • The potential of transskull ultrasound therapy and surgery using the maximum available skull surface area
    • Sun J., and Hynynen K. The potential of transskull ultrasound therapy and surgery using the maximum available skull surface area. J. Acoust. Soc. Am. 105 4 (1999) 2519-2527
    • (1999) J. Acoust. Soc. Am. , vol.105 , Issue.4 , pp. 2519-2527
    • Sun, J.1    Hynynen, K.2
  • 82
    • 0037149993 scopus 로고    scopus 로고
    • A non-invasive method for focusing ultrasound through the human skull
    • Clement G.T., and Hynynen K. A non-invasive method for focusing ultrasound through the human skull. Phys. Med. Biol. 47 8 (2002) 1219-1236
    • (2002) Phys. Med. Biol. , vol.47 , Issue.8 , pp. 1219-1236
    • Clement, G.T.1    Hynynen, K.2
  • 83
    • 0031694165 scopus 로고    scopus 로고
    • Focusing of therapeutic ultrasound through a human skull: a numerical study
    • Sun J., and Hynynen K. Focusing of therapeutic ultrasound through a human skull: a numerical study. J. Acoust. Soc. Am. 104 3 Pt 1 (1998) 1705-1715
    • (1998) J. Acoust. Soc. Am. , vol.104 , Issue.3 PART 1 , pp. 1705-1715
    • Sun, J.1    Hynynen, K.2
  • 84
    • 0041411671 scopus 로고    scopus 로고
    • High power transcranial beam steering for ultrasonic brain therapy
    • Pernot M., Aubry J.F., Tanter M., Thomas J.L., and Fink M. High power transcranial beam steering for ultrasonic brain therapy. Phys. Med. Biol. 48 16 (2003) 2577-2589
    • (2003) Phys. Med. Biol. , vol.48 , Issue.16 , pp. 2577-2589
    • Pernot, M.1    Aubry, J.F.2    Tanter, M.3    Thomas, J.L.4    Fink, M.5
  • 85
    • 0037237319 scopus 로고    scopus 로고
    • Experimental demonstration of noninvasive transskull adaptive focusing based on prior computed tomography scans
    • Aubry J.F., Tanter M., Pernot M., Thomas J.L., and Fink M. Experimental demonstration of noninvasive transskull adaptive focusing based on prior computed tomography scans. J. Acoust. Soc. Am. 113 1 (2003) 84-93
    • (2003) J. Acoust. Soc. Am. , vol.113 , Issue.1 , pp. 84-93
    • Aubry, J.F.1    Tanter, M.2    Pernot, M.3    Thomas, J.L.4    Fink, M.5
  • 86
    • 22844452715 scopus 로고    scopus 로고
    • A numerical study of transcranial focused ultrasound beam propagation at low frequency
    • Yin X., and Hynynen K. A numerical study of transcranial focused ultrasound beam propagation at low frequency. Phys. Med. Biol. 50 8 (2005) 1821-1836
    • (2005) Phys. Med. Biol. , vol.50 , Issue.8 , pp. 1821-1836
    • Yin, X.1    Hynynen, K.2
  • 87
    • 48149104666 scopus 로고    scopus 로고
    • The feasibility of noninvasive image-guided treatments of brain disodereds by focused ultrasound
    • Hynynen K., Clement G., McDannold N., and Vykhodtseva N. The feasibility of noninvasive image-guided treatments of brain disodereds by focused ultrasound. J. Acoust. Soc. Am. 115 5 (2004) 2446
    • (2004) J. Acoust. Soc. Am. , vol.115 , Issue.5 , pp. 2446
    • Hynynen, K.1    Clement, G.2    McDannold, N.3    Vykhodtseva, N.4
  • 88
    • 4644312297 scopus 로고    scopus 로고
    • 500-Element ultrasound phased array system for noninvasive focal surgery of the brain: a preliminary rabbit study with ex vivo human skulls
    • Hynynen K., Clement G.T., McDannold N., Vykhodtseva N., King R., White P.J., Vitek S., and Jolesz F.A. 500-Element ultrasound phased array system for noninvasive focal surgery of the brain: a preliminary rabbit study with ex vivo human skulls. Magn. Reson. Med. 52 1 (2004) 100-107
    • (2004) Magn. Reson. Med. , vol.52 , Issue.1 , pp. 100-107
    • Hynynen, K.1    Clement, G.T.2    McDannold, N.3    Vykhodtseva, N.4    King, R.5    White, P.J.6    Vitek, S.7    Jolesz, F.A.8
  • 89
    • 0342688501 scopus 로고
    • Effects of high intensity ultrasound on the central nervous system of the cat
    • Barnard J.W., Fry W.J., Fry F.J., and Krumins R.F. Effects of high intensity ultrasound on the central nervous system of the cat. J. Comp. Neurol. 103 3 (1955) 459-484
    • (1955) J. Comp. Neurol. , vol.103 , Issue.3 , pp. 459-484
    • Barnard, J.W.1    Fry, W.J.2    Fry, F.J.3    Krumins, R.F.4
  • 91
    • 0001443488 scopus 로고
    • Progress and problems in the neurological applications of focused ultrasound
    • Ballantine Jr. H.T., Bell E., and Manlapaz J. Progress and problems in the neurological applications of focused ultrasound. J. Neurosurg. 17 (1960) 858-876
    • (1960) J. Neurosurg. , vol.17 , pp. 858-876
    • Ballantine Jr., H.T.1    Bell, E.2    Manlapaz, J.3
  • 92
    • 0000834425 scopus 로고
    • An experimental neuropathological study of the effects of high-frequency focused ultrasound on the brain of the cat
    • Astrom K.E., Bell Ballantine Jr. H.T., and Heidensleben E. An experimental neuropathological study of the effects of high-frequency focused ultrasound on the brain of the cat. J. Neuropathol. Exp. Neurol. 20 (1961) 484-520
    • (1961) J. Neuropathol. Exp. Neurol. , vol.20 , pp. 484-520
    • Astrom, K.E.1    Bell Ballantine Jr., H.T.2    Heidensleben, E.3
  • 93
    • 0001723248 scopus 로고
    • A simple method for production of trackless focal lesions with focused ultrasound: statistical evaluation of the effects of irradiation on the central nervous system of the cat
    • Basauri L., and Lele P.P. A simple method for production of trackless focal lesions with focused ultrasound: statistical evaluation of the effects of irradiation on the central nervous system of the cat. J. Physiol. 160 3 (1962) 513-534
    • (1962) J. Physiol. , vol.160 , Issue.3 , pp. 513-534
    • Basauri, L.1    Lele, P.P.2
  • 94
    • 0014261697 scopus 로고
    • Trackless lesions in nervous tissues produced by high intensity focused ultrasound (high-frequency mechanical waves)
    • Warwick R., and Pond J. Trackless lesions in nervous tissues produced by high intensity focused ultrasound (high-frequency mechanical waves). J. Anat. 102 3 (1968) 387-405
    • (1968) J. Anat. , vol.102 , Issue.3 , pp. 387-405
    • Warwick, R.1    Pond, J.2
  • 95
    • 0017099058 scopus 로고
    • [Use of focused ultrasound for local destruction of different brain structures] Primenenie fokusirovannogo ul'trazvuka dlia lokal'nykh razrushenii razlichnykh struktur golovnogo mozga
    • Vykhodtseva N.I., Gavrilov L.R., Mering T.A., and Iamshchikova N.G. [Use of focused ultrasound for local destruction of different brain structures] Primenenie fokusirovannogo ul'trazvuka dlia lokal'nykh razrushenii razlichnykh struktur golovnogo mozga. Zh. Nevropatol. Psikhiatr. 76 12 (1976) 1810-1816
    • (1976) Zh. Nevropatol. Psikhiatr. , vol.76 , Issue.12 , pp. 1810-1816
    • Vykhodtseva, N.I.1    Gavrilov, L.R.2    Mering, T.A.3    Iamshchikova, N.G.4
  • 96
    • 48149113717 scopus 로고    scopus 로고
    • N. Vykhodtseva, Effects of high intensity pulsed ultrasound on brain tissues, in: Proceedings of the 5th International Symposium on Ultrasound in Biol. Med., Puschino, Russia, 1981, pp. 95-97.
    • N. Vykhodtseva, Effects of high intensity pulsed ultrasound on brain tissues, in: Proceedings of the 5th International Symposium on Ultrasound in Biol. Med., Puschino, Russia, 1981, pp. 95-97.
  • 97
    • 0034876083 scopus 로고    scopus 로고
    • Noninvasive MR imaging-guided focal opening of the blood-brain barrier in rabbits
    • Hynynen K., McDannold N., Vykhodtseva N., and Jolesz F.A. Noninvasive MR imaging-guided focal opening of the blood-brain barrier in rabbits. Radiology 220 3 (2001) 640-646
    • (2001) Radiology , vol.220 , Issue.3 , pp. 640-646
    • Hynynen, K.1    McDannold, N.2    Vykhodtseva, N.3    Jolesz, F.A.4
  • 98
    • 0037361542 scopus 로고    scopus 로고
    • The threshold for brain damage in rabbits induced by bursts of ultrasound in the presence of an ultrasound contrast agent (Optison)
    • Hynynen K., McDannold N., Martin H., Jolesz F.A., and Vykhodtseva N. The threshold for brain damage in rabbits induced by bursts of ultrasound in the presence of an ultrasound contrast agent (Optison). Ultrasound Med. Biol. 29 3 (2003) 473-481
    • (2003) Ultrasound Med. Biol. , vol.29 , Issue.3 , pp. 473-481
    • Hynynen, K.1    McDannold, N.2    Martin, H.3    Jolesz, F.A.4    Vykhodtseva, N.5
  • 100
    • 10044278240 scopus 로고    scopus 로고
    • Local and reversible blood-brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonications
    • Hynynen K., McDannold N., Sheikov N.A., Jolesz F.A., and Vykhodtseva N. Local and reversible blood-brain barrier disruption by noninvasive focused ultrasound at frequencies suitable for trans-skull sonications. Neuroimage 24 1 (2005) 12-20
    • (2005) Neuroimage , vol.24 , Issue.1 , pp. 12-20
    • Hynynen, K.1    McDannold, N.2    Sheikov, N.A.3    Jolesz, F.A.4    Vykhodtseva, N.5
  • 101
    • 33748483260 scopus 로고    scopus 로고
    • Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery
    • Hynynen K., McDannold N., Vykhodtseva N., Raymond S., Weissleder R., Jolesz F.A., and Sheikov N. Focal disruption of the blood-brain barrier due to 260-kHz ultrasound bursts: a method for molecular imaging and targeted drug delivery. J. Neurosurg. 105 3 (2006) 445-454
    • (2006) J. Neurosurg. , vol.105 , Issue.3 , pp. 445-454
    • Hynynen, K.1    McDannold, N.2    Vykhodtseva, N.3    Raymond, S.4    Weissleder, R.5    Jolesz, F.A.6    Sheikov, N.7
  • 103
    • 0029148503 scopus 로고
    • Histologic effects of high intensity pulsed ultrasound exposure with subharmonic emission in rabbit brain in vivo
    • Vykhodtseva N.I., Hynynen K., and Damianou C. Histologic effects of high intensity pulsed ultrasound exposure with subharmonic emission in rabbit brain in vivo. Ultrasound Med. Biol. 21 7 (1995) 969-979
    • (1995) Ultrasound Med. Biol. , vol.21 , Issue.7 , pp. 969-979
    • Vykhodtseva, N.I.1    Hynynen, K.2    Damianou, C.3
  • 106
    • 48149111611 scopus 로고    scopus 로고
    • N. Vykhodtseva, N. McDannold, S. Agabian, K. Hynynen, Histology findings after ultrasound exposure of the brain with ultrasound contrast agent - role of ischemia and apoptosis, in: Proceedings of the Third International Symposium on Therapeutic Ultrasound, 22-25 June, Lyon, France, 2003, pp. 80-85.
    • N. Vykhodtseva, N. McDannold, S. Agabian, K. Hynynen, Histology findings after ultrasound exposure of the brain with ultrasound contrast agent - role of ischemia and apoptosis, in: Proceedings of the Third International Symposium on Therapeutic Ultrasound, 22-25 June, Lyon, France, 2003, pp. 80-85.
  • 107
    • 27744441243 scopus 로고    scopus 로고
    • MRI-guided targeted blood-brain barrier disruption with focused ultrasound: histological findings in rabbits
    • McDannold N., Vykhodtseva N., Raymond S., Jolesz F.A., and Hynynen K. MRI-guided targeted blood-brain barrier disruption with focused ultrasound: histological findings in rabbits. Ultrasound Med. Biol. 31 11 (2005) 1527-1537
    • (2005) Ultrasound Med. Biol. , vol.31 , Issue.11 , pp. 1527-1537
    • McDannold, N.1    Vykhodtseva, N.2    Raymond, S.3    Jolesz, F.A.4    Hynynen, K.5
  • 108
    • 42949140276 scopus 로고    scopus 로고
    • Blood-brain barrier disruption induced by focused ultrasound and circulating preformed microbubbles appears to be characterized by the mechanical index
    • McDannold N., Vykhodtseva N., and Hynynen K. Blood-brain barrier disruption induced by focused ultrasound and circulating preformed microbubbles appears to be characterized by the mechanical index. Ultrasound Med. Biol. 34 (2008) 834-840
    • (2008) Ultrasound Med. Biol. , vol.34 , pp. 834-840
    • McDannold, N.1    Vykhodtseva, N.2    Hynynen, K.3
  • 109
    • 33645513645 scopus 로고    scopus 로고
    • Targeted disruption of the blood-brain barrier with focused ultrasound: association with cavitation activity
    • McDannold N., Vykhodtseva N., and Hynynen K. Targeted disruption of the blood-brain barrier with focused ultrasound: association with cavitation activity. Phys. Med. Biol. 51 4 (2006) 793-807
    • (2006) Phys. Med. Biol. , vol.51 , Issue.4 , pp. 793-807
    • McDannold, N.1    Vykhodtseva, N.2    Hynynen, K.3
  • 110
    • 33947524046 scopus 로고    scopus 로고
    • Use of ultrasound pulses combined with definity for targeted blood-brain barrier disruption: a feasibility study
    • McDannold N., Vykhodtseva N., and Hynynen K. Use of ultrasound pulses combined with definity for targeted blood-brain barrier disruption: a feasibility study. Ultrasound Med. Biol. 33 4 (2007) 584-590
    • (2007) Ultrasound Med. Biol. , vol.33 , Issue.4 , pp. 584-590
    • McDannold, N.1    Vykhodtseva, N.2    Hynynen, K.3
  • 111
    • 34547121440 scopus 로고    scopus 로고
    • Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI-guided focused ultrasound
    • Treat L.H., McDannold N., Vykhodtseva N., Zhang Y., Tam K., and Hynynen K. Targeted delivery of doxorubicin to the rat brain at therapeutic levels using MRI-guided focused ultrasound. Int. J. Cancer 121 4 (2007) 901-907
    • (2007) Int. J. Cancer , vol.121 , Issue.4 , pp. 901-907
    • Treat, L.H.1    McDannold, N.2    Vykhodtseva, N.3    Zhang, Y.4    Tam, K.5    Hynynen, K.6
  • 112
    • 43849110904 scopus 로고    scopus 로고
    • N. McDannold, N. Vykhodtseva, K. Hynynen, Effects of acoustic parameters and ultrasound contrast agent dose on focused-ultrasound induced blood-brain barrier disruption, Ultrasound Med. Biol. (2008), in press.
    • N. McDannold, N. Vykhodtseva, K. Hynynen, Effects of acoustic parameters and ultrasound contrast agent dose on focused-ultrasound induced blood-brain barrier disruption, Ultrasound Med. Biol. (2008), in press.
  • 113
    • 48149108507 scopus 로고    scopus 로고
    • K. Hynynen, N. McDannold, L. Josphson, N. Vykhodtseva, R. Weisleder, F.A. Jolesz, Noninvasive MRI-guided focal opening of the blood brain barrier: demonstration of large particle penetration, in: Proceedings of the Tenth Meeting of the International Society for Magnetic Resonance in Medicine, Honolulu, HI, 2002, p. 332.
    • K. Hynynen, N. McDannold, L. Josphson, N. Vykhodtseva, R. Weisleder, F.A. Jolesz, Noninvasive MRI-guided focal opening of the blood brain barrier: demonstration of large particle penetration, in: Proceedings of the Tenth Meeting of the International Society for Magnetic Resonance in Medicine, Honolulu, HI, 2002, p. 332.
  • 114
    • 33746851261 scopus 로고    scopus 로고
    • Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption
    • Kinoshita M., McDannold N., Jolesz F.A., and Hynynen K. Noninvasive localized delivery of Herceptin to the mouse brain by MRI-guided focused ultrasound-induced blood-brain barrier disruption. Proc. Natl. Acad. Sci. U.S.A. 103 31 (2006) 11719-11723
    • (2006) Proc. Natl. Acad. Sci. U.S.A. , vol.103 , Issue.31 , pp. 11719-11723
    • Kinoshita, M.1    McDannold, N.2    Jolesz, F.A.3    Hynynen, K.4
  • 115
    • 0016756272 scopus 로고
    • Continuous cultures of fused cells secreting antibody of predefined specificity
    • Kohler G., and Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. Nature 256 5517 (1975) 495-497
    • (1975) Nature , vol.256 , Issue.5517 , pp. 495-497
    • Kohler, G.1    Milstein, C.2
  • 116
    • 0642277762 scopus 로고    scopus 로고
    • Monoclonal antibodies in the treatment of cancer, Part 1
    • Cersosimo R.J. Monoclonal antibodies in the treatment of cancer, Part 1. Am. J. Health Syst. Pharm. 60 15 (2003) 1531-1548
    • (2003) Am. J. Health Syst. Pharm. , vol.60 , Issue.15 , pp. 1531-1548
    • Cersosimo, R.J.1
  • 117
    • 2142714017 scopus 로고    scopus 로고
    • Monoclonal antibodies as therapeutic agents for cancer
    • Harris M. Monoclonal antibodies as therapeutic agents for cancer. Lancet Oncol. 5 5 (2004) 292-302
    • (2004) Lancet Oncol. , vol.5 , Issue.5 , pp. 292-302
    • Harris, M.1
  • 118
    • 16844385150 scopus 로고    scopus 로고
    • Continuous cultures of fused cells secreting antibody of predefined specificity
    • (1975)
    • Kohler G., and Milstein C. Continuous cultures of fused cells secreting antibody of predefined specificity. J. Immunol. 174 5 (2005) 2453-2455 (1975)
    • (2005) J. Immunol. , vol.174 , Issue.5 , pp. 2453-2455
    • Kohler, G.1    Milstein, C.2
  • 119
    • 34147150749 scopus 로고    scopus 로고
    • Emerging monoclonal antibody therapies for malignant gliomas
    • Gerber D.E., and Laterra J. Emerging monoclonal antibody therapies for malignant gliomas. Expert Opin. Invest. Drugs 16 4 (2007) 477-494
    • (2007) Expert Opin. Invest. Drugs , vol.16 , Issue.4 , pp. 477-494
    • Gerber, D.E.1    Laterra, J.2
  • 120
    • 4043180004 scopus 로고    scopus 로고
    • The promise of targeted therapy: cancer drugs become more specific
    • Segota E., and Bukowski R.M. The promise of targeted therapy: cancer drugs become more specific. Cleve Clin. J. Med. 71 7 (2004) 551-560
    • (2004) Cleve Clin. J. Med. , vol.71 , Issue.7 , pp. 551-560
    • Segota, E.1    Bukowski, R.M.2
  • 122
    • 14844343723 scopus 로고    scopus 로고
    • Perspectives on cancer therapy with radiolabeled monoclonal antibodies
    • Sharkey R.M., and Goldenberg D.M. Perspectives on cancer therapy with radiolabeled monoclonal antibodies. J. Nucl. Med. 46 Suppl. 1 (2005) 115S-127S
    • (2005) J. Nucl. Med. , vol.46 , Issue.SUPPL. 1
    • Sharkey, R.M.1    Goldenberg, D.M.2
  • 123
    • 14844341937 scopus 로고    scopus 로고
    • Current status of therapy of solid tumors: brain tumor therapy
    • Zalutsky M.R. Current status of therapy of solid tumors: brain tumor therapy. J. Nucl. Med. 46 Suppl. 1 (2005) 151S-156S
    • (2005) J. Nucl. Med. , vol.46 , Issue.SUPPL. 1
    • Zalutsky, M.R.1
  • 126
    • 3242777026 scopus 로고    scopus 로고
    • Modulation of the blood-brain barrier in oncology: therapeutic opportunities for the treatment of brain tumours?
    • Kemper E.M., Boogerd W., Thuis I., Beijnen J.H., and van Tellingen O. Modulation of the blood-brain barrier in oncology: therapeutic opportunities for the treatment of brain tumours?. Cancer Treat. Rev. 30 5 (2004) 415-423
    • (2004) Cancer Treat. Rev. , vol.30 , Issue.5 , pp. 415-423
    • Kemper, E.M.1    Boogerd, W.2    Thuis, I.3    Beijnen, J.H.4    van Tellingen, O.5
  • 128
    • 0023212694 scopus 로고
    • Increased delivery of tumor-specific monoclonal antibodies to brain after osmotic blood-brain barrier modification in patients with melanoma metastatic to the central nervous system
    • Neuwelt E.A., Specht H.D., Barnett P.A., Dahlborg S.A., Miley A., Larson S.M., Brown P., Eckerman K.F., Hellstrom K.E., and Hellstrom I. Increased delivery of tumor-specific monoclonal antibodies to brain after osmotic blood-brain barrier modification in patients with melanoma metastatic to the central nervous system. Neurosurgery 20 6 (1987) 885-895
    • (1987) Neurosurgery , vol.20 , Issue.6 , pp. 885-895
    • Neuwelt, E.A.1    Specht, H.D.2    Barnett, P.A.3    Dahlborg, S.A.4    Miley, A.5    Larson, S.M.6    Brown, P.7    Eckerman, K.F.8    Hellstrom, K.E.9    Hellstrom, I.10
  • 130
    • 3242759188 scopus 로고    scopus 로고
    • Osmotic blood-brain barrier modification for the treatment of malignant brain tumors
    • Haluska M., and Anthony M.L. Osmotic blood-brain barrier modification for the treatment of malignant brain tumors. Clin. J. Oncol. Nurs. 8 3 (2004) 263-267
    • (2004) Clin. J. Oncol. Nurs. , vol.8 , Issue.3 , pp. 263-267
    • Haluska, M.1    Anthony, M.L.2
  • 131
    • 30544447180 scopus 로고    scopus 로고
    • Targeted delivery of antibodies through the blood-brain barrier by MRI-guided focused ultrasound
    • Kinoshita M., McDannold N., Jolesz F.A., and Hynynen K. Targeted delivery of antibodies through the blood-brain barrier by MRI-guided focused ultrasound. Biochem. Biophys. Res. Commun. 340 4 (2006) 1085-1090
    • (2006) Biochem. Biophys. Res. Commun. , vol.340 , Issue.4 , pp. 1085-1090
    • Kinoshita, M.1    McDannold, N.2    Jolesz, F.A.3    Hynynen, K.4
  • 134
    • 1242311596 scopus 로고    scopus 로고
    • What can we learn from Herceptin trials in metastatic breast cancer?
    • Bell R. What can we learn from Herceptin trials in metastatic breast cancer?. Oncology 63 Suppl. 1 (2002) 39-46
    • (2002) Oncology , vol.63 , Issue.SUPPL. 1 , pp. 39-46
    • Bell, R.1
  • 136
    • 0036976431 scopus 로고    scopus 로고
    • Chemotherapy for breast cancer brain metastases
    • Fenner M.H., and Possinger K. Chemotherapy for breast cancer brain metastases. Onkologie 25 5 (2002) 474-479
    • (2002) Onkologie , vol.25 , Issue.5 , pp. 474-479
    • Fenner, M.H.1    Possinger, K.2
  • 138
    • 27744440126 scopus 로고    scopus 로고
    • Isolated central nervous system metastases in patients with HER2-overexpressing advanced breast cancer treated with first-line trastuzumab-based therapy
    • Burstein H.J., Lieberman G., Slamon D.J., Winer E.P., and Klein P. Isolated central nervous system metastases in patients with HER2-overexpressing advanced breast cancer treated with first-line trastuzumab-based therapy. Ann. Oncol. 16 11 (2005) 1772-1777
    • (2005) Ann. Oncol. , vol.16 , Issue.11 , pp. 1772-1777
    • Burstein, H.J.1    Lieberman, G.2    Slamon, D.J.3    Winer, E.P.4    Klein, P.5
  • 139
    • 0041696795 scopus 로고    scopus 로고
    • Increased rate of brain metastasis with trastuzumab therapy not associated with impaired survival
    • Lower E.E., Drosick D.R., Blau R., Brennan L., Danneman W., and Hawley D.K. Increased rate of brain metastasis with trastuzumab therapy not associated with impaired survival. Clin. Breast Cancer 4 2 (2003) 114-119
    • (2003) Clin. Breast Cancer , vol.4 , Issue.2 , pp. 114-119
    • Lower, E.E.1    Drosick, D.R.2    Blau, R.3    Brennan, L.4    Danneman, W.5    Hawley, D.K.6
  • 140
    • 33847096349 scopus 로고    scopus 로고
    • Doxorubicin-induced cardiomyopathy from the cardiotoxic mechanisms to management
    • Takemura G., and Fujiwara H. Doxorubicin-induced cardiomyopathy from the cardiotoxic mechanisms to management. Prog. Cardiovasc. Dis. 49 5 (2007) 330-352
    • (2007) Prog. Cardiovasc. Dis. , vol.49 , Issue.5 , pp. 330-352
    • Takemura, G.1    Fujiwara, H.2
  • 143
    • 33947285105 scopus 로고    scopus 로고
    • Docetaxel/anthracycline combinations for breast cancer treatment
    • von Minckwitz G. Docetaxel/anthracycline combinations for breast cancer treatment. Expert Opin. Pharmacother. 8 4 (2007) 485-495
    • (2007) Expert Opin. Pharmacother. , vol.8 , Issue.4 , pp. 485-495
    • von Minckwitz, G.1
  • 144
    • 33745616150 scopus 로고    scopus 로고
    • Inflammatory breast cancer: current concepts in local management
    • Bristol I.J., and Buchholz T.A. Inflammatory breast cancer: current concepts in local management. Breast Dis. 22 (2005) 75-83
    • (2005) Breast Dis. , vol.22 , pp. 75-83
    • Bristol, I.J.1    Buchholz, T.A.2
  • 145
    • 33847014237 scopus 로고    scopus 로고
    • Phase II trial of pegylated liposomal doxorubicin (Caelyx) plus Gemcitabine in chemotherapeutically pretreated patients with advanced breast cancer
    • Ulrich-Pur H., Kornek G.V., Haider K., Kwasny W., Payrits T., Dworan N., Vormittag L., Depisch D., Lang F., and Scheithauer W. Phase II trial of pegylated liposomal doxorubicin (Caelyx) plus Gemcitabine in chemotherapeutically pretreated patients with advanced breast cancer. Acta Oncol. 46 2 (2007) 208-213
    • (2007) Acta Oncol. , vol.46 , Issue.2 , pp. 208-213
    • Ulrich-Pur, H.1    Kornek, G.V.2    Haider, K.3    Kwasny, W.4    Payrits, T.5    Dworan, N.6    Vormittag, L.7    Depisch, D.8    Lang, F.9    Scheithauer, W.10
  • 148
    • 34249826079 scopus 로고    scopus 로고
    • A multicentre phase II study of carboplatin plus pegylated liposomal doxorubicin as first-line chemotherapy for patients with advanced or recurrent endometrial carcinoma: the END-1 study of the MITO (Multicentre Italian Trials in Ovarian Cancer and Gynecologic Malignancies) group
    • Pignata S., Scambia G., Pisano C., Breda E., Di Maio M., Greggi S., Ferrandina G., Lorusso D., Zagonel V., Febbraro A., Riva N., De R.V., Gallo C., and Perrone F. A multicentre phase II study of carboplatin plus pegylated liposomal doxorubicin as first-line chemotherapy for patients with advanced or recurrent endometrial carcinoma: the END-1 study of the MITO (Multicentre Italian Trials in Ovarian Cancer and Gynecologic Malignancies) group. Br. J. Cancer 96 (2007) 1639-1643
    • (2007) Br. J. Cancer , vol.96 , pp. 1639-1643
    • Pignata, S.1    Scambia, G.2    Pisano, C.3    Breda, E.4    Di Maio, M.5    Greggi, S.6    Ferrandina, G.7    Lorusso, D.8    Zagonel, V.9    Febbraro, A.10    Riva, N.11    De, R.V.12    Gallo, C.13    Perrone, F.14
  • 149
    • 0036159646 scopus 로고    scopus 로고
    • A phase II study of etoposide, doxorubicin, and carboplatin in the treatment of advanced gastric cancer
    • Wang X., Pang L., and Feng J. A phase II study of etoposide, doxorubicin, and carboplatin in the treatment of advanced gastric cancer. Am. J. Clin. Oncol. 25 1 (2002) 71-75
    • (2002) Am. J. Clin. Oncol. , vol.25 , Issue.1 , pp. 71-75
    • Wang, X.1    Pang, L.2    Feng, J.3
  • 152
    • 33845873349 scopus 로고    scopus 로고
    • AIDS-related non-Hodgkin's lymphoma in the first decade of highly active antiretroviral therapy
    • Palmieri C., Treibel T., Large O., and Bower M. AIDS-related non-Hodgkin's lymphoma in the first decade of highly active antiretroviral therapy. QJM 99 12 (2006) 811-826
    • (2006) QJM , vol.99 , Issue.12 , pp. 811-826
    • Palmieri, C.1    Treibel, T.2    Large, O.3    Bower, M.4
  • 153
    • 9444229109 scopus 로고    scopus 로고
    • Consolidation radiation after complete remission in Hodgkin's disease following six cycles of doxorubicin, bleomycin, vinblastine, and dacarbazine chemotherapy: is there a need?
    • Laskar S., Gupta T., Vimal S., Muckaden M.A., Saikia T.K., Pai S.K., Naresh K.N., and Dinshaw K.A. Consolidation radiation after complete remission in Hodgkin's disease following six cycles of doxorubicin, bleomycin, vinblastine, and dacarbazine chemotherapy: is there a need?. J. Clin. Oncol. 22 1 (2004) 62-68
    • (2004) J. Clin. Oncol. , vol.22 , Issue.1 , pp. 62-68
    • Laskar, S.1    Gupta, T.2    Vimal, S.3    Muckaden, M.A.4    Saikia, T.K.5    Pai, S.K.6    Naresh, K.N.7    Dinshaw, K.A.8
  • 155
    • 0345707586 scopus 로고    scopus 로고
    • Pattern of disease recurrence and prognostic factors in patients with osteosarcoma treated with contemporary chemotherapy
    • Hawkins D.S., and Arndt C.A. Pattern of disease recurrence and prognostic factors in patients with osteosarcoma treated with contemporary chemotherapy. Cancer 98 11 (2003) 2447-2456
    • (2003) Cancer , vol.98 , Issue.11 , pp. 2447-2456
    • Hawkins, D.S.1    Arndt, C.A.2
  • 157
    • 0031058252 scopus 로고    scopus 로고
    • Chemotherapeutic induction of long-term remission in metastatic medulloblastoma
    • Leo E., Schlegel P.G., and Lindemann A. Chemotherapeutic induction of long-term remission in metastatic medulloblastoma. J. Neurooncol. 32 2 (1997) 149-154
    • (1997) J. Neurooncol. , vol.32 , Issue.2 , pp. 149-154
    • Leo, E.1    Schlegel, P.G.2    Lindemann, A.3
  • 158
    • 0032997108 scopus 로고    scopus 로고
    • Doxorubicin-induced cell death in highly invasive human gliomas
    • Stan A.C., Casares S., Radu D., Walter G.F., and Brumeanu T.D. Doxorubicin-induced cell death in highly invasive human gliomas. Anticancer Res. 19 2A (1999) 941-950
    • (1999) Anticancer Res. , vol.19 , Issue.2 A , pp. 941-950
    • Stan, A.C.1    Casares, S.2    Radu, D.3    Walter, G.F.4    Brumeanu, T.D.5
  • 159
    • 0344118130 scopus 로고    scopus 로고
    • BR96-DOX immunoconjugate targeting of chemotherapy in brain tumor models
    • Muldoon L.L., and Neuwelt E.A. BR96-DOX immunoconjugate targeting of chemotherapy in brain tumor models. J. Neurooncol. 65 1 (2003) 49-62
    • (2003) J. Neurooncol. , vol.65 , Issue.1 , pp. 49-62
    • Muldoon, L.L.1    Neuwelt, E.A.2
  • 160
    • 34248577328 scopus 로고    scopus 로고
    • Monoclonal antibody 2C5-modified doxorubicin-loaded liposomes with significantly enhanced therapeutic activity against intracranial human brain U-87 MG tumor xenografts in nude mice
    • Gupta B., and Torchilin V.P. Monoclonal antibody 2C5-modified doxorubicin-loaded liposomes with significantly enhanced therapeutic activity against intracranial human brain U-87 MG tumor xenografts in nude mice. Cancer Immunol. Immunother. 56 8 (2007) 1215-1223
    • (2007) Cancer Immunol. Immunother. , vol.56 , Issue.8 , pp. 1215-1223
    • Gupta, B.1    Torchilin, V.P.2
  • 161
    • 0022474105 scopus 로고
    • Studies on the in vivo disposition of adriamycin in human tumours which exhibit different responses to the drug
    • Cummings J., and McArdle C.S. Studies on the in vivo disposition of adriamycin in human tumours which exhibit different responses to the drug. Br. J. Cancer 53 6 (1986) 835-838
    • (1986) Br. J. Cancer , vol.53 , Issue.6 , pp. 835-838
    • Cummings, J.1    McArdle, C.S.2
  • 162
  • 164
    • 0001891219 scopus 로고
    • Physics of acoustic cavitation in liquids
    • Mason W.P. (Ed), Academic Press, New York
    • Flynn H.G. Physics of acoustic cavitation in liquids. In: Mason W.P. (Ed). Physical Acoustics, Principles and Methods (1964), Academic Press, New York
    • (1964) Physical Acoustics, Principles and Methods
    • Flynn, H.G.1
  • 166
    • 0035003478 scopus 로고    scopus 로고
    • Biological effects of ultrasound: development of safety guidelines. Part II: general review
    • Nyborg W.L. Biological effects of ultrasound: development of safety guidelines. Part II: general review. Ultrasound Med. Biol. 27 3 (2001) 301-333
    • (2001) Ultrasound Med. Biol. , vol.27 , Issue.3 , pp. 301-333
    • Nyborg, W.L.1
  • 167
    • 0001706586 scopus 로고
    • Theory of rectified diffusion of mass into gas bubbles
    • Hsieh D.Y., and Plesset M.S. Theory of rectified diffusion of mass into gas bubbles. J. Acoust. Soc. Am. 33 (1961) 206-211
    • (1961) J. Acoust. Soc. Am. , vol.33 , pp. 206-211
    • Hsieh, D.Y.1    Plesset, M.S.2
  • 168
    • 85012738841 scopus 로고
    • Acoustic streaming
    • Mason W.P. (Ed), Academic Press, New York
    • Nyborg W.L. Acoustic streaming. In: Mason W.P. (Ed). Physical Acoustics (1965), Academic Press, New York
    • (1965) Physical Acoustics
    • Nyborg, W.L.1
  • 169
    • 0023392781 scopus 로고
    • A review of the ultrasonic bioeffects of microsonation, gas-body activation, and related cavitation-like phenomena
    • Miller D.L. A review of the ultrasonic bioeffects of microsonation, gas-body activation, and related cavitation-like phenomena. Ultrasound Med. Biol. 13 8 (1987) 443-470
    • (1987) Ultrasound Med. Biol. , vol.13 , Issue.8 , pp. 443-470
    • Miller, D.L.1
  • 170
    • 10344259085 scopus 로고    scopus 로고
    • The cerebral vasculature as a therapeutic target for neurological disorders and the role of shear stress in vascular homeostatis and pathophysiology
    • Krizanac-Bengez L., Mayberg M.R., and Janigro D. The cerebral vasculature as a therapeutic target for neurological disorders and the role of shear stress in vascular homeostatis and pathophysiology. Neurol. Res. 26 8 (2004) 846-853
    • (2004) Neurol. Res. , vol.26 , Issue.8 , pp. 846-853
    • Krizanac-Bengez, L.1    Mayberg, M.R.2    Janigro, D.3
  • 172
    • 33751101567 scopus 로고    scopus 로고
    • Twenty odd years of stretch-sensitive channels
    • Hamill O.P. Twenty odd years of stretch-sensitive channels. Pflugers Arch. 453 3 (2006) 333-351
    • (2006) Pflugers Arch. , vol.453 , Issue.3 , pp. 333-351
    • Hamill, O.P.1
  • 173
    • 0024987708 scopus 로고
    • Temporally-specific modification of myelinated axon excitability in vitro following a single ultrasound pulse
    • Mihran R.T., Barnes F.S., and Wachtel H. Temporally-specific modification of myelinated axon excitability in vitro following a single ultrasound pulse. Ultrasound Med. Biol. 16 3 (1990) 297-309
    • (1990) Ultrasound Med. Biol. , vol.16 , Issue.3 , pp. 297-309
    • Mihran, R.T.1    Barnes, F.S.2    Wachtel, H.3
  • 174
    • 0025672718 scopus 로고
    • Transient modification of nerve excitability in vitro by single ultrasound pulses
    • Mihran R.T., Barnes F.S., and Wachtel H. Transient modification of nerve excitability in vitro by single ultrasound pulses. Biomed. Sci. Instrum. 26 (1990) 235-246
    • (1990) Biomed. Sci. Instrum. , vol.26 , pp. 235-246
    • Mihran, R.T.1    Barnes, F.S.2    Wachtel, H.3
  • 175
    • 0019974522 scopus 로고
    • Acoustic cavitation: a possible consequence of biomedical uses of ultrasound
    • Apfel R.E. Acoustic cavitation: a possible consequence of biomedical uses of ultrasound. Br. J. Cancer Suppl. 45 5 (1982) 140-146
    • (1982) Br. J. Cancer Suppl. , vol.45 , Issue.5 , pp. 140-146
    • Apfel, R.E.1
  • 176
    • 0020331048 scopus 로고
    • Generation of transient cavities in liquids by microsecond pulses of ultrasound
    • Flynn H.G. Generation of transient cavities in liquids by microsecond pulses of ultrasound. J. Acoust. Soc. Am. 72 (1982) 1926-1932
    • (1982) J. Acoust. Soc. Am. , vol.72 , pp. 1926-1932
    • Flynn, H.G.1
  • 177
    • 1842455119 scopus 로고    scopus 로고
    • The role of cavitation microjets in the therapeutic applications of ultrasound
    • Brujan E.A. The role of cavitation microjets in the therapeutic applications of ultrasound. Ultrasound Med. Biol. 30 3 (2004) 381-387
    • (2004) Ultrasound Med. Biol. , vol.30 , Issue.3 , pp. 381-387
    • Brujan, E.A.1
  • 178
    • 33746460753 scopus 로고    scopus 로고
    • Jets from collapsing bubbles
    • Katz J.I. Jets from collapsing bubbles. Proc. R. Soc. London, Ser. A. 455 (1999) 323-328
    • (1999) Proc. R. Soc. London, Ser. A. , vol.455 , pp. 323-328
    • Katz, J.I.1
  • 179
    • 0026661474 scopus 로고
    • Free radical formation induced by ultrasound and its biological implications
    • Riesz P., and Kondo T. Free radical formation induced by ultrasound and its biological implications. Free Radical Biol. Med. 13 3 (1992) 247-270
    • (1992) Free Radical Biol. Med. , vol.13 , Issue.3 , pp. 247-270
    • Riesz, P.1    Kondo, T.2
  • 180
    • 0021070062 scopus 로고
    • Evidence for free radical production by ultrasonic cavitation in biological media
    • Edmonds P.D., and Sancier K.M. Evidence for free radical production by ultrasonic cavitation in biological media. Ultrasound Med. Biol. 9 6 (1983) 635-639
    • (1983) Ultrasound Med. Biol. , vol.9 , Issue.6 , pp. 635-639
    • Edmonds, P.D.1    Sancier, K.M.2
  • 181
    • 0027712097 scopus 로고
    • Free radical formation induced by ultrasound and its effects on strand breaks in DNA of cultured FM3A cells
    • Kondo T., Kodaira T., and Kano E. Free radical formation induced by ultrasound and its effects on strand breaks in DNA of cultured FM3A cells. Free Radical Res. Commun. 19 Suppl. 1 (1993) S193-S200
    • (1993) Free Radical Res. Commun. , vol.19 , Issue.SUPPL. 1
    • Kondo, T.1    Kodaira, T.2    Kano, E.3
  • 182
  • 183
    • 0030442881 scopus 로고    scopus 로고
    • A review of in vitro bioeffects of inertial ultrasonic cavitation from a mechanistic perspective
    • Miller M.W., Miller D.L., and Brayman A.A. A review of in vitro bioeffects of inertial ultrasonic cavitation from a mechanistic perspective. Ultrasound Med. Biol. 22 9 (1996) 1131-1154
    • (1996) Ultrasound Med. Biol. , vol.22 , Issue.9 , pp. 1131-1154
    • Miller, M.W.1    Miller, D.L.2    Brayman, A.A.3
  • 184
    • 0029103388 scopus 로고
    • Ultrasound contrast agents nucleate inertial cavitation in vitro
    • Miller D.L., and Thomas R.M. Ultrasound contrast agents nucleate inertial cavitation in vitro. Ultrasound Med. Biol. 21 8 (1995) 1059-1065
    • (1995) Ultrasound Med. Biol. , vol.21 , Issue.8 , pp. 1059-1065
    • Miller, D.L.1    Thomas, R.M.2
  • 185
    • 8844228263 scopus 로고    scopus 로고
    • Micromanipulation of endothelial cells: ultrasound-microbubble-cell interaction
    • van Wamel A., Bouakaz A., Versluis M., and de Jong N. Micromanipulation of endothelial cells: ultrasound-microbubble-cell interaction. Ultrasound Med. Biol. 30 9 (2004) 1255-1258
    • (2004) Ultrasound Med. Biol. , vol.30 , Issue.9 , pp. 1255-1258
    • van Wamel, A.1    Bouakaz, A.2    Versluis, M.3    de Jong, N.4
  • 186
    • 0015022804 scopus 로고    scopus 로고
    • Acoustic detection of single cavitation events in a focused field in water at 1 MHz
    • Coakley W.T. Acoustic detection of single cavitation events in a focused field in water at 1 MHz. J. Acoust. Soc. Am. 49 (2006) 792
    • (2006) J. Acoust. Soc. Am. , vol.49 , pp. 792
    • Coakley, W.T.1
  • 187
    • 45949127155 scopus 로고
    • Acoustic cavitation
    • Neppiras E.A. Acoustic cavitation. Phys. Rep. 61 (1980) 160
    • (1980) Phys. Rep. , vol.61 , pp. 160
    • Neppiras, E.A.1
  • 188
    • 0003121707 scopus 로고
    • Effects of ultrasound on solid mammalian tissues and tumors in vivo
    • Repacholi M.H., Grandolfo M., and Rindi A. (Eds), Plunum Publishing Corporation, New York
    • Lele P.P. Effects of ultrasound on solid mammalian tissues and tumors in vivo. In: Repacholi M.H., Grandolfo M., and Rindi A. (Eds). Ultrasound: Medical Applications, Biological Effects and Hazard Potential (1987), Plunum Publishing Corporation, New York 275-306
    • (1987) Ultrasound: Medical Applications, Biological Effects and Hazard Potential , pp. 275-306
    • Lele, P.P.1
  • 189
    • 0035060321 scopus 로고    scopus 로고
    • Dynamics of bubble oscillation in constrained media and mechanisms of vessel rupture in SWL
    • Zhong P., Zhou Y., and Zhu S. Dynamics of bubble oscillation in constrained media and mechanisms of vessel rupture in SWL. Ultrasound Med. Biol. 27 1 (2001) 119-134
    • (2001) Ultrasound Med. Biol. , vol.27 , Issue.1 , pp. 119-134
    • Zhong, P.1    Zhou, Y.2    Zhu, S.3
  • 190
    • 2942654748 scopus 로고    scopus 로고
    • Forced linear oscillations of microbubbles in blood capillaries
    • Sassaroli E., and Hynynen K. Forced linear oscillations of microbubbles in blood capillaries. J. Acoust. Soc. Am. 115 (2004) 3235-3243
    • (2004) J. Acoust. Soc. Am. , vol.115 , pp. 3235-3243
    • Sassaroli, E.1    Hynynen, K.2
  • 191
    • 27644469133 scopus 로고    scopus 로고
    • Resonance frequency of microbubbles in small blood vessels: a numerical study
    • Sassaroli E., and Hynynen K. Resonance frequency of microbubbles in small blood vessels: a numerical study. Phys. Med. Biol. 50 22 (2005) 5293-5305
    • (2005) Phys. Med. Biol. , vol.50 , Issue.22 , pp. 5293-5305
    • Sassaroli, E.1    Hynynen, K.2
  • 193
  • 194
    • 33749605662 scopus 로고    scopus 로고
    • Acoustic response of compliable microvessels containing ultrasound contrast agents
    • Qin S., and Ferrara K.W. Acoustic response of compliable microvessels containing ultrasound contrast agents. Phys. Med. Biol. 27 (2006) 5063-5088
    • (2006) Phys. Med. Biol. , vol.27 , pp. 5063-5088
    • Qin, S.1    Ferrara, K.W.2
  • 195
    • 34548854775 scopus 로고    scopus 로고
    • Cavitation thresholds of microbubbles in gel tunnels by focused ultrasound
    • Sassaroli E., and Hynynen K. Cavitation thresholds of microbubbles in gel tunnels by focused ultrasound. Ultrasound Med. Biol. 33 10 (2007) 1651-1660
    • (2007) Ultrasound Med. Biol. , vol.33 , Issue.10 , pp. 1651-1660
    • Sassaroli, E.1    Hynynen, K.2
  • 196
    • 0037196258 scopus 로고    scopus 로고
    • A new method for the investigation of capillary structure
    • Tata D.A., and Anderson B.J. A new method for the investigation of capillary structure. J. Neurosci. Methods 113 2 (2002) 199-206
    • (2002) J. Neurosci. Methods , vol.113 , Issue.2 , pp. 199-206
    • Tata, D.A.1    Anderson, B.J.2
  • 197
    • 0033496026 scopus 로고    scopus 로고
    • Dynamic in vivo measurement of erythrocyte velocity and flow in capillaries and of microvessel diameter in the rat brain by confocal laser microscopy
    • Seylaz J., Charbonne R., Nanri K., Von Euw D., Borredon J., Kacem K., Meric P., and Pinard E. Dynamic in vivo measurement of erythrocyte velocity and flow in capillaries and of microvessel diameter in the rat brain by confocal laser microscopy. J. Cereb. Blood Flow Metab. 19 8 (1999) 863-870
    • (1999) J. Cereb. Blood Flow Metab. , vol.19 , Issue.8 , pp. 863-870
    • Seylaz, J.1    Charbonne, R.2    Nanri, K.3    Von Euw, D.4    Borredon, J.5    Kacem, K.6    Meric, P.7    Pinard, E.8
  • 198
    • 13144304679 scopus 로고
    • The one-dimensional bubble: an unusual oscillator, with applications to human bioeffects of underwater sound
    • Leighton T.G., White P.R., and Marsden M.A. The one-dimensional bubble: an unusual oscillator, with applications to human bioeffects of underwater sound. Eur. J. Phys. 16 (1995) 275-281
    • (1995) Eur. J. Phys. , vol.16 , pp. 275-281
    • Leighton, T.G.1    White, P.R.2    Marsden, M.A.3
  • 199
    • 0041048620 scopus 로고
    • Applications of one-dimensional bubbles to lithotripsy, and to diver response to low frequency sound
    • Leighton T.G., White P.R., and Marsden M.A. Applications of one-dimensional bubbles to lithotripsy, and to diver response to low frequency sound. Acta Acoust. 3 (1995) 517-529
    • (1995) Acta Acoust. , vol.3 , pp. 517-529
    • Leighton, T.G.1    White, P.R.2    Marsden, M.A.3
  • 200
    • 4143081639 scopus 로고    scopus 로고
    • Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles
    • Sheikov N., McDannold N., Vykhodtseva N., Jolesz F., and Hynynen K. Cellular mechanisms of the blood-brain barrier opening induced by ultrasound in presence of microbubbles. Ultrasound Med. Biol. 30 7 (2004) 979-989
    • (2004) Ultrasound Med. Biol. , vol.30 , Issue.7 , pp. 979-989
    • Sheikov, N.1    McDannold, N.2    Vykhodtseva, N.3    Jolesz, F.4    Hynynen, K.5
  • 201
    • 33748325638 scopus 로고    scopus 로고
    • Brain arterioles show more active vesicular transport of blood-borne tracer molecules than capillaries and venules after focused ultrasound-evoked opening of the blood-brain barrier
    • Sheikov N., McDannold N., Jolesz F., Zhang Y.Z., Tam K., and Hynynen K. Brain arterioles show more active vesicular transport of blood-borne tracer molecules than capillaries and venules after focused ultrasound-evoked opening of the blood-brain barrier. Ultrasound Med. Biol. 32 9 (2006) 1399-1409
    • (2006) Ultrasound Med. Biol. , vol.32 , Issue.9 , pp. 1399-1409
    • Sheikov, N.1    McDannold, N.2    Jolesz, F.3    Zhang, Y.Z.4    Tam, K.5    Hynynen, K.6
  • 202
    • 45949097554 scopus 로고    scopus 로고
    • N. Sheikov, N. McDannold, S. Sharma, K. Hynynen, Effect of focused ultrasound applied with an ultrasound contrast agent on the tight junctional integrity of the brain microvascular endothelium, Ultrasound Med. Biol. (2008), in press.
    • N. Sheikov, N. McDannold, S. Sharma, K. Hynynen, Effect of focused ultrasound applied with an ultrasound contrast agent on the tight junctional integrity of the brain microvascular endothelium, Ultrasound Med. Biol. (2008), in press.
  • 204
    • 33846438234 scopus 로고    scopus 로고
    • Multiphoton imaging of ultrasound/Optison mediated cerebrovascular effects in vivo
    • Raymond S.B., Skoch J., Hynynen K., and Bacskai B.J. Multiphoton imaging of ultrasound/Optison mediated cerebrovascular effects in vivo. J. Cereb. Blood Flow Metab. 27 2 (2007) 393-403
    • (2007) J. Cereb. Blood Flow Metab. , vol.27 , Issue.2 , pp. 393-403
    • Raymond, S.B.1    Skoch, J.2    Hynynen, K.3    Bacskai, B.J.4
  • 205
    • 0034953204 scopus 로고    scopus 로고
    • Mechanisms of spreading depression and hypoxic spreading depression-like depolarization
    • Somjen G.G. Mechanisms of spreading depression and hypoxic spreading depression-like depolarization. Physiol. Rev. 81 3 (2001) 1065-1096
    • (2001) Physiol. Rev. , vol.81 , Issue.3 , pp. 1065-1096
    • Somjen, G.G.1
  • 206
    • 0001152951 scopus 로고
    • Pial circulation and spreading depression activity in cerebral cortex
    • Leao A.A.P. Pial circulation and spreading depression activity in cerebral cortex. J. Neurophysiol. 7 (1944) 391-396
    • (1944) J. Neurophysiol. , vol.7 , pp. 391-396
    • Leao, A.A.P.1
  • 207
    • 4143147483 scopus 로고    scopus 로고
    • Spreading depression induces long-lasting brain protection against infarcted lesion development via BDNF gene-dependent mechanism
    • Yanamoto H., Xue J.H., Miyamoto S., Nagata I., Nakano Y., Murao K., and Kikuchi H. Spreading depression induces long-lasting brain protection against infarcted lesion development via BDNF gene-dependent mechanism. Brain Res. 1019 1-2 (2004) 178-188
    • (2004) Brain Res. , vol.1019 , Issue.1-2 , pp. 178-188
    • Yanamoto, H.1    Xue, J.H.2    Miyamoto, S.3    Nagata, I.4    Nakano, Y.5    Murao, K.6    Kikuchi, H.7
  • 208
    • 22044458290 scopus 로고    scopus 로고
    • Induced spreading depression activates persistent neurogenesis in the subventricular zone, generating cells with markers for divided and early committed neurons in the caudate putamen and cortex
    • Yanamoto H., Miyamoto S., Tohnai N., Nagata I., Xue J.H., Nakano Y., Nakajo Y., and Kikuchi H. Induced spreading depression activates persistent neurogenesis in the subventricular zone, generating cells with markers for divided and early committed neurons in the caudate putamen and cortex. Stroke 36 7 (2005) 1544-1550
    • (2005) Stroke , vol.36 , Issue.7 , pp. 1544-1550
    • Yanamoto, H.1    Miyamoto, S.2    Tohnai, N.3    Nagata, I.4    Xue, J.H.5    Nakano, Y.6    Nakajo, Y.7    Kikuchi, H.8
  • 210
    • 48149098139 scopus 로고    scopus 로고
    • N. Vykhodtseva, V.I. Koroleva, Steady potential changes and spreading depression in rat brains produced by focused ultrasound, in: G. Clement et al. (Ed.), Therapeutic Ultrasound, AIP Conference Proceedings ISTU2005, Boston, MA, 2006, pp. 313-317.
    • N. Vykhodtseva, V.I. Koroleva, Steady potential changes and spreading depression in rat brains produced by focused ultrasound, in: G. Clement et al. (Ed.), Therapeutic Ultrasound, AIP Conference Proceedings ISTU2005, Boston, MA, 2006, pp. 313-317.
  • 211
    • 48149099400 scopus 로고    scopus 로고
    • N. Vykhodtseva, I.I. Konopatskaya, V.I. Koroleva, Focused ultrasound potential to initiate spreading depression for disruption of blood-brain barrier, in: 2007 IEEE Ultrasonics Symposium New York City, NY, 28-31 October 2007, pp. 428-431.
    • N. Vykhodtseva, I.I. Konopatskaya, V.I. Koroleva, Focused ultrasound potential to initiate spreading depression for disruption of blood-brain barrier, in: 2007 IEEE Ultrasonics Symposium New York City, NY, 28-31 October 2007, pp. 428-431.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.