메뉴 건너뛰기




Volumn 659, Issue 1-2, 2008, Pages 109-117

Sixty years of follow-up of Hiroshima and Nagasaki survivors: Current progress in molecular epidemiology studies

Author keywords

Atomic bomb survivors; Colorectal carcinogenesis; Microsatellite instability; Oxidative stress; Radiation; Somatic mutation; Thyroid carcinogenesis

Indexed keywords

B RAF KINASE; GLYCOPHORIN A; HISTONE H2AX;

EID: 47849124251     PISSN: 13835742     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrrev.2008.02.001     Document Type: Review
Times cited : (36)

References (41)
  • 1
    • 36749050926 scopus 로고    scopus 로고
    • Long-lasting alterations of the immune system by ionizing radiation exposure: implications for disease development among atomic bomb survivors
    • Kusunoki Y., and Hayashi T. Long-lasting alterations of the immune system by ionizing radiation exposure: implications for disease development among atomic bomb survivors. Int. J. Radiat. Biol. 84 (2007) 1-14
    • (2007) Int. J. Radiat. Biol. , vol.84 , pp. 1-14
    • Kusunoki, Y.1    Hayashi, T.2
  • 2
    • 20444462766 scopus 로고    scopus 로고
    • Individual variation of somatic gene mutability in relation to cancer susceptibility: prospective study on erythrocyte glycophorin A gene mutations of atomic bomb survivors
    • Kyoizumi S., Kusunoki Y., Hayashi T., Hakoda M., Cologne J.B., and Nakachi K. Individual variation of somatic gene mutability in relation to cancer susceptibility: prospective study on erythrocyte glycophorin A gene mutations of atomic bomb survivors. Cancer Res. 65 (2005) 5462-5469
    • (2005) Cancer Res. , vol.65 , pp. 5462-5469
    • Kyoizumi, S.1    Kusunoki, Y.2    Hayashi, T.3    Hakoda, M.4    Cologne, J.B.5    Nakachi, K.6
  • 3
    • 33846913205 scopus 로고    scopus 로고
    • Short-term culture and γH2AX flow cytometry determine differences in individual radiosensitivity in human peripheral T lymphocytes
    • Hamasaki K., Imai K., Nakachi K., Takahashi N., Kodama Y., and Kusunoki Y. Short-term culture and γH2AX flow cytometry determine differences in individual radiosensitivity in human peripheral T lymphocytes. Environ. Mol. Mutagen. 48 (2007) 38-47
    • (2007) Environ. Mol. Mutagen. , vol.48 , pp. 38-47
    • Hamasaki, K.1    Imai, K.2    Nakachi, K.3    Takahashi, N.4    Kodama, Y.5    Kusunoki, Y.6
  • 4
    • 35549010540 scopus 로고    scopus 로고
    • Radiation sensitivity and genomic instability in the hematopoietic system: frequencies of micronucleated reticulocytes in whole-body X-irradiated BALB/c and C57BL/6 mice
    • Hamasaki K., Imai K., Hayashi T., Nakachi K., and Kusunoki Y. Radiation sensitivity and genomic instability in the hematopoietic system: frequencies of micronucleated reticulocytes in whole-body X-irradiated BALB/c and C57BL/6 mice. Cancer Sci. 98 (2007) 1840-1844
    • (2007) Cancer Sci. , vol.98 , pp. 1840-1844
    • Hamasaki, K.1    Imai, K.2    Hayashi, T.3    Nakachi, K.4    Kusunoki, Y.5
  • 7
    • 0029957134 scopus 로고    scopus 로고
    • Somatic cell mutations at the glycophorin A locus in erythrocytes of atomic-bomb survivors: implications for radiation carcinogenesis
    • Kyoizumi S., Akiyama M., Cologne J.B., Tanabe K., Nakamura N., Awa A.A., Hirai Y., Kusunoki Y., and Umeki S. Somatic cell mutations at the glycophorin A locus in erythrocytes of atomic-bomb survivors: implications for radiation carcinogenesis. Radiat. Res. 146 (1996) 43-52
    • (1996) Radiat. Res. , vol.146 , pp. 43-52
    • Kyoizumi, S.1    Akiyama, M.2    Cologne, J.B.3    Tanabe, K.4    Nakamura, N.5    Awa, A.A.6    Hirai, Y.7    Kusunoki, Y.8    Umeki, S.9
  • 8
    • 0024529511 scopus 로고
    • Detection of somatic mutations at the glycophorin A locus in erythrocytes of atomic bomb survivors using a single beam flow sorter
    • Kyoizumi S., Nakamura N., Hakoda M., Awa A.A., Bean M.A., Jensen R.H., and Akiyama M. Detection of somatic mutations at the glycophorin A locus in erythrocytes of atomic bomb survivors using a single beam flow sorter. Cancer Res. 49 (1989) 581-588
    • (1989) Cancer Res. , vol.49 , pp. 581-588
    • Kyoizumi, S.1    Nakamura, N.2    Hakoda, M.3    Awa, A.A.4    Bean, M.A.5    Jensen, R.H.6    Akiyama, M.7
  • 9
    • 0032489520 scopus 로고    scopus 로고
    • DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
    • Rogakou E.P., Pilch D.R., Orr A.H., Ivanova V.S., and Bonner W.M. DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J. Biol. Chem. 273 (1998) 5858-5868
    • (1998) J. Biol. Chem. , vol.273 , pp. 5858-5868
    • Rogakou, E.P.1    Pilch, D.R.2    Orr, A.H.3    Ivanova, V.S.4    Bonner, W.M.5
  • 10
    • 0032861343 scopus 로고    scopus 로고
    • Megabase chromatin domains involved in DNA double-strand breaks in vivo
    • Rogakou E.P., Boon C., Redon C., and Bonner W.M. Megabase chromatin domains involved in DNA double-strand breaks in vivo. J. Cell Biol. 146 (1999) 905-916
    • (1999) J. Cell Biol. , vol.146 , pp. 905-916
    • Rogakou, E.P.1    Boon, C.2    Redon, C.3    Bonner, W.M.4
  • 11
    • 26444553297 scopus 로고    scopus 로고
    • Does γH2AX foci formation depend on the presence of DNA double strand breaks?
    • Takahashi A., and Ohnishi T. Does γH2AX foci formation depend on the presence of DNA double strand breaks?. Cancer Lett. 229 (2005) 171-179
    • (2005) Cancer Lett. , vol.229 , pp. 171-179
    • Takahashi, A.1    Ohnishi, T.2
  • 13
    • 26244439873 scopus 로고    scopus 로고
    • ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells
    • McManus K.J., and Hendzel M.J. ATM-dependent DNA damage-independent mitotic phosphorylation of H2AX in normally growing mammalian cells. Mol. Biol. Cell 16 (2005) 5013-5025
    • (2005) Mol. Biol. Cell , vol.16 , pp. 5013-5025
    • McManus, K.J.1    Hendzel, M.J.2
  • 14
    • 0242490151 scopus 로고    scopus 로고
    • Radiation-induced genomic instability and bystander effects: inter-related nontargeted effects of exposure to ionizing radiation
    • Lorimore S.A., Coates P.J., and Wright E.G. Radiation-induced genomic instability and bystander effects: inter-related nontargeted effects of exposure to ionizing radiation. Oncogene 22 (2003) 7058-7069
    • (2003) Oncogene , vol.22 , pp. 7058-7069
    • Lorimore, S.A.1    Coates, P.J.2    Wright, E.G.3
  • 15
    • 0026699766 scopus 로고
    • Flow-cytometric enumeration of micronucleated polychromatic erythrocytes in mouse peripheral blood
    • Grawe J., Zetterberg G., and Amneus H. Flow-cytometric enumeration of micronucleated polychromatic erythrocytes in mouse peripheral blood. Cytometry 13 (1992) 750-758
    • (1992) Cytometry , vol.13 , pp. 750-758
    • Grawe, J.1    Zetterberg, G.2    Amneus, H.3
  • 16
    • 0030595997 scopus 로고    scopus 로고
    • Simple and reliable enumeration of micronucleated reticulocytes with a single-laser flow cytometer
    • Dertinger S.D., Torous D.K., and Tometsko K.R. Simple and reliable enumeration of micronucleated reticulocytes with a single-laser flow cytometer. Mutat. Res. 371 (1996) 283-292
    • (1996) Mutat. Res. , vol.371 , pp. 283-292
    • Dertinger, S.D.1    Torous, D.K.2    Tometsko, K.R.3
  • 17
    • 0032480034 scopus 로고    scopus 로고
    • An automated new technique for scoring the rodent micronucleus assay: computerized image analysis of acridine orange supravitally stained peripheral blood cells
    • Asano N., Katsuma Y., Tamura H., Higashikuni N., and Hayashi M. An automated new technique for scoring the rodent micronucleus assay: computerized image analysis of acridine orange supravitally stained peripheral blood cells. Mutat. Res. 404 (1998) 149-154
    • (1998) Mutat. Res. , vol.404 , pp. 149-154
    • Asano, N.1    Katsuma, Y.2    Tamura, H.3    Higashikuni, N.4    Hayashi, M.5
  • 18
    • 33947188218 scopus 로고    scopus 로고
    • An assessment of recombinant human erythropoietin effect on reticulocyte production rate and lifespan distribution in healthy subjects
    • Krzyzanski W., and Perez-Ruixo J.J. An assessment of recombinant human erythropoietin effect on reticulocyte production rate and lifespan distribution in healthy subjects. Pharm. Res. 24 (2007) 758-772
    • (2007) Pharm. Res. , vol.24 , pp. 758-772
    • Krzyzanski, W.1    Perez-Ruixo, J.J.2
  • 19
    • 18144389039 scopus 로고    scopus 로고
    • Evaluation of the reticulocyte micronucleus assay in patients treated with radioiodine for thyroid cancer
    • Grawe J., Biko J., Lorenz R., Reiners C., Stopper H., Vershenya S., Vukicevic V., and Hempel K. Evaluation of the reticulocyte micronucleus assay in patients treated with radioiodine for thyroid cancer. Mutat. Res. 583 (2005) 12-25
    • (2005) Mutat. Res. , vol.583 , pp. 12-25
    • Grawe, J.1    Biko, J.2    Lorenz, R.3    Reiners, C.4    Stopper, H.5    Vershenya, S.6    Vukicevic, V.7    Hempel, K.8
  • 21
  • 23
    • 0037379904 scopus 로고    scopus 로고
    • High prevalence of BRAF mutations in thyroid cancer: genetic evidence of constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma
    • Kimura E.T., Nikiforova M.N., Zhu Z., Knauf J.A., Nikiforov Y.E., and Fagin J.A. High prevalence of BRAF mutations in thyroid cancer: genetic evidence of constitutive activation of the RET/PTC-RAS-BRAF signaling pathway in papillary thyroid carcinoma. Cancer Res. 63 (2003) 1454-1457
    • (2003) Cancer Res. , vol.63 , pp. 1454-1457
    • Kimura, E.T.1    Nikiforova, M.N.2    Zhu, Z.3    Knauf, J.A.4    Nikiforov, Y.E.5    Fagin, J.A.6
  • 26
    • 0030941779 scopus 로고    scopus 로고
    • Distinct pattern of ret oncogene rearrangements in morphological variants of radiation-induced and sporadic thyroid papillary carcinomas in children
    • Nikiforov Y.E., Rowland J.M., Bove K.E., Monforte-Munoz H., and Fagin J.A. Distinct pattern of ret oncogene rearrangements in morphological variants of radiation-induced and sporadic thyroid papillary carcinomas in children. Cancer Res. 57 (1997) 1690-1694
    • (1997) Cancer Res. , vol.57 , pp. 1690-1694
    • Nikiforov, Y.E.1    Rowland, J.M.2    Bove, K.E.3    Monforte-Munoz, H.4    Fagin, J.A.5
  • 27
    • 0034016275 scopus 로고    scopus 로고
    • Pattern of radiation-induced RET and NTRK1 rearrangements in 191 post-Chernobyl papillary thyroid carcinomas: biological, phenotypic, and clinical implications
    • Rabes H.M., Demidchik E.P., Sidorow J.D., Lengfelder E., Beimfohr C., Hoelzel D., and Klugbauer S. Pattern of radiation-induced RET and NTRK1 rearrangements in 191 post-Chernobyl papillary thyroid carcinomas: biological, phenotypic, and clinical implications. Clin. Cancer Res. 6 (2000) 1093-1103
    • (2000) Clin. Cancer Res. , vol.6 , pp. 1093-1103
    • Rabes, H.M.1    Demidchik, E.P.2    Sidorow, J.D.3    Lengfelder, E.4    Beimfohr, C.5    Hoelzel, D.6    Klugbauer, S.7
  • 28
    • 21244457181 scopus 로고    scopus 로고
    • BRAF mutation in thyroid cancer
    • Xing M. BRAF mutation in thyroid cancer. Endocr. Related Cancer 12 (2005) 245-262
    • (2005) Endocr. Related Cancer , vol.12 , pp. 245-262
    • Xing, M.1
  • 29
    • 0030929178 scopus 로고    scopus 로고
    • High prevalence of activating ret proto-oncogene rearrangements, in thyroid tumors from patients who had received external radiation
    • Bounacer A., Wicker R., Caillou B., Cailleux A.F., Sarasin A., Schlumberger M., and Suarez H.G. High prevalence of activating ret proto-oncogene rearrangements, in thyroid tumors from patients who had received external radiation. Oncogene 15 (1997) 1263-1273
    • (1997) Oncogene , vol.15 , pp. 1263-1273
    • Bounacer, A.1    Wicker, R.2    Caillou, B.3    Cailleux, A.F.4    Sarasin, A.5    Schlumberger, M.6    Suarez, H.G.7
  • 33
    • 0033847512 scopus 로고    scopus 로고
    • Genetic and epigenetic modification of MLH1 accounts for a major share of microsatellite-unstable colorectal cancers
    • Kuismanen S.A., Holmberg M.T., Salovaara R., de la Chapelle A., and Peltomaki P. Genetic and epigenetic modification of MLH1 accounts for a major share of microsatellite-unstable colorectal cancers. Am. J. Pathol. 156 (2000) 1773-1779
    • (2000) Am. J. Pathol. , vol.156 , pp. 1773-1779
    • Kuismanen, S.A.1    Holmberg, M.T.2    Salovaara, R.3    de la Chapelle, A.4    Peltomaki, P.5
  • 34
    • 0033135049 scopus 로고    scopus 로고
    • Methylation of CpG in a small region of the hMLH1 promoter invariably correlates with the absence of gene expression
    • Deng G., Chen A., Hong J., Chae H.S., and Kim Y.S. Methylation of CpG in a small region of the hMLH1 promoter invariably correlates with the absence of gene expression. Cancer Res. 59 (1999) 2029-2033
    • (1999) Cancer Res. , vol.59 , pp. 2029-2033
    • Deng, G.1    Chen, A.2    Hong, J.3    Chae, H.S.4    Kim, Y.S.5
  • 36
    • 0036022107 scopus 로고    scopus 로고
    • Densely methylated MLH1 promoter correlates with decreased mRNA expression in sporadic colorectal cancers
    • Furukawa T., Konishi F., Masubuchi S., Shitoh K., Nagai H., and Tsukamoto T. Densely methylated MLH1 promoter correlates with decreased mRNA expression in sporadic colorectal cancers. Genes Chromosomes Cancer 35 (2002) 1-10
    • (2002) Genes Chromosomes Cancer , vol.35 , pp. 1-10
    • Furukawa, T.1    Konishi, F.2    Masubuchi, S.3    Shitoh, K.4    Nagai, H.5    Tsukamoto, T.6
  • 37
    • 0030825309 scopus 로고    scopus 로고
    • COBRA: a sensitive and quantitative DNA methylation assay
    • Xiong Z., and Laird P.W. COBRA: a sensitive and quantitative DNA methylation assay. Nucleic Acids Res. 25 (1997) 2532-2534
    • (1997) Nucleic Acids Res. , vol.25 , pp. 2532-2534
    • Xiong, Z.1    Laird, P.W.2
  • 38
    • 0035812238 scopus 로고    scopus 로고
    • Sporadic colorectal cancers with microsatellite instability and their possible origin in hyperplastic polyps and serrated adenomas
    • Hawkins N.J., and Ward R.L. Sporadic colorectal cancers with microsatellite instability and their possible origin in hyperplastic polyps and serrated adenomas. J. Natl. Cancer Inst. 93 (2001) 1307-1313
    • (2001) J. Natl. Cancer Inst. , vol.93 , pp. 1307-1313
    • Hawkins, N.J.1    Ward, R.L.2
  • 39
    • 33751320353 scopus 로고    scopus 로고
    • Comparison of microsatellite instability, CpG island methylation phenotype, BRAF and KRAS status in serrated polyps and traditional adenomas indicates separate pathways to distinct colorectal carcinoma end points
    • O'Brien M.J., Yang S., Mack C., Xu H., Huang C.S., Mulcahy E., Amorosino M., and Farraye F.A. Comparison of microsatellite instability, CpG island methylation phenotype, BRAF and KRAS status in serrated polyps and traditional adenomas indicates separate pathways to distinct colorectal carcinoma end points. Am. J. Surg. Pathol. 30 (2006) 1491-1501
    • (2006) Am. J. Surg. Pathol. , vol.30 , pp. 1491-1501
    • O'Brien, M.J.1    Yang, S.2    Mack, C.3    Xu, H.4    Huang, C.S.5    Mulcahy, E.6    Amorosino, M.7    Farraye, F.A.8
  • 40
    • 33845608798 scopus 로고    scopus 로고
    • Classification of colorectal cancer based on correlation of clinical, morphological and molecular features
    • Jass J.R. Classification of colorectal cancer based on correlation of clinical, morphological and molecular features. Histopathology 50 (2007) 113-130
    • (2007) Histopathology , vol.50 , pp. 113-130
    • Jass, J.R.1
  • 41
    • 33745412699 scopus 로고    scopus 로고
    • Improved RT-PCR amplification for molecular analyses with long-term preserved formalin-fixed, paraffin-embedded tissue specimens
    • Hamatani K., Eguchi H., Takahashi K., Koyama K., Mukai M., Ito R., Taga M., Yasui W., and Nakachi K. Improved RT-PCR amplification for molecular analyses with long-term preserved formalin-fixed, paraffin-embedded tissue specimens. J. Histochem. Cytochem. 54 (2006) 773-780
    • (2006) J. Histochem. Cytochem. , vol.54 , pp. 773-780
    • Hamatani, K.1    Eguchi, H.2    Takahashi, K.3    Koyama, K.4    Mukai, M.5    Ito, R.6    Taga, M.7    Yasui, W.8    Nakachi, K.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.