Densely methylated MLH1 promoter correlates with decreased mRNA expression in sporadic colorectal cancers

Genes Chromosomes and Cancer

Volumn 35, Issue 1, 2002, Pages 1-10

  Furukawa, Taiji ^a   Konishi, Fumio ^b   Masubuchi, Shigehiko ^a   Shitoh, Kazuhisa ^a   Nagai, Hideo ^a   Tsukamoto, Toshihiko ^c  

^a JICHI MEDICAL UNIVERSITY   (Japan)

^b Jichi Omiya Medical Center   (Japan)

^c KITASATO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; CARRIER PROTEIN; DNA; MLH1 PROTEIN, HUMAN; NUCLEAR PROTEIN; TUMOR PROTEIN;

ADULT; AGED; ARTICLE; BINDING SITE; COLORECTAL CANCER; CORRELATION ANALYSIS; CPG ISLAND; FEMALE; GENE ISOLATION; GENE SILENCING; GENETIC ASSOCIATION; HETEROZYGOSITY LOSS; HUMAN; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; METHYLATION; MICROSATELLITE INSTABILITY; MLH1 GENE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; PROTEIN MODIFICATION; SOMATIC MUTATION; STAINING; BASE MISPAIRING; BIOSYNTHESIS; COLORECTAL TUMOR; DNA METHYLATION; DNA REPAIR; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; GENETIC TRANSCRIPTION; GENETICS; MIDDLE AGED; MOLECULAR GENETICS; MUTATION; PHENOTYPE; TRINUCLEOTIDE REPEAT;

AGED; BASE PAIR MISMATCH; BASE SEQUENCE; COLORECTAL NEOPLASMS; CPG ISLANDS; DNA METHYLATION; DNA REPAIR; DNA, NEOPLASM; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMAN; IMMUNOHISTOCHEMISTRY; LOSS OF HETEROZYGOSITY; MALE; MIDDLE AGE; MOLECULAR SEQUENCE DATA; MUTATION; NEOPLASM PROTEINS; PHENOTYPE; PROMOTER REGIONS (GENETICS); RNA, MESSENGER; SUPPORT, NON-U.S. GOV'T; TRANSCRIPTION, GENETIC; TRINUCLEOTIDE REPEAT EXPANSION; CARRIER PROTEINS; HUMANS; MIDDLE AGED; NUCLEAR PROTEINS;

EID: 0036022107     PISSN: 10452257     EISSN: None     Source Type: Journal    
DOI: 10.1002/gcc.10100     Document Type: Article

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