-
2
-
-
23444441147
-
Gene targeting using zinc finger nucleases
-
Porteus MH, Carroll D (2005) Gene targeting using zinc finger nucleases. Nat Biotechnol 23:967-973.
-
(2005)
Nat Biotechnol
, vol.23
, pp. 967-973
-
-
Porteus, M.H.1
Carroll, D.2
-
3
-
-
0028237305
-
Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells
-
Rouet P, Smih F, Jasin M (1994) Expression of a site-specific endonuclease stimulates homologous recombination in mammalian cells. Proc Natl Acad Sci USA 91:6064-6068.
-
(1994)
Proc Natl Acad Sci USA
, vol.91
, pp. 6064-6068
-
-
Rouet, P.1
Smih, F.2
Jasin, M.3
-
4
-
-
0028919608
-
Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae
-
Choulika A, Perrin A, Dujon B, Nicolas JF (1995) Induction of homologous recombination in mammalian chromosomes by using the I-SceI system of Saccharomyces cerevisiae. Mol Cell Biol 15:1968-1973.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 1968-1973
-
-
Choulika, A.1
Perrin, A.2
Dujon, B.3
Nicolas, J.F.4
-
5
-
-
0027384567
-
Homologous recombination in plant cells is enhanced by in vivo induction of double strand breaks into DNA by a site-specific endonuclease
-
Puchta H, Dujon B, Hohn B (1993) Homologous recombination in plant cells is enhanced by in vivo induction of double strand breaks into DNA by a site-specific endonuclease. Nucleic Acids Res 21:5034-5040.
-
(1993)
Nucleic Acids Res
, vol.21
, pp. 5034-5040
-
-
Puchta, H.1
Dujon, B.2
Hohn, B.3
-
6
-
-
18944373328
-
Highly efficient endogenous human gene correction using designed zinc-finger nucleases
-
Urnov FD, et al. (2005) Highly efficient endogenous human gene correction using designed zinc-finger nucleases. Nature 435:646-651.
-
(2005)
Nature
, vol.435
, pp. 646-651
-
-
Urnov, F.D.1
-
7
-
-
30344473645
-
Mammalian gene targeting with designed zinc finger nucleases
-
Porteus MH (2006) Mammalian gene targeting with designed zinc finger nucleases. Mol Ther 13:438-446.
-
(2006)
Mol Ther
, vol.13
, pp. 438-446
-
-
Porteus, M.H.1
-
8
-
-
0036021389
-
Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases
-
Bibikova M, Golic M, Golic KG, Carroll D (2002) Targeted chromosomal cleavage and mutagenesis in Drosophila using zinc-finger nucleases. Genetics 161:1169-1175.
-
(2002)
Genetics
, vol.161
, pp. 1169-1175
-
-
Bibikova, M.1
Golic, M.2
Golic, K.G.3
Carroll, D.4
-
9
-
-
33744781256
-
Efficient in toto targeted recombination in mouse liver by meganuclease-induced double-strand break
-
Gouble A, et al. (2006) Efficient in toto targeted recombination in mouse liver by meganuclease-induced double-strand break. J Gene Med 8:616-622.
-
(2006)
J Gene Med
, vol.8
, pp. 616-622
-
-
Gouble, A.1
-
11
-
-
33745278855
-
Computational redesign of endonuclease DNA binding and cleavage specificity
-
Ashworth J, et al. (2006) Computational redesign of endonuclease DNA binding and cleavage specificity. Nature 441:656-659.
-
(2006)
Nature
, vol.441
, pp. 656-659
-
-
Ashworth, J.1
-
12
-
-
33644507991
-
Directed evolution and substrate specificity profile of homing endonuclease I-SceI
-
Doyon JB, Pattanayak V, Meyer CB, Liu DR (2006) Directed evolution and substrate specificity profile of homing endonuclease I-SceI. J Am Chem Soc 128:2477-2484.
-
(2006)
J Am Chem Soc
, vol.128
, pp. 2477-2484
-
-
Doyon, J.B.1
Pattanayak, V.2
Meyer, C.B.3
Liu, D.R.4
-
13
-
-
33845914020
-
A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences
-
Smith J, et al. (2006) A combinatorial approach to create artificial homing endonucleases cleaving chosen sequences. Nucleic Acids Res 34:e149.
-
(2006)
Nucleic Acids Res
, vol.34
-
-
Smith, J.1
-
14
-
-
25144501447
-
Custom zinc-finger nucleases for use in human cells
-
Alwin S, et al. (2005) Custom zinc-finger nucleases for use in human cells. Mol Ther 12:610-617.
-
(2005)
Mol Ther
, vol.12
, pp. 610-617
-
-
Alwin, S.1
-
15
-
-
34447319080
-
An improved zinc-finger nuclease architecture for highly specific genome editing
-
Miller JC, et al. (2007) An improved zinc-finger nuclease architecture for highly specific genome editing. Nat Biotechnol 25:778-785.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 778-785
-
-
Miller, J.C.1
-
16
-
-
34447323568
-
Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases
-
Szczepek M, et al. (2007) Structure-based redesign of the dimerization interface reduces the toxicity of zinc-finger nucleases. Nat Biotechnol 25:786-793.
-
(2007)
Nat Biotechnol
, vol.25
, pp. 786-793
-
-
Szczepek, M.1
-
17
-
-
10044225983
-
Triplex-forming oligonucleotides - sequence-specific DNA ligands as tools for gene inhibition and for modulation of DNA-associated functions
-
Besch R, Giovannangeli C, Degitz K (2004) Triplex-forming oligonucleotides - sequence-specific DNA ligands as tools for gene inhibition and for modulation of DNA-associated functions. Curr Drug Targets 5:691-703.
-
(2004)
Curr Drug Targets
, vol.5
, pp. 691-703
-
-
Besch, R.1
Giovannangeli, C.2
Degitz, K.3
-
18
-
-
22144484155
-
Triplex-forming oligonucleotides as potential tools for modulation of gene expression
-
Rogers FA, Lloyd JA, Glazer PM (2005) Triplex-forming oligonucleotides as potential tools for modulation of gene expression. Curr Med Chem Anticancer Agents 5:319-326.
-
(2005)
Curr Med Chem Anticancer Agents
, vol.5
, pp. 319-326
-
-
Rogers, F.A.1
Lloyd, J.A.2
Glazer, P.M.3
-
19
-
-
33746923523
-
Triplex-stimulated intermolecular recombination at a single-copy genomic target
-
Knauert MP, Kalish JM, Hegan DC, Glazer PM (2006) Triplex-stimulated intermolecular recombination at a single-copy genomic target. Mol Ther 14:392-400.
-
(2006)
Mol Ther
, vol.14
, pp. 392-400
-
-
Knauert, M.P.1
Kalish, J.M.2
Hegan, D.C.3
Glazer, P.M.4
-
20
-
-
21244489606
-
Exploring cellular activity of locked nucleic acid-modified triplex-forming oligonucleotides and defining its molecular basis
-
Brunet E, et al. (2005) Exploring cellular activity of locked nucleic acid-modified triplex-forming oligonucleotides and defining its molecular basis. J Biol Chem 280:20076-20085.
-
(2005)
J Biol Chem
, vol.280
, pp. 20076-20085
-
-
Brunet, E.1
-
21
-
-
22844432244
-
Intercalator conjugates of pyrimidine locked nucleic acid-modified triplex-forming oligonucleotides: Improving DNA binding properties and reaching cellular activities
-
Brunet E, et al. (2005) Intercalator conjugates of pyrimidine locked nucleic acid-modified triplex-forming oligonucleotides: Improving DNA binding properties and reaching cellular activities. Nucleic Acids Res 33:4223-4234.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 4223-4234
-
-
Brunet, E.1
-
22
-
-
33750024841
-
Targeting chromosomal sites with locked nucleic acid-modified triplex-forming oligonucleotides: Study of efficiency dependence on DNA nuclear environment
-
Brunet E, Corgnali M, Cannata F, Perrouault L, Giovannangeli C (2006) Targeting chromosomal sites with locked nucleic acid-modified triplex-forming oligonucleotides: Study of efficiency dependence on DNA nuclear environment. Nucleic Acids Res 34:4546-4553.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 4546-4553
-
-
Brunet, E.1
Corgnali, M.2
Cannata, F.3
Perrouault, L.4
Giovannangeli, C.5
-
23
-
-
25644434052
-
DNA and RNA cleavage mediated by phenanthroline-cuprous oligonucleotides: From properties to applications
-
ed Zenkova MA Springer, Berlin
-
François J, Faria M, Perrin D, Giovannangeli C (2004) DNA and RNA cleavage mediated by phenanthroline-cuprous oligonucleotides: from properties to applications. Nucleic Acids and Molecular Biology - Artificial Nucleases, ed Zenkova MA (Springer, Berlin), Vol 13, pp 223-242.
-
(2004)
Nucleic Acids and Molecular Biology - Artificial Nucleases
, vol.13
, pp. 223-242
-
-
François, J.1
Faria, M.2
Perrin, D.3
Giovannangeli, C.4
-
24
-
-
0032489520
-
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
-
Rogakou EP, Pilch DR, Orr AH, Ivanova VS, Bonner WM (1998) DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139. J Biol Chem 273:5858-5868.
-
(1998)
J Biol Chem
, vol.273
, pp. 5858-5868
-
-
Rogakou, E.P.1
Pilch, D.R.2
Orr, A.H.3
Ivanova, V.S.4
Bonner, W.M.5
-
25
-
-
0032574750
-
Homology-directed repair is a major double-strand break repair pathway in mammalian cells
-
Liang F, Han M, Romanienko PJ, Jasin M (1998) Homology-directed repair is a major double-strand break repair pathway in mammalian cells. Proc Natl Acad Sci USA 95:5172-5177.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 5172-5177
-
-
Liang, F.1
Han, M.2
Romanienko, P.J.3
Jasin, M.4
-
26
-
-
33845604556
-
DNA double-strand break repair: All's well that ends well
-
Wyman C, Kanaar R (2006) DNA double-strand break repair: All's well that ends well. Annu Rev Genet 40:363-383.
-
(2006)
Annu Rev Genet
, vol.40
, pp. 363-383
-
-
Wyman, C.1
Kanaar, R.2
-
27
-
-
0028088766
-
Single base-pair deletions induced by bleomycin at potential double-strand cleavage sites in the aprt gene of stationary phase Chinese hamster ovary D422 cells
-
Povirk LF, Bennett RA, Wang P, Swerdlow PS, Austin MJ (1994) Single base-pair deletions induced by bleomycin at potential double-strand cleavage sites in the aprt gene of stationary phase Chinese hamster ovary D422 cells. J Mol Biol 243:216-226.
-
(1994)
J Mol Biol
, vol.243
, pp. 216-226
-
-
Povirk, L.F.1
Bennett, R.A.2
Wang, P.3
Swerdlow, P.S.4
Austin, M.J.5
-
28
-
-
0035917489
-
Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency
-
Moshous D, et al. (2001) Artemis, a novel DNA double-strand break repair/V(D)J recombination protein, is mutated in human severe combined immune deficiency. Cell 105:177-186.
-
(2001)
Cell
, vol.105
, pp. 177-186
-
-
Moshous, D.1
-
29
-
-
33646130853
-
Requirement for SWI/SNF chromatin-remodeling complex in Tat-mediated activation of the HIV-1 promoter
-
Treand C, et al. (2006) Requirement for SWI/SNF chromatin-remodeling complex in Tat-mediated activation of the HIV-1 promoter. EMBO J 25:1690-1699.
-
(2006)
EMBO J
, vol.25
, pp. 1690-1699
-
-
Treand, C.1
-
30
-
-
22444445110
-
Stable transmission of targeted gene modification using single-stranded oligonucleotides with flanking LNAs
-
Andrieu-Soler C, et al. (2005) Stable transmission of targeted gene modification using single-stranded oligonucleotides with flanking LNAs. Nucleic Acids Res 33:3733-3742.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 3733-3742
-
-
Andrieu-Soler, C.1
-
31
-
-
33846211894
-
High-affinity triplex-forming oligonucleotide target sequences in mammalian genomes
-
Wu Q, et al. (2007) High-affinity triplex-forming oligonucleotide target sequences in mammalian genomes. Mol Carcinog 46:15-23.
-
(2007)
Mol Carcinog
, vol.46
, pp. 15-23
-
-
Wu, Q.1
-
32
-
-
38049093008
-
Site-directed gene mutation at mixed sequence targets by psoralen-conjugated pseudo-complementary peptide nucleic acids
-
Kim KH, Nielsen PE, Glazer PM (2007) Site-directed gene mutation at mixed sequence targets by psoralen-conjugated pseudo-complementary peptide nucleic acids. Nucleic Acids Res 35:7604-7613.
-
(2007)
Nucleic Acids Res
, vol.35
, pp. 7604-7613
-
-
Kim, K.H.1
Nielsen, P.E.2
Glazer, P.M.3
-
33
-
-
22144446030
-
Programmable DNA binding oligomers for control of transcription
-
Dervan PB, Doss RM (2005) Programmable DNA binding oligomers for control of transcription. Curr Med Chem Anti Cancer Agents 5:373-387.
-
(2005)
Curr Med Chem Anti Cancer Agents
, vol.5
, pp. 373-387
-
-
Dervan, P.B.1
Doss, R.M.2
-
34
-
-
0026323540
-
Nuclease activity of 1,10-phenanthroline-copper in study of protein-DNA interactions
-
Sigman DS, Kuwabara MD, Chen CH, Bruice TW (1991) Nuclease activity of 1,10-phenanthroline-copper in study of protein-DNA interactions. Methods Enzymol 208:414-433.
-
(1991)
Methods Enzymol
, vol.208
, pp. 414-433
-
-
Sigman, D.S.1
Kuwabara, M.D.2
Chen, C.H.3
Bruice, T.W.4
-
35
-
-
0035853082
-
Delivery of proteins into living cells by reversible membrane permeabilization with streptolysin-O
-
Walev I, et al. (2001) Delivery of proteins into living cells by reversible membrane permeabilization with streptolysin-O. Proc Natl Acad Sci USA 98:3185-3190.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3185-3190
-
-
Walev, I.1
|