Intercalator conjugates of pyrimidine locked nucleic acid-modified triplex-forming oligonucleotides: Improving DNA binding properties and reaching cellular activities

Nucleic Acids Research

Volumn 33, Issue 13, 2005, Pages 4223-4234

  Brunet, Erika ^a   Corgnali, Maddalena ^b   Perrouault, Loïc ^a   Roig, Victoria ^c   Asseline, Ulysse ^c   Sørensen, Mads D ^d   Babu, B Ravindra ^d   Wengel, Jesper ^d   Giovannangeli, Carine ^a  

^a MUSÉUM NATIONAL D'HISTOIRE NATURELLE   (France)

^b UNIVERSITY OF UDINE   (Italy)

^c CENTRE DE BIOPHYSIQUE MOLÉCULAIRE   (France)

^d UNIVERSITY OF SOUTHERN DENMARK   (Denmark)

Author keywords

[No Author keywords available]

Indexed keywords

OLIGONUCLEOTIDE; PYRIMIDINE LOCKED NUCLEIC ACID TRIPLEX FORMING OLIGONUCLEOTIDE; UNCLASSIFIED DRUG; ANTISENSE OLIGONUCLEOTIDE; DNA; DNA BINDING PROTEIN; INTERCALATING AGENT; LOCKED NUCLEIC ACID; PYRIMIDINE DERIVATIVE; TRIPLEX DNA;

5' UNTRANSLATED REGION; ARTICLE; CELL ACTIVITY; CELL CULTURE; CONJUGATION; CONTROLLED STUDY; DNA METABOLISM; EQUILIBRIUM CONSTANT; GENE TARGETING; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERCALATION COMPLEX; MOLECULAR DYNAMICS; PH; PRIORITY JOURNAL; PROTEIN DNA BINDING; PROTEIN FUNCTION; PROTEIN STABILITY; RNA ANALYSIS; SURFACE PLASMON RESONANCE; ULTRAVIOLET SPECTROSCOPY; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; GENETIC TRANSCRIPTION; METABOLISM;

DNA; DNA-BINDING PROTEINS; HELA CELLS; HUMANS; HYDROGEN-ION CONCENTRATION; INTERCALATING AGENTS; OLIGONUCLEOTIDES, ANTISENSE; PYRIMIDINES; TRANSCRIPTION, GENETIC;

EID: 22844432244     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gki726     Document Type: Article

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