Decreased glutathione results in calcium-mediated cell death in PC12

Free Radical Biology and Medicine

Volumn 23, Issue 7, 1997, Pages 1055-1066

  Jurma, Octavian P ^a   Hom, Denise G ^a   Andersen, Julie K ^a  

^a UNIVERSITY OF SOUTHERN CALIFORNIA   (United States)

Author keywords

Calcium homeostasis; Glutathione; Membrane depolarization; Na+ K+ ATPase; Oxidative stress; Parkinson's disease; PC12

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); CALBINDIN; GLUTATHIONE; GLUTATHIONE SYNTHASE; OLIGOMER;

ANIMAL CELL; ARTICLE; CALCIUM HOMEOSTASIS; CELL DEATH; CELL FREE SYSTEM; DEPOLARIZATION; DOPAMINERGIC NERVE CELL; NERVE CELL LESION; NONHUMAN; OPEN READING FRAME; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; RAT;

ANIMALS; BINDING SITES; CALCIUM; CELL DEATH; DISEASE MODELS, ANIMAL; DOPAMINE; DOWN-REGULATION; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; NEURONS; OLIGONUCLEOTIDES, ANTISENSE; OPEN READING FRAMES; PARKINSON DISEASE; PC12 CELLS; RATS; REACTIVE OXYGEN SPECIES;

EID: 0030775042     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(97)00134-2     Document Type: Article

References (76)

1. 2+ homeostasis and cell death. J. Neurosci. 15:1995;6239-6249.
2. Hall E. D., Pazara K. E., Braughler J. M. Effects of tirilizad mesylate on post-ischemic brain lipid peroxidation and recovery of extracellular calcium in gerbils. Stroke. 22:1991;361-366.
3. Siesjo B. K., Zhao Q., Pahlmark K., Siesjo P., Katsura K., Folbergrova J. Glutamate, calcium, and free radicals as mediators of ischemic brain damage. Ann. Thorac. Surg. 59:1995;1316-1320.
4. 2+ transport by free oxygen radicals in vitro. Biochem. Biophys. Res. Commun. 199:1994;63-69.
5. Hirsch E. C. Why are catecholaminergic neurons more vulnerable than other cells in Parkinson's disease. Ann. Neurol. 32:1992;S88-S93.
6. Cohen G. Monoamine oxidase, hydrogen peroxide, and Parkinson's disease. Adv. Neurol. 45:1986;119-125.
7. Halliwell B., Gutteridge J. M. C. Oxygen radicals and the nervous system. Trends Neurosci. 8:1985;22-26.
8. Olanow C. W. A radical hypothesis for neurodegeneration. Trends Neurosci. 16:1983;439-444.
9. Bannon M. J., Goedert M., Wolff O. H. The possible relationship of glutathione, melanin, and 1-methyl-4-phenyl-tetrahydropyridine (MPTP) to Parkinson's disease. Biochem. Pharmacol. 33:1984;2697-2698.
10. Perry T. L., Godin D. V., Hansen S. Parkinson's disease: A disorder due to nigral glutathione deficiency? Neurosci. Lett. 33:1982;305-310.
11. Kish S. J., Morito C., Hornykiewicz O. Glutathione peroxidase activity in Parkinson's disease. Neurosci. Lett. 58:1985;343-346.
12. Ambani L. M., Van Woert M. H., Murphy S. Brain peroxidase and catalase in Parkinson disease. Arch. Neurol. 32:1975;114-118.
13. Dexter D. T., Carter C. J., Wells F. R., Javoy-Agid F., Agid Y., Lees A., Jenner P., Marsden C. D. Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease. J. Neurochem. 52:1989;381-389.
14. Dexter D. T., Holley A. E., Flitter W. D. Increased levels of hydroperoxides in the Parkinsonian substantia nigra: An HPLC and ESR study. Mov. Dis. 9:1994;92-97.
15. Sanchez-Ramos J. R., Overvik E., Ames B. N. A marker of oxyradical-mediated DNA damage (8-hydroxy-2′ deoxyguanosine) is increased in nigrostriatum of Parkinson's disease brain. Neurodegeneration. 3:1994;197-204.
16. Olanow C. W. A scientific rationale for neurodegeneration. J. Neural Transm. 91:1993;161-180.
17. Andersen J. K., Mo J.-Q., Koek L. L., Hom D. G., McNeill T. H. Effects of buthionine sulfoximide, a synthesis inhibitor of the antioxidant glutathione, on murine nigrostriatal neurons. J. Neurochem. 67:1996;2164-2171.
18. Felten D. L., Felten S. Y., Fuller R. W., Romano T. D., Barry-Smalstig E., Wong D. T., Clemens J. A. Chronic dietary pergolide preserves nigrostriatal integrity in aged F344 rats. Neurobiol. Aging. 13:1992;339-351.
19. McNeill T. H., Koek L. L., Haycock J. W. Age-correlated changes in dopaminergic nigrostriatal perikarya of the C57BL/6NNi mouse. Mech. Ageing Dev. 24:1984;293-307.
20. Greene L. A., Tischler A. S. Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc. Natl. Acad. Sci. USA. 73:1976;2424-2428.
21. Rudy B., Kirschenbaum B., Greene L. A. Nerve growth factor-induced increase in saxiton binding to rat PC12 pheochromocytoma cells. J. Neurosci. 2:1982;1405-1411.
22. Greene L. A., Burstein D. E., Black M. M. The role of transcription-dependent priming in growth factor promoted neurite outgrowth. Dev. Biol. 91:1982;305-316.
23. Subban E. L., Goldstein M., Greene L. A. Regulation of the multiple forms of dopamine beta-hydroxylase by nerve growth factor, dexamethasone, and dibutyryl cyclic AMP in the PC12 pheochromocytoma cell line. J. Biol. Chem. 258:1982;7819-7823.
24. Ferrari G., Yan C. Y., Greene L. A. N-acetylcysteine (D- and L-stereoisomers) prevents apoptotic cell death of neuronal cells. J. Neurosci. 15:1995;2857-2866.
25. Faranelli S. E., Park D. S., Greene L. A. Nitric oxide delays the death of trophic factor deprived PC12 cells and sympathetic neurons by a cGMP-mediated mechanism. J. Neurosci. 16:1996;2325-2334.
26. Hynes M. A., Poulsen K., Armanini M., Berkemeier L., Phillips H., Rosenthal A. Neurotrophin 4/5 is a survival factor for embryonic midbrain dopaminergic neurons in enriched cultures. J. Neurosci. Res. 37:1994;144-154.
27. Pan Z., Perez-Polo R. Role of nerve growth factor in oxidant homeostasis: Glutathione metabolism. J. Neurochem. 61:1993;1713-1721.
28. Troy C. M., Greene L. A., Shelanski M. L. Neurite outgrowth in peripherin-depleted PC12 cells. J. Cell. Biol. 117:1992;1085-1092.
29. Jap Tjoen San E., Schmidt-Michels, Oestereicher A. B., Gispen W. H., Schotsman P. Inhibition of nerve growth factor-induced B-50/GAP 43 expression by antisense oligomers interferes with neurite outgrowth of PC12 cells. Biochem. Biophys. Res. Commun. 187:1992;839-846.
30. Troy C. M., Shelanski M. L. Down-regulation of copper/zince superoxide dismutase causes apoptotic death in PC12 neuronal cells. Proc. Natl. Acad. Sci. USA. 91:1994;6384-6387.
31. Narayanan R., Higgins K. A., Perez J. R., Coleman T. A., Rosen C. A. Evidence for different functions of the p50 and p65 subunits of NF-kappa B with a cell adhesion model. Mol. Cell. Biol. 13:1993;3802-3810.
32. Brugge B., Reddy D., Matus A. Attenuation of microtubule-associated protein 1B expression by antisense oligonucleotides inhibits initiation of neurite outgrowth. Neuroscience. 52:1993;489-496.
33. Osen-Sand A., Catsicas M., Staple J. K., Jones K. A., Ayala G., Knowles J., Grenningloh G., Catsicas S. Inhibition of axonal growth by SNAP-25 antisense oligonucleotides in vitro and in vivo. Nature. 364:1993;445-448.
34. Huang C. S., Chang L.-S., Anderson M. E., Meister A. Catalytic and regulatory properties of the heavy chain subunit of rat kidney gamma-glutamylcysteine synthetase. J. Biol. Chem. 26:1993;19675-19680.
35. Chirgwin J. M., Przybyla A. E., MacDonald R. J., Rutter W. J. Isolation of biologically active ribonucleic acids from sources enriched in ribonuclease. Biochemistry. 18:1979;5294-5299.
36. Feinberg A. P., Vogelstein B. A technique for radiolabeling DNA restriction fragments to high specific activity. Biochemistry. 137:1984;266-269.
37. Seelig G. F., Meister A. Glutathione biosynthesis: Gamma-glutamylcysteine synthetase from rat kidney. Methods Enzymol. 113:1985;379-390.
38. Tietze F. Enzymatic methods for quantitative determination of nanogram amounts of total and oxidized glutathione: Application to mammalian blood and other tissue. Anal. Biochem. 27:1969;502-522.
39. Behl C., Davis J. B., Lesley R., Schubert D. Hydrogen peroxide mediates beta amyloid protein toxicity. Cell. 77:1994;817-827.
40. Minta A., Kao J. P., Tsien R. Y. Fluorescent indicators for cytosolic calcium based on rhodamine and fluorescein chromophores. J. Biol. Chem. 264:1989;8171-8178.
41. Wilber K. M., Bernheim F., Shapiro O. W. The thiobarbituric acid test for the oxidation of unsaturated fatty acids by various agents. Arch. Biochem. Biophys. 24:1949;303-313.
42. Levine R. L., Garland D., Oliver C. N., Amici A., Climent I., Lenz A. G., Ahn B. W., Shaltiel S., Stadtman E. R. Determination of carbonyl content in oxidatively modified proteins. Methods Enzymol. 186:1990;464-478.
43. Andersen J. K., Zhang M. B., Zhong X. H., Rosenberg Y. Y., Howard B. D. 1-Methyl-4-phenylhydropyridine resistant flat PC12 variants have a partial loss of transformed phenotype. J. Neurochem. 55:1990;559-567.
44. Rausch W., Hirata Y., Nagatsu T., Reiderer P., Jellinger K. Tyrosine hydroxylase activity in caudate nucleus from Parkinson's brain: effects of iron and phosphorylating agents. J. Neurochem. 50:1988;202-208.
45. Koh J. Y., Choi D. W. Quantitative determination of glutamate-mediated corticol neuronal injury in cell culture by lactate dehydrogenase efflux assay. J. Neurochem. Methods. 20:1987;83-90.
46. Hansen M. B., Nielson S. E., Berg K. Re-examination and further development of precise and rapid dye method for measuring cell growth/cell killing. J. Immunol. Methods. 119:1989;203-210.
47. Rohn, T. T.; Hinds, T. R.; Vincenzi, F. F. Ion transport ATPases as targets for free radical damage. Biochem. Pharmacol. 46:535-534; 1993.
48. Yan N., Meister A. Amino acid sequence of rat kidney gamma-glutamylcysteine synthetase. J. Biol. Chem. 265:1990;1588-1593.
49. Gipp J. J., Chang C., Mulcahy R. T. Cloning and nucleotide sequencing of a full-length cDNA for human liver gamma glutamylcysteine synthetase. Biochem. Biophys. Res. Commun. 185:1992;29-35.
50. Levy E. J., Anderson M. E., Meister A. Transport of glutathione diethylester into human cells. Proc. Natl. Acad. Sci. USA. 90:1990;9171-9175.
51. Offen D., Ziv I., Sternin H., Melamed E., Hochman A. Prevention of dopamine-induced cell death by thiol antioxidants: Possible implications for treatment of Parkinson's disease. Exp. Neurol. 141:1996;32-39.
52. Wei Q., Hom D. G., Andersen J. K. Genetic elevation of monoamine oxidase levels in dopaminergic PC12 cells results in increased free radical damage and sensitivity to MPTP. J. Neurosci. Res. 46:1996;666-673.
53. Kubo T., Enokido Y., Yamada M., Oka T., Uchiyama Y., Hatanaka H. Oxygen-induced apoptosis in PC12 cells with special reference to the role of Bcl-2. Brain Res. 733:1996;175-183.
54. Zhou Y., Gopalakrishnan V., Richardson J. S. Action of neurotoxic beta-amyloid on calcium homeostasis and viability of PC12 cells are blocked by antioxidants but not by calcium channel antagonists. J. Neurochem. 67:1996;1419-1425.
55. Kasabdji D., Shanmugam V., Rathinavelu A. Effect of cisplatin on dopamine release from PC12 cells. Life Sci. 59:1996;1793-1801.
56. 2+-induced cytotoxicity in PC12 cells. J. Neurochem. 63:1994;895-902.
57. Beal M. F. Aging, energy, and oxidative stress in neurodegenerative disease. Ann. Neurol. 38:1995;357-366.
58. Mattson M. P., Goodman Y. Different amyloidogenic peptides share a similar mechanism of neurotoxicity involving reactive oxygen species and calcium. Brain Res. 676:1995;219-224.
59. Lees G. J., Lehmann A., Sandberg M., Hamberger A. The neurotoxicity of ouabain, a sodium-potassium ATPase inhibitor, in the rat hippocampus. Neurosci. Lett. 120:1990;159-162.
60. 2+ ATPase and some soluble enzymes related to energy metabolism in brains of patients with Alzheimer's disease. Neurosci. Lett. 112:1990;338-342.
61. Kaneko M., Matsumoto Y., Hayashi H., Kobayashi A., Yamazaki N. Oxygen free radicals and calcium homeostasis in the heart. Mol. Cell. Biochem. 139:1994;91-100.
62. Clague J. R., Langer G. A. The pathogenesis of free-radical induced calcium leak in cultured rat cardiomyocytes. J. Mol. Cell. Cardiol. 26:1994;11-21.
63. + pump current in isolated rabbit ventricular myocytes using the whole cell voltage clamp technique. Circ. Res. 72:1993;91-101.
64. Hinshaw D. B., Miller M. T., Omann G. M., Beal T. F., Hyslop P. A. A cellular model of oxidant-mediated neuronal injury. Brain Res. 615:1993;13-26.
65. Orrenius S., Nicotera P. The calcium ion and cell death. J. Neural Transm. 43:1994;1-11.
66. Nicotera P., Bellomo G., Orrenius S. Calcium-mediated mechanisms in chemically induced cell death. Annu. Rev. Pharmacol. Toxicol. 32:1992;449-470.
67. Zhang J., Dawson V. L., Dawson T. M., Snyder S. M. Nitric oxide activation of poly (ADP-ribose) synthetase in neurotoxicity. Science. 263:1994;687-689.
68. Darley-Usmar V., Wiseman H., Halliwell B. Nitric oxide and oxygen radicals: A question of balance. FEBS Lett. 369:1995;131-135.
69. Ischiropoulos H., Zhu L., Chen J., Tsai M., Martin J. C., Smith C. D., Beckman J. S. Peroxynitrite-mediated tyrosine nitration catalyzed by superoxide dismutase. Arch. Biochem. Biophys. 298:1995;431-437.
70. Malis C. D., Bonventre J. V. Mechanism of calcium potentiation of oxygen free radical injury to renal mitochondria. A model for post-ischemic and toxic mitochondria damage. J. Biol. Chem. 261:1986;14201-14208.
71. Jenner P. D., Schapira A. H. V., Marsden C. D. Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disorder. Neurology. 42:1992;2241-2250.
72. Yamada T., McGeer P. L., Baimbridge K. G., McGeer E. Relative sparing in Parkinson's disease of substantia nigra dopamine neurons containing calbindin-D28K. Brain Res. 526:1990;303-307.
73. Favaron M., Manev H., Siman R., Bertolino M., Szekely A. M., De Erasqausquin G. A., Guidotti A., Costa E. Down regulation of protein kinase C protects cerebellar granule cells in primary culture from glutamate-induced toxicity. Proc. Natl. Acad. Sci. USA. 87:1990;1983-1987.
74. Gupta M., Schwartz J., Chen X. L., Roisen F. J. Gangliosides prevent MPTP toxicity in mice - An immunological study. Brain Res. 527:1990;330-334.
75. 2+ homeostasis in cultures of embryonic dopaminergic neurons. Mol. Brain Res. 21:1994;303-311.
76. + toxicity by NMDA antagonists. Nature. 349:1991;414-418.