Competitive inhibitors of Helicobacter pylori type II dehydroquinase: Synthesis, biological evaluation, and NMR studies

ChemMedChem

Volumn 3, Issue 5, 2008, Pages 756-770

  Sánchez Sixto, Cristina ^a   Prazeres, Verónica F V ^a   Castedo, Luis ^a   Suh, Se Won ^b   Lamb, Heather ^c   Hawkins, Alastair R ^c   Cañada, Francisco Javier ^d   Jiménez Barbero, Jesús ^d   González Bello, Concepción ^a  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b Seoul National University   (South Korea)

^c NEWCASTLE UNIVERSITY   (United Kingdom)

^d CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

Author keywords

Competitive; Dehydroquinase; Helicobacter pylori; Inhibitors; Saturation transfer difference

Indexed keywords

3 DEHYDROQUINATE DEHYDRATASE; 3-DEHYDROQUINATE DEHYDRATASE; ANTIINFECTIVE AGENT; ENZYME INHIBITOR; HYDROLYASE;

ARTICLE; BINDING COMPETITION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; HELICOBACTER PYLORI; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; STRUCTURE ACTIVITY RELATION; SYNTHESIS;

ANTI-BACTERIAL AGENTS; BINDING, COMPETITIVE; ENZYME INHIBITORS; HELICOBACTER PYLORI; HYDRO-LYASES; MAGNETIC RESONANCE SPECTROSCOPY; MODELS, MOLECULAR; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 47649120747     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.200700307     Document Type: Article

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