Second-generation mimics of ganglioside GM1 oligosaccharide: A three-dimensional view of their interactions with bacterial enterotoxins by NMR and computational methods

Chemistry - A European Journal

Volumn 8, Issue 20, 2002, Pages 4597-4612

  Bernardi, Anna ^a   Potenza, Donatella ^a   Capelli, Anna Maria ^b   García Herrero, Alicia ^c   Cañada, F Javier ^c   Jiménez Barbero, Jesús ^c  

^a UNIVERSITY OF MILAN   (Italy)

^b GSK   (Italy)

^c CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

Author keywords

Carbohydrate protein interactions; Carbohydrates; Cholera toxin; Glycomimetics; NMR spectroscopy

Indexed keywords

BACTERIA; COMPUTER SIMULATION; HYDROPHOBICITY; NUCLEAR MAGNETIC RESONANCE; SACCHARIFICATION;

CHOLERA TOXIN (CT); LIGAND AFFINITY;

ORGANIC COMPOUNDS;

CARBOHYDRATE; CHOLERA TOXIN; ENTEROTOXIN; GANGLIOSIDE GM1; HYDROXYACID; ISOLEUCINE; LACTIC ACID DERIVATIVE; LIGAND; LYSINE; OLIGOSACCHARIDE; SIALIC ACID;

ARTICLE; BINDING AFFINITY; BINDING SITE; COMPLEX FORMATION; COMPUTER MODEL; CONFORMATION; HYDROPHOBICITY; MATHEMATICAL ANALYSIS; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; NUCLEAR OVERHAUSER EFFECT; PROTEIN INTERACTION;

EID: 0037131439     PISSN: 09476539     EISSN: None     Source Type: Journal    
DOI: 10.1002/1521-3765(20021018)8:20<4597::AID-CHEM4597>3.0.CO;2-U     Document Type: Article

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