Characterization of the interaction between Aβ 1-42 and glyceraldehyde phosphodehydrogenase

Journal of Peptide Science

Volumn 14, Issue 6, 2008, Pages 755-762

  Verdier, Yann ^a,b   Földi, István ^a   Sergeant, Nicolas ^c   Fülöp, Lívia ^a   Penke, Zsüzs ^a,d   Janáky, Tamás ^a,e   Szücs, Mária ^f   Penke, Botond ^a,f  

^a UNIVERSITY OF SZEGED   (Hungary)

^b PSL RESEARCH UNIVERSITY   (France)

^c JEAN PIERRE AUBERT RESEARCH CENTER   (France)

^d UMR 8620   (France)

^e INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^f INSTITUTE OF BIOCHEMISTRY   (Hungary)

Author keywords

Alzheimer's disease; Beta amyloid peptide; Binding protein; Coprecipitation assay; GAPDH

Indexed keywords

AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; SYNTHETIC PEPTIDE; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN (1 42); AMYLOID BETA-PROTEIN (1-42); PEPTIDE FRAGMENT;

ALZHEIMER DISEASE; AMINO ACID SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BRAIN MITOCHONDRION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME BINDING; ENZYME LOCALIZATION; MALE; NONHUMAN; PATHOPHYSIOLOGY; PRECIPITATION; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; PROTEIN PURIFICATION; RAT; SEQUENCE ANALYSIS; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING; CELL FRACTIONATION; CHEMISTRY; ENZYMOLOGY; METABOLISM; MOLECULAR GENETICS; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN BINDING;

RATTUS;

AMINO ACID SEQUENCE; AMYLOID BETA-PROTEIN; ELECTROPHORESIS, POLYACRYLAMIDE GEL; GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASES; MOLECULAR SEQUENCE DATA; PEPTIDE FRAGMENTS; PROTEIN BINDING; SUBCELLULAR FRACTIONS;

EID: 47249104380     PISSN: 10752617     EISSN: 10991387     Source Type: Journal    
DOI: 10.1002/psc.998     Document Type: Article

References (53)

1. Bückig A, Tikkanen R, Herzog V, Schmitz A. Cytosolic and nuclear aggregation of the amyloid beta-peptide following its expression in the endoplasmic reticnlum. Histochem. Cell Biol. 2002; 118: 353-360.
2. Wirths O, Multhaup G, Bazer TA. A modified β-amyloid peptide-the first step of a fatal cascade. J. Neurochem. 2004; 91: 513-520.
3. Ling Y, Morgan K, Kalsheker N. Amyloid precursor protein (APP) and the biology of proteolytic processing: relevance to Alzheimer's disease. Int. J. Biochem. Cell Biol. 2003; 35: 1505-1535.
4. Verdier Y, Penke B. Polypeptide and protein aggregates with neurotoxic properties in Neuro-degenerative disorders: emphasis on beta-amyloid-induced dysfunction of receptor-mediated signal transduction pathways. Curr. Signal Trans. Ther. 2006; 1: 97-112.
5. Verdier Y, Zarandi M, Penke B. Amyloid beta-peptide interactions with neuronal and glial cell plasma membrane: binding sites and implications for Alzheimer's disease. J. Pept. Sci. 2004; 10: 229-248.
6. Tuppo EE, Arias HR. The role of inflammation in Alzheimer's disease. Int. J. Biochem. Cell Biol. 2005; 37: 289-305.
7. Selkoe DJ. Alzheimer's disease is a synaptic failure. Science 2002; 298: 789-791.
8. Walsh DM, Selkoe DJ. Aβ oligomers- a decade of discovery. J. Neurochem. 2007; 101: 1172-1184.
9. Dickson DW. Apoptotic mechanisms in Alzheimer neurofibrillary degeneration: cause or effect? J. Clin. Invest. 2004; 114: 23-27.
10. Yuan J, Yankner BA. Apoptosis in the nervous system. Nature 2000; 407: 802-809.
11. Hartmann T, Bieger SC, Bruhl B, Tienari PJ, Ida N, Allsop D, Roberts GW, Masters CL, Dotti CG, Unsicker K, Beyreuther K. Distinct sites of intracellular production for Alzheimer's disease A beta40/42 amyloid peptides. Nat. Med. 1997; 3: 1016-1020.
12. Xu H, Sweeney D, Wang R, Thinakaran G, Lo AC, Sisodia SS, Greengard P, Gandy S. Generation of Alzheimer beta-amyloid protein in the trans-Golgi network in the apparent absence of vesicle formation. Proc. Natl. Acad. Sci. U.S.A. 1997; 94: 3748-3752.
13. Koo EH, Squazzo SL. Evidence that production and release of amyloid beta-protein involves the endocytic pathway. J. Biol. Chem. 1994; 269: 17386-17389.
14. Walsh DM, Tseng BP, Rydel RE, Podlisny MB, Selkoe DJ. The oligomerization of amyloid beta-protein begins intracellularly in cells derived from human brain. Biochemistry 2000; 39: 10831-10839.
15. Yan SD, Stern DM. Mitochondrial dysfunction and Alzheimer's disease: role of amiloid-β peptide alcohol dehydrogenas (ABAD). Int. J. Exp. Pathol. 2005; 86: 161-171.
16. Parihar MS, Brewer GJ. Mitoenergetic failure in Alzheimer disease. Am. J. Physiol. Cell Physiol. 2007; 292: 8-23.
17. Norenberg MD, Rao KV. The mitochondrial permeability in neurologic disease. Neurochem. Int. 2007; 50: 983-997.
18. Chan PH, Mitochondria and neuronal death/survival signaling pathways in cerebral ischemia. Neurochem. Res. 2005; 29: 1943-1949.
19. Verdier Y, Huszar E, Penke B, Penke Z, Woffendin G, Scigelova M, Fulop L, Szucs M, Medzihradszky K, Janaky T. Identification of synaptic plasma membrane proteins co-precipitated with fibrillar beta-amyloid peptide. J. Neurochem. 2005; 94: 617-628.
20. Berry MD. Glyceraldehyde-3-phosphate dehydrogenase as a target for small-molecule disease-modifying therapies in human neurodegenerative disorders. J. Psychiatry Neurosci. 2004; 29: 337-345.
21. Sirover MA. New insights into an old protein: the functional diversity of mammalian glyceraldehyde-3-phosphate dehydrogenase. Biochim. Biophys. Acta 1999; 1432: 159-184.
22. Mazzola JL, Sirover MA. Alteration of intracellular structure and function of glyceraldehyde-3-phosphate dehydrogenase: a common phenotype of neurodegenerative disorders? Neurotoxicology 2002; 23: 603-609.
23. Chuang DM, Hough C, Senatorov VV. Glyceraldehyde-3-phosphate dehydrogenase, apoptosis, and neurodegenerative diseases. Annu, Rev. Pharmacol. Toxicol. 2005; 45: 269-290.
24. Saunders PA, Chen RW, Chuang DM. Nuclear translocation of glyceraldehyde-3-phosphate dehydrogenase isoforms during neuronal apoptosis. J. Neurochem. 1999; 72: 925-932.
25. Schulze H, Schuler A, Stuber D, Dobeli H, Langen H, Huber G. Rat brain glyceraldehyde-3-phosphate dehydrogenase interacts with the recombinant cytoplasmic domain of Alzheimer's beta-amyloid precursor protein. J. Neurochem. 1993; 60: 1915-1922.
26. Oyama R, Yamamoto H, Titani K. Glutamine synthetase, hemoglobin alpha-chain, and macrophage migration inhibitory factor binding to amyloid beta-protein: their identification in rat brain by a novel affinity chromatography and in Alzheimer's disease brain by immunoprecipitationa. Biochim. Biophys. Acta 2000; 1479: 91-102.
27. Zarándi M, Soos K, Fülöp L, Bozsó ZS, Datki ZS, Tóth GK, Penke B. Synthesis of Ab(1-42) and its derivatives with improved efficiency. J. Pept, Sci. 2007; 13: 94-99.
28. Fabian G, Bozo B, Szikszay M, Horvath G, Coscia CJ, Szücs M. Chronic morphine-induced changes in mu-opioid receptors and G proteins of different subcellular loci in rat brain. J. Pharmacol. Exp. Ther. 2002; 302: 774-780.
29. Lorenzo A, Yuan M, Zhang Z, Paganetti PA, Sturchler-Pierrat C, Staufenbiel M, Mautino J, Vigo FS, Sommer B, Yankner BA. Amyloid beta interacts with the amyloid precursor protein: a potential toxic mechanism in Alzheimer's disease. Nat. Neurosci. 2000; 3: 460-464.
30. Ahramoff MD, Magelhaes PJ. Ram SJ. Image processing with imageJ. Biophot. Internat. 2004; 11: 36-42.
31. Chander H, Chauhan A, Wegiel J, Malik M. Sheikh A, Chauhan V. Binding of trypsin to fibrillar amyloid beta-protein. Brain Res. 2006; 1082: 173-181.
32. Cumming RC, Schubert D. Amyloid-beta induces disulfide bonding and aggregation of GAPDH in Alzheimer's disease. FASEB J. 2005; 19: 2060-2062.
33. Soderberg L, Kakuyama H, Moller A, Ito A, Winblad B, Tjernberg LO, Naslund J. Characterization of the Alzheimer's disease-associated CLAC protein and identification of an amyloid beta-peptide-binding site. J. Biol. Chem. 2005; 280:1007-1015.
34. Johansson AS, Berglind-Dehlin F, Karlsson G, Edwards K, Gellerfors P, Lannfelt L. Physiochemical characterization of the Alzheimer's disease-related peptides A beta 1-42Arctic and A beta 1-42wt. FEBS J. 2006; 273: 2618-2630.
35. Pike CJ, Walencewicz AJ, Glabe CG, Cotman CW. Aggregation-related toxicity of synthetic beta-amyloid protein in hippocampal cultures. Eur. J. Pharmacol. 1991; 207: 367-368.
36. Jarrett JT, Berger EP, Lansbury PT Jr. The carboxy terminus of the beta amyloid protein is critical for the seeding of amyloid formation: implications for the pathogenesis of Alzheimer's disease. Biochemistry 1993; 32: 4693-4697.
37. Olofsson A, Lindhagen-Persson M, Sauer-Eriksson AE, Ohman A. Amide solvent protection analysis demonstrates that amyloid-beta(1-40) and amyloid-beta(1-42) form different fibrillar structures under identical conditions. Biochem. J. 2007; 404: 63-70.
38. Stevens SM, Zharikova AD, Prokai L. Proteomic analysis of the synaptic plasma membrane fraction isolated from rat forebrain. Brain Res. Mol. Brain Res. 2003; 117:116-128.
39. Tisdale EJ. Glyceraldehyde-3-phosphate dehydrogenase is required for vesicular transport in the early secretory pathway. J. Biol. Chem. 2001; 276: 2480-2486.
40. Lovell MA, Xiong S, Markesbery WR, Lynn BC. Quantitative proteomic analysis of mitochondria from primary neuron cultures treated with amyloid beta peptide. Neurochem. Res. 2005; 30: 113-122.
41. Lustbader JW, Cirilli M, Lin C, Xu HM, Takuma K, Wang N, Caspersen C, Chen X, Pollak S. Chancy M, Trinchese F, Liu S, Gunn-Moore F, Lue LF, Walker DG, Kuppusamy P, Zewier ZL, Arancio O, Stern D, Yan SS, Wu H. ABAD directly links Abeta to mitochondrial toxicity in Alzheimer's disease. Science 2004; 304: 448-452.
42. Mazzola JL, Sirover MA. Subcellular alteration of glyceraldehyde-3-phosphate dehydrogenase in Alzheimer's disease fibroblasts. J. Neurosci. Res. 2003; 71: 279-285.
43. Bae BI, Hara MR, Cascio MB, Wellington CL, Hayden MR, Ross CA, Ha HC, Li XJ, Snyder SH, Sawa A. Mutant huntingtin: nuclear translocation and cytotoxicity mediated by GAPDH. Proc. Natl. Acad. Sci. U. S. A. 2006; 103: 3405-3409.
44. Wang Q, Woltjer RL, Cimino PJ, Pan C, Montine KS, Zhang J, Montine TJ. Proteomic analysis of neurofibrillary tangles in Alzheimer disease identifies GAPDH as a detergent-insoluble paired helical filament tau binding protein. FASEB J. 2005; 19:869-871.
45. Tatton NA. Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease. Exp. Neurol. 2000; 166: 29-43.
46. Ishitani R, Sunaga K, Hirano A, Saunders P, Katsube N, Chuang DM, Evidence that glyceraldehyde-3-phosphate dehydrogenase is involved in age-induced apoptosis in mature cerebellar neurons in culture. J. Neurochem. 1996; 66: 928-935.
47. Shalova IN, Cechalova K, Rehakova Z, Dimitrova P, Ognibene E, Caprioli A, Schmalhausen EV, Muronetz VI, Saso L. Decrease of dehydrogenase activity of cerebral glyceraldehyde-3-phosphate dehydrogenase in different animal models of Alzheimer's disease. Biochim. Biophys. Acta. 2007; 1770: 826-832.
48. Mazzola JL, Shover MA. Alteration of nuclear glyceraldehyde-3-phosphate dehydrogenase structure in Huntington's disease fibroblasts. Brain Res. Mol. Brain Res. 2002; 100: 95-101.
49. Boyd-Kimball D, Sultana R, Poon HF, Lynn BC, Casamenti F, Pepeu G, Klein JB, Butterfield DA. Proteomic identification of proteins specifically oxidized by intracerebral injection of amyloid beta-peptide (1-42) into rat brain: implications for Alzheimer's disease. Neuroscience 2005; 132: 313-324.
50. Arias C, Montiel T, Quiroz-Baez R, Massieu L. Beta-amyloid neurotoxicity is exacerbated during glycolysis inhibition and mitochondrial impairment in the rat hippocampus in vivo and in isolated nerve terminals: implications for Alzheimer's disease. Exp. Neurol. 2002; 176: 163-174.
51. Mosconi L. Brain glucose metabolism in the early and specific diagnosis of Alzheimer's disease. FDG-PET studies in MCI and AD. Eur. J. Nucl. Med. Mol. Imaging. 2005; 32: 486-510.
52. Cuervo AM, Stefanis L, Fredenburg R, Lansbury PT, Sulzer D. Impaired degradation of mutant alpha-synuclein by chaperone-mediated autophagy. Science 2004; 305: 1292-1295.
53. Nixon RA, Wegiel J, Kumar A, Yu WH, Peterhoff C, Cataldo A, Cuervo AM. Extensive involvement of autophagy in Alzheimer disease: an iromuno-electron microscopy study. J. Neuropathol. Exp. Neurol. 2005; 64: 113-122.