Characterization of a replicative DNA polymerase mutant with reduced fidelity and increased translesion synthesis capacity

Nucleic Acids Research

Volumn 36, Issue 12, 2008, Pages 3892-3904

  Zhong, Xuejun ^a   Pedersen, Lars C ^a   Kunkel, Thomas A ^a  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA POLYMERASE; GLYCINE; LEUCINE; NUCLEOTIDE; PHENYLALANINE;

ARTICLE; BACTERIAL CELL; BACTERIUM MUTANT; BASE PAIRING; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ESCHERICHIA COLI; GEOMETRY; KINETICS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN FAMILY; SITE DIRECTED MUTAGENESIS; WILD TYPE;

AMINO ACID SUBSTITUTION; BASE PAIR MISMATCH; CRYSTALLOGRAPHY, X-RAY; DNA; DNA DAMAGE; DNA REPLICATION; DNA-DIRECTED DNA POLYMERASE; GUANINE; KINETICS; MODELS, MOLECULAR; MUTATION; NUCLEOTIDES; TEMPLATES, GENETIC; VIRAL PROTEINS;

EID: 47249093333     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkn312     Document Type: Article

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